Tohoku University Tohoku Medical Megabank Organization (Eiichi N. Kodama)

1.   Makino Yuko, Oe Chihiro, Iwama Kazuya, et al. Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors. Communications Biology. 2022; 5 (1): 619. doi:10.1038/s42003-022-03555-x  
2.   Morioka Shinichiro, Tan Ban Hock, Kikuchi Hiroe, et al. Factors Associated With Prolonged Psychological Distress Among Nurses and Physicians Engaged in COVID-19 Patient Care in Singapore and Japan. Frontiers in Psychiatry. 2022; 13 : . doi:10.3389/fpsyt.2022.781796  
3.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2022; : 63523. doi:10.5551/jat.63523  
4.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. The Association of Lung Function and Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2022; : 63826. doi:10.5551/jat.63826  
5.   Yajima Takehiro, Takahashi Hiroshi, Kimura Nozomu, et al. Comparison of sputum specimens and nasopharyngeal swab specimens for diagnosis of acute human metapneumovirus-related lower respiratory tract infections in adults. Journal of Clinical Virology. 2022; 154 : 105238. doi:10.1016/j.jcv.2022.105238  
6.   Takase Masato, Nakamura Tomohiro, Hirata Takumi, et al. Association between fat mass index, fat‐free mass index and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community‐based Cohort Study. Journal of Diabetes Investigation. 2022; 13 (5): 858-867. doi:10.1111/jdi.13729  
7.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of epidemiology. 2022; 32 (2): 69-79. doi:10.2188/jea.JE20200338  
8.   Oshima Kengo, Nakajima Chie, Hirata Kazushige, et al. Disseminated tuberculosis with paradoxical reactions caused by a Mycobacterium tuberculosis strain belonging to the Indo-Oceanic lineage: An imported case in Japan. Journal of Infection and Chemotherapy. 2022; 28 (7): 965-970. doi:10.1016/j.jiac.2022.02.008  
9.   Itoh Naoya, Akazawa Nana, Ishikane Masahiro, et al. Lessons learned from an outbreak of COVID-19 in the head and neck surgery ward of a Japanese cancer center during the sixth wave by Omicron. Journal of Infection and Chemotherapy. 2022; 28 (12): 1610-1615. doi:10.1016/j.jiac.2022.08.010  
10.   Ohata Yoshitsugu, Tomonaga Mitsunori, Watanabe Yasuo, et al. Antiviral Activity and Resistance Profile of the Novel HIV-1 Non-Catalytic Site Integrase Inhibitor JTP-0157602. Journal of Virology. 2022; 96 (6): . doi:10.1128/jvi.01843-21  
11.   Fuse Nobuo, Sakurai Miyuki, Motoike Ikuko N., et al. Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan. Ophthalmology Science. 2022; 2 (1): 100113. doi:10.1016/j.xops.2022.100113  
12.   Iwamoto Noriko, Morisaki Naho, Uda Kazuhiro, et al. Change in use of pediatric oral antibiotics in Japan, pre‐ and post‐implementation of an antimicrobial resistance action plan. Pediatrics International. 2022; 64 (1): . doi:10.1111/ped.15197  
13.   Itoh Naoya, Akazawa Nana, Kanawaku Eri, et al. Effects of infectious disease consultation and antimicrobial stewardship program at a Japanese cancer center: An interrupted time-series analysis. PLOS ONE. 2022; 17 (1): e0263095. doi:10.1371/journal.pone.0263095  
14.   Sano Hirohito, Murakami Koji, Yokoyama Hisayuki, et al. COVID-19 in a Hairy Cell Leukemia Patient: A Rare Case Report. The Tohoku Journal of Experimental Medicine. 2022; 258 (1): 2022.J058. doi:10.1620/tjem.2022.J058  
15.   Yamada Mitsuhiro, Motoike Ikuko N., Kojima Kaname, et al. Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator. Communications Biology. 2021; 4 (1): 1288. doi:10.1038/s42003-021-02813-8  
16.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study profile of the tohoku medical megabank community-based cohort study. Journal of Epidemiology. 2021; 31 (1): 65-76. doi:10.2188/jea.JE20190271  
17.   Hattori Shin-ichiro, Higashi-Kuwata Nobuyo, Hayashi Hironori, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature Communications. 2021; 12 (1): 668. doi:10.1038/s41467-021-20900-6  
18.   Oe Chihiro, Hayashi Hironori, Hirata Kazushige, et al. Pyrimidine Analogues as a New Class of Gram-Positive Antibiotics, Mainly Targeting Thymineless-Death Related Proteins. ACS Infectious Diseases. 2020; 6 (6): 1490-1500. doi:10.1021/acsinfecdis.9b00305  
19.   Saito Sho, Hayakawa Kayoko, Tsuzuki Shinya, et al. A Matched Case-Case-Control Study of the Impact of Clinical Outcomes and Risk Factors of Patients with IMP-Type Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae in Japan. Antimicrobial Agents and Chemotherapy. 2020; 65 (3): 251-257. doi:10.1128/AAC.01483-20  
20.   Nakagawara Kohsuke, Hayashi Hironori, Kawaji Kumi, et al. Application of human lymphoid cells for the evaluation of antivirals against human adenovirus type 19: Zalcitabine has superior activity compared to cidofovir. Antiviral Chemistry and Chemotherapy. 2020; 28 : 204020662092131. doi:10.1177/2040206620921319  
21.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169  
22.   Tsukada Kento, Shinki Shono, Kaneko Akiho, et al. Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones. Nature Communications. 2020; 11 (1): 1830. doi:10.1038/s41467-020-15664-4  
23.   Oikawa Yoshitsugu, Izumi Rumiko, Koide Masashi, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLOS ONE. 2020; 15 (12): e0231064. doi:10.1371/journal.pone.0231064  
24.   Tsuboi Akito, Matsui Hiroyuki, Shiraishi Naru, et al. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 251 (2): 97-115. doi:10.1620/tjem.251.97  
25.   Siarot Lowela, Chutiwitoonchai Nopporn, Sato Hirotaka, et al. Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening. Biochemical and Biophysical Research Communications. 2018; 503 (4): 2970-2976. doi:10.1016/j.bbrc.2018.08.079  
26.   Kikuchi Haruhisa, Kawai Kosuke, Nakashiro Yota, et al. Construction of a Meroterpenoid‐Like Compounds Library Based on Diversity‐Enhanced Extracts. Chemistry – A European Journal. 2018; 25 (4): chem.201805417. doi:10.1002/chem.201805417  
27.   Watanabe Masahiro, Hashimoto Koichi, Abe Yusaku, et al. A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo. PLOS ONE. 2016; 11 (9): e0162823. doi:10.1371/journal.pone.0162823  
28.   Salie Zhe Li, Kirby Karen A., Michailidis Eleftherios, et al. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA). Proceedings of the National Academy of Sciences. 2016; 113 (33): 9274-9279. doi:10.1073/pnas.1605223113  
29.   Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, et al. Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method. Antiviral Chemistry and Chemotherapy. 2015; 24 (2): 77-82. doi:10.1177/2040206615614164  
30.   Asai Teigo, Tsukada Kento, Ise Satomi, et al. Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides. Nature Chemistry. 2015; 7 (9): 737-743. doi:10.1038/nchem.2308  
31.   Hachiya Atsuko, Reeve Aaron B, Marchand Bruno, et al. Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs. Antimicrobial Agents and Chemotherapy. 2013; 57 (9): 4554-4558. doi:10.1128/AAC.00283-13  
32.   Shimane Kazuki, Kawaji Kumi, Miyamoto Fusako, et al. HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains. Antimicrobial Agents and Chemotherapy. 2013; 57 (8): 4035-4038. doi:10.1128/AAC.00237-13  
33.   Maeda Kenji, Desai Darshan V, Aoki Manabu, et al. Delayed emergence of HIV-1 variants resistant to 4’-ethynyl-2-fluoro-2’-deoxyadenosine: comparative sequential passage study with lamivudine, tenofovir, emtricitabine and BMS-986001. Antiviral Therapy. 2013; 19 (2): 179-189. doi:10.3851/IMP2697