| 1. |
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Kawaguchi Chikana, Ozawa Maki, Hidaka Takanori, et al. Skin health survey on atopic dermatitis among Japanese children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Allergology International. 2025; 74 (2): 246-253. doi:10.1016/j.alit.2024.09.008 |
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| 2. |
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Ishikuro Mami, Obara Taku, Hasegawa Mayu, et al. Subsequent high blood pressure and hypertension by hypertensive disorders of pregnancy: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Hypertension Research. 2025; 48 (1): 68-76. doi:10.1038/s41440-024-01936-9 |
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| 3. |
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Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Exploring the association between human breast milk lipids and early adiposity rebound in children: A case-control study. Nutrition. 2025; 135 : 112739. doi:10.1016/j.nut.2025.112739 |
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| 4. |
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Nakatochi Masahiro, Kushima Itaru, Aleksic Branko, et al. Copy number variations in RNF216 and postsynaptic membrane–associated genes are associated with bipolar disorder: a case‐control study in the Japanese population. Psychiatry and Clinical Neurosciences. 2025; 79 (1): 12-20. doi:10.1111/pcn.13752 |
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| 5. |
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Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Association Between Human Milk Oligosaccharides and Early Adiposity Rebound in Children: A Case–Control Study of the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Journal of Nutrition. 2025; : . doi:10.1016/j.tjnut.2025.02.024 |
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| 6. |
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Shinoda Genki, Matsuzaki Fumiko, Ueno Fumihiko, et al. Impact of Telework on Health and Lifestyle Changes During the COVID-19 Pandemic in Japan. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J014. doi:10.1620/tjem.2025.J014 |
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| 7. |
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Yonezawa Yudai, Takahashi Ippei, Ohseto Hisashi, et al. Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2024; 24 (1): 209. doi:10.1186/s12884-024-06376-4 |
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| 8. |
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Noda Aoi, Obara Taku, Matsuzaki Fumiko, et al. Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy. Drugs - Real World Outcomes. 2024; 11 (2): 263-272. doi:10.1007/s40801-023-00411-0 |
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| 9. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal social isolation and behavioral problems in preschool children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Child & Adolescent Psychiatry. 2024; 33 (3): 761-769. doi:10.1007/s00787-023-02199-4 |
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| 10. |
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Noda Aoi, Obara Taku, Shirota Matsuyuki, et al. Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Pharmacology. 2024; 80 (8): 1171-1180. doi:10.1007/s00228-024-03685-7 |
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| 11. |
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Takahashi Ippei, Ohseto Hisashi, Ueno Fumihiko, et al. Genome-wide association study based on clustering by obesity-related variables uncovers a genetic architecture of obesity in the Japanese and the UK populations. Heliyon. 2024; 10 (16): e36023. doi:10.1016/j.heliyon.2024.e36023 |
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| 12. |
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Ishikuro Mami, Obara Taku, Murakami Keiko, et al. The association between blood pressure control in women during pregnancy and adverse perinatal outcomes: the TMM BirThree Cohort Study. Hypertension Research. 2024; 47 (5): 1216-1222. doi:10.1038/s41440-023-01570-x |
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| 13. |
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Nakadate Misako, Kobayashi Shunichiro, Ishihara Junko, et al. Validity of a Web-Based 24-Hour Dietary Recall of Energy and Nutrient Intakes in Japanese Adults. Nutrients. 2024; 16 (23): 4140. doi:10.3390/nu16234140 |
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| 14. |
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Noda Aoi, Arita Ryutaro, Obara Taku, et al. The Use of Japanese Traditional (Kampo) Medicines Before and During Pregnancy in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Pharmacoepidemiology and Drug Safety. 2024; 33 (10): . doi:10.1002/pds.70033 |
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| 15. |
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Li Xue, Takahashi Nagahide, Narita Akira, et al. Identification of risk loci for postpartum depression in a genome‐wide association study. Psychiatry and Clinical Neurosciences. 2024; 78 (11): 712-720. doi:10.1111/pcn.13731 |
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| 16. |
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Takahashi Ippei, Obara Taku, Kikuchi Saya, et al. Combination of taking neuropsychiatric medications and psychological distress in pregnant women, with behavioral problems in children at 2 years of age: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Psychiatry and Clinical Neurosciences Reports. 2024; 3 (3): . doi:10.1002/pcn5.226 |
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| 17. |
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Usuzaki Takuma, Ishikuro Mami, Kikuya Masahiro, et al. Child-parent associations of hematocrit in trios of Japanese adulthood confirmed by the random family method: The TMM BirThree Cohort Study. Scientific Reports. 2024; 14 (1): 19047. doi:10.1038/s41598-024-69752-2 |
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| 18. |
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Machida Toshiya, Obara Taku, Ishikuro Mami, et al. Liver steatosis and fibrosis markers’ association with cardiovascular and renal damage in Japanese adults: the TMM BirThree cohort study. Annals of Hepatology. 2023; 28 (1): 100761. doi:10.1016/j.aohep.2022.100761 |
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| 19. |
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Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal postnatal bonding disorder and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2023; 26 (2): 219-226. doi:10.1007/s00737-023-01298-0 |
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| 20. |
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Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and infant birth weight: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Pregnancy and Childbirth. 2023; 23 (1): 268. doi:10.1186/s12884-023-05603-8 |
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| 21. |
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Shinoda Genki, Nagaoka Yudai, Ueno Fumihiko, et al. Association between being Overweight in Young Childhood and during School Age and Puberty. Children. 2023; 10 (5): 909. doi:10.3390/children10050909 |
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| 22. |
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Ueno Fumihiko, Murakami Keiko, Nagai Masato, et al. Difficulties in Accessing Medication Records at the Time of a Large-Scale Disaster. Disaster Medicine and Public Health Preparedness. 2023; 17 : e370. doi:10.1017/dmp.2022.301 |
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| 23. |
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Obara Taku, Ishikuro Mami, Ueno Fumihiko, et al. Antihypertensive drug use during pregnancy in Japan. Hypertension Research. 2023; 46 (2): 548-549. doi:10.1038/s41440-022-01101-0 |
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| 24. |
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Takahashi Ippei, Obara Taku, Ishikuro Mami, et al. Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years. JAMA Pediatrics. 2023; 177 (10): 1039. doi:10.1001/jamapediatrics.2023.3057 |
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| 25. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal postnatal bonding disorder and emotional/behavioral problems in preschool children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 325 : 582-587. doi:10.1016/j.jad.2023.01.044 |
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| 26. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Traumatic experiences of the Great East Japan Earthquake and postpartum depressive symptoms: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 320 : 461-467. doi:10.1016/j.jad.2022.09.139 |
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| 27. |
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Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Factors Associated With Postpartum Smoking Relapse Among Women Who Quit in Early Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (1): JE20200609. doi:10.2188/jea.JE20200609 |
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| 28. |
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Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Relation of Disaster Exposure With Maternal Characteristics and Obstetric Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (3): JE20210052. doi:10.2188/jea.JE20210052 |
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| 29. |
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Takahashi Ippei, Obara Taku, Kikuchi Saya, et al. Association between maternal psychological distress and children's neurodevelopment in offspring aged 4 years in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Journal of Paediatrics and Child Health. 2023; 59 (3): 548-554. doi:10.1111/jpc.16353 |
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| 30. |
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Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of Education and Income with Secondhand Smoke Exposure Among Non-smoking Pregnant Women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Maternal and Child Health Journal. 2023; 27 (7): 1238-1246. doi:10.1007/s10995-023-03648-x |
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| 31. |
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Aizawa Misato, Murakami Keiko, Yonezawa Yudai, et al. Associations between sugar-sweetened beverages before and during pregnancy and offspring overweight/obesity in Japanese women: the TMM BirThree Cohort Study. Public Health Nutrition. 2023; 26 (6): 1222-1229. doi:10.1017/S1368980023000307 |
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| 32. |
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Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Infertility Treatment and Hypertension in Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Reproductive Medicine. 2023; 4 (2): 89-99. doi:10.3390/reprodmed4020010 |
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| 33. |
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Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal social isolation in the perinatal period and early childhood development: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Social Psychiatry and Psychiatric Epidemiology. 2023; 58 (11): 1593-1601. doi:10.1007/s00127-023-02498-w |
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| 34. |
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Ohseto Hisashi, Ishikuro Mami, Obara Taku, et al. Dietary calcium intake was related to the onset of pre‐eclampsia: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2023; 25 (1): 61-70. doi:10.1111/jch.14606 |
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| 35. |
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Kobayashi Tomoko, Kobayashi Mika, Minegishi Naoko, et al. Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2023; 259 (2): 2022.J103. doi:10.1620/tjem.2022.J103 |
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| 36. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Social isolation and postnatal bonding disorder in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2022; 25 (6): 1079-1086. doi:10.1007/s00737-022-01266-0 |
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| 37. |
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Kawaguchi Chikana, Murakami Keiko, Ishikuro Mami, et al. Cumulative exposure to maternal psychological distress in the prenatal and postnatal periods and atopic dermatitis in children: findings from the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2022; 22 (1): 242. doi:10.1186/s12884-022-04556-8 |
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| 38. |
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Takahashi Ippei, Murakami Keiko, Kobayashi Mika, et al. Association of maternal psychological distress and the use of childcare facilities with children's behavioral problems: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Psychiatry. 2022; 22 (1): 693. doi:10.1186/s12888-022-04330-2 |
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| 39. |
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Noda Aoi, Ishikuro Mami, Obara Taku, et al. Association between maternal infertility treatment and child neurodevelopment: findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study in Miyagi and Iwate Prefectures, Japan. BMJ Open. 2022; 12 (6): e060944. doi:10.1136/bmjopen-2022-060944 |
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| 40. |
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Yonezawa Yudai, Ueno Fumihiko, Obara Taku, et al. Fruit and vegetable consumption before and during pregnancy and developmental delays in offspring aged 2 years in Japan. British Journal of Nutrition. 2022; 127 (8): 1250-1258. doi:10.1017/S0007114521002154 |
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| 41. |
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Yonezawa Yudai, Obara Taku, Yamashita Takahiro, et al. Grain consumption before and during pregnancy and birth weight in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Nutrition. 2022; 76 (2): 261-269. doi:10.1038/s41430-021-00939-w |
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| 42. |
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Ohseto Hisashi, Ishikuro Mami, Obara Taku, et al. Preeclampsia prediction model using the dipstick test for proteinuria during early gestation. Hypertension Research in Pregnancy. 2022; 10 (3): HRP2022-002. doi:10.14390/jsshp.HRP2022-002 |
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| 43. |
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Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of epidemiology. 2022; 32 (2): 69-79. doi:10.2188/jea.JE20200338 |
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| 44. |
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Yamashita Takahiro, Obara Taku, Yonezawa Yudai, et al. Dietary patterns before and during pregnancy and small for gestational age in Japan: a prospective birth cohort study. Nutrition Journal. 2022; 21 (1): 57. doi:10.1186/s12937-022-00808-7 |
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| 45. |
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Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 2022; 21 (1): 71. doi:10.1186/s12937-022-00822-9 |
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| 46. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal personality and postpartum mental disorders in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Scientific Reports. 2022; 12 (1): 6400. doi:10.1038/s41598-022-09944-w |
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| 47. |
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Iwama Noriyuki, Obara Taku, Ishikuro Mami, et al. Risk scores for predicting small for gestational age infants in Japan: The TMM birthree cohort study. Scientific Reports. 2022; 12 (1): 8921. doi:10.1038/s41598-022-12892-0 |
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| 48. |
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Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Social isolation and insomnia among pregnant women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Sleep Health. 2022; 8 (6): 714-720. doi:10.1016/j.sleh.2022.08.007 |
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| 49. |
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Kikuchi Daisuke, Obara Taku, Usuzaki Takuma, et al. Evaluating folic acid supplementation among Japanese pregnant women with dietary intake of folic acid lower than 480 µg per day: results from TMM BirThree Cohort Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2022; 35 (5): 964-969. doi:10.1080/14767058.2020.1739020 |
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| 50. |
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Ishikuro Mami, Noda Aoii, Murakami Keiko, et al. Families’ Health after the Great East Japan Earthquake: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2022; 256 (2): 93-101. doi:10.1620/tjem.256.93 |
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| 51. |
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Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Maternal personality and alcohol use during pregnancy in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Addictive Behaviors. 2021; 122 : 107020. doi:10.1016/j.addbeh.2021.107020 |
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| 52. |
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Yamashita Takahiro, Murakami Keiko, Obara Taku, et al. Living environments long-term after the Great East Japan Earthquake and nutritional intake among recent mothers. Asia Pacific journal of clinical nutrition. 2021; 30 (4): 651-661. doi:10.6133/apjcn.202112_30(4).0012 |
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| 53. |
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Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of education and work status with alcohol use and cessation among pregnant women in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Public Health. 2021; 21 (1): 1400. doi:10.1186/s12889-021-11461-w |
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| 54. |
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Ogishima Soichi, Nagaie Satoshi, Mizuno Satoshi, et al. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Human Genome Variation. 2021; 8 (1): 44. doi:10.1038/s41439-021-00175-5 |
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| 55. |
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Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Social Predictors of Continued and Indoor Smoking Among Partners of Non-smoking Pregnant Women: The TMM BirThree Cohort Study. Journal of Epidemiology. 2021; 31 (12): JE20200313. doi:10.2188/jea.JE20200313 |
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| 56. |
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Ishikuro Mami, Murakami Keiko, Yokozeki Fumiya, et al. Hypertension in pregnancy as a possible factor for child autistic behavior at two years old. Pregnancy Hypertension. 2021; 25 (8): 88-90. doi:10.1016/j.preghy.2021.05.020 |
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| 57. |
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Usuzaki Takuma, Ishikuro Mami, Murakami Keiko, et al. How can we evaluate whether an association is truly inter-generational?. Journal of Hypertension. 2020; 38 (9): 1866-1868. doi:10.1097/HJH.0000000000002507 |
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| 58. |
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Yonezawa Yudai, Obara Taku, Yamashita Takahiro, et al. Fruit and vegetable consumption before and during pregnancy and birth weight of new-borns in Japan: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 2020; 19 (1): 80. doi:10.1186/s12937-020-00595-z |
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| 59. |
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Usuzaki Takuma, Ishikuro Mami, Metoki Hirohito, et al. Comparison among research, home, and office blood pressure measurements for pregnant women: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2020; 22 (11): 2004-2013. doi:10.1111/jch.14050 |
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| 60. |
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Narita Akira, Nagai Masato, Mizuno Satoshi, et al. Clustering by phenotype and genome-wide association study in autism. Translational Psychiatry. 2020; 10 (1): 290. doi:10.1038/s41398-020-00951-x |
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