Tohoku University Tohoku Medical Megabank Organization (Taku Obara)
2020.01.21

1.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2  
2.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0  
3.   Sakurai-Yageta Mika, Kawame Hiroshi, Kuriyama Shinichi, et al. A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization. BMC Medical Education. 2019; 19 (1): 297. doi:10.1186/s12909-019-1725-5  
4.   Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): bmjopen-2018-025939. doi:10.1136/bmjopen-2018-025939  
5.   Noda Aoi, Obara Taku, Abe Shinya, et al. The present situation of home blood pressure measurement among outpatients in Japan. Clinical and Experimental Hypertension. 2019; : 1-8. doi:10.1080/10641963.2019.1571601  
6.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Preconception folic acid supplementation use and the occurrence of neural tube defects in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study. Congenital anomalies. 2019; 59 (4): 110-117. doi:10.1111/cga.12293  
7.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Disaster Medicine and Public Health Preparedness. 2019; : 1-7. doi:10.1017/dmp.2019.8  
8.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2019; : 1-6. doi:10.1080/21645515.2019.1655833  
9.   Iwama Noriyuki, Metoki Hirohito, Nishigori Hidekazu, et al. Association between alcohol consumption during pregnancy and hypertensive disorders of pregnancy in Japan: the Japan Environment and Children's Study. Hypertension research : official journal of the Japanese Society of Hypertension. 2019; 42 (1): 85-94. doi:10.1038/s41440-018-0124-3  
10.   Tanaka Kosuke, Nishigori Hidekazu, Watanabe Zen, et al. Higher prevalence of hypertensive disorders of pregnancy in women who smoke: the Japan environment and children's study. Hypertension research : official journal of the Japanese Society of Hypertension. 2019; 42 (4): 558-566. doi:10.1038/s41440-019-0206-x  
11.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective. International Journal of Epidemiology. 2019; : . doi:10.1093/ije/dyz169  
12.   Yoshida Makiko, Obara Taku, Kikuchi Saya, et al. Drug Prescriptions for Children With ADHD in Japan: A Study Based on Health Insurance Claims Data Between 2005 and 2015. Journal of Attention Disorders. 2019; : 108705471984317. doi:10.1177/1087054719843179  
13.   Iwama Noriyuki, Metoki Hirohito, Nishigori Hidekazu, et al. Blood pressure changes during twin pregnancies: the Japan Environment and Children's Study. Journal of hypertension. 2019; 37 (1): 206-215. doi:10.1097/HJH.0000000000001846  
14.   Ishikawa Tomofumi, Obara Taku, Jin Kazutaka, et al. Examination of the prescription of antiepileptic drugs to prenatal and postpartum women in Japan from a health administrative database. Pharmacoepidemiology and Drug Safety. 2019; : . doi:10.1002/pds.4749  
15.   Tsuchiya Masami, Obara Taku, Sakai Takamasa, et al. Quality evaluation of the Japanese Adverse Drug Event Report database (JADER). Pharmacoepidemiology and drug safety. 2019; : . doi:10.1002/pds.4944  
16.   Hattori Hiromitsu, Kitamura Akane, Takahashi Fumiaki, et al. The risk of secondary sex ratio imbalance and increased monozygotic twinning after blastocyst transfer: data from the Japan Environment and Children's Study. Reproductive biology and endocrinology : RB&E. 2019; 17 (1): 27. doi:10.1186/s12958-019-0471-1  
17.   Ikeda-Sakai Yasuko, Saito Yoshiyuki, Obara Taku, et al. Inadequate Folic Acid Intake Among Women Taking Antiepileptic Drugs During Pregnancy in Japan: A Cross-Sectional Study. Scientific reports. 2019; 9 (1): 13497. doi:10.1038/s41598-019-49782-x  
18.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Mother-to-infant bonding failure and intimate partner violence during pregnancy as risk factors for father-to-infant bonding failure at 1 month postpartum: an adjunct study of the Japan Environment and Children’s Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2019; : 1-8. doi:10.1080/14767058.2018.1560414  
19.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. The prevalence and risk factors for postpartum depression symptoms of fathers at one and 6 months postpartum: an adjunct study of the Japan Environment & Children’s Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2019; : 1-8. doi:10.1080/14767058.2018.1560415  
20.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. Allergology International. 2018; 67 (4): 481-486. doi:10.1016/j.alit.2018.02.009  
21.   Imai Yutaka, Asayama Kei, Fujiwara Seisuke, et al. Development and evaluation of a home nocturnal blood pressure monitoring system using a wrist-cuff device. Blood pressure monitoring. 2018; 23 (6): 318-326. doi:10.1097/MBP.0000000000000351  
22.   Hosaka Miki, Inoue Ryusuke, Satoh Michihiro, et al. Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients. Clinical and experimental hypertension (New York, N.Y. : 1993). 2018; 40 (5): 468-475. doi:10.1080/10641963.2017.1403617  
23.   Ogata Soshiro, Kamide Kei, Asayama Kei, et al. Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study. Clinical and experimental hypertension (New York, N.Y. : 1993). 2018; 40 (4): 363-369. doi:10.1080/10641963.2017.1384481  
24.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Nocturnal blood pressure decline based on different time intervals and long-term cardiovascular risk: the Ohasama Study. Clinical and experimental hypertension (New York, N.Y. : 1993). 2018; 40 (1): 1-7. doi:10.1080/10641963.2016.1259324  
25.   Watabe Daisuke, Asayama Kei, Hanazawa Tomohiro, et al. Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study. Hypertension research : official journal of the Japanese Society of Hypertension. 2018; 41 (8): 622-628. doi:10.1038/s41440-018-0050-4  
26.   Ohseto Hisashi, Ishikuro Mami, Kikuya Masahiro, et al. Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study. Journal of psychosomatic research. 2018; 107 : 20-25. doi:10.1016/j.jpsychores.2018.01.013  
27.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Association Between Amplitude of Seasonal Variation in Self-Measured Home Blood Pressure and Cardiovascular Outcomes: HOMED-BP (Hypertension Objective Treatment Based on Measurement By Electrical Devices of Blood Pressure) Study. Journal of the American Heart Association. 2018; 7 (10): . doi:10.1161/JAHA.117.008509  
28.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Antihypertensives prescribed for pregnant women in Japan: Prevalence and timing determined from a database of health insurance claims. Pharmacoepidemiology and Drug Safety. 2018; 27 (12): 1325-1334. doi:10.1002/pds.4654  
29.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Development of algorithms to determine the onset of pregnancy and delivery date using health care administrative data in a university hospital in Japan. Pharmacoepidemiology and drug safety. 2018; 27 (7): 751-762. doi:10.1002/pds.4444  
30.   Obara Taku, Ishikuro Mami, Tamiya Gen, et al. Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports. 2018; 8 (1): 14840. doi:10.1038/s41598-018-33110-w  
31.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Update on the prevalence and determinants of folic acid use in Japan evaluated with 91,538 pregnant women: the Japan Environment and Children's Study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2018; : 1-10. doi:10.1080/14767058.2018.1494712  
32.   Ishikuro Mami, Obara Taku, Osanai Tamae, et al. Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2018; 246 (2): 97-105. doi:10.1620/tjem.246.97  
33.   Ishikuro Mami, Matsubara Hiroko, Kikuya Masahiro, et al. Disease prevalence among nursery school children after the Great East Japan earthquake. BMJ Global Health. 2017; 2 (2): e000127. doi:10.1136/bmjgh-2016-000127  
34.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Selective serotonin reuptake inhibitors and risk of major congenital anomalies for pregnancies in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study. Congenital Anomalies. 2017; 57 (3): 72-78. doi:10.1111/cga.12202  
35.   Sakurai Kasumi, Nishigori Hidekazu, Nishigori Toshie, et al. Incidence of Domestic Violence Against Pregnant Females After the Great East Japan Earthquake in Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (02): 216-226. doi:10.1017/dmp.2016.109  
36.   Nishigori Hidekazu, Nishigori Toshie, Sakurai Kasumi, et al. Pregnant Women’s Awareness of Social Capital in the Great East Japan Earthquake-Affected Areas of Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (03): 355-364. doi:10.1017/dmp.2016.150  
37.   Hidaka Hiroshi, Ozawa Daiki, Kuriyama Shinichi, et al. Risk factors for delayed oral dietary intake in patients with deep neck infections including descending necrotizing mediastinitis. European Archives of Oto-Rhino-Laryngology. 2017; 274 (11): 3951-3958. doi:10.1007/s00405-017-4716-3  
38.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Seasonal variation in self-measured home blood pressure among patients on antihypertensive medications: HOMED-BP study. Hypertension research : official journal of the Japanese Society of Hypertension. 2017; 40 (3): 284-290. doi:10.1038/hr.2016.133  
39.   Kikuya Masahiro, Matsubara Hiroko, Ishikuro Mami, et al. Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey. Journal of Epidemiology. 2017; 27 (10): 462-468. doi:10.1016/j.je.2016.09.012  
40.   Miyashita Masako, Ishikuro Mami, Kikuya Masahiro, et al. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. Journal of Pediatrics and Congenital Disorders. 2017; 4 : . http://www.jpediatrics.com/development-of-a-questionnaire-method-of-screening-for-citrin-deficiency-in-schoolchildren/  
41.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Drug Use before and during Pregnancy in Japan: The Japan Environment and Children's Study. Pharmacy. 2017; 5 (2): 21. doi:10.3390/pharmacy5020021  
42.   Obara Taku, Nishigori Hidekazu, Nishigori Toshie, et al. Prevalence and determinants of inadequate use of folic acid supplementation in Japanese pregnant women: the Japan Environment and Children’s Study (JECS). The Journal of Maternal-Fetal & Neonatal Medicine. 2017; 30 (5): 588-593. doi:10.1080/14767058.2016.1179273  
43.   Ishikuro Mami, Ramón Gutiérrez Ubeda Sergio, Obara Taku, et al. Exploring Risk Factors of Patient Falls: A Retrospective Hospital Record Study in Japan. The Tohoku Journal of Experimental Medicine. 2017; 243 (3): 195-203. doi:10.1620/tjem.243.195  
44.   Mizuno Satoshi, Nishigori Hidekazu, Sugiyama Takashi, et al. Association between social capital and the prevalence of gestational diabetes mellitus: An interim report of the Japan Environment and Children's Study. Diabetes research and clinical practice. 2016; 120 : 132-41. doi:10.1016/j.diabres.2016.07.020  
45.   Ishikuro Mami, Ubeda Sergio Ramón Gutiérrez, Obara Taku, et al. Knowledge, Attitude, and Practices Toward Blood Pressure Measurement at Home Among Japanese Nurses. Home healthcare now. 2016; 34 (4): 210-7. doi:10.1097/NHH.0000000000000357  
46.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Long-Term Stroke Risk Due to Partial White-Coat or Masked Hypertension Based on Home and Ambulatory Blood Pressure Measurements: The Ohasama Study. Hypertension. 2016; 67 (1): 48-55. doi:10.1161/HYPERTENSIONAHA.115.06461  
47.   Iwama Noriyuki, Metoki Hirohito, Ohkubo Takayoshi, et al. Maternal clinic and home blood pressure measurements during pregnancy and infant birth weight: the BOSHI study. Hypertension Research. 2016; 39 (3): 151-157. doi:10.1038/hr.2015.108  
48.   Ishikura Kazuki, Obara Taku, Kikuya Masahiro, et al. Home blood pressure level and decline in renal function among treated hypertensive patients: the J-HOME-Morning Study. Hypertension research : official journal of the Japanese Society of Hypertension. 2016; 39 (2): 107-12. doi:10.1038/hr.2015.110  
49.   Watanabe Zen, Iwama Noriyuki, Nishigori Hidekazu, et al. Psychological distress during pregnancy in Miyagi after the Great East Japan Earthquake: The Japan Environment and Children's Study. Journal of Affective Disorders. 2016; 190 : 341-348. doi:10.1016/j.jad.2015.10.024  
50.   Satoh Michihiro, Haga Toshikazu, Hosaka Miki, et al. The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements. Journal of Hypertension. 2016; 34 (6): 1218-1223. doi:10.1097/HJH.0000000000000902  
51.   Ishikuro Mami, Nakaya Naoki, Obara Taku, et al. Public Attitudes toward an Epidemiological Study with Genomic Analysis in the Great East Japan Earthquake Disaster Area. Prehospital and Disaster Medicine. 2016; 31 (3): 330-334. doi:10.1017/S1049023X16000182  
52.   Takahashi Fumiaki, Nishigori Hidekazu, Nishigori Toshie, et al. Fermented Food Consumption and Psychological Distress in Pregnant Women: A Nationwide Birth Cohort Study of the Japan Environment and Children’s Study. The Tohoku Journal of Experimental Medicine. 2016; 240 (4): 309-321. doi:10.1620/tjem.240.309  
53.   Satoh Michihiro, Obara Taku, Nishigori Hidekazu, et al. Prescription trends in children with pervasive developmental disorders: a claims data-based study in Japan. World journal of pediatrics : WJP. 2016; 12 (4): 443-449. doi:10.1007/s12519-016-0036-8  
54.   T Obara, H Yamaguchi, M Satoh, Y Iida. Prevalence, Determinants, and Reasons for the Non-Reporting of Adverse Drug Reactions by Pharmacists in the Miyagi and Hokkaido Regions of Japan. Advances in Pharmacoepidemiology & Drug Safety. 2015; 04 (05): . doi:10.4172/2167-1052.1000191  
55.   Satoh Michihiro, Kikuya Masahiro, Hosaka Miki, et al. Association of aldosterone-to-renin ratio with hypertension differs by sodium intake: the Ohasama study. American journal of hypertension. 2015; 28 (2): 208-15. doi:10.1093/ajh/hpu115  
56.   Metoki Hirohito, Obara Taku, Asayama Kei, et al. Differential effects of angiotensin II receptor blocker and losartan/hydrochlorothiazide combination on central blood pressure and augmentation index. Clinical and Experimental Hypertension. 2015; 37 (4): 294-302. doi:10.3109/10641963.2014.960972  
57.   Satoh Michihiro, Tanno Yumi, Hosaka Miki, et al. Salt intake and the validity of a salt intake assessment system based on a 24-h dietary recall method in pregnant Japanese women. Clinical and Experimental Hypertension. 2015; 37 (6): 459-462. doi:10.3109/10641963.2015.1057832  
58.   Nishigori Hidekazu, Sasaki Michiho, Obara Taku, et al. Correlation Between the Great East Japan Earthquake and Postpartum Depression: A Study in Miyako, Iwate, Japan. Disaster medicine and public health preparedness. 2015; 9 (3): 307-12. doi:0.1017/dmp.2015.51  
59.   Obara Taku, Ubeda Sergio Ramón Gutiérrez, Ohkubo Takayoshi, et al. Awareness of the Japanese Society of Hypertension Guidelines for the Management of Hypertension and their use in clinical practices: 2009 survey results. Hypertension Research. 2015; 38 (6): 400-404. doi:10.1038/hr.2015.21  
60.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Parity as a factor affecting the white-coat effect in pregnant women: the BOSHI study. Hypertension research : official journal of the Japanese Society of Hypertension. 2015; 38 (11): 770-5. doi:10.1038/hr.2015.97  
61.   Hosaka Miki, Metoki Hirohito, Satoh Michihiro, et al. Randomized trial comparing the velocities of the antihypertensive effects on home blood pressure of candesartan and candesartan with hydrochlorothiazide. Hypertension research : official journal of the Japanese Society of Hypertension. 2015; 38 (10): 701-7. doi:10.1038/hr.2015.64  
62.   Satoh Michihiro, Hosaka Miki, Asayama Kei, et al. Association between N-terminal pro B-type natriuretic peptide and day-to-day blood pressure and heart rate variability in a general population: the Ohasama study. Journal of Hypertension. 2015; 28 (2): 1. doi:10.1097/HJH.0000000000000570  
63.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Differences between clinic and home blood pressure measurements during pregnancy. Journal of hypertension. 2015; 33 (7): 1492-3. doi:10.1097/HJH.0000000000000608  
64.   Obara Taku, Abe Shinya, Satoh Michihiro, et al. Awareness regarding clinical application of pharmacogenetics among Japanese pharmacists. Pharmacogenomics and personalized medicine. 2015; 8 : 35-41. doi:10.2147/PGPM.S71813  
65.   Hasegawa Jun, Hidaka Hiroshi, Kuriyama Shinichi, et al. Change in and Long-Term Investigation of Neuro-Otologic Disorders in Disaster-Stricken Fukushima Prefecture: Retrospective Cohort Study before and after the Great East Japan Earthquake. PloS one. 2015; 10 (4): e0122631. doi:10.1371/journal.pone.0122631  
66.   Miyashita Masako, Kikuya Masahiro, Yamanaka Chizuru, et al. Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. The Tohoku Journal of Experimental Medicine. 2015; 237 (4): 297-305. doi:10.1620/tjem.237.297  
67.   Kikuya Masahiro, Miyashita Masako, Yamanaka Chizuru, et al. Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2015; 236 (2): 123-130. doi:10.1620/tjem.236.123  
68.   Nishigori Hidekazu, Sugawara Junichi, Obara Taku, et al. Surveys of postpartum depression in Miyagi, Japan, after the Great East Japan Earthquake. Archives of women's mental health. 2014; 17 (6): 579-81. doi:10.1007/s00737-014-0459-y  
69.   Matsumoto A., Satoh M., Kikuya M., et al. Day-to-Day Variability in Home Blood Pressure Is Associated With Cognitive Decline: The Ohasama Study. Hypertension. 2014; 63 (6): 1333-1338. doi:10.1161/HYPERTENSIONAHA.113.01819  
70.   Asayama Kei, Thijs Lutgarde, Brguljan-Hitij Jana, et al. Risk stratification by self-measured home blood pressure across categories of conventional blood pressure: a participant-level meta-analysis. PLoS medicine. 2014; 11 (1): e1001591. doi:10.1371/journal.pmed.1001591  
71.   Obara Taku, Kikuya Masahiro, Kobayashi Yuka, et al. Associations between visit-to-visit variability in blood pressure measured in the office and antihypertensive drugs: the J-HOME-Morning study. Clinical and experimental hypertension (New York, N.Y. : 1993). 2013; 35 (4): 285-90. doi:10.3109/10641963.2013.780070  
72.   Kanno Atsuhiro, Kikuya Masahiro, Asayama Kei, et al. Night-time blood pressure is associated with the development of chronic kidney disease in a general population: the Ohasama Study. Journal of hypertension. 2013; 31 (12): 2410-7. doi:10.1097/HJH.0b013e328364dd0f