Tohoku University Tohoku Medical Megabank Organization (Matsuyuki Shirota)
2021.03.05

1.   Tadaka Shu, Hishinuma Eiji, Komaki Shohei, et al. jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population. Nucleic Acids Research. 2021; 49 (D1): D536-D544. doi:10.1093/nar/gkaa1034  
2.   Koshiba Seizo, Motoike Ikuko N., Saigusa Daisuke, et al. Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population. Communications Biology. 2020; 3 (1): 662. doi:10.1038/s42003-020-01383-5  
3.   Shirota Matsuyuki, Saigusa Daisuke, Yamashita Riu, et al. Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy. Medical Mass Spectrometry. 2020; 4 (1): 36-49. doi:10.24508/mms.2020.06.001  
4.   Wada Yoichi, Kikuchi Atsuo, Kaga Akimune, et al. Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice. PLOS Genetics. 2020; 16 (2): e1008628. doi:10.1371/journal.pgen.1008628  
5.   Akiyama Tetsuya, Suzuki Naoki, Ishikawa Mitsuru, et al. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons. EBioMedicine. 2019; 45 : 362-378. doi:10.1016/j.ebiom.2019.06.013  
6.   Tadaka Shu, Katsuoka Fumiki, Ueki Masao, et al. 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. Human Genome Variation. 2019; 6 (1): 28. doi:10.1038/s41439-019-0059-5  
7.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096  
8.   Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588  
9.   Takeuchi Fumihiko, Akiyama Masato, Matoba Nana, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications. 2018; 9 (1): 5052. doi:10.1038/s41467-018-07345-0  
10.   Tadaka Shu, Saigusa Daisuke, Motoike Ikuko N., et al. jMorp: Japanese Multi Omics Reference Panel. Nucleic Acids Research. 2018; 46 (D1): D551-D557. doi:10.1093/nar/gkx978  
11.   Kondo Hiroko X., Yoshida Norio, Shirota Matsuyuki, Kinoshita Kengo. Molecular Mechanism of Depolarization-Dependent Inactivation in W366F Mutant of Kv1.2. The Journal of Physical Chemistry B. 2018; 122 (48): 10825-10833. doi:10.1021/acs.jpcb.8b09446  
12.   Shirota Matsuyuki, Kinoshita Kengo. Discrepancies between human DNA, mRNA and protein reference sequences and their relation to single nucleotide variants in the human population. Database. 2016; 2016 : baw124. doi:10.1093/database/baw124  
13.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Ion Concentration- and Voltage-Dependent Push and Pull Mechanisms of Potassium Channel Ion Conduction. PLOS ONE. 2016; 11 (3): e0150716. doi:10.1371/journal.pone.0150716  
14.   Fujiwara Yuichiro, Kondo Hiroko X., Shirota Matsuyuki, et al. Structural basis for the membrane association of ankyrinG via palmitoylation. Scientific Reports. 2016; 6 (1): 23981. doi:10.1038/srep23981  
15.   Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463  
16.   Motoike Ikuko N, Matsumoto Mitsuyo, Danjoh Inaho, et al. Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population. BMC Genomics. 2014; 15 (1): 673. doi:10.1186/1471-2164-15-673  
17.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Comprehensive Classification and Diversity Assessment of Atomic Contacts in Protein–Small Ligand Interactions. Journal of Chemical Information and Modeling. 2013; 53 (1): 241-248. doi:10.1021/ci300377f  
18.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Ion Concentration-Dependent Ion Conduction Mechanism of a Voltage-Sensitive Potassium Channel. PLoS ONE. 2013; 8 (2): e56342. doi:10.1371/journal.pone.0056342  
19.   Shirota Matsuyuki, Kinoshita Kengo. Analyses of the general rule on residue pair frequencies in local amino acid sequences of soluble, ordered proteins. Protein Science. 2013; 22 (6): 725-733. doi:10.1002/pro.2255