Tohoku University Tohoku Medical Megabank Organization (Sadayoshi Ito)

1.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective. International Journal of Epidemiology. 2019; : . doi:10.1093/ije/dyz169  
2.   Kikuchi Koichi, Saigusa Daisuke, Kanemitsu Yoshitomi, et al. Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. Nature Communications. 2019; 10 (1): 1835. doi:10.1038/s41467-019-09735-4  
3.   Nezu Masahiro, Souma Tomokazu, Yu Lei, et al. Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. Kidney International. 2017; 91 (2): 387-401. doi:10.1016/j.kint.2016.08.023  
4.   Nezu Masahiro, Souma Tomokazu, Yu Lei, et al. Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. Science Signaling. 2017; 10 (479): eaam5711. doi:10.1126/scisignal.aam5711  
5.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268  
6.   Sato Emiko, Tsunokuni Yukako, Fushima Tomofumi, et al. OS 08-06 METABOLOMIC ANALYSIS OF A MOUSE MODEL OF PREECLAMPSIA INDUCED BY OVERPRODUCING sFlt-1. Journal of hypertension. 2016; 34 Suppl 1 : e69. doi:10.1097/01.hjh.0000500031.24401.46  
7.   Mishima Eikan, Nishimiya Kensuke, Fujiwara Yasushi, et al. Serious Hypocalcemia After Withdrawal of Vitamin D Analog in Bedridden Nonagenarians with Previous Thyroidectomy: A Report of Two Cases. Journal of the American Geriatrics Society. 2016; 64 (6): 1374-1376. doi:10.1111/jgs.14171  
8.   Li Feng, Fushima Tomofumi, Oyanagi Gen, et al. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proceedings of the National Academy of Sciences. 2016; 113 (47): 13450-13455. doi:10.1073/pnas.1614947113  
9.   Sato Emiko, Mori Takefumi, Mishima Eikan, et al. Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease. Scientific Reports. 2016; 6 (1): 36618. doi:10.1038/srep36618  
10.   Endo Shun, Mishima Eikan, Takeuchi Yoichi, et al. Periodontitis-associated septic pulmonary embolism caused by Actinomyces species identified by anaerobic culture of bronchoalveolar lavage fluid: a case report. BMC Infectious Diseases. 2015; : . doi:10.1186/s12879-015-1286-0  
11.   Mishima Eikan, Fukuda Shinji, Shima Hisato, et al. Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD. Journal of the American Society of Nephrology : JASN. 2015; 26 (8): 1787-94. doi:10.1681/ASN.2014060530  
12.   Takeuchi Yoichi, Mishima Eikan, Shima Hisato, et al. Exonic mutations in the SLC12A3 gene cause exon skipping and premature termination in Gitelman syndrome. Journal of the American Society of Nephrology : JASN. 2015; 26 (2): 271-9. doi:10.1681/ASN.2013091013  
13.   Ito Daisuke, Cao Pengyu, Kakihana Takaaki, et al. Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats. PLOS ONE. 2015; 10 (9): e0138037. doi:10.1371/journal.pone.0138037  
14.   Mishima Eikan, Jinno Daisuke, Akiyama Yasutoshi, et al. Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides. PLOS ONE. 2015; 10 (11): e0143756. doi:10.1371/journal.pone.0143756  
15.   Suzuki Takehiro, Yamaguchi Hiroaki, Kikusato Motoi, et al. Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases. The Tohoku Journal of Experimental Medicine. 2015; 236 (3): 225-232. doi:10.1620/tjem.236.225  
16.   Mishima Eikan, Inoue Chisako, Saigusa Daisuke, et al. Conformational change in transfer RNA is an early indicator of acute cellular damage. Journal of the American Society of Nephrology : JASN. 2014; 25 (10): 2316-26. doi:10.1681/ASN.2013091001  
17.   Konno Satoshi, Hozawa Atsushi, Miura Yukio, et al. High-normal diastolic blood pressure is a risk for development of microalbuminuria in the general population: the Watari study. Journal of hypertension. 2013; 31 (4): 798-804. doi:10.1097/HJH.0b013e32835e2146  
18.   Akiyama Yasutoshi, Takeuchi Yoichi, Kikuchi Koichi, et al. A metabolomic approach to clarifying the effect of AST-120 on 5/6 nephrectomized rats by capillary electrophoresis with mass spectrometry (CE-MS). Toxins. 2012; 4 (11): 1309-22. doi:10.3390/toxins4111309