Tohoku University Tohoku Medical Megabank Organization (Shigeo Kure)
2020.01.28

1.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2  
2.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0  
3.   Iwasawa Shinya, Yanagi Kumiko, Kikuchi Atsuo, et al. Recurrent de novo MAPK8IP3 variants cause neurological phenotypes. Annals of neurology. 2019; 85 (6): 927-933. doi:10.1002/ana.25481  
4.   Isojima Tsuyoshi, Kato Noriko, Yokoya Susumu, et al. Early excessive growth with distinct seasonality in preschool obesity. Archives of disease in childhood. 2019; 104 (1): 53-57. doi:10.1136/archdischild-2018-314862  
5.   Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): bmjopen-2018-025939. doi:10.1136/bmjopen-2018-025939  
6.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Disaster Medicine and Public Health Preparedness. 2019; : 1-7. doi:10.1017/dmp.2019.8  
7.   Wada Yoichi, Kikuchi Atsuo, Arai-Ichinoi Natsuko, et al. Biallelic GALM pathogenic variants cause a novel type of galactosemia. Genetics in Medicine. 2019; 21 (6): 1286-1294. doi:10.1038/s41436-018-0340-x  
8.   Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7  
9.   Nagasaki Masao, Kuroki Yoko, Shibata Tomoko F, et al. Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. Human Genome Variation. 2019; 6 (1): 27. doi:10.1038/s41439-019-0057-7  
10.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2019; : 1-6. doi:10.1080/21645515.2019.1655833  
11.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective. International Journal of Epidemiology. 2019; : . doi:10.1093/ije/dyz169  
12.   Fuse Nobuo, Sakurai-Yageta Mika, Katsuoka Fumiki, et al. Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project. JMA Journal. 2019; 2 (2): 113-122. doi:10.31662/jmaj.2019-0014  
13.   Igarashi Ayaka, Aida Jun, Sairenchi Toshimi, et al. Does Cigarette Smoking Increase Traffic Accident Death During 20 Years Follow-up in Japan? The Ibaraki Prefectural Health Study. Journal of epidemiology. 2019; 29 (5): 192-196. doi:10.2188/jea.JE20170330  
14.   Kikuchi Koichi, Saigusa Daisuke, Kanemitsu Yoshitomi, et al. Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. Nature Communications. 2019; 10 (1): 1835. doi:10.1038/s41467-019-09735-4  
15.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096  
16.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. Allergology International. 2018; 67 (4): 481-486. doi:10.1016/j.alit.2018.02.009  
17.   Ono Atsushi, Isojima Tsuyoshi, Yokoya Susumu, et al. Effect of the Fukushima earthquake on weight in early childhood: a retrospective analysis. BMJ paediatrics open. 2018; 2 (1): e000229. doi:10.1136/bmjpo-2017-000229  
18.   Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588  
19.   Kato N, Isojima T, Yokoya S, et al. Earlier BMI rebound and lower pre-rebound BMI as risk of obesity among Japanese preschool children. International Journal of Obesity. 2018; 42 (1): 52-58. doi:10.1038/ijo.2017.242  
20.   Yokomichi Hiroshi, Matsubara Hiroko, Ishikuro Mami, et al. Impact of the Great East Japan Earthquake on Body Mass Index, Weight, and Height of Infants and Toddlers: An Infant Survey. Journal of Epidemiology. 2018; 28 (5): 237-244. doi:10.2188/jea.JE20170006  
21.   Yamaguchi-Kabata Yumi, Yasuda Jun, Tanabe Osamu, et al. Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals. Journal of Human Genetics. 2018; 63 (2): 213-230. doi:10.1038/s10038-017-0347-1  
22.   Obara Taku, Ishikuro Mami, Tamiya Gen, et al. Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports. 2018; 8 (1): 14840. doi:10.1038/s41598-018-33110-w  
23.   Katayama Saori, Suzuki Mikiko, Yamaoka Ayaka, et al. GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. Blood. 2017; 130 (7): 908-919. doi:10.1182/blood-2016-12-756767  
24.   Takai-Igarashi Takako, Kinoshita Kengo, Nagasaki Masao, et al. Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design. BMC Medical Informatics and Decision Making. 2017; 17 (1): 100. doi:10.1186/s12911-017-0494-5  
25.   Ishikuro Mami, Matsubara Hiroko, Kikuya Masahiro, et al. Disease prevalence among nursery school children after the Great East Japan earthquake. BMJ Global Health. 2017; 2 (2): e000127. doi:10.1136/bmjgh-2016-000127  
26.   Kikuya Masahiro, Matsubara Hiroko, Ishikuro Mami, et al. Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey. Journal of Epidemiology. 2017; 27 (10): 462-468. doi:10.1016/j.je.2016.09.012  
27.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the health examination survey on early childhood physical growth in the Great East Japan Earthquake affected areas. Journal of Epidemiology. 2017; 27 (3): 135-142. doi:10.1016/j.je.2016.03.001  
28.   Miyashita Masako, Ishikuro Mami, Kikuya Masahiro, et al. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. Journal of Pediatrics and Congenital Disorders. 2017; 4 : . http://www.jpediatrics.com/development-of-a-questionnaire-method-of-screening-for-citrin-deficiency-in-schoolchildren/  
29.   Isojima Tsuyoshi, Yokoya Susumu, Ono Atsushi, et al. Prolonged elevated body mass index in preschool children after the Great East Japan Earthquake. Pediatrics International. 2017; 59 (9): 1002-1009. doi:10.1111/ped.13340  
30.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the Nationwide Nursery School Survey on Child Health Throughout the Great East Japan Earthquake. Journal of Epidemiology. 2016; 26 (2): 98-104. doi:10.2188/jea.JE20150073  
31.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268  
32.   Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463  
33.   Hino-Fukuyo Naomi, Kikuchi Atsuo, Arai-Ichinoi Natsuko, et al. Genomic analysis identifies candidate pathogenic variants in 9 of 18 patients with unexplained West syndrome. Human genetics. 2015; 134 (6): 649-58. doi:10.1007/s00439-015-1553-6  
34.   Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature communications. 2015; 6 : 8018. doi:10.1038/ncomms9018  
35.   Miyashita Masako, Kikuya Masahiro, Yamanaka Chizuru, et al. Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. The Tohoku Journal of Experimental Medicine. 2015; 237 (4): 297-305. doi:10.1620/tjem.237.297  
36.   Kikuya Masahiro, Miyashita Masako, Yamanaka Chizuru, et al. Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2015; 236 (2): 123-130. doi:10.1620/tjem.236.123