Tohoku University Tohoku Medical Megabank Organization (Akira Uruno)
2020.11.20

1.   Suzuki Takafumi, Uruno Akira, Yumoto Akane, et al. Nrf2 contributes to the weight gain of mice during space travel. Communications Biology. 2020; 3 (1): 496. doi:10.1038/s42003-020-01227-2  
2.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2  
3.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0  
4.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200338  
5.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20190271  
6.   Uruno Akira, Matsumaru Daisuke, Ryoke Rie, et al. Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice. Molecular and Cellular Biology. 2020; 40 (6): . doi:10.1128/MCB.00467-19  
7.   Rashad Sherif, Saigusa Daisuke, Yamazaki Takahiro, et al. Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach. Scientific Reports. 2020; 10 (1): 6507. doi:10.1038/s41598-020-63483-w  
8.   Saigusa Daisuke, Saito Ritsumi, Kawamoto Komei, et al. Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Analytical Chemistry. 2019; 91 (14): 8979-8986. doi:10.1021/acs.analchem.9b01159  
9.   Keleku-Lukwete Nadine, Suzuki Mikiko, Panda Harit, et al. Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice. Blood Advances. 2019; 3 (8): 1285-1297. doi:10.1182/bloodadvances.2018017574  
10.   Kurosawa Ryo, Satoh Kimio, Kikuchi Nobuhiro, et al. Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension. Circulation Research. 2019; 125 (3): 309-327. doi:10.1161/CIRCRESAHA.119.315229  
11.   Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7  
12.   Uranbileg Baasanjav, Ito Nobuko, Kurano Makoto, et al. Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. Scientific Reports. 2019; 9 (1): 16578. doi:10.1038/s41598-019-52999-5  
13.   Rashad Sherif, Niizuma Kuniyasu, Saigusa Daisuke, et al. Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia. Neuroscience. 2018; 384 : 188-202. doi:10.1016/j.neuroscience.2018.05.015  
14.   Sato Kota, Saigusa Daisuke, Saito Ritsumi, et al. Metabolomic changes in the mouse retina after optic nerve injury. Scientific Reports. 2018; 8 (1): 11930. doi:10.1038/s41598-018-30464-z  
15.   Yagishita Yoko, Uruno Akira, Fukutomi Toshiaki, et al. Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress. Cell Reports. 2017; 18 (8): 2030-2044. doi:10.1016/j.celrep.2017.01.064  
16.   Yagishita Yoko, Fukutomi Toshiaki, Sugawara Akira, et al. Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice. Diabetes. 2014; 63 (2): 605-618. doi:10.2337/db13-0909