Tohoku University Tohoku Medical Megabank Organization (2023)
2025.05.01

1.   Ebata Akiko, Suzuki Takashi, Shoji-Harada Narumi, et al. Immunolocalization of Cytoplasmic ER in ER-negative Breast Carcinoma as a Potent Favorable Prognostic Predictor. ACTA HISTOCHEMICA ET CYTOCHEMICA. 2023; 56 (4): 23-00016. doi:10.1267/ahc.23-00016  
2.   Osada Yoshinari, Kanamori Masayuki, Osawa Shin-Ichiro, et al. Visualization of the lenticulostriate arteries, long insular arteries, and long medullary arteries on intra-arterial computed tomography angiography with ultrahigh resolution in patients with glioma. Acta Neurochirurgica. 2023; 165 (12): 4213-4219. doi:10.1007/s00701-023-05794-1  
3.   Kobayashi Masayuki, Ishikuro Mami, Obara Taku, Kuriyama Shinichi. Weight‐for‐age z ‐scores of Japanese children using the World Health Organization Child Growth Standards. Acta Paediatrica. 2023; 112 (4): 776-778. doi:10.1111/apa.16662  
4.   Gearry Richard, Fukudo Shin, Barbara Giovanni, et al. Consumption of 2 Green Kiwifruits Daily Improves Constipation and Abdominal Comfort—Results of an International Multicenter Randomized Controlled Trial. American Journal of Gastroenterology. 2023; 118 (6): 1058-1068. doi:10.14309/ajg.0000000000002124  
5.   Nakayama Shingo, Satoh Michihiro, Metoki Hirohito, et al. Association Between Ambulatory Blood Pressure and Risk of Home Hypertension in a Normotensive Population: The Ohasama Study. American Journal of Hypertension. 2023; 36 (3): 151-158. doi:10.1093/ajh/hpac121  
6.   Hanyuda Akiko, Goto Atsushi, Nakatochi Masahiro, et al. Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population. American Journal of Ophthalmology. 2023; 245 : 193-201. doi:10.1016/j.ajo.2022.09.004  
7.   Someko Hidehiro, Kataoka Yuki, Obara Taku. Drug fever: a narrative review. Annals of Clinical Epidemiology. 2023; 5 (4): 23013. doi:10.37737/ace.23013  
8.   Machida Toshiya, Obara Taku, Ishikuro Mami, et al. Liver steatosis and fibrosis markers’ association with cardiovascular and renal damage in Japanese adults: the TMM BirThree cohort study. Annals of Hepatology. 2023; 28 (1): 100761. doi:10.1016/j.aohep.2022.100761  
9.   Uruno Akira, Yamamoto Masayuki. The KEAP1-NRF2 System and Neurodegenerative Diseases. Antioxidants & Redox Signaling. 2023; 38 (13-15): 974-988. doi:10.1089/ars.2023.0234  
10.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Effect of social participation on the association between frailty and disability. Archives of Gerontology and Geriatrics. 2023; 110 : 104989. doi:10.1016/j.archger.2023.104989  
11.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal postnatal bonding disorder and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2023; 26 (2): 219-226. doi:10.1007/s00737-023-01298-0  
12.   Kumondai Masaki, Maekawa Masamitsu, Hishinuma Eiji, et al. Development of a Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analytical Method for Urinary Endogenous Substrates and Metabolites for Predicting Cytochrome P450 3A4 Activity. Biological and Pharmaceutical Bulletin. 2023; 46 (3): b22-00840. doi:10.1248/bpb.b22-00840  
13.   Hasegawa Ryoko, Saito-Nakaya Kumi, Gu Li, et al. Maternal separation and TNBS-induced gut inflammation synergistically alter the sexually differentiated stress response in rats. BioPsychoSocial Medicine. 2023; 17 (1): 7. doi:10.1186/s13030-022-00258-x  
14.   Ishikawa Tomofumi, Kawame Hiroshi, Mano Nariyasu, Obara Taku. Real‐world prevalence, time of diagnosis, and co‐occurrence patterns of birth defects in live‐born infants, 2014–2020: A health administrative database study in Japan. Birth Defects Research. 2023; 115 (18): 1723-1736. doi:10.1002/bdr2.2247  
15.   Nakai Taku, Iwamura Yuma, Kato Koichiro, et al. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice. Blood Advances. 2023; 7 (15): 3793-3805. doi:10.1182/bloodadvances.2023009798  
16.   Katayama Osamu, Lee Sangyoon, Bae Seongryu, et al. Differential effects of lifestyle activities on disability incidence based on neighborhood amenities. BMC Geriatrics. 2023; 23 (1): 483. doi:10.1186/s12877-023-04170-z  
17.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and infant birth weight: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Pregnancy and Childbirth. 2023; 23 (1): 268. doi:10.1186/s12884-023-05603-8  
18.   Maeda Yuto, Doi Satomi, Isumi Aya, et al. Association between poor parent-daughter relationships and the risk of hyperglycemia in pregnancy: a hospital-based prospective cohort study in Japan. BMC Pregnancy and Childbirth. 2023; 23 (1): 227. doi:10.1186/s12884-023-05535-3  
19.   Mizuno Satoshi, Nagaie Satoshi, Tamiya Gen, et al. Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy and Childbirth. 2023; 23 (1): 628. doi:10.1186/s12884-023-05919-5  
20.   Chiba Ippei, Takahashi Masayoshi, Lee Sangyoon, et al. Association between COVID-19 emergency declarations and physical activity among community-dwelling older adults enrolled in a physical activity measurement program: Evidence from a retrospective observational study using the regression discontinuity desig. BMC Public Health. 2023; 23 (1): 998. doi:10.1186/s12889-023-15932-0  
21.   Murakami Keiko, Aida Jun, Kuriyama Shinichi, Hashimoto Hideki. Associations of health literacy with dental care use and oral health status in Japan. BMC Public Health. 2023; 23 (1): 1074. doi:10.1186/s12889-023-15866-7  
22.   Matsuda Ayako, Asayama Kei, Obara Taku, et al. Behavioral changes of preventive activities of influenza among children in satellite cities of a metropolitan area of Tokyo, Japan, by the COVID-19 pandemic. BMC Public Health. 2023; 23 (1): 727. doi:10.1186/s12889-023-15606-x  
23.   Ishikawa Hirono, Ogawa Runa, Otsuki Aki, et al. Effect modification by geographic area on the association between health literacy and self-rated health: a nationwide cross-sectional study in Japan. BMC Public Health. 2023; 23 (1): 952. doi:10.1186/s12889-023-15897-0  
24.   Ohneda Kinuko, Hamanaka Yohei, Kawame Hiroshi, et al. Returning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants. Breast Cancer. 2023; 30 (1): 110-120. doi:10.1007/s12282-022-01404-7  
25.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling. Cancer & Metabolism. 2023; 11 (1): 16. doi:10.1186/s40170-023-00317-z  
26.   Tsuchiya Masami, Obara Taku, Kikuchi Masafumi, Mano Nariyasu. The prevalence of end-of-life chemotherapy and targeted therapy in Japan, assessed using a health claims database. Cancer Chemotherapy and Pharmacology. 2023; 91 (6): 501-506. doi:10.1007/s00280-023-04535-6  
27.   Yoshihara Kosuke, Baba Tsukasa, Tokunaga Hideki, et al. Homologous recombination inquiry through ovarian malignancy investigations: JGOG3025 Study. Cancer Science. 2023; 114 (6): 2515-2523. doi:10.1111/cas.15747  
28.   Shimizu Takanori, Iwama Noriyuki, Tokunaga Hideki, et al. Precautions during Direct Oral Anticoagulant Introduction in Gynecologic Malignancies: A Single-Center Retrospective Cohort Study. Cancers. 2023; 15 (4): 1132. doi:10.3390/cancers15041132  
29.   Hirose Wataru, Horiuchi Makoto, Li Donghan, et al. Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium. Cellular and Molecular Gastroenterology and Hepatology. 2023; 15 (1): 153-178. doi:10.1016/j.jcmgh.2022.09.004  
30.   Shinoda Genki, Nagaoka Yudai, Ueno Fumihiko, et al. Association between being Overweight in Young Childhood and during School Age and Puberty. Children. 2023; 10 (5): 909. doi:10.3390/children10050909  
31.   Shimizu Ritsuko, Hirano Ikuo, Hasegawa Atsushi, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Communications Biology. 2023; 6 (1): 875. doi:10.1038/s42003-023-05251-w  
32.   Orui Masatsugu, Saeki Suzuka, Kozakai Yuki, et al. The Impact of the COVID-19 Pandemic on Suicide Rate Trends in the Tsunami-Disaster-Affected Area Following the Great East Japan Earthquake. Crisis. 2023; 44 (2): 93-99. doi:10.1027/0227-5910/a000832  
33.   Oikawa Daiki, Fukui Kohei, Aoki Yuichi, et al. Enterocloster alcoholdehydrogenati sp. nov., a Novel Bacterial Species Isolated from the Feces of a Patient with Alcoholism. Current Microbiology. 2023; 80 (5): 187. doi:10.1007/s00284-023-03285-1  
34.   Hashimoto Chiaki, Shigeta Shogo, Shimada Muneaki, et al. Diagnostic Performance of Preoperative Imaging in Endometrial Cancer. Current Oncology. 2023; 30 (9): 8233-8244. doi:10.3390/curroncol30090597  
35.   Tatara Yota, Yamazaki Hiromi, Katsuoka Fumiki, et al. Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment. Current Research in Translational Medicine. 2023; 71 (1): 103367. doi:10.1016/j.retram.2022.103367  
36.   Yu Zhiqian, Sakai Mai, Fukushima Hotaka, et al. Microarray dataset of gene transcription in mouse microglia and peripheral monocytes in contextual fear conditioning. Data in Brief. 2023; 46 : 108862. doi:10.1016/j.dib.2022.108862  
37.   Takahashi So, Hatta Waku, Watanabe Kenta, et al. Prognostic Benefit of Additional Treatment After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma. Digestive Diseases and Sciences. 2023; 68 (5): 2050-2060. doi:10.1007/s10620-022-07746-8  
38.   Ogata Yohei, Hatta Waku, Koike Tomoyuki, et al. Blue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high‐risk patients: Multicenter randomized trial. Digestive Endoscopy. 2023; 35 (7): 835-844. doi:10.1111/den.14538  
39.   Ueno Fumihiko, Murakami Keiko, Nagai Masato, et al. Difficulties in Accessing Medication Records at the Time of a Large-Scale Disaster. Disaster Medicine and Public Health Preparedness. 2023; 17 : e370. doi:10.1017/dmp.2022.301  
40.   Hishinuma Eiji, Narita Yoko, Rico Evelyn Marie Gutiérrez, et al. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity. Drug Metabolism and Disposition. 2023; 51 (2): 165-173. doi:10.1124/dmd.122.001045  
41.   Sato Yu, Hishinuma Eiji, Yamazaki Shuki, et al. Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω -Hydroxylation. Drug Metabolism and Disposition. 2023; 51 (12): 1561-1568. doi:10.1124/dmd.123.001389  
42.   Makiguchi Miaki, Shimizu Makiko, Yokota Yuka, et al. Variants of Flavin-Containing Monooxygenase 3 Found in Subjects in an Updated Database of Genome Resources. Drug Metabolism and Disposition. 2023; 51 (7): 884-891. doi:10.1124/dmd.123.001310  
43.   Tsukagoshi Eri, Nakamura Ryosuke, Tanaka Yoichi, et al. Validation of a genotyping technique for a surrogate marker of HLA-B58:01 for allopurinol-induced Stevens–Johnson syndrome and toxic epidermal necrolysis in the Japanese population. Drug Metabolism and Pharmacokinetics. 2023; 49 : 100495. doi:10.1016/j.dmpk.2023.100495  
44.   Murakami Keiko, Kuriyama Shinichi, Hashimoto Hideki. Economic, cognitive, and social paths of education to health-related behaviors: evidence from a population-based study in Japan. Environmental Health and Preventive Medicine. 2023; 28 (1): 22-00178. doi:10.1265/ehpm.22-00178  
45.   Sato Shiho, Yu Zhiqian, Sakai Mai, et al. Decreased β‐hydroxybutyrate and ketogenic amino acid levels in depressed human adults. European Journal of Neuroscience. 2023; 57 (6): 1018-1032. doi:10.1111/ejn.15931  
46.   Usuzaki Takuma, Takahashi Kengo, Takagi Hidenobu, et al. Efficacy of exponentiation method with a convolutional neural network for classifying lung nodules on CT images by malignancy level. European Radiology. 2023; 33 (12): 9309-9319. doi:10.1007/s00330-023-09946-w  
47.   Inoue-Yanagimachi Maki, Himori Noriko, Uchida Keiko, et al. Changes in glial cells and neurotrophic factors due to rotenone-induced oxidative stress in Nrf2 knockout mice. Experimental Eye Research. 2023; 226 : 109314. doi:10.1016/j.exer.2022.109314  
48.   Zhang Anqi, Suzuki Takafumi, Adachi Saki, et al. Nrf2 activation improves experimental rheumatoid arthritis. Free Radical Biology and Medicine. 2023; 207 : 279-295. doi:10.1016/j.freeradbiomed.2023.07.016  
49.   Zhang Lin, Nishi Hafumi, Kinoshita Kengo. Single-cell RNA-seq public data reveal the gene regulatory network landscape of respiratory epithelial and peripheral immune cells in COVID-19 patients. Frontiers in Immunology. 2023; 14 : . doi:10.3389/fimmu.2023.1194614  
50.   Kodama Naoki, Okada Hikaru, Hachisu Masakazu, et al. A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice. Frontiers in Nutrition. 2023; 10 : 206-220. doi:10.3389/fnut.2023.1081263  
51.   Li Xue, Ono Chiaki, Warita Noriko, et al. Comprehensive evaluation of machine learning algorithms for predicting sleep–wake conditions and differentiating between the wake conditions before and after sleep during pregnancy based on heart rate variability. Frontiers in Psychiatry. 2023; 14 : . doi:10.3389/fpsyt.2023.1104222  
52.   Murakami Keiko, Kuriyama Shinichi, Hashimoto Hideki. General health literacy, COVID-19-related health literacy, and protective behaviors: evidence from a population-based study in Japan. Frontiers in Public Health. 2023; 11 : . doi:10.3389/fpubh.2023.1208815  
53.   Kobayashi Tomoko, Fujishima Fumiyoshi, Tokodai Kazuaki, et al. Detailed Courses and Pathological Findings of Colonic Perforation without Diverticula in Sisters with Musculocontractural Ehlers–Danlos Syndrome Caused by Pathogenic Variant in CHST14 (mcEDS-CHST14). Genes. 2023; 14 (5): 1079. doi:10.3390/genes14051079  
54.   Tokutomi Tomoharu, Yoshida Akiko, Fukushima Akimune, et al. Stakeholder Perception of the Implementation of Genetic Risk Testing for Twelve Multifactorial Diseases. Genes. 2023; 15 (1): 49. doi:10.3390/genes15010049  
55.   Watarai Gosuke, Suzuki Jun, Motoike Ikuko N, et al. Relationship between age‐related hearing loss and consumption of coffee and tea. Geriatrics & Gerontology International. 2023; 23 (6): 453-456. doi:10.1111/ggi.14589  
56.   Obara Taku, Ishikuro Mami, Ueno Fumihiko, et al. Antihypertensive drug use during pregnancy in Japan. Hypertension Research. 2023; 46 (2): 548-549. doi:10.1038/s41440-022-01101-0  
57.   Mikami Takahiro, Tanno Kozo, Sasaki Ryohei, et al. Association between the extent of house collapse and urine sodium-to-potassium ratio of victims affected by the 2011 Great East Japan Earthquake and Tsunami: a cross-sectional study. Hypertension Research. 2023; 46 (5): 1247-1256. doi:10.1038/s41440-023-01190-5  
58.   Satoh Michihiro. Blood pressure changes with gender-affirming hormone therapy in transgender people. Hypertension Research. 2023; 46 (3): 792-793. doi:10.1038/s41440-022-01162-1  
59.   Metoki Hirohito, Kuriyama Shinichi. Combination of genetic and environmental factors for childhood hypertension: a simple indicator of family history remains useful. Hypertension Research. 2023; 46 (4): 1061-1063. doi:10.1038/s41440-022-01165-y  
60.   Suenaga Tsukasa, Satoh Michihiro, Murakami Takahisa, et al. Cross-classification by systolic and diastolic blood pressure levels and chronic kidney disease, proteinuria, or kidney function decline. Hypertension Research. 2023; 46 (8): 1860-1869. doi:10.1038/s41440-023-01267-1  
61.   Murakami Takahisa, Satoh Michihiro, Metoki Hirohito. Long-term changes in blood pressure and their health impact. Hypertension Research. 2023; 46 (12): 2651-2653. doi:10.1038/s41440-023-01446-0  
62.   Akaishi Tetsuya, Tarasawa Kunio, Hamada Hirotaka, et al. Prenatal hypertension as the risk of eclampsia, HELLP syndrome, and critical obstetric hemorrhage. Hypertension Research. 2023; 47 (2): 455-466. doi:10.1038/s41440-023-01511-8  
63.   Tanaka Kosuke, Nishigori Hidekazu, Watanabe Zen, et al. Secondhand smoke exposure is associated with the risk of hypertensive disorders of pregnancy: the Japan Environment and Children’s Study. Hypertension Research. 2023; 46 (4): 834-844. doi:10.1038/s41440-022-01144-3  
64.   Hatanaka Rieko, Nakaya Naoki, Kogure Mana, et al. The risk of withdrawal from hypertension treatment in coastal areas after the Great East Japan Earthquake: the TMM CommCohort Study. Hypertension Research. 2023; 46 (12): 2718-2728. doi:10.1038/s41440-023-01454-0  
65.   Munakata Masanori, Hattori Tomomi, Kubota-Nakayama Fumie, et al. Home Blood Pressure-based Guidance Did Not Increase Anti-albuminuric Effects on Diagnostic Provision of Microalbuminuria in School Workers: A Miyagi Karoshi Prevention Study. Internal Medicine. 2023; 62 (8): 0107-22. doi:10.2169/internalmedicine.0107-22  
66.   Sakamoto Shusuke, Kogure Mana, Hanibuchi Tomoya, et al. Effects of greenery at different heights in neighbourhood streetscapes on leisure walking: a cross-sectional study using machine learning of streetscape images in Sendai City, Japan. International Journal of Health Geographics. 2023; 22 (1): 29. doi:10.1186/s12942-023-00351-6  
67.   Miyoshi Keitaro, Hishinuma Eiji, Matsukawa Naomi, et al. Global Proteomics for Identifying the Alteration Pathway of Niemann–Pick Disease Type C Using Hepatic Cell Models. International Journal of Molecular Sciences. 2023; 24 (21): 15642. doi:10.3390/ijms242115642  
68.   Ishikawa Tomohiko, Ogawa Takenori, Shiihara Masahiro, et al. Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials. iScience. 2023; 26 (5): 106695. doi:10.1016/j.isci.2023.106695  
69.   Takahashi Ippei, Obara Taku, Ishikuro Mami, et al. Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years. JAMA Pediatrics. 2023; 177 (10): 1039. doi:10.1001/jamapediatrics.2023.3057  
70.   Fujino Mitsunori, Morito Naoki, Hayashi Takuto, et al. Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2. JCI Insight. 2023; 8 (6): . doi:10.1172/jci.insight.163306  
71.   Moroi Rintaro, Kakuta Yoichi, Obara Taku, et al. Long‐term prognosis and clinical practice for new‐onset ulcerative colitis in the era of biologics: A Japanese retrospective study. JGH Open. 2023; 7 (10): 682-689. doi:10.1002/jgh3.12957  
72.   Taira Makiko, Mugikura Shunji, Mori Naoko, et al. Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study: Rationale, Design, and Background. JMA Journal. 2023; 6 (3): 246-264. doi:10.31662/jmaj.2022-0220  
73.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal postnatal bonding disorder and emotional/behavioral problems in preschool children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 325 : 582-587. doi:10.1016/j.jad.2023.01.044  
74.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Traumatic experiences of the Great East Japan Earthquake and postpartum depressive symptoms: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 320 : 461-467. doi:10.1016/j.jad.2022.09.139  
75.   Sato Shuichi, Imaeda Takao, Mugikura Shunji, et al. Association Between Olfactory Test Data with Multiple Levels of Odor Intensity and Suspected Cognitive Impairment: A Cross-Sectional Study. Journal of Alzheimer's Disease. 2023; 95 (4): 1469-1480. doi:10.3233/JAD-230318  
76.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. Association of Central Blood Pressure and Carotid Intima Media Thickness with New-Onset Hypertension in People with High Normal Blood Pressure. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64151. doi:10.5551/jat.64151  
77.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (3): 63523. doi:10.5551/jat.63523  
78.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (10): 64039. doi:10.5551/jat.64039  
79.   Sato Wakana, Nomura Kyoko, Satoh Michihiro, et al. Female Reproductive Events and Subclinical Atherosclerosis of the Brain and Carotid Arteriopathy: the Ohasama Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (8): 63592. doi:10.5551/jat.63592  
80.   Egawa Makiko, Kanda Eiichiro, Ohtsu Hiroshi, et al. Hypertensive Disorders of Pregnancy are Associated with Cardiovascular Disease in Middle- and Older-Aged Japanese Women. Journal of Atherosclerosis and Thrombosis. 2023; 30 (10): 63816. doi:10.5551/jat.63816  
81.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64425. doi:10.5551/jat.64425  
82.   Egawa Makiko, Kanda Eiichiro, Ohtsu Hiroshi, et al. Number of Children and Risk of Cardiovascular Disease in Japanese Women: Findings from the Tohoku Medical Megabank. Journal of Atherosclerosis and Thrombosis. 2023; 30 (2): 63527. doi:10.5551/jat.63527  
83.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. The Association of Lung Function and Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (8): 63826. doi:10.5551/jat.63826  
84.   Saito-Hakoda Akiko, Kikuchi Atsuo, Takahashi Tadahisa, et al. Familial Paget’s disease of bone with ocular manifestations and a novel TNFRSF11A duplication variant (72dup27). Journal of Bone and Mineral Metabolism. 2023; 41 (2): 193-202. doi:10.1007/s00774-022-01392-w  
85.   Shiokawa Nanako, Okazaki Tatsuma, Suzukamo Yoshimi, et al. Association between Low Forced Vital Capacity and High Pneumonia Mortality, and Impact of Muscle Power. Journal of Clinical Medicine. 2023; 12 (9): 3272. doi:10.3390/jcm12093272  
86.   Iwasaki Yudai, Takei Yusuke, Yamada Mitsuhiro, et al. Circulating Extracellular Vesicle Levels in Patients with Coronavirus Disease 2019 Coagulopathy: A Prospective Cohort Study. Journal of Clinical Medicine. 2023; 12 (10): 3460. doi:10.3390/jcm12103460  
87.   Bae Seongryu, Shimada Hiroyuki, Lee Sangyoon, et al. Subjective Cognitive Decline and Frailty Trajectories and Influencing Factors in Japanese Community-Dwelling Older Adults: A Longitudinal Study. Journal of Clinical Medicine. 2023; 12 (18): 5803. doi:10.3390/jcm12185803  
88.   Yanagisawa Yuta, Shido Kosuke, Kojima Kaname, Yamasaki Kenshi. Convolutional neural network-based skin image segmentation model to improve classification of skin diseases in conventional and non-standardized picture images. Journal of Dermatological Science. 2023; 109 (1): 30-36. doi:10.1016/j.jdermsci.2023.01.005  
89.   Tomita Hasumi, Iwama Noriyuki, Hamada Hirotaka, et al. The impact of maternal and paternal birth weights on infant birth weights: the Japan environment and children’s study. Journal of Developmental Origins of Health and Disease. 2023; 14 (6): 699-710. doi:10.1017/S2040174423000387  
90.   Orui Masatsugu. Establishment of Training System to Cope with Mental Health and Social Issues in Disaster Recovery Public Housing After the Great East Japan Earthquake. Journal of Disaster Research. 2023; 18 (5): 485-491. doi:10.20965/jdr.2023.p0485  
91.   Morisaki Naho, Obara Taku, Piedvache Aurelie, et al. Association Between Smoking and Hypertension in Pregnancy Among Japanese Women: A Meta-analysis of Birth Cohort Studies in the Japan Birth Cohort Consortium (JBiCC) and JECS. Journal of Epidemiology. 2023; 33 (10): JE20220076. doi:10.2188/jea.JE20220076  
92.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Factors Associated With Postpartum Smoking Relapse Among Women Who Quit in Early Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (1): JE20200609. doi:10.2188/jea.JE20200609  
93.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Relation of Disaster Exposure With Maternal Characteristics and Obstetric Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (3): JE20210052. doi:10.2188/jea.JE20210052  
94.   Hatta Waku, Koike Tomoyuki, Asonuma Sho, et al. Smoking history and severe atrophic gastritis assessed by pepsinogen are risk factors for the prevalence of synchronous gastric cancers in patients with gastric endoscopic submucosal dissection: a multicenter prospective cohort study. Journal of Gastroenterology. 2023; 58 (5): 433-443. doi:10.1007/s00535-023-01967-y  
95.   Sugawara Yuka, Kato Hideki, Nagasaki Masao, et al. CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome. Journal of Human Genetics. 2023; 68 (6): 427-430. doi:10.1038/s10038-023-01129-1  
96.   Hiromoto Kana, Yamada Takahiro, Tsuchiya Mio, et al. Challenges of secondary finding disclosure in genomic medicine in rare diseases: A nation-wide survey of Japanese facilities outsourcing comprehensive genetic testing. Journal of Human Genetics. 2023; 68 (1): 1-9. doi:10.1038/s10038-022-01084-3  
97.   Sugawara Yuka, Hirakawa Yosuke, Nagasu Hajime, et al. Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank. Journal of Human Genetics. 2023; 68 (2): 55-64. doi:10.1038/s10038-022-01094-1  
98.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Hypertension. 2023; 41 (3): 443-452. doi:10.1097/HJH.0000000000003356  
99.   Mitsutake Seigo, Takahashi Yoshimitsu, Otsuki Aki, et al. Chronic Diseases and Sociodemographic Characteristics Associated With Online Health Information Seeking and Using Social Networking Sites: Nationally Representative Cross-sectional Survey in Japan. Journal of Medical Internet Research. 2023; 25 : e44741. doi:10.2196/44741  
100.   Anzawa Hayato, Kinoshita Kengo. C4S DB: Comprehensive Collection and Comparison for ChIP-Seq Database. Journal of Molecular Biology. 2023; 435 (14): 168157. doi:10.1016/j.jmb.2023.168157  
101.   Yashima K., Noda A., Ishikawa T., et al. Safety evaluation of the use of calcineurin inhibitor to prenatal and postpartum women in Japan from a health administrative database. Journal of Neonatal-Perinatal Medicine. 2023; 16 (3): 461-473. doi:10.3233/NPM-230138  
102.   YAMAKI Michiko, SAITO Hiroki, MIMORI Takahiro, et al. Analysis of Genetic Polymorphism of Bitter Taste Receptor TAS2R38 and TAS2R46, and Its Relationship with Eating and Drinking Habits in Japanese ToMMo Subjects. Journal of Nutritional Science and Vitaminology. 2023; 69 (5): 347-356. doi:10.3177/jnsv.69.347  
103.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Identification of predictive biomarkers for diagnosis and radiation sensitivity of uterine cervical cancer using wide‐targeted metabolomics. Journal of Obstetrics and Gynaecology Research. 2023; 49 (8): 2109-2117. doi:10.1111/jog.15709  
104.   Takahashi Ippei, Obara Taku, Kikuchi Saya, et al. Association between maternal psychological distress and children's neurodevelopment in offspring aged 4 years in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Journal of Paediatrics and Child Health. 2023; 59 (3): 548-554. doi:10.1111/jpc.16353  
105.   Orui Masatsugu. Disaster and Suicide Prevention Activities: A Literature Review Focused on Suicide-Related Outcomes. Journal of Suicidology. 2023; 18 (2): 518 - 528. doi:10.30126/JoS.202306_18(2).0004  
106.   Ito Tomoyuki, Nguyen Thuy Duong, Saito Yutaka, et al. Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning. mAbs. 2023; 15 (1): . doi:10.1080/19420862.2023.2168470  
107.   Saigusa Daisuke, Saito Ritsumi, Kawamoto Komei, et al. Improving the Signal Intensity of Cryosections Using a Conductive Adhesive Film in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Mass Spectrometry. 2023; 12 (1): A0137. doi:10.5702/massspectrometry.A0137  
108.   Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of Education and Income with Secondhand Smoke Exposure Among Non-smoking Pregnant Women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Maternal and Child Health Journal. 2023; 27 (7): 1238-1246. doi:10.1007/s10995-023-03648-x  
109.   Nakayasu Masaru, Takamatsu Kyoko, Kanai Keiko, et al. Tomato root-associated Sphingobium harbors genes for catabolizing toxic steroidal glycoalkaloids. mBio. 2023; 14 (5): . doi:10.1128/mbio.00599-23  
110.   Yu Zhiqian, Ueno Kazuko, Funayama Ryo, et al. Sex-Specific Differences in the Transcriptome of the Human Dorsolateral Prefrontal Cortex in Schizophrenia. Molecular Neurobiology. 2023; 60 (2): 1083-1098. doi:10.1007/s12035-022-03109-6  
111.   Nishioka Masaki, Takayama Jun, Sakai Naomi, et al. Deep exome sequencing identifies enrichment of deleterious mosaic variants in neurodevelopmental disorder genes and mitochondrial tRNA regions in bipolar disorder. Molecular Psychiatry. 2023; 28 (10): 4294-4306. doi:10.1038/s41380-023-02096-x  
112.   Suzuki Takafumi, Takahashi Jun, Yamamoto Masayuki. Molecular Basis of the KEAP1-NRF2 Signaling Pathway. Molecules and Cells. 2023; 46 (3): 133-141. doi:10.14348/molcells.2023.0028  
113.   Bui Han Ba, Watanabe Satoshi, Nomura Norimichi, et al. Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus. Nature Communications. 2023; 14 (1): 4770. doi:10.1038/s41467-023-40521-5  
114.   Yamaguchi Satoshi, Murakami Takahisa, Satoh Michihiro, et al. Associations of Dental Health With the Progression of Hippocampal Atrophy in Community-Dwelling Individuals. Neurology. 2023; 101 (10): e1056-e1068. doi:10.1212/WNL.0000000000207579  
115.   Sato Kota, Saigusa Daisuke, Kokubun Taiki, et al. Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma. npj Aging. 2023; 9 (1): 28. doi:10.1038/s41514-023-00124-2  
116.   Obayashi Takeshi, Kodate Shun, Hibara Himiko, et al. COXPRESdb v8: an animal gene coexpression database navigating from a global view to detailed investigations. Nucleic Acids Research. 2023; 51 (D1): D80-D87. doi:10.1093/nar/gkac983  
117.   Sakurai Nozomu, Yamazaki Shinichi, Suda Kunihiro, et al. The Thing Metabolome Repository family (XMRs): comparable untargeted metabolome databases for analyzing sample-specific unknown metabolites. Nucleic Acids Research. 2023; 51 (D1): D660-D677. doi:10.1093/nar/gkac1058  
118.   Saito Yoshie, Sato Keigo, Jinno Shinji, et al. Effect of Nicotinamide Mononucleotide Concentration in Human Milk on Neurodevelopmental Outcome: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Nutrients. 2023; 16 (1): 145. doi:10.3390/nu16010145  
119.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Nutrition Journal. 2023; 22 (1): 66. doi:10.1186/s12937-023-00901-5  
120.   Uneoka Saki, Kobayashi Tomoko, Numata-Uematsu Yurika, et al. A Case Series of Patients With MYBPC1 Gene Variants Featuring Undulating Tongue Movements as Myogenic Tremor. Pediatric Neurology. 2023; 146 : 16-20. doi:10.1016/j.pediatrneurol.2023.06.002  
121.   Ogawa Sayaka, Hayashida Masaki, Tayama Jun, et al. Preventive Effects of Group Cognitive Behavioral Therapy in First-Year University Students at Risk for Depression: A Non-Randomized Controlled Trial. Perceptual and Motor Skills. 2023; 130 (2): 790-807. doi:10.1177/00315125231153778  
122.   Matsuda Hinako, Yamazaki Yumi, Moriyoshi Eiko, et al. Apoplast-Localized β-Glucosidase Elevates Isoflavone Accumulation in the Soybean Rhizosphere. Plant And Cell Physiology. 2023; 64 (5): 486-500. doi:10.1093/pcp/pcad012  
123.   Takamatsu Kyoko, Toyofuku Miwako, Okutani Fuki, et al. α‐Tomatine gradient across artificial roots recreates the recruitment of tomato root‐associated Sphingobium. Plant Direct. 2023; 7 (12): . doi:10.1002/pld3.550  
124.   Itoh Naoya, Kawabata Takanori, Akazawa Nana, et al. Reduction strategies for inpatient oral third-generation cephalosporins at a cancer center: An interrupted time-series analysis. PLOS ONE. 2023; 18 (2): e0281518. doi:10.1371/journal.pone.0281518  
125.   Tagami Kazuma, Iwama Noriyuki, Hamada Hirotaka, et al. Maternal birth weight as an indicator of early-onset and late-onset hypertensive disorders of pregnancy: The Japan Environment and Children’s study. Pregnancy Hypertension. 2023; 34 : 159-168. doi:10.1016/j.preghy.2023.11.002  
126.   Ishikawa Tomofumi, Nishigori Hidekazu, Akazawa Manabu, et al. Risk of major congenital malformations associated with first-trimester antihypertensives, including amlodipine and methyldopa: A large claims database study 2010–2019. Pregnancy Hypertension. 2023; 31 : 73-83. doi:10.1016/j.preghy.2023.01.001  
127.   Ono Chiaki T., Yu Zhiqian, Obara Taku, et al. Association between low levels of anti‐inflammatory cytokines during pregnancy and postpartum depression. Psychiatry and Clinical Neurosciences. 2023; 77 (8): 434-441. doi:10.1111/pcn.13566  
128.   Aizawa Misato, Murakami Keiko, Yonezawa Yudai, et al. Associations between sugar-sweetened beverages before and during pregnancy and offspring overweight/obesity in Japanese women: the TMM BirThree Cohort Study. Public Health Nutrition. 2023; 26 (6): 1222-1229. doi:10.1017/S1368980023000307  
129.   Baird Liam, Taguchi Keiko, Zhang Anqi, et al. A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells. Redox Biology. 2023; 66 : 102845. doi:10.1016/j.redox.2023.102845  
130.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Infertility Treatment and Hypertension in Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Reproductive Medicine. 2023; 4 (2): 89-99. doi:10.3390/reprodmed4020010  
131.   Ohe Takashi, Yamada Mitsuhiro, Hozawa Atsushi, et al. Associations between birth weight and lung function in a Japanese adult population: The tohoku medical megabank community-based cohort study. Respiratory Investigation. 2023; 61 (5): 588-600. doi:10.1016/j.resinv.2023.06.004  
132.   Shiga Hisashi, Takahashi Takahiro, Shiraki Manabu, et al. Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents. Scandinavian Journal of Gastroenterology. 2023; 58 (4): 360-367. doi:10.1080/00365521.2022.2132831  
133.   Seo Kanako, Takayanagi Naoto, Sudo Motoki, et al. Association between daily gait speed patterns and cognitive impairment in community-dwelling older adults. Scientific Reports. 2023; 13 (1): 2783. doi:10.1038/s41598-023-29805-4  
134.   Furukawa Yoshihiro, Saigusa Daisuke, Kano Kuniyuki, et al. Distributions of CHN compounds in meteorites record organic syntheses in the early solar system. Scientific Reports. 2023; 13 (1): 6683. doi:10.1038/s41598-023-33595-0  
135.   Hanyuda Akiko, Goto Atsushi, Katagiri Ryoko, et al. Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation. Scientific Reports. 2023; 13 (1): 7052. doi:10.1038/s41598-023-33966-7  
136.   Suzuki Tetsuya, Morioka Shinichiro, Yamamoto Kei, et al. Nasopharyngeal SARS-CoV-2 may not be dispersed by a high-flow nasal cannula. Scientific Reports. 2023; 13 (1): 2669. doi:10.1038/s41598-023-29740-4  
137.   Satoh Michihiro, Yoshida Tomoya, Metoki Hirohito, et al. The long-term reproducibility of the white-coat effect on blood pressure as a continuous variable from the Ohasama Study. Scientific Reports. 2023; 13 (1): 4985. doi:10.1038/s41598-023-31861-9  
138.   Akaishi Tetsuya, Misu Tatsuro, Fujihara Kazuo, et al. White blood cell count profiles in anti-aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder and anti-myelin oligodendrocyte glycoprotein antibody-associated disease. Scientific Reports. 2023; 13 (1): 6481. doi:10.1038/s41598-023-33827-3  
139.   Akiyama Mari, Akiyama Tomoyuki, Saigusa Daisuke, et al. Comprehensive study of metabolic changes induced by a ketogenic diet therapy using GC/MS- and LC/MS-based metabolomics. Seizure: European Journal of Epilepsy. 2023; 107 : 52-59. doi:10.1016/j.seizure.2023.03.014  
140.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal social isolation in the perinatal period and early childhood development: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Social Psychiatry and Psychiatric Epidemiology. 2023; 58 (11): 1593-1601. doi:10.1007/s00127-023-02498-w  
141.   Mori Naoko, Mugikura Shunji, Takase Kei. The role of magnetic resonance imaging in prostate cancer patients on active surveillance. The British Journal of Radiology. 2023; 96 (1151): . doi:10.1259/bjr.20220140  
142.   Ohseto Hisashi, Ishikuro Mami, Obara Taku, et al. Dietary calcium intake was related to the onset of pre‐eclampsia: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2023; 25 (1): 61-70. doi:10.1111/jch.14606  
143.   Nanatani Kei, Ishii Tomoko, Masuda Ayumu, et al. Novel transporter screening technology for chemical production by microbial fermentation. The Journal of General and Applied Microbiology. 2023; 69 (3): 2022.12.002. doi:10.2323/jgam.2022.12.002  
144.   Kobayashi Tomoko, Kobayashi Mika, Minegishi Naoko, et al. Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2023; 259 (2): 2022.J103. doi:10.1620/tjem.2022.J103  
145.   Shao Xiaodong, Saito Ryuta, Sato Aya, et al. Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study. The Tohoku Journal of Experimental Medicine. 2023; 261 (3): 2023.J069. doi:10.1620/tjem.2023.J069  
146.   Sasano Mina, Hayashi Hironori, Kawaji Kumi, et al. Establishing an accurate and sensitive in vitro drug screening system for human adenovirus infection with human corneal cells. Virology. 2023; 581 : 34-38. doi:10.1016/j.virol.2023.02.005  
147.   陽子 泉. 個別化医療の現状と、 職場における遺伝情報の事例検討. 産業保健法学会誌. 2023; 2 (1): 101-107. doi:10.57523/jaohl.2.1_101  
148.   陽子 泉, 高志 菰口, 昌幸 立道, 丈典 三柴. 職場におけるがん検診推進の背景と課題～法定外健康情報の取扱いの適正化へ向けた序論～. 産業保健法学会誌. 2023; 2 (2): 21-32. doi:10.57523/jaohl.2.2_21  
149.   小暮真奈, 寳澤篤. ナトリウム/カリウム（Na/K）比に関する知見と今後の展開. 日本循環器病予防学会誌. 2023; 58 (1): 22-30.