New article about transcriptome analysis using long-read sequencing technology was published on the Molecular and Cellular Biology.
Regulation of cytoprotective gene-expression is essential for our health. In this paper, in order to delineate precisely the transcript isoform usage in the stress response, we conducted a full-length transcriptome analysis using long-read sequencing technology. We determined the transcript isoform usages of genes related to the oxidative stress response. Our present study also argues that there are important benefits of long-read technology in the transcriptome analysis. This work was partly supported by AMED Platform Program for Promotion of Genome Medicine.
Please take a look at the article for more details. The transcriptome data are available at jMorp website HERE.
Title: Identification of dominant transcripts in oxidative stress response by a full-length transcriptome analysis
Authors: Akihito Otsuki, Yasunobu Okamura, Yuichi Aoki, Noriko Ishida, Kazuki Kumada, Naoko Minegishi, Fumiki Katsuoka, Kengo Kinoshita, Masayuki Yamamoto
Published journal: Molecular and Cellular Biology
Published date: November 9, 2020