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  • Cohort Study and Biobank

    Research Activities

    -We are studying the relationship between hereditary and environmental factors and disease incidence, in an attempt to predict disease risk and determine the causes of diseases. To this end, cohort studies are being performed in Miyagi and Iwate Prefectures.
    In addition, through analyses of the MRI images (brain and thigh) of some of the people taking part in the cohort studies, combined with analyses of their lifestyles, cognitive capacity, mental health status, and genome information, we are studying the effects that hereditary and environmental factors have on the brain and cognitive capacity, as well as the mechanisms of developing Posttraumatic Stress Reaction (PTSR), depression, and dementia.
    -We are now developing a biobank which collects and stores blood, urine and other biological specimens of the 150,000 people who will be participating in the cohort studies, as well as their health information and data from analyses that utilized these biological specimens. To ensure that research using these biological specimens and information contributes to development of future medicine, practical studies are being implemented on biobank management approaches.

    Key Word: cohort study, genome, population-based, three-generation, biobank, MRI

    Related information

    -Health surveillance of the brain and psychological state program with MRI

    -Return of Genomic Results to Cohort Study Participants


    • The Tohoku Medical Megabank Project: Design and Mission
    • Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project
    • Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design

    Click HERE for more publications related to cohort study and biobank in ToMMo.


    -Interview with Dr. Tomita from the Department of Disaster Psychiatry (Oct. 8, 2014)


    50,000 people have participated in the Tohoku Medical Megabank Project Community-Based Cohort Study in Miyagi Prefecture.

    Press Releases

    -ToMMo completed the ToMMo Child Health Study in Miyagi Prefecture during a period of four years after the Great East Earthquake (Apr. 5, 2016)
    -Depressive symptoms continue to be higher in coastal areas than in inland areas 3 years after the Great East Japan Earthquake (Mar. 16, 2016)
    -Psychological Consequences Remain Profound Among Coastal Communities Devastated by the Great East Japan Earthquake (Sep. 1, 2015)
    -Findings from the FY2013 Long-term community child health study (Jan. 17, 2014)
    -The first round of aggregate findings from the community resident cohort study in the first year-27% of study participants showed depressive tendencies, 5% showed signs of PTSD- (Feb. 27, 2014)


    50,000 people have participated in the Tohoku Medical Megabank Project Community-Based Cohort Study in Miyagi Prefecture (Nov. 4, 2015)

    The number of participants for the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study reached to 70,000 (Jan. 26 2017)