Tohoku University Tohoku Medical Megabank Organization (Kumi Nakaya)
2025.02.14

1.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Association Between Sodium- and Potassium-Related Urinary Markers and the Prevalence of Atrial Fibrillation. Circulation Journal. 2025; : CJ-24-0780. doi:10.1253/circj.CJ-24-0780  
2.   Kiuchi Sakura, Nakaya Kumi, Cooray Upul, et al. A Principal Component Analysis of Metabolome and Cognitive Decline Among Japanese Older Adults: Cross-sectional Analysis Using Tohoku Medical Megabank Cohort Study Data. Journal of Epidemiology. 2025; 35 (1): JE20240099. doi:10.2188/jea.JE20240099  
3.   Nakaya Naoki, Nakaya Kumi, Kogure Mana, et al. Degree of housing damage caused by the Great East Japan Earthquake and all-cause mortality in the community-based cohort study of the Tohoku Medical Megabank Project. Journal of Epidemiology and Community Health. 2025; : jech-2024-223084. doi:10.1136/jech-2024-223084  
4.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Effect of Social Support on Caregiver's Functional Disability Due to Spouse's Functional Disability. Journal of the American Medical Directors Association. 2025; 26 (1): 105324. doi:10.1016/j.jamda.2024.105324  
5.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between leisure time, non-leisure time physical activity, and kidney function in Japanese adults: a cross-sectional study. BMC Nephrology. 2024; 25 (1): 354. doi:10.1186/s12882-024-03813-6  
6.   Noji Yoshiaki, Hatanaka Rieko, Nakaya Naoki, et al. Association of physiological factors with grip and leg extension strength: tohoku medical megabank community-based cohort study. BMC Public Health. 2024; 24 (1): 714. doi:10.1186/s12889-024-18244-z  
7.   Akaishi Tetsuya, Nakaya Kumi, Nakaya Naoki, et al. Low Hemoglobin Level and Elevated Inflammatory Hematological Ratios Associated With Depression and Sleep Disturbance. Cureus. 2024; : . doi:10.7759/cureus.56621  
8.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between housing and psychological damage by earthquake and modifiable risk factors for dementia in general older adults: Tohoku Medical Megabank community‐based cohort study. Geriatrics & Gerontology International. 2024; 24 (6): 509-516. doi:10.1111/ggi.14867  
9.   Takase Masato, Hirata Takumi, Nakaya Naoki, et al. Associations of combined genetic and lifestyle risks with hypertension and home hypertension. Hypertension Research. 2024; 47 (8): 2064-2074. doi:10.1038/s41440-024-01705-8  
10.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Depressive symptoms as risk factors for the onset of home hypertension: a prospective cohort study. Hypertension Research. 2024; 47 (11): 2989-3000. doi:10.1038/s41440-024-01790-9  
11.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study. Hypertension Research. 2024; 47 (6): 1533-1545. doi:10.1038/s41440-024-01582-1  
12.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center. Hypertension Research. 2024; 47 (3): 586-597. doi:10.1038/s41440-023-01484-8  
13.   Himuro Hiromi, Kogure Mana, Nakaya Naoki, et al. The association of birth weight and current BMI on the risk of hypertension: the Tohoku medical megabank community-based cohort study. Hypertension Research. 2024; 47 (11): 3025-3034. doi:10.1038/s41440-024-01827-z  
14.   Yamada Mitsuhiro, Takase Masato, Nakaya Kumi, et al. Fractional exhaled nitric oxide distribution and its relevant factors in the general adult population and its healthy subpopulation. Journal of Allergy and Clinical Immunology: Global. 2024; 3 (3): 100253. doi:10.1016/j.jacig.2024.100253  
15.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Genetic Risk, Healthy Lifestyle Adherence, and Risk of Developing Diabetes in the Japanese Population. Journal of Atherosclerosis and Thrombosis. 2024; 31 (12): 64906. doi:10.5551/jat.64906  
16.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2024; 31 (6): 64535. doi:10.5551/jat.64535  
17.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Combined Fat Mass and Fat-free Mass Indices and Lung Function Among Japanese Population: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2024; 34 (3): JE20220355. doi:10.2188/jea.JE20220355  
18.   Hozawa Atsushi, Nakaya Kumi, Nakaya Naoki, et al. Progress Report of the Tohoku Medical Megabank Community-based Cohort Study: Study Profile of the Repeated Center-based Survey During Second Period in Miyagi Prefecture. Journal of Epidemiology. 2024; 34 (9): JE20230241. doi:10.2188/jea.JE20230241  
19.   Nakaya Kumi, Nakaya Naoki, Kogure Mana, et al. Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study. Journal of Neurogastroenterology and Motility. 2024; 30 (2): 208-219. doi:10.5056/jnm23090  
20.   Orui Masatsugu, Obara Taku, Ishikuro Mami, et al. Evaluation of depression at 6 and 12 months postpartum by examining depressive symptoms and self‐harm ideation during the early postpartum period: Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Psychiatry and Clinical Neurosciences Reports. 2024; 3 (4): . doi:10.1002/pcn5.70025  
21.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Genetic Risk, Lifestyle Adherence, and Risk of Developing Hyperuricaemia in a Japanese Population. Rheumatology. 2024; : . doi:10.1093/rheumatology/keae492  
22.   Sato Shuichi, Imaeda Takao, Mugikura Shunji, et al. Association of olfactory and cognitive function test scores with hippocampal and amygdalar grey matter volume: a cross-sectional study. Scientific Reports. 2024; 14 (1): 19138. doi:10.1038/s41598-024-69726-4  
23.   Gearry Richard, Fukudo Shin, Barbara Giovanni, et al. Consumption of 2 Green Kiwifruits Daily Improves Constipation and Abdominal Comfort—Results of an International Multicenter Randomized Controlled Trial. American Journal of Gastroenterology. 2023; 118 (6): 1058-1068. doi:10.14309/ajg.0000000000002124  
24.   Hasegawa Ryoko, Saito-Nakaya Kumi, Gu Li, et al. Maternal separation and TNBS-induced gut inflammation synergistically alter the sexually differentiated stress response in rats. BioPsychoSocial Medicine. 2023; 17 (1): 7. doi:10.1186/s13030-022-00258-x  
25.   Ishikawa Hirono, Ogawa Runa, Otsuki Aki, et al. Effect modification by geographic area on the association between health literacy and self-rated health: a nationwide cross-sectional study in Japan. BMC Public Health. 2023; 23 (1): 952. doi:10.1186/s12889-023-15897-0  
26.   Hatanaka Rieko, Nakaya Naoki, Kogure Mana, et al. The risk of withdrawal from hypertension treatment in coastal areas after the Great East Japan Earthquake: the TMM CommCohort Study. Hypertension Research. 2023; 46 (12): 2718-2728. doi:10.1038/s41440-023-01454-0  
27.   Sato Shuichi, Imaeda Takao, Mugikura Shunji, et al. Association Between Olfactory Test Data with Multiple Levels of Odor Intensity and Suspected Cognitive Impairment: A Cross-Sectional Study. Journal of Alzheimer's Disease. 2023; 95 (4): 1469-1480. doi:10.3233/JAD-230318  
28.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. Association of Central Blood Pressure and Carotid Intima Media Thickness with New-Onset Hypertension in People with High Normal Blood Pressure. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64151. doi:10.5551/jat.64151  
29.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (3): 63523. doi:10.5551/jat.63523  
30.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (10): 64039. doi:10.5551/jat.64039  
31.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64425. doi:10.5551/jat.64425  
32.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. The Association of Lung Function and Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (8): 63826. doi:10.5551/jat.63826  
33.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Hypertension. 2023; 41 (3): 443-452. doi:10.1097/HJH.0000000000003356  
34.   Mitsutake Seigo, Takahashi Yoshimitsu, Otsuki Aki, et al. Chronic Diseases and Sociodemographic Characteristics Associated With Online Health Information Seeking and Using Social Networking Sites: Nationally Representative Cross-sectional Survey in Japan. Journal of Medical Internet Research. 2023; 25 : e44741. doi:10.2196/44741  
35.   Akaishi Tetsuya, Misu Tatsuro, Fujihara Kazuo, et al. White blood cell count profiles in anti-aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder and anti-myelin oligodendrocyte glycoprotein antibody-associated disease. Scientific Reports. 2023; 13 (1): 6481. doi:10.1038/s41598-023-33827-3  
36.   Nakaya Naoki, Nakaya Kumi, Tsuchiya Naho, et al. Similarities in cardiometabolic risk factors among random male-female pairs: a large observational study in Japan. BMC Public Health. 2022; 22 (1): 1978. doi:10.1186/s12889-022-14348-6  
37.   髙瀬 雅仁, 五十嵐 有香, 中谷 直樹, et al. 東日本大震災に伴う災害による健康影響に関する文献レビュー. 日本循環器病予防学会誌. 2021; 56 (3): 244-257.  
38.   Nakaya Naoki, Sone Toshimasa, Tomata Yasutake, et al. All-cause mortality among Japanese whose cohabiting partners are diagnosed with cancer: the Ohsaki Cohort 2006 study. Acta Oncologica. 2019; 58 (4): 425-431. doi:10.1080/0284186X.2018.1562208  
39.   Sone Toshimasa, Nakaya Naoki, Tomata Yasutake, et al. Spouse's functional disability and mortality: The Ohsaki Cohort 2006 Study. Geriatrics & Gerontology International. 2019; 19 (8): 774-779. doi:10.1111/ggi.13709  
40.   Nishi Daisuke, Su Kuan-Pin, Usuda Kentaro, et al. The Efficacy of Omega-3 Fatty Acids for Depressive Symptoms among Pregnant Women in Japan and Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial (SYNCHRO; NCT01948596). Psychotherapy and Psychosomatics. 2019; 88 (2): 122-124. doi:10.1159/000495296  
41.   Oba Akira, Nakaya Naoki, Saito-Nakaya Kumi, et al. Psychological distress in men with prostate cancer and their partners before and after cancer diagnosis: a longitudinal study. Japanese Journal of Clinical Oncology. 2017; 47 (8): 735-742. doi:10.1093/jjco/hyx066  
42.   Nakaya Naoki, Sone Toshimasa, Nakaya Kumi, et al. Psychological Distress among Individuals Whose Partners Have Cancer. The Tohoku Journal of Experimental Medicine. 2017; 243 (1): 27-33. doi:10.1620/tjem.243.27  
43.   Shimizu Ken, Nakaya Naoki, Saito-Nakaya Kumi, et al. Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors. Japanese Journal of Clinical Oncology. 2015; 45 (5): 456-463. doi:10.1093/jjco/hyv024  
44.   Nakaya N., Kogure M., Saito-Nakaya K., et al. The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study. The European Journal of Public Health. 2014; 24 (1): 45-49. doi:10.1093/eurpub/ckt017  
45.   Nakaya Naoki, Saito-Nakaya Kumi, Bidstrup Pernille E., et al. All-Cause Mortality Among Men Whose Cohabiting Partner Has Been Diagnosed with Cancer. Epidemiology. 2013; 24 (1): 96-99. doi:10.1097/EDE.0b013e318276cced