Tohoku University Tohoku Medical Megabank Organization (Ikuo Hirano)
2024.04.23

1.   Shimizu Ritsuko, Hirano Ikuo, Hasegawa Atsushi, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Communications Biology. 2023; 6 (1): 875. doi:10.1038/s42003-023-05251-w  
2.   Nakai Taku, Saigusa Daisuke, Iwamura Yuma, et al. Esterification promotes the intracellular accumulation of roxadustat, an activator of hypoxia-inducible factors, to extend its effective duration. Biochemical Pharmacology. 2022; 197 : 114939. doi:10.1016/j.bcp.2022.114939  
3.   Yamaguchi Ayami, Hirano Ikuo, Narusawa Shiho, et al. Blockade of the interaction between BMP9 and endoglin on erythroid progenitors promotes erythropoiesis in mice. Genes to Cells. 2021; 26 (10): 782-797. doi:10.1111/gtc.12887  
4.   Suzuki Takafumi, Uruno Akira, Yumoto Akane, et al. Nrf2 contributes to the weight gain of mice during space travel. Communications Biology. 2020; 3 (1): 496. doi:10.1038/s42003-020-01227-2