Tohoku University Tohoku Medical Megabank Organization (Masahiro Kikuya)
2022.05.17

1.   Satoh Michihiro, Metoki Hirohito, Asayama Kei, et al. Prediction Models for the 5- and 10-Year Incidence of Home Morning Hypertension: The Ohasama Study. American Journal of Hypertension. 2022; 35 (4): 328-336. doi:10.1093/ajh/hpab177  
2.   Kogure Mana, Nakamura Tomohiro, Tsuchiya Naho, et al. Consideration of the reference value and number of measurements of the urinary sodium-to-potassium ratio based on the prevalence of untreated home hypertension: TMM Cohort Study. Hypertension Research. 2022; : . doi:10.1038/s41440-021-00843-7  
3.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2022; 32 (2): JE20200338. doi:10.2188/jea.JE20200338  
4.   Kikuchi Daisuke, Obara Taku, Usuzaki Takuma, et al. Evaluating folic acid supplementation among Japanese pregnant women with dietary intake of folic acid lower than 480 µg per day: results from TMM BirThree Cohort Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2022; 35 (5): 964-969. doi:10.1080/14767058.2020.1739020  
5.   Ishikuro Mami, Noda Aoii, Murakami Keiko, et al. Families’ Health after the Great East Japan Earthquake: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2022; 256 (2): 93-101. doi:10.1620/tjem.256.93  
6.   Hirata Takumi, Kogure Mana, Tsuchiya Naho, et al. Impacts of the urinary sodium-to-potassium ratio, sleep efficiency, and conventional risk factors on home hypertension in a general Japanese population. Hypertension Research. 2021; 44 (7): 858-865. doi:10.1038/s41440-021-00628-y  
7.   Nakayama Shingo, Satoh Michihiro, Metoki Hirohito, et al. Lifetime risk of stroke stratified by chronic kidney disease and hypertension in the general Asian population: the Ohasama study. Hypertension Research. 2021; 44 (7): 866-873. doi:10.1038/s41440-021-00635-z  
8.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study profile of the tohoku medical megabank community-based cohort study. Journal of Epidemiology. 2021; 31 (1): 65-76. doi:10.2188/jea.JE20190271  
9.   Nishikawa Tomofumi, Akiguchi Ichiro, Satoh Michihiro, et al. The association of disproportionately enlarged subarachnoid space hydrocephalus with cognitive deficit in a general population: the Ohasama study. Scientific Reports. 2021; 11 (1): 17061. doi:10.1038/s41598-021-95961-0  
10.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2020; 16 (2): 295-300. doi:10.1080/21645515.2019.1655833  
11.   Wagata Maiko, Kogure Mana, Nakaya Naoki, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertension Research. 2020; 43 (11): 1277-1283. doi:10.1038/s41440-020-0463-8  
12.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2  
13.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0  
14.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169  
15.   Usuzaki Takuma, Ishikuro Mami, Metoki Hirohito, et al. Comparison among research, home, and office blood pressure measurements for pregnant women: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2020; 22 (11): 2004-2013. doi:10.1111/jch.14050  
16.   Fujita Ayami, Hara Azusa, Kikuya Masahiro, et al. Blood Pressure Phenotypes Defined by Ambulatory Blood Pressure Monitoring and Carotid Artery Changes in Community-Dwelling Older Japanese Adults: The Ohasama Study. The Tohoku Journal of Experimental Medicine. 2020; 252 (3): 269-279. doi:10.1620/tjem.252.269  
17.   Tsuboi Akito, Matsui Hiroyuki, Shiraishi Naru, et al. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 251 (2): 97-115. doi:10.1620/tjem.251.97  
18.   Narita Akira, Nagai Masato, Mizuno Satoshi, et al. Clustering by phenotype and genome-wide association study in autism. Translational Psychiatry. 2020; 10 (1): 290. doi:10.1038/s41398-020-00951-x  
19.   Isojima Tsuyoshi, Kato Noriko, Yokoya Susumu, et al. Early excessive growth with distinct seasonality in preschool obesity. Archives of Disease in Childhood. 2019; 104 (1): 53-57. doi:10.1136/archdischild-2018-314862  
20.   Kuniyoshi Yasutaka, Kikuya Masahiro, Matsubara Hiroko, et al. Association of Feeding Practice with Childhood Overweight and/or Obesity in Affected Areas Before and After the Great East Japan Earthquake. Breastfeeding Medicine. 2019; 14 (6): 382-389. doi:10.1089/bfm.2018.0254  
21.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Disaster Medicine and Public Health Preparedness. 2019; 13 (5-6): 905-911. doi:10.1017/dmp.2019.8  
22.   Satoh Michihiro, Metoki Hirohito, Asayama Kei, et al. Age‐Related Trends in Home Blood Pressure, Home Pulse Rate, and Day‐to‐Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study. Journal of the American Heart Association. 2019; 8 (15): e012121. doi:10.1161/JAHA.119.012121  
23.   Sakama Reiko, Yokokawa Hirohide, Fujibayashi Kazutoshi, et al. Psychological Characteristics of Children at Two Years after the Great East Japan Earthquake: Analyses of Telephone Consultation Records. The Tohoku Journal of Experimental Medicine. 2019; 249 (2): 85-92. doi:10.1620/tjem.249.85  
24.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. Allergology International. 2018; 67 (4): 481-486. doi:10.1016/j.alit.2018.02.009  
25.   Imai Yutaka, Asayama Kei, Fujiwara Seisuke, et al. Development and evaluation of a home nocturnal blood pressure monitoring system using a wrist-cuff device. Blood Pressure Monitoring. 2018; 23 (6): 318-326. doi:10.1097/MBP.0000000000000351  
26.   Saito Sho, Ohi Takashi, Murakami Takahisa, et al. Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study. BMC Oral Health. 2018; 18 (1): 142. doi:10.1186/s12903-018-0602-7  
27.   Ono Atsushi, Isojima Tsuyoshi, Yokoya Susumu, et al. Effect of the Fukushima earthquake on weight in early childhood: a retrospective analysis. BMJ Paediatrics Open. 2018; 2 (1): e000229. doi:10.1136/bmjpo-2017-000229  
28.   Satoh Michihiro, Murakami Takahisa, Asayama Kei, et al. N-Terminal Pro-B-Type Natriuretic Peptide Is Not a Significant Predictor of Stroke Incidence After 5 Years ― The Ohasama Study ―. Circulation Journal. 2018; 82 (8): 2055-2062. doi:10.1253/circj.CJ-17-1227  
29.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Nocturnal blood pressure decline based on different time intervals and long-term cardiovascular risk: the Ohasama Study. Clinical and Experimental Hypertension. 2018; 40 (1): 1-7. doi:10.1080/10641963.2016.1259324  
30.   Watabe Daisuke, Asayama Kei, Hanazawa Tomohiro, et al. Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study. Hypertension Research. 2018; 41 (8): 622-628. doi:10.1038/s41440-018-0050-4  
31.   Kato N, Isojima T, Yokoya S, et al. Earlier BMI rebound and lower pre-rebound BMI as risk of obesity among Japanese preschool children. International Journal of Obesity. 2018; 42 (1): 52-58. doi:10.1038/ijo.2017.242  
32.   Yokomichi Hiroshi, Matsubara Hiroko, Ishikuro Mami, et al. Impact of the Great East Japan Earthquake on Body Mass Index, Weight, and Height of Infants and Toddlers: An Infant Survey. Journal of Epidemiology. 2018; 28 (5): 237-244. doi:10.2188/jea.JE20170006  
33.   Ohseto Hisashi, Ishikuro Mami, Kikuya Masahiro, et al. Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study. Journal of Psychosomatic Research. 2018; 107 : 20-25. doi:10.1016/j.jpsychores.2018.01.013  
34.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Association Between Amplitude of Seasonal Variation in Self‐Measured Home Blood Pressure and Cardiovascular Outcomes: HOMED‐BP (Hypertension Objective Treatment Based on Measurement By Electrical Devices of Blood Pressure) Study. Journal of the American Heart Association. 2018; 7 (10): . doi:10.1161/JAHA.117.008509  
35.   Obara Taku, Ishikuro Mami, Tamiya Gen, et al. Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports. 2018; 8 (1): 14840. doi:10.1038/s41598-018-33110-w  
36.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Refractive error is associated with intracranial volume. Scientific Reports. 2018; 8 (1): 175. doi:10.1038/s41598-017-18669-0  
37.   Ishikuro Mami, Obara Taku, Osanai Tamae, et al. Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2018; 246 (2): 97-105. doi:10.1620/tjem.246.97  
38.   Ishikuro Mami, Matsubara Hiroko, Kikuya Masahiro, et al. Disease prevalence among nursery school children after the Great East Japan earthquake. BMJ Global Health. 2017; 2 (2): e000127. doi:10.1136/bmjgh-2016-000127  
39.   Igarashi Yuko, Obara Taku, Ishikuro Mami, et al. Randomized controlled trial of the effects of consumption of ‘Yabukita’ or ‘Benifuuki’ encapsulated tea-powder on low-density lipoprotein cholesterol level and body weight. Food & Nutrition Research. 2017; 61 (1): 1334484. doi:10.1080/16546628.2017.1334484  
40.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Seasonal variation in self-measured home blood pressure among patients on antihypertensive medications: HOMED-BP study. Hypertension Research. 2017; 40 (3): 284-290. doi:10.1038/hr.2016.133  
41.   Zheng W, Yokomichi H, Matsubara H, et al. Longitudinal changes in body mass index of children affected by the Great East Japan Earthquake. International Journal of Obesity. 2017; 41 (4): 606-612. doi:10.1038/ijo.2017.6  
42.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Risk Factors for Stroke among Young-Old and Old-Old Community-Dwelling Adults in Japan: The Ohasama Study. Journal of Atherosclerosis and Thrombosis. 2017; 24 (3): 290-300. doi:10.5551/jat.35766  
43.   Kikuya Masahiro, Matsubara Hiroko, Ishikuro Mami, et al. Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey. Journal of Epidemiology. 2017; 27 (10): 462-468. doi:10.1016/j.je.2016.09.012  
44.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the health examination survey on early childhood physical growth in the Great East Japan Earthquake affected areas. Journal of Epidemiology. 2017; 27 (3): 135-142. doi:10.1016/j.je.2016.03.001  
45.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Home blood pressure predicts stroke incidence among older adults with impaired physical function. Journal of Hypertension. 2017; 35 (12): 2395-2401. doi:10.1097/HJH.0000000000001473  
46.   Tsubota-Utsugi Megumi, Satoh Michihiro, Tomita Naoki, et al. Lacunar Infarcts Rather than White Matter Hyperintensity as a Predictor of Future Higher Level Functional Decline: The Ohasama Study. Journal of Stroke and Cerebrovascular Diseases. 2017; 26 (2): 376-384. doi:10.1016/j.jstrokecerebrovasdis.2016.09.036  
47.   Kikuya Masahiro. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. JPCD. 2017; 4 : 1-4. doi:10.17303/jpcd.2017.4.101  
48.   Isojima Tsuyoshi, Yokoya Susumu, Ono Atsushi, et al. Prolonged elevated body mass index in preschool children after the Great East Japan Earthquake. Pediatrics International. 2017; 59 (9): 1002-1009. doi:10.1111/ped.13340  
49.   Takeuchi Fumihiko, Katsuya Tomohiro, Kimura Ryosuke, et al. The fine-scale genetic structure and evolution of the Japanese population. PLOS ONE. 2017; 12 (11): e0185487. doi:10.1371/journal.pone.0185487  
50.   Yokomichi Hiroshi, Zheng Wei, Matsubara Hiroko, et al. Impact of the great east Japan earthquake on the body mass index of preschool children: a nationwide nursery school survey. BMJ Open. 2016; 6 (4): e010978. doi:10.1136/bmjopen-2015-010978  
51.   Ishikuro Mami, Ubeda Sergio Ramón Gutiérrez, Obara Taku, et al. Knowledge, Attitude, and Practices Toward Blood Pressure Measurement at Home Among Japanese Nurses. Home Healthcare Now. 2016; 34 (4): 210-217. doi:10.1097/NHH.0000000000000357  
52.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Long-Term Stroke Risk Due to Partial White-Coat or Masked Hypertension Based on Home and Ambulatory Blood Pressure Measurements. Hypertension. 2016; 67 (1): 48-55. doi:10.1161/HYPERTENSIONAHA.115.06461  
53.   Ishikura Kazuki, Obara Taku, Kikuya Masahiro, et al. Home blood pressure level and decline in renal function among treated hypertensive patients: the J-HOME-Morning Study. Hypertension Research. 2016; 39 (2): 107-112. doi:10.1038/hr.2015.110  
54.   Iwama Noriyuki, Metoki Hirohito, Ohkubo Takayoshi, et al. Maternal clinic and home blood pressure measurements during pregnancy and infant birth weight: the BOSHI study. Hypertension Research. 2016; 39 (3): 151-157. doi:10.1038/hr.2015.108  
55.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the Nationwide Nursery School Survey on Child Health Throughout the Great East Japan Earthquake. Journal of Epidemiology. 2016; 26 (2): 98-104. doi:10.2188/jea.JE20150073  
56.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268  
57.   Satoh Michihiro, Haga Toshikazu, Hosaka Miki, et al. The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements. Journal of Hypertension. 2016; 34 (6): 1218-1223. doi:10.1097/HJH.0000000000000902  
58.   Murakami Keiko, Metoki Hirohito, Satoh Michihiro, et al. Menstrual Factors and Stroke Incidence in Japanese Postmenopausal Women: The Ohasama Study. Neuroepidemiology. 2016; 47 (2): 109-116. doi:10.1159/000452220  
59.   Ishikuro Mami, Nakaya Naoki, Obara Taku, et al. Public Attitudes toward an Epidemiological Study with Genomic Analysis in the Great East Japan Earthquake Disaster Area. Prehospital and Disaster Medicine. 2016; 31 (3): 330-334. doi:10.1017/S1049023X16000182  
60.   Murakami Keiko, Tsubota-Utsugi Megumi, Satoh Michihiro, et al. Impaired Higher-Level Functional Capacity as a Predictor of Stroke in Community-Dwelling Older Adults. Stroke. 2016; 47 (2): 323-328. doi:10.1161/STROKEAHA.115.011131  
61.   Satoh Michihiro, Obara Taku, Nishigori Hidekazu, et al. Prescription trends in children with pervasive developmental disorders: a claims data-based study in Japan. World Journal of Pediatrics. 2016; 12 (4): 443-449. doi:10.1007/s12519-016-0036-8  
62.   Satoh Michihiro, Kikuya Masahiro, Hosaka Miki, et al. Association of Aldosterone-to-Renin Ratio With Hypertension Differs by Sodium Intake: The Ohasama Study. American Journal of Hypertension. 2015; 28 (2): 208-215. doi:10.1093/ajh/hpu115  
63.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Parity as a factor affecting the white-coat effect in pregnant women: the BOSHI study. Hypertension Research. 2015; 38 (11): 770-775. doi:10.1038/hr.2015.97  
64.   Hosaka Miki, Metoki Hirohito, Satoh Michihiro, et al. Randomized trial comparing the velocities of the antihypertensive effects on home blood pressure of candesartan and candesartan with hydrochlorothiazide. Hypertension Research. 2015; 38 (10): 701-707. doi:10.1038/hr.2015.64  
65.   Hosaka Miki, Asayama Kei, Staessen Jan A, et al. Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development. Hypertension Research. 2015; 38 (11): 776-782. doi:10.1038/hr.2015.63  
66.   Satoh Michihiro, Hosaka Miki, Asayama Kei, et al. Association between N-terminal pro B-type natriuretic peptide and day-to-day blood pressure and heart rate variability in a general population. Journal of Hypertension. 2015; 33 (8): 1536-1541. doi:10.1097/HJH.0000000000000570  
67.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Differences between clinic and home blood pressure measurements during pregnancy. Journal of Hypertension. 2015; 33 (7): 1492-1493. doi:10.1097/HJH.0000000000000608  
68.   Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature Communications. 2015; 6 (1): 8018. doi:10.1038/ncomms9018  
69.   Tsubota-Utsugi Megumi, Kikuya M., Satoh M., et al. Living situations associated with poor dietary intake among healthy japanese elderly: The ohasama study. The journal of nutrition, health & aging. 2015; 19 (4): 375-382. doi:10.1007/s12603-015-0456-5  
70.   Miyashita Masako, Kikuya Masahiro, Yamanaka Chizuru, et al. Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. The Tohoku Journal of Experimental Medicine. 2015; 237 (4): 297-305. doi:10.1620/tjem.237.297  
71.   Kikuya Masahiro, Miyashita Masako, Yamanaka Chizuru, et al. Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2015; 236 (2): 123-130. doi:10.1620/tjem.236.123  
72.   Matsumoto Akihiro, Satoh Michihiro, Kikuya Masahiro, et al. Day-to-Day Variability in Home Blood Pressure Is Associated With Cognitive Decline. Hypertension. 2014; 63 (6): 1333-1338. doi:10.1161/HYPERTENSIONAHA.113.01819  
73.   Aparicio Lucas S, Thijs Lutgarde, Asayama Kei, et al. Reference frame for home pulse pressure based on cardiovascular risk in 6470 subjects from 5 populations. Hypertension Research. 2014; 37 (7): 672-678. doi:10.1038/hr.2014.45  
74.   Imai Eri, Tsubota-Utsugi Megumi, Kikuya Masahiro, et al. Animal Protein Intake Is Associated with Higher-Level Functional Capacity in Elderly Adults: The Ohasama Study. Journal of the American Geriatrics Society. 2014; 62 (3): 426-434. doi:10.1111/jgs.12690  
75.   Asayama Kei, Thijs Lutgarde, Brguljan-Hitij Jana, et al. Risk Stratification by Self-Measured Home Blood Pressure across Categories of Conventional Blood Pressure: A Participant-Level Meta-Analysis. PLoS Medicine. 2014; 11 (1): e1001591. doi:10.1371/journal.pmed.1001591  
76.   Tsubota-Utsugi Megumi, Satoh Michihiro, Hosaka Miki, et al. Personality Traits as Predictors of Decline in Higher-Level Functional Capacity over a 7-Year Follow-Up in Older Adults: The Ohasama Study. The Tohoku Journal of Experimental Medicine. 2014; 234 (3): 197-207. doi:10.1620/tjem.234.197  
77.   Obara Taku, Kikuya Masahiro, Kobayashi Yuka, et al. Associations Between Visit-to-visit Variability in Blood Pressure Measured in the Office and Antihypertensive Drugs: The J-HOME-Morning Study. Clinical and Experimental Hypertension. 2013; 35 (4): 285-290. doi:10.3109/10641963.2013.780070  
78.   Kanno Atsuhiro, Kikuya Masahiro, Asayama Kei, et al. Night-time blood pressure is associated with the development of chronic kidney disease in a general population. Journal of Hypertension. 2013; 31 (12): 2410-2417. doi:10.1097/HJH.0b013e328364dd0f