Tohoku University Tohoku Medical Megabank Organization (Hafumi Nishi)
2026.01.21

1.   Kawada Sakiya, Kurumida Yoichi, Ito Tomoyuki, et al. Discovery and affinity maturation of antibody fragments from an unfavorably enriched phage display selection by deep sequencing and machine learning. Journal of Bioscience and Bioengineering. 2025; 140 (2): 51-58. doi:10.1016/j.jbiosc.2025.05.004  
2.   Nakane Keita, Fujimura Chizu, Miyano Shogo, et al. Laccase-catalyzed tyrosine click reaction with 1-methyl-4-arylurazole: rapid labeling on protein surfaces. Chemical Communications. 2024; 60 (96): 14208-14211. doi:10.1039/D4CC03802A  
3.   Hirose Wataru, Horiuchi Makoto, Li Donghan, et al. Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium. Cellular and Molecular Gastroenterology and Hepatology. 2023; 15 (1): 153-178. doi:10.1016/j.jcmgh.2022.09.004  
4.   Zhang Lin, Nishi Hafumi, Kinoshita Kengo. Single-cell RNA-seq public data reveal the gene regulatory network landscape of respiratory epithelial and peripheral immune cells in COVID-19 patients. Frontiers in Immunology. 2023; 14 : . doi:10.3389/fimmu.2023.1194614  
5.   Ito Tomoyuki, Nguyen Thuy Duong, Saito Yutaka, et al. Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning. mAbs. 2023; 15 (1): . doi:10.1080/19420862.2023.2168470  
6.   Zhang Lin, Nishi Hafumi. Transcriptome analysis of Homo sapiens and Mus musculus reveals mechanisms of CD8+ T cell exhaustion caused by different factors. PLOS ONE. 2022; 17 (9): e0274494. doi:10.1371/journal.pone.0274494