Tohoku University Tohoku Medical Megabank Organization (Takako Takai-Igarashi)
2019.09.13

1.   Sakurai-Yageta Mika, Kawame Hiroshi, Kuriyama Shinichi, et al. A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization. BMC Medical Education. 2019; 19 (1): 297. doi:10.1186/s12909-019-1725-5  
2.   Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): bmjopen-2018-025939. doi:10.1136/bmjopen-2018-025939  
3.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective. International Journal of Epidemiology. 2019; : . doi:10.1093/ije/dyz169  
4.   Sakurai Rieko, Ueki Masao, Makino Satoshi, et al. Outlier detection for questionnaire data in biobanks. International Journal of Epidemiology. 2019; : . doi:10.1093/ije/dyz012  
5.   Miura Emiri, Tsuchiya Naho, Igarashi Yu, et al. Respiratory resistance among adults in a population-based cohort study in Northern Japan. Respiratory Investigation. 2019; 57 (3): 274-281. doi:10.1016/j.resinv.2018.12.008  
6.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096  
7.   Tanikawa Chizu, Kamatani Yoichiro, Toyoshima Osamu, et al. Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21. Cancer science. 2018; 109 (12): 4015-4024. doi:10.1111/cas.13815  
8.   Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588  
9.   Yamaguchi-Kabata Yumi, Yasuda Jun, Tanabe Osamu, et al. Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals. Journal of Human Genetics. 2018; 63 (2): 213-230. doi:10.1038/s10038-017-0347-1  
10.   Yuan Xunmei, Tsujimoto Kazutaka, Hashimoto Koshi, et al. Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood. Nature communications. 2018; 9 (1): 636. doi:10.1038/s41467-018-03038-w  
11.   Takai-Igarashi Takako, Kinoshita Kengo, Nagasaki Masao, et al. Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design. BMC Medical Informatics and Decision Making. 2017; 17 (1): 100. doi:10.1186/s12911-017-0494-5  
12.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268  
13.   Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463  
14.   Sawai Hashime, Takai-Igarashi Takako, Tanaka Hiroshi. Identification of collaborative activities with oxidative phosphorylation in bipolar disorder. Bioinformation. 2015; 11 (4): 207-216. doi:10.6026/97320630011207  
15.   Ehara Tatsuya, Kamei Yasutomi, Yuan Xunmei, et al. Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver. Diabetes. 2015; 64 (3): 775-784. doi:10.2337/db14-0158  
16.   Suzuki Asami, Takai-Igarashi Takako, Nakaya Jun, Tanaka Hiroshi. Development of an Ontology for Periodontitis. Journal of Biomedical Semantics. 2015; 6 (1): 30. doi:10.1186/s13326-015-0028-y  
17.   Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature communications. 2015; 6 : 8018. doi:10.1038/ncomms9018  
18.   Hori-Tanaka Yasuha, Yura Kei, Takai-Igarashi Takako, Tanaka Hiroshi. Structural classification of steroid-binding sites on proteins by coarse-grained atomic environment and its correlation with their biological function. Steroids. 2015; 96 : 81-88. doi:10.1016/j.steroids.2015.01.015  
19.   Ogishima Soichi, Takai Takako, Shimokawa Kazuro, et al. Integrated Database And Knowledge Base For Genomic Prospective Cohort Study In Tohoku Medical Megabank Toward Personalized Prevention And Medicine. Studies in health technology and informatics. 2015; 216 : 1057. doi:10.3233/978-1-61499-564-7-1057  
20.   Iwasaki Y., Suganami T., Hachiya R., et al. Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages. Diabetes. 2014; 63 (1): 152-161. doi:10.2337/db13-0757  
21.   Hatazawa Yukino, Tadaishi Miki, Nagaike Yuta, et al. PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle. PLoS ONE. 2014; 9 (3): e91006. doi:10.1371/journal.pone.0091006  
22.   Takahashi Mayumi, Kamei Yasutomi, Ehara Tatsuya, et al. Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes. Biochemical and Biophysical Research Communications. 2013; 434 (4): 873-878. doi:10.1016/j.bbrc.2013.04.041  
23.   Suzuki Satoru, Takai-Igarashi Takako, Fukuoka Yutaka, et al. Systems analysis of inflammatory bowel disease based on comprehensive gene information. BMC Medical Genetics. 2012; 13 (1): 25. doi:10.1186/1471-2350-13-25