Effective April 1, 2026, Hideo Harigae was appointed Executive Director of the Tohoku University Tohoku Medical Megabank Organization.

The study found that adults with an anterior crossbite (but not anterior open bite) exhibited a higher likelihood of tooth loss and a 1.14-fold higher risk of losing molars after adjusting for age, sex, oral hygiene, caries, periodontal disease and lifestyle factors.

A research team has uncovered compelling evidence that maternal perinatal depression – psychological distress occurring during pregnancy or postpartum – elevates the risk of autistic-related traits in toddlers, with a particularly strong impact on girls.

After ten years of operating this ambitious project, we are sharing key insights regarding the techniques required to analyze, manage, maintain, and update a genomic database of 100,000 people.
The findings were published in JMA Journal on October 3, 2025.

New article about the Brain-MRI Study has been published in the Journal of the Japan Medical Association. The article describes the background, purpose, design, data management and reports on the results of the study.

ToMMo has successfully analyzed structural variations in the Japanese population using a long-read sequencer. This study was published in the journal Communications Biology on September 20, 2022. 

The article of the integrated database dbTMM for the Tohoku Medical Megabank Project has been published in Human Genome Variation.

The article about the design and pilot study for return of genomic results in Tohoku Medical Megabank (TMM) Project cohort study was published on the Journal of Human Genetics.

The Japanese now have their own reference genome thanks to researchers at ToMMo who completed and released the first Japanese reference genome (JG1). The study was published in the journal Nature Communications on January 11, 2021.

New article about study profile of The Tohoku Medical Megabank Community-Based Cohort Study was published on the Journal of Epidemiology.

New article about design and progress of oral health examinations in Tohoku Medical Megabank Project was published in the Tohoku Journal of Experimental Medicine.

The article about the public relations and communication strategies of Tohoku Medical Megabank Project was published

The article about the design of Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study was published.

New article about establishment and sample management of TMM biobank was published on the journal “The Tohoku Journal of Experimental Medicine”.

ToMMo Introduction Movie is available now!

You are able to know more about ToMMo, such as project overview, design, or facilities. Please visit the page “ToMMo’s Library”.

We published an article describing progress and perspectives of genomic research in Tohoku Medical Megabank Project.

The article about omics research project was published.

Article about design and mission of the Tohoku Medical Megabank Project was published.