Tohoku University Tohoku Medical Megabank Organization (Taku Obara)
2025.02.14

1.   Ishikuro Mami, Fuse Nobuo, Obara Taku, et al. Parental axial lengths and prenatal conditions related to child axial length: The TMM BirThree Cohort Study. AJO International. 2025; 2 (1): 100088. doi:10.1016/j.ajoint.2024.100088  
2.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Association Between Sodium- and Potassium-Related Urinary Markers and the Prevalence of Atrial Fibrillation. Circulation Journal. 2025; : CJ-24-0780. doi:10.1253/circj.CJ-24-0780  
3.   Ishikuro Mami, Obara Taku, Hasegawa Mayu, et al. Subsequent high blood pressure and hypertension by hypertensive disorders of pregnancy: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Hypertension Research. 2025; 48 (1): 68-76. doi:10.1038/s41440-024-01936-9  
4.   Nakatochi Masahiro, Kushima Itaru, Aleksic Branko, et al. Copy number variations in RNF216 and postsynaptic membrane–associated genes are associated with bipolar disorder: a case‐control study in the Japanese population. Psychiatry and Clinical Neurosciences. 2025; 79 (1): 12-20. doi:10.1111/pcn.13752  
5.   Kawaguchi Chikana, Ishikuro Mami, Saito Ryota, et al. Maternal Fasting Plasma Glucose Level in Early Gestation and Developmental Delay in 2-year-old Children. The Journal of Clinical Endocrinology & Metabolism. 2025; : . doi:10.1210/clinem/dgae825  
6.   Chen Geng, Ishikuro Mami, Ohseto Hisashi, et al. Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Acta Obstetricia et Gynecologica Scandinavica. 2024; 103 (6): 1192-1200. doi:10.1111/aogs.14820  
7.   Ishikawa Tomofumi, Sakai Takamasa, Iwama Noriyuki, et al. Association between exposure to atypical antipsychotics during pregnancy and risk of miscarriage. Acta Psychiatrica Scandinavica. 2024; 150 (6): 562-572. doi:10.1111/acps.13755  
8.   Mizuno Satoshi, Nagaie Satoshi, Sugawara Junichi, et al. Early prediction of hypertensive disorders of pregnancy toward preventive early intervention. AJOG Global Reports. 2024; 4 (4): 100383. doi:10.1016/j.xagr.2024.100383  
9.   Kawaguchi Chikana, Ozawa Maki, Hidaka Takanori, et al. Skin health survey on atopic dermatitis among Japanese children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Allergology International. 2024; : . doi:10.1016/j.alit.2024.09.008  
10.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between leisure time, non-leisure time physical activity, and kidney function in Japanese adults: a cross-sectional study. BMC Nephrology. 2024; 25 (1): 354. doi:10.1186/s12882-024-03813-6  
11.   Yonezawa Yudai, Takahashi Ippei, Ohseto Hisashi, et al. Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2024; 24 (1): 209. doi:10.1186/s12884-024-06376-4  
12.   Takayama Jun, Makino Satoshi, Funayama Takamitsu, et al. A fine‐scale genetic map of the Japanese population. Clinical Genetics. 2024; 106 (3): 284-292. doi:10.1111/cge.14536  
13.   Obara Taku. Directions for perinatal pharmacoepidemiology studies in Japan. Congenital Anomalies. 2024; 64 (1): 4-5. doi:10.1111/cga.12549  
14.   Ohseto Hisashi, Takahashi Ippei, Narita Akira, et al. Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory. Depression and Anxiety. 2024; 2024 : 1-13. doi:10.1155/2024/6622666  
15.   Hashimoto Hideaki, Satoh Michihiro, Nakayama Shingo, et al. Comparison of renal prognosis between dipeptidyl peptidase‐4 inhibitor users and non‐users. Diabetes, Obesity and Metabolism. 2024; 26 (10): 4460-4467. doi:10.1111/dom.15800  
16.   石黒 真美, 小原 拓, 黒田 真帆, et al. 東北メディカル・メガバンク計画三世代コホート調査:10年間の取り組みと周産期転帰のプロファイル. DOHaD研究. 2024; 12 (1): 11-17. doi:10.51067/dohad.12.1_11  
17.   Noda Aoi, Obara Taku, Matsuzaki Fumiko, et al. Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy. Drugs - Real World Outcomes. 2024; 11 (2): 263-272. doi:10.1007/s40801-023-00411-0  
18.   Tokunaga Misaki, Kikuchi Daisuke, Noda Aoi, et al. Trends in Anti-Influenza Drug Prescription and Adverse Drug Reaction Reporting After the Lifting of Oseltamivir Prescribing Restrictions in Pediatric Outpatients: An Ecological Study Using the MDV Analyzer® And the Japanese Adverse Drug Event Report Datab. Drugs - Real World Outcomes. 2024; 11 (2): 177-184. doi:10.1007/s40801-023-00414-x  
19.   Izumi Seiya, Iwama Noriyuki, Hamada Hirotaka, et al. Associations of fasting plasma glucose and glycosylated hemoglobin levels at less than 24 weeks of gestation with hypertensive disorders of pregnancy: the BOSHI study. Endocrine Journal. 2024; 71 (10): EJ23-0568. doi:10.1507/endocrj.EJ23-0568  
20.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal social isolation and behavioral problems in preschool children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Child & Adolescent Psychiatry. 2024; 33 (3): 761-769. doi:10.1007/s00787-023-02199-4  
21.   Noda Aoi, Obara Taku, Shirota Matsuyuki, et al. Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Pharmacology. 2024; 80 (8): 1171-1180. doi:10.1007/s00228-024-03685-7  
22.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between housing and psychological damage by earthquake and modifiable risk factors for dementia in general older adults: Tohoku Medical Megabank community‐based cohort study. Geriatrics & Gerontology International. 2024; 24 (6): 509-516. doi:10.1111/ggi.14867  
23.   Takahashi Ippei, Ohseto Hisashi, Ueno Fumihiko, et al. Genome-wide association study based on clustering by obesity-related variables uncovers a genetic architecture of obesity in the Japanese and the UK populations. Heliyon. 2024; 10 (16): e36023. doi:10.1016/j.heliyon.2024.e36023  
24.   Takase Masato, Hirata Takumi, Nakaya Naoki, et al. Associations of combined genetic and lifestyle risks with hypertension and home hypertension. Hypertension Research. 2024; 47 (8): 2064-2074. doi:10.1038/s41440-024-01705-8  
25.   Toyama Maya, Satoh Michihiro, Nakayama Shingo, et al. Combined effects of blood pressure and glucose status on the risk of chronic kidney disease. Hypertension Research. 2024; 47 (7): 1831-1841. doi:10.1038/s41440-024-01683-x  
26.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Depressive symptoms as risk factors for the onset of home hypertension: a prospective cohort study. Hypertension Research. 2024; 47 (11): 2989-3000. doi:10.1038/s41440-024-01790-9  
27.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study. Hypertension Research. 2024; 47 (6): 1533-1545. doi:10.1038/s41440-024-01582-1  
28.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. The association between blood pressure control in women during pregnancy and adverse perinatal outcomes: the TMM BirThree Cohort Study. Hypertension Research. 2024; 47 (5): 1216-1222. doi:10.1038/s41440-023-01570-x  
29.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center. Hypertension Research. 2024; 47 (3): 586-597. doi:10.1038/s41440-023-01484-8  
30.   Himuro Hiromi, Kogure Mana, Nakaya Naoki, et al. The association of birth weight and current BMI on the risk of hypertension: the Tohoku medical megabank community-based cohort study. Hypertension Research. 2024; 47 (11): 3025-3034. doi:10.1038/s41440-024-01827-z  
31.   Satoh Michihiro, Muroya Tomoko, Murakami Takahisa, et al. The impact of clinical inertia on uncontrolled blood pressure in treated hypertension: real-world, longitudinal data from Japan. Hypertension Research. 2024; 47 (3): 598-607. doi:10.1038/s41440-023-01452-2  
32.   Kikuchi Daisuke, Obara Taku, Suzuki Hiroyuki, et al. Trends in prescribing nifedipine and amlodipine to pregnant women after related contraindications were lifted in Japan. Hypertension Research. 2024; 47 (10): 2971-2973. doi:10.1038/s41440-024-01821-5  
33.   Takahashi Ippei, Obara Taku, Kuriyama Shinichi. Role of Genetic Risk in the Association Between Screen Time and Child Development. JAMA Pediatrics. 2024; 178 (3): 317. doi:10.1001/jamapediatrics.2023.6106  
34.   Orui Masatsugu, Obara Taku, Ishikuro Mami. How Healthy Lifestyle Habits Have Interacted with SARS-CoV-2 Infection and the Effectiveness of COVID-19 Vaccinations: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. JMA Journal. 2024; 7 (3): 353-363. doi:10.31662/jmaj.2024-0043  
35.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Genetic Risk, Healthy Lifestyle Adherence, and Risk of Developing Diabetes in the Japanese Population. Journal of Atherosclerosis and Thrombosis. 2024; 31 (12): 64906. doi:10.5551/jat.64906  
36.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2024; 31 (6): 64535. doi:10.5551/jat.64535  
37.   Kudo Rie, Iwama Noriyuki, Hamada Hirotaka, et al. Maternal birth weight is an indicator of preterm delivery: the Japan environment and children’s study. Journal of Developmental Origins of Health and Disease. 2024; 15 : e11. doi:10.1017/S2040174424000126  
38.   Tagami Kazuma, Iwama Noriyuki, Hamada Hirotaka, et al. Maternal birth weight as an indicator of early and late gestational diabetes mellitus: The Japan Environment and Children's Study. Journal of Diabetes Investigation. 2024; 15 (6): 751-761. doi:10.1111/jdi.14159  
39.   Hozawa Atsushi, Nakaya Kumi, Nakaya Naoki, et al. Progress Report of the Tohoku Medical Megabank Community-based Cohort Study: Study Profile of the Repeated Center-based Survey During Second Period in Miyagi Prefecture. Journal of Epidemiology. 2024; 34 (9): JE20230241. doi:10.2188/jea.JE20230241  
40.   Murakami Keiko, Ishihara Junko, Takachi Ribeka, et al. Validity and Reproducibility of Food Group Intakes in a Self-administered Food Frequency Questionnaire for Genomic and Omics Research: The Tohoku Medical Megabank Project. Journal of Epidemiology. 2024; : JE20240064. doi:10.2188/jea.JE20240064  
41.   Murakami Keiko, Nakadate Misako, Obara Taku, et al. Validity of a self-administered food frequency questionnaire for genomic and omics research among pregnant women: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2024; : JE20240293. doi:10.2188/jea.JE20240293  
42.   Takahashi Sayumi, Kakuta Yoichi, Obara Taku, et al. Prescribing in pregnant women with inflammatory bowel disease and its relationship to congenital malformations in Japan. Journal of Gastroenterology and Hepatology. 2024; 39 (7): 1291-1298. doi:10.1111/jgh.16549  
43.   Ishikuro Mami, Nishimura Tomoko, Iwata Hiroyoshi, et al. Association between infertility treatment and hypertensive disorders of pregnancy in the Japan Birth Cohort Consortium: a meta-analysis. Journal of Human Hypertension. 2024; 38 (2): 187-190. doi:10.1038/s41371-023-00890-2  
44.   Usuzaki Takuma, Inamori Ryusei, Ishikuro Mami, et al. Predicting EGFR Status After Radical Nephrectomy or Partial Nephrectomy for Renal Cell Carcinoma on CT Using a Self-attention-based Model: Variable Vision Transformer (vViT). Journal of Imaging Informatics in Medicine. 2024; 37 (6): 3057-3069. doi:10.1007/s10278-024-01180-0  
45.   Tsuchiya Masami, Kikuchi Daisuke, Hatakeyama Shiro, et al. Trend analysis of pharmacist involvement in cancer care in Japan from 2015 to 2020: A nationwide survey study on hospital pharmacy practice. Journal of Oncology Pharmacy Practice. 2024; : . doi:10.1177/10781552241263997  
46.   Tasaka Yuichi, Uchikura Takeshi, Hatakeyama Shiro, et al. Evaluation of hospital pharmacists’ activities using additional reimbursement for infection prevention as an indicator in small and medium-sized hospitals. Journal of Pharmaceutical Health Care and Sciences. 2024; 10 (1): 6. doi:10.1186/s40780-023-00327-5  
47.   Kikuchi Daisuke, Obara Taku, Obara Ryo, et al. Temporal trends in antipsychotic prescriptions for pediatric patients using an administrative hospital database in Japan: a retrospective study. Journal of Pharmaceutical Health Care and Sciences. 2024; 10 (1): 2. doi:10.1186/s40780-023-00324-8  
48.   Takahashi Ippei, Obara Taku, Ishikuro Mami, et al. Prospective associations of screen time at age 2 with specific behavioral subscales at age 3: a cohort study. Journal of Public Health. 2024; 46 (4): 477-486. doi:10.1093/pubmed/fdae240  
49.   Usuzaki Takuma, Inamori Ryusei, Shizukuishi Takashi, et al. Predicting isocitrate dehydrogenase status among adult patients with diffuse glioma using patient characteristics, radiomic features, and magnetic resonance imaging: Multi-modal analysis by variable vision transformer. Magnetic Resonance Imaging. 2024; 111 : 266-276. doi:10.1016/j.mri.2024.05.012  
50.   Usuzaki Takuma, Takahashi Kengo, Inamori Ryusei, et al. Identifying key factors for predicting O6-Methylguanine-DNA methyltransferase status in adult patients with diffuse glioma: a multimodal analysis of demographics, radiomics, and MRI by variable Vision Transformer. Neuroradiology. 2024; 66 (5): 761-773. doi:10.1007/s00234-024-03329-8  
51.   Hamada Hirotaka, Iwama Noriyuki, Tomita Hasumi, et al. Association between Maternal Birth Weight and Prevalence of Congenital Malformations in Offspring: The Japanese Environment and Children’s Study. Nutrients. 2024; 16 (4): 531. doi:10.3390/nu16040531  
52.   Ishitsuka Kazue, Piedvache Aurélie, Kobayashi Sumitaka, et al. The Population-Attributable Fractions of Small-for-Gestational-Age Births: Results from the Japan Birth Cohort Consortium. Nutrients. 2024; 16 (2): 186. doi:10.3390/nu16020186  
53.   Noda Aoi, Arita Ryutaro, Obara Taku, et al. The Use of Japanese Traditional (Kampo) Medicines Before and During Pregnancy in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Pharmacoepidemiology and Drug Safety. 2024; 33 (10): . doi:10.1002/pds.70033  
54.   Benton Madeleine, Ishikuro Mami, Obara Taku, et al. The effect of gestational diabetes mellitus on postnatal mother-infant bonding: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Preventive Medicine. 2024; 187 : 108101. doi:10.1016/j.ypmed.2024.108101  
55.   Li Xue, Takahashi Nagahide, Narita Akira, et al. Identification of risk loci for postpartum depression in a genome‐wide association study. Psychiatry and Clinical Neurosciences. 2024; 78 (11): 712-720. doi:10.1111/pcn.13731  
56.   Takahashi Ippei, Obara Taku, Kikuchi Saya, et al. Combination of taking neuropsychiatric medications and psychological distress in pregnant women, with behavioral problems in children at 2 years of age: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Psychiatry and Clinical Neurosciences Reports. 2024; 3 (3): . doi:10.1002/pcn5.226  
57.   Orui Masatsugu, Obara Taku, Ishikuro Mami, et al. Evaluation of depression at 6 and 12 months postpartum by examining depressive symptoms and self‐harm ideation during the early postpartum period: Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Psychiatry and Clinical Neurosciences Reports. 2024; 3 (4): . doi:10.1002/pcn5.70025  
58.   Matsushima Midori, Obara Taku, Ishikuro Mami, et al. Birth Weight and Labor Market Outcomes: Findings From Tohoku Medical Megabank Data. Public Health Challenges. 2024; 3 (3): . doi:10.1002/puh2.221  
59.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Genetic Risk, Lifestyle Adherence, and Risk of Developing Hyperuricaemia in a Japanese Population. Rheumatology. 2024; : . doi:10.1093/rheumatology/keae492  
60.   Usuzaki Takuma, Ishikuro Mami, Kikuya Masahiro, et al. Child-parent associations of hematocrit in trios of Japanese adulthood confirmed by the random family method: The TMM BirThree Cohort Study. Scientific Reports. 2024; 14 (1): 19047. doi:10.1038/s41598-024-69752-2  
61.   Mizuno Satoshi, Wagata Maiko, Nagaie Satoshi, et al. Development of phenotyping algorithms for hypertensive disorders of pregnancy (HDP) and their application in more than 22,000 pregnant women. Scientific Reports. 2024; 14 (1): 6292. doi:10.1038/s41598-024-55914-9  
62.   Sakurai Miyuki, Motoike Ikuko N., Hishinuma Eiji, et al. Identifying critical age and gender-based metabolomic shifts in a Japanese population of the Tohoku Medical Megabank cohort. Scientific Reports. 2024; 14 (1): 15681. doi:10.1038/s41598-024-66180-0  
63.   Kobayashi Masayuki, Ishikuro Mami, Obara Taku, Kuriyama Shinichi. Weight‐for‐age z ‐scores of Japanese children using the World Health Organization Child Growth Standards. Acta Paediatrica. 2023; 112 (4): 776-778. doi:10.1111/apa.16662  
64.   Someko Hidehiro, Kataoka Yuki, Obara Taku. Drug fever: a narrative review. Annals of Clinical Epidemiology. 2023; 5 (4): 23013. doi:10.37737/ace.23013  
65.   Machida Toshiya, Obara Taku, Ishikuro Mami, et al. Liver steatosis and fibrosis markers’ association with cardiovascular and renal damage in Japanese adults: the TMM BirThree cohort study. Annals of Hepatology. 2023; 28 (1): 100761. doi:10.1016/j.aohep.2022.100761  
66.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal postnatal bonding disorder and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2023; 26 (2): 219-226. doi:10.1007/s00737-023-01298-0  
67.   Ishikawa Tomofumi, Kawame Hiroshi, Mano Nariyasu, Obara Taku. Real‐world prevalence, time of diagnosis, and co‐occurrence patterns of birth defects in live‐born infants, 2014–2020: A health administrative database study in Japan. Birth Defects Research. 2023; 115 (18): 1723-1736. doi:10.1002/bdr2.2247  
68.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and infant birth weight: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Pregnancy and Childbirth. 2023; 23 (1): 268. doi:10.1186/s12884-023-05603-8  
69.   Mizuno Satoshi, Nagaie Satoshi, Tamiya Gen, et al. Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy and Childbirth. 2023; 23 (1): 628. doi:10.1186/s12884-023-05919-5  
70.   Matsuda Ayako, Asayama Kei, Obara Taku, et al. Behavioral changes of preventive activities of influenza among children in satellite cities of a metropolitan area of Tokyo, Japan, by the COVID-19 pandemic. BMC Public Health. 2023; 23 (1): 727. doi:10.1186/s12889-023-15606-x  
71.   Tsuchiya Masami, Obara Taku, Kikuchi Masafumi, Mano Nariyasu. The prevalence of end-of-life chemotherapy and targeted therapy in Japan, assessed using a health claims database. Cancer Chemotherapy and Pharmacology. 2023; 91 (6): 501-506. doi:10.1007/s00280-023-04535-6  
72.   Shinoda Genki, Nagaoka Yudai, Ueno Fumihiko, et al. Association between being Overweight in Young Childhood and during School Age and Puberty. Children. 2023; 10 (5): 909. doi:10.3390/children10050909  
73.   Ueno Fumihiko, Murakami Keiko, Nagai Masato, et al. Difficulties in Accessing Medication Records at the Time of a Large-Scale Disaster. Disaster Medicine and Public Health Preparedness. 2023; 17 : e370. doi:10.1017/dmp.2022.301  
74.   Usuzaki Takuma, Takahashi Kengo, Takagi Hidenobu, et al. Efficacy of exponentiation method with a convolutional neural network for classifying lung nodules on CT images by malignancy level. European Radiology. 2023; 33 (12): 9309-9319. doi:10.1007/s00330-023-09946-w  
75.   Li Xue, Ono Chiaki, Warita Noriko, et al. Comprehensive evaluation of machine learning algorithms for predicting sleep–wake conditions and differentiating between the wake conditions before and after sleep during pregnancy based on heart rate variability. Frontiers in Psychiatry. 2023; 14 : . doi:10.3389/fpsyt.2023.1104222  
76.   Obara Taku, Ishikuro Mami, Ueno Fumihiko, et al. Antihypertensive drug use during pregnancy in Japan. Hypertension Research. 2023; 46 (2): 548-549. doi:10.1038/s41440-022-01101-0  
77.   Suenaga Tsukasa, Satoh Michihiro, Murakami Takahisa, et al. Cross-classification by systolic and diastolic blood pressure levels and chronic kidney disease, proteinuria, or kidney function decline. Hypertension Research. 2023; 46 (8): 1860-1869. doi:10.1038/s41440-023-01267-1  
78.   Tanaka Kosuke, Nishigori Hidekazu, Watanabe Zen, et al. Secondhand smoke exposure is associated with the risk of hypertensive disorders of pregnancy: the Japan Environment and Children’s Study. Hypertension Research. 2023; 46 (4): 834-844. doi:10.1038/s41440-022-01144-3  
79.   Hatanaka Rieko, Nakaya Naoki, Kogure Mana, et al. The risk of withdrawal from hypertension treatment in coastal areas after the Great East Japan Earthquake: the TMM CommCohort Study. Hypertension Research. 2023; 46 (12): 2718-2728. doi:10.1038/s41440-023-01454-0  
80.   Takahashi Ippei, Obara Taku, Ishikuro Mami, et al. Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years. JAMA Pediatrics. 2023; 177 (10): 1039. doi:10.1001/jamapediatrics.2023.3057  
81.   Moroi Rintaro, Kakuta Yoichi, Obara Taku, et al. Long‐term prognosis and clinical practice for new‐onset ulcerative colitis in the era of biologics: A Japanese retrospective study. JGH Open. 2023; 7 (10): 682-689. doi:10.1002/jgh3.12957  
82.   Taira Makiko, Mugikura Shunji, Mori Naoko, et al. Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study: Rationale, Design, and Background. JMA Journal. 2023; 6 (3): 246-264. doi:10.31662/jmaj.2022-0220  
83.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal postnatal bonding disorder and emotional/behavioral problems in preschool children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 325 : 582-587. doi:10.1016/j.jad.2023.01.044  
84.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Traumatic experiences of the Great East Japan Earthquake and postpartum depressive symptoms: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 320 : 461-467. doi:10.1016/j.jad.2022.09.139  
85.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. Association of Central Blood Pressure and Carotid Intima Media Thickness with New-Onset Hypertension in People with High Normal Blood Pressure. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64151. doi:10.5551/jat.64151  
86.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64425. doi:10.5551/jat.64425  
87.   Tomita Hasumi, Iwama Noriyuki, Hamada Hirotaka, et al. The impact of maternal and paternal birth weights on infant birth weights: the Japan environment and children’s study. Journal of Developmental Origins of Health and Disease. 2023; 14 (6): 699-710. doi:10.1017/S2040174423000387  
88.   Morisaki Naho, Obara Taku, Piedvache Aurelie, et al. Association Between Smoking and Hypertension in Pregnancy Among Japanese Women: A Meta-analysis of Birth Cohort Studies in the Japan Birth Cohort Consortium (JBiCC) and JECS. Journal of Epidemiology. 2023; 33 (10): JE20220076. doi:10.2188/jea.JE20220076  
89.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Factors Associated With Postpartum Smoking Relapse Among Women Who Quit in Early Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (1): JE20200609. doi:10.2188/jea.JE20200609  
90.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Relation of Disaster Exposure With Maternal Characteristics and Obstetric Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (3): JE20210052. doi:10.2188/jea.JE20210052  
91.   Yashima K., Noda A., Ishikawa T., et al. Safety evaluation of the use of calcineurin inhibitor to prenatal and postpartum women in Japan from a health administrative database. Journal of Neonatal-Perinatal Medicine. 2023; 16 (3): 461-473. doi:10.3233/NPM-230138  
92.   Takahashi Ippei, Obara Taku, Kikuchi Saya, et al. Association between maternal psychological distress and children's neurodevelopment in offspring aged 4 years in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Journal of Paediatrics and Child Health. 2023; 59 (3): 548-554. doi:10.1111/jpc.16353  
93.   Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of Education and Income with Secondhand Smoke Exposure Among Non-smoking Pregnant Women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Maternal and Child Health Journal. 2023; 27 (7): 1238-1246. doi:10.1007/s10995-023-03648-x  
94.   Tagami Kazuma, Iwama Noriyuki, Hamada Hirotaka, et al. Maternal birth weight as an indicator of early-onset and late-onset hypertensive disorders of pregnancy: The Japan Environment and Children’s study. Pregnancy Hypertension. 2023; 34 : 159-168. doi:10.1016/j.preghy.2023.11.002  
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