Tohoku University Tohoku Medical Megabank Organization (Eiichi N. Kodama)
2024.02.22

1.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2024; : 64535. doi:10.5551/jat.64535  
2.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center. Hypertension Research. 2023; : . doi:10.1038/s41440-023-01484-8  
3.   Hatanaka Rieko, Nakaya Naoki, Kogure Mana, et al. The risk of withdrawal from hypertension treatment in coastal areas after the Great East Japan Earthquake: the TMM CommCohort Study. Hypertension Research. 2023; 46 (12): 2718-2728. doi:10.1038/s41440-023-01454-0  
4.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. Association of Central Blood Pressure and Carotid Intima Media Thickness with New-Onset Hypertension in People with High Normal Blood Pressure. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64151. doi:10.5551/jat.64151  
5.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (3): 63523. doi:10.5551/jat.63523  
6.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (10): 64039. doi:10.5551/jat.64039  
7.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64425. doi:10.5551/jat.64425  
8.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. The Association of Lung Function and Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (8): 63826. doi:10.5551/jat.63826  
9.   Iwasaki Yudai, Takei Yusuke, Yamada Mitsuhiro, et al. Circulating Extracellular Vesicle Levels in Patients with Coronavirus Disease 2019 Coagulopathy: A Prospective Cohort Study. Journal of Clinical Medicine. 2023; 12 (10): 3460. doi:10.3390/jcm12103460  
10.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Combined Fat Mass and Fat-free Mass Indices and Lung Function Among Japanese Population: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2023; : JE20220355. doi:10.2188/jea.JE20220355  
11.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Hypertension. 2023; 41 (3): 443-452. doi:10.1097/HJH.0000000000003356  
12.   Ide Satoshi, Ishikane Masahiro, Aoyagi Kensuke, et al. Investigation of oral macrolide prescriptions in Japan using a retrospective claims database, 2013–2018. PLOS ONE. 2023; 18 (6): e0287297. doi:10.1371/journal.pone.0287297  
13.   Itoh Naoya, Kawabata Takanori, Akazawa Nana, et al. Reduction strategies for inpatient oral third-generation cephalosporins at a cancer center: An interrupted time-series analysis. PLOS ONE. 2023; 18 (2): e0281518. doi:10.1371/journal.pone.0281518  
14.   Suzuki Tetsuya, Morioka Shinichiro, Yamamoto Kei, et al. Nasopharyngeal SARS-CoV-2 may not be dispersed by a high-flow nasal cannula. Scientific Reports. 2023; 13 (1): 2669. doi:10.1038/s41598-023-29740-4  
15.   Kobayashi Tomoko, Kobayashi Mika, Minegishi Naoko, et al. Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2023; 259 (2): 2022.J103. doi:10.1620/tjem.2022.J103  
16.   Sasano Mina, Hayashi Hironori, Kawaji Kumi, et al. Establishing an accurate and sensitive in vitro drug screening system for human adenovirus infection with human corneal cells. Virology. 2023; 581 : 34-38. doi:10.1016/j.virol.2023.02.005  
17.   Makino Yuko, Oe Chihiro, Iwama Kazuya, et al. Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors. Communications Biology. 2022; 5 (1): 619. doi:10.1038/s42003-022-03555-x  
18.   Nomoto Hidetoshi, Asai Yusuke, Hayakawa Kayoko, et al. Impact of the COVID-19 pandemic on racial and ethnic minorities in Japan. Epidemiology and Infection. 2022; 150 : e202. doi:10.1017/S0950268822001674  
19.   Morioka Shinichiro, Tan Ban Hock, Kikuchi Hiroe, et al. Factors Associated With Prolonged Psychological Distress Among Nurses and Physicians Engaged in COVID-19 Patient Care in Singapore and Japan. Frontiers in Psychiatry. 2022; 13 : . doi:10.3389/fpsyt.2022.781796  
20.   Takahata Hanako, Onishi Kazunari, Nomoto Hidetoshi, et al. Surveillance and risk assessment of health screening for vaccine-preventable diseases among international students in Japan: A cross-sectional study in 2020. Human Vaccines & Immunotherapeutics. 2022; 18 (6): . doi:10.1080/21645515.2022.2136914  
21.   Yajima Takehiro, Takahashi Hiroshi, Kimura Nozomu, et al. Comparison of sputum specimens and nasopharyngeal swab specimens for diagnosis of acute human metapneumovirus-related lower respiratory tract infections in adults. Journal of Clinical Virology. 2022; 154 : 105238. doi:10.1016/j.jcv.2022.105238  
22.   Takase Masato, Nakamura Tomohiro, Hirata Takumi, et al. Association between fat mass index, fat‐free mass index and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community‐based Cohort Study. Journal of Diabetes Investigation. 2022; 13 (5): 858-867. doi:10.1111/jdi.13729  
23.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of epidemiology. 2022; 32 (2): 69-79. doi:10.2188/jea.JE20200338  
24.   Oshima Kengo, Nakajima Chie, Hirata Kazushige, et al. Disseminated tuberculosis with paradoxical reactions caused by a Mycobacterium tuberculosis strain belonging to the Indo-Oceanic lineage: An imported case in Japan. Journal of Infection and Chemotherapy. 2022; 28 (7): 965-970. doi:10.1016/j.jiac.2022.02.008  
25.   Itoh Naoya, Akazawa Nana, Ishikane Masahiro, et al. Lessons learned from an outbreak of COVID-19 in the head and neck surgery ward of a Japanese cancer center during the sixth wave by Omicron. Journal of Infection and Chemotherapy. 2022; 28 (12): 1610-1615. doi:10.1016/j.jiac.2022.08.010  
26.   Ohata Yoshitsugu, Tomonaga Mitsunori, Watanabe Yasuo, et al. Antiviral Activity and Resistance Profile of the Novel HIV-1 Non-Catalytic Site Integrase Inhibitor JTP-0157602. Journal of Virology. 2022; 96 (6): . doi:10.1128/jvi.01843-21  
27.   Fuse Nobuo, Sakurai Miyuki, Motoike Ikuko N., et al. Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan. Ophthalmology Science. 2022; 2 (1): 100113. doi:10.1016/j.xops.2022.100113  
28.   Iwamoto Noriko, Morisaki Naho, Uda Kazuhiro, et al. Change in use of pediatric oral antibiotics in Japan, pre‐ and post‐implementation of an antimicrobial resistance action plan. Pediatrics International. 2022; 64 (1): . doi:10.1111/ped.15197  
29.   Itoh Naoya, Akazawa Nana, Kanawaku Eri, et al. Effects of infectious disease consultation and antimicrobial stewardship program at a Japanese cancer center: An interrupted time-series analysis. PLOS ONE. 2022; 17 (1): e0263095. doi:10.1371/journal.pone.0263095  
30.   Sano Hirohito, Murakami Koji, Yokoyama Hisayuki, et al. COVID-19 in a Hairy Cell Leukemia Patient: A Rare Case Report. The Tohoku Journal of Experimental Medicine. 2022; 258 (1): 2022.J058. doi:10.1620/tjem.2022.J058  
31.   Takase Masato, Nakamura Tomohiro, Tsuchiya Naho, et al. Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study. Clinical and Experimental Hypertension. 2021; 43 (7): 610-621. doi:10.1080/10641963.2021.1925681  
32.   Yamada Mitsuhiro, Motoike Ikuko N., Kojima Kaname, et al. Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator. Communications Biology. 2021; 4 (1): 1288. doi:10.1038/s42003-021-02813-8  
33.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study profile of the tohoku medical megabank community-based cohort study. Journal of Epidemiology. 2021; 31 (1): 65-76. doi:10.2188/jea.JE20190271  
34.   Hattori Shin-ichiro, Higashi-Kuwata Nobuyo, Hayashi Hironori, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature Communications. 2021; 12 (1): 668. doi:10.1038/s41467-021-20900-6  
35.   Oe Chihiro, Hayashi Hironori, Hirata Kazushige, et al. Pyrimidine Analogues as a New Class of Gram-Positive Antibiotics, Mainly Targeting Thymineless-Death Related Proteins. ACS Infectious Diseases. 2020; 6 (6): 1490-1500. doi:10.1021/acsinfecdis.9b00305  
36.   Saito Sho, Hayakawa Kayoko, Tsuzuki Shinya, et al. A Matched Case-Case-Control Study of the Impact of Clinical Outcomes and Risk Factors of Patients with IMP-Type Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae in Japan. Antimicrobial Agents and Chemotherapy. 2020; 65 (3): 251-257. doi:10.1128/AAC.01483-20  
37.   Nakagawara Kohsuke, Hayashi Hironori, Kawaji Kumi, et al. Application of human lymphoid cells for the evaluation of antivirals against human adenovirus type 19: Zalcitabine has superior activity compared to cidofovir. Antiviral Chemistry and Chemotherapy. 2020; 28 : 204020662092131. doi:10.1177/2040206620921319  
38.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169  
39.   Tsukada Kento, Shinki Shono, Kaneko Akiho, et al. Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones. Nature Communications. 2020; 11 (1): 1830. doi:10.1038/s41467-020-15664-4  
40.   Oikawa Yoshitsugu, Izumi Rumiko, Koide Masashi, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLOS ONE. 2020; 15 (12): e0231064. doi:10.1371/journal.pone.0231064  
41.   Tsuboi Akito, Matsui Hiroyuki, Shiraishi Naru, et al. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 251 (2): 97-115. doi:10.1620/tjem.251.97  
42.   Siarot Lowela, Chutiwitoonchai Nopporn, Sato Hirotaka, et al. Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening. Biochemical and Biophysical Research Communications. 2018; 503 (4): 2970-2976. doi:10.1016/j.bbrc.2018.08.079  
43.   Kikuchi Haruhisa, Kawai Kosuke, Nakashiro Yota, et al. Construction of a Meroterpenoid‐Like Compounds Library Based on Diversity‐Enhanced Extracts. Chemistry – A European Journal. 2018; 25 (4): chem.201805417. doi:10.1002/chem.201805417  
44.   Watanabe Masahiro, Hashimoto Koichi, Abe Yusaku, et al. A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo. PLOS ONE. 2016; 11 (9): e0162823. doi:10.1371/journal.pone.0162823  
45.   Salie Zhe Li, Kirby Karen A., Michailidis Eleftherios, et al. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA). Proceedings of the National Academy of Sciences. 2016; 113 (33): 9274-9279. doi:10.1073/pnas.1605223113  
46.   Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, et al. Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method. Antiviral Chemistry and Chemotherapy. 2015; 24 (2): 77-82. doi:10.1177/2040206615614164  
47.   Asai Teigo, Tsukada Kento, Ise Satomi, et al. Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides. Nature Chemistry. 2015; 7 (9): 737-743. doi:10.1038/nchem.2308  
48.   Hachiya Atsuko, Reeve Aaron B, Marchand Bruno, et al. Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs. Antimicrobial Agents and Chemotherapy. 2013; 57 (9): 4554-4558. doi:10.1128/AAC.00283-13  
49.   Shimane Kazuki, Kawaji Kumi, Miyamoto Fusako, et al. HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains. Antimicrobial Agents and Chemotherapy. 2013; 57 (8): 4035-4038. doi:10.1128/AAC.00237-13  
50.   Maeda Kenji, Desai Darshan V, Aoki Manabu, et al. Delayed emergence of HIV-1 variants resistant to 4’-ethynyl-2-fluoro-2’-deoxyadenosine: comparative sequential passage study with lamivudine, tenofovir, emtricitabine and BMS-986001. Antiviral Therapy. 2013; 19 (2): 179-189. doi:10.3851/IMP2697