Tohoku University Tohoku Medical Megabank Organization (2021)
2022.08.12

1.   Ren Hainan, Mori Naoko, Mugikura Shunji, et al. Prediction of placenta accreta spectrum using texture analysis on coronal and sagittal T2-weighted imaging. Abdominal Radiology. 2021; 46 (11): 5344-5352. doi:10.1007/s00261-021-03226-1  
2.   Wada Riho, Fujiwara Masaki, Yamada Yuto, et al. Validity and Reliability of the Japanese Version of the 12-item Self-administered World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in Patients with Schizophrenia. Acta medica Okayama. 2021; 75 (3): 315-322. doi:10.18926/AMO/62226  
3.   Shimoda Yoshiteru, Kanamori Masayuki, Saito Ryuta, et al. Aphasic status epilepticus after glioma resection: two case reports. Acta Neurochirurgica. 2021; 163 (11): 3109-3113. doi:10.1007/s00701-021-04984-z  
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5.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Maternal personality and alcohol use during pregnancy in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Addictive Behaviors. 2021; 122 : 107020. doi:10.1016/j.addbeh.2021.107020  
6.   Zempo Hirofumi, Kim Su-Jeong, Fuku Noriyuki, et al. A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c. Aging. 2021; 13 (2): 1692-1717. doi:10.18632/aging.202529  
7.   Kittikulsuth Wararat, Nakano Daisuke, Kitada Kento, et al. Renal NG2-expressing cells have a macrophage-like phenotype and facilitate renal recovery after ischemic injury. American Journal of Physiology-Renal Physiology. 2021; 321 (2): F170-F178. doi:10.1152/ajprenal.00011.2021  
8.   Kano Kuniyuki, Aoki Junken, Iwama Taiga, et al. Development of an on-tissue derivatization method for MALDI mass spectrometry imaging of bioactive lipids containing phosphate monoester using Phos-Tag. Analytical Chemistry. 2021; 93 (8): 3867-3875. doi:10.1021/acs.analchem.0c04479  
9.   Yamashita Takahiro, Murakami Keiko, Obara Taku, et al. Living environments long-term after the Great East Japan Earthquake and nutritional intake among recent mothers. Asia Pacific journal of clinical nutrition. 2021; 30 (4): 651-661. doi:10.6133/apjcn.202112_30(4).0012  
10.   Kikuchi Daisuke, Obara Taku, Tokunaga Misaki, et al. Drug prescription for attention deficit hyperactivity disorder drugs in pediatric outpatients: A retrospective survey of Japanese administrative data (2012–2018). Asian Journal of Psychiatry. 2021; 57 : 102512. doi:10.1016/j.ajp.2020.102512  
11.   Sasaki Ai, Nakao Yuki, Obara Taku, et al. Knowledge and Attitude towards Cervical Cancer and Human Papillomavirus among Pharmacists in Japan. Asian Pacific Journal of Cancer Prevention. 2021; 22 (7): 2259-2265. doi:10.31557/APJCP.2021.22.7.2259  
12.   Nakayama Shingo, Satoh Michihiro, Tatsumi Yukako, et al. Detailed association between serum uric acid levels and the incidence of chronic kidney disease stratified by sex in middle-aged adults. Atherosclerosis. 2021; 330 : 107-113. doi:10.1016/j.atherosclerosis.2021.06.908  
13.   Nakaya Naoki, Xie Tian, Scheerder Bart, et al. Spousal similarities in cardiometabolic risk factors: A cross-sectional comparison between Dutch and Japanese data from two large biobank studies. Atherosclerosis. 2021; 334 : 85-92. doi:10.1016/j.atherosclerosis.2021.08.037  
14.   Tayama Hodaka, Karasawa Hideaki, Yamamura Akihiro, et al. The association between ERK inhibitor sensitivity and molecular characteristics in colorectal cancer. Biochemical and Biophysical Research Communications. 2021; 560 : 59-65. doi:10.1016/j.bbrc.2021.04.130  
15.   Uchida Yasuo, Higuchi Tomoya, Shirota Matsuyuki, et al. Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia. Biological and Pharmaceutical Bulletin. 2021; 44 (6): 804-815. doi:10.1248/bpb.b20-01043  
16.   Yu Lei, Myers Greggory, Ku Chia-Jui, et al. An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation. Blood. 2021; 138 (18): 1691-1704. doi:10.1182/blood.2021011682  
17.   Seki Yumika, Ishizawa Kota, Akaishi Tetsuya, et al. Retrospective study revealed that Zn relate to improvement of swallowing function in the older adults. BMC Geriatrics. 2021; 21 (1): 279. doi:10.1186/s12877-021-02224-8  
18.   Kotozaki Yuka, Tanno Kozo, Sakata Kiyomi, et al. Association between the social isolation and depressive symptoms after the great East Japan earthquake: findings from the baseline survey of the TMM CommCohort study. BMC Public Health. 2021; 21 (1): 925. doi:10.1186/s12889-021-10896-5  
19.   Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of education and work status with alcohol use and cessation among pregnant women in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Public Health. 2021; 21 (1): 1400. doi:10.1186/s12889-021-11461-w  
20.   Mizukami Miyako, Ishikawa Aki, Miyazaki Sachiko, et al. A de novo CHD3 variant in a child with intellectual disability, autism, joint laxity, and dysmorphisms. Brain and Development. 2021; 43 (4): 563-565. doi:10.1016/j.braindev.2020.12.004  
21.   Mugikura Shunji, Mori Naoko, Takahashi Shoki. Serial changes of T1-, T2-weighted MR imaging and MR spectroscopy in Tay-Sachs disease with late onset spasms. Brain and Development. 2021; 43 (9): 975-976. doi:10.1016/j.braindev.2021.06.009  
22.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. General Intelligence Is Associated with Working Memory-Related Functional Connectivity Change: Evidence from a Large-Sample Study. Brain Connectivity. 2021; 11 (2): 89-102. doi:10.1089/brain.2020.0769  
23.   Takeuchi Hikaru, Maruyama Tsukasa, Taki Yasuyuki, et al. Effects of training of shadowing and reading aloud of second language on working memory and neural systems. Brain Imaging and Behavior. 2021; 15 (3): 1253-1269. doi:10.1007/s11682-020-00324-4  
24.   Mori Naoko, Abe Hiroyuki, Mugikura Shunji, et al. Discriminating low-grade ductal carcinoma in situ (DCIS) from non-low-grade DCIS or DCIS upgraded to invasive carcinoma: effective texture features on ultrafast dynamic contrast-enhanced magnetic resonance imaging. Breast Cancer. 2021; 28 (5): 1141-1153. doi:10.1007/s12282-021-01257-6  
25.   Yashima Kazushi, Obara Taku, Matsuzaki Fumiko, et al. Evaluation of the Safety of Taking Lamotrigine During Lactation Period. Breastfeeding Medicine. 2021; 16 (5): 432-438. doi:10.1089/bfm.2020.0210  
26.   Suzuki Taro, Nakamura Yasuyuki, Doi Yukio, et al. A genome-wide association study on confection consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort Study. British Journal of Nutrition. 2021; 126 (12): 1843-1851. doi:10.1017/S0007114521000684  
27.   Nishimoto Yuka, Tsubono Yoshitaka, Kogure Mana, et al. The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community‐based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally repres. Cancer Medicine. 2021; 10 (24): 9000-9011. doi:10.1002/cam4.4364  
28.   Suzuki Shiori, Goto Atsushi, Nakatochi Masahiro, et al. Body mass index and colorectal cancer risk: A Mendelian randomization study. Cancer Science. 2021; 112 (4): 1579-1588. doi:10.1111/cas.14824  
29.   Kanazawa Kosuke, Kishimoto Kazuhiro, Nomura Miyuki, et al. Ppp6c haploinsufficiency accelerates UV‐induced BRAF(V600E)‐initiated melanomagenesis. Cancer Science. 2021; 112 (6): 2233-2244. doi:10.1111/cas.14895  
30.   Yamauchi Takuro, Fujishima Fumiyoshi, Hashimoto Masatoshi, et al. Necroptosis in Esophageal Squamous Cell Carcinoma: An Independent Prognostic Factor and Its Correlation with Tumor-Infiltrating Lymphocytes. Cancers. 2021; 13 (17): 4473. doi:10.3390/cancers13174473  
31.   Rehm Heidi L., Page Angela J.H., Smith Lindsay, et al. GA4GH: International policies and standards for data sharing across genomic research and healthcare. Cell Genomics. 2021; 1 (2): 100029. doi:10.1016/j.xgen.2021.100029  
32.   Lawson Jonathan, Cabili Moran N., Kerry Giselle, et al. The Data Use Ontology to streamline responsible access to human biomedical datasets. Cell Genomics. 2021; 1 (2): 100028. doi:10.1016/j.xgen.2021.100028  
33.   Usami Katsuki, Niimi Kanae, Matsuo Ayumi, et al. The gut microbiota induces Peyer’s-patch-dependent secretion of maternal IgA into milk. Cell Reports. 2021; 36 (10): 109655. doi:10.1016/j.celrep.2021.109655  
34.   Omori Satoshi, Tsugita Misato, Hoshikawa Yasuto, et al. Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation. Cell Reports. 2021; 34 (6): 108734. doi:10.1016/j.celrep.2021.108734  
35.   Chiba Yuki, Nagasawa Tasuku, Kin Saori, et al. Spontaneous remission of minimal change nephrotic syndrome in an elderly man. CEN Case Reports. 2021; 10 (2): 301-307. doi:10.1007/s13730-020-00554-x  
36.   Takeuchi Hikaru, Tomita Hiroaki, Browne Ryan, et al. Sex-Dependent Effects of the APOE ɛ4 Allele on Behavioral Traits and White Matter Structures in Young Adults. Cerebral Cortex. 2021; 31 (1): 672-680. doi:10.1093/cercor/bhaa251  
37.   von Scheidt Moritz, Zhao Yuqi, de Aguiar Vallim Thomas Q., et al. Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. Circulation. 2021; 143 (18): 1809-1823. doi:10.1161/CIRCULATIONAHA.120.050186  
38.   Takase Masato, Nakamura Tomohiro, Tsuchiya Naho, et al. Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study. Clinical and Experimental Hypertension. 2021; 43 (7): 610-621. doi:10.1080/10641963.2021.1925681  
39.   Takeuchi Hikaru, Taki Yasuyuki, Asano Kohei, et al. Childhood socioeconomic status is associated with psychometric intelligence and microstructural brain development. Communications Biology. 2021; 4 (1): 470. doi:10.1038/s42003-021-01974-w  
40.   Yamada Mitsuhiro, Motoike Ikuko N., Kojima Kaname, et al. Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator. Communications Biology. 2021; 4 (1): 1288. doi:10.1038/s42003-021-02813-8  
41.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Lead exposure is associated with functional and microstructural changes in the healthy human brain. Communications Biology. 2021; 4 (1): 912. doi:10.1038/s42003-021-02435-0  
42.   Horie Yuta, Suzuki Takafumi, Inoue Jin, et al. Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism. Communications Biology. 2021; 4 (1): 576. doi:10.1038/s42003-021-02100-6  
43.   Uruno Akira, Saigusa Daisuke, Suzuki Takafumi, et al. Nrf2 plays a critical role in the metabolic response during and after spaceflight. Communications Biology. 2021; 4 (1): 1381. doi:10.1038/s42003-021-02904-6  
44.   Orui Masatsugu, Saeki Suzuka, Kozakai Yuki, et al. The Impact of the COVID-19 Pandemic on Suicide Rate Trends in the Tsunami-Disaster-Affected Area Following the Great East Japan Earthquake. Crisis. 2021; : . doi:10.1027/0227-5910/a000832  
45.   Kikuchi Saya, Kobayashi Natsuko, Watanabe Zen, et al. The delivery of a placenta/fetus with high gonadal steroid production contributes to postpartum depressive symptoms. Depression and Anxiety. 2021; 38 (4): 422-430. doi:10.1002/da.23134  
46.   Nishimura Tamako, Oyama Takuya, Hu Hooi Ting, et al. Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells. Developmental Cell. 2021; 56 (6): 842-859.e8. doi:10.1016/j.devcel.2021.02.029  
47.   Norita Kazuaki, Asanuma Kiyotaka, Koike Tomoyuki, et al. Impaired Mucosal Integrity in Proximal Esophagus Is Involved in Development of Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease. Digestion. 2021; 102 (3): 404-414. doi:10.1159/000508661  
48.   Akaishi Tetsuya, Suzuki Tomomi, Nemoto Harumi, et al. Five-Year Psychosocial Impact of Living in Postdisaster Prefabricated Temporary Housing. Disaster Medicine and Public Health Preparedness. 2021; : 1-9. doi:10.1017/dmp.2021.214  
49.   Hayashi Takuo, Odintsov Igor, Smith Roger S., et al. RET inhibition in novel patient-derived models of RET fusion- positive lung adenocarcinoma reveals a role for MYC upregulation. Disease Models & Mechanisms. 2021; 14 (2): . doi:10.1242/dmm.047779  
50.   Kumondai Masaki, Gutiérrez Rico Evelyn Marie, Hishinuma Eiji, et al. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6 β -Hydroxylation. Drug Metabolism and Disposition. 2021; 49 (3): 212-220. doi:10.1124/dmd.120.000261  
51.   Shimizu Makiko, Koibuchi Natsumi, Mizugaki Ami, et al. Genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects identified by phenotyping for trimethylaminuria and found in a database of genome resources. Drug Metabolism and Pharmacokinetics. 2021; 38 : 100387. doi:10.1016/j.dmpk.2021.100387  
52.   Saigusa Daisuke, Matsukawa Naomi, Hishinuma Eiji, Koshiba Seizo. Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics. Drug Metabolism and Pharmacokinetics. 2021; 37 : 100373. doi:10.1016/j.dmpk.2020.11.008  
53.   Miyauchi Kenichiro, Nakai Taku, Saito Sakae, et al. Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions. EBioMedicine. 2021; 64 : 103209. doi:10.1016/j.ebiom.2021.103209  
54.   Evangelou Evangelos, Suzuki Hideaki, Bai Wenjia, et al. Alcohol consumption in the general population is associated with structural changes in multiple organ systems. eLife. 2021; 10 : . doi:10.7554/eLife.65325  
55.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Associations of education and income with hazardous drinking among postpartum women in Japan: results from the TMM BirThree Cohort Study. Environmental Health and Preventive Medicine. 2021; 26 (1): 70. doi:10.1186/s12199-021-00991-9  
56.   Tanoue Kaou, Watanabe Zen, Nishigori Hidekazu, et al. The prevalence of psychological distress during pregnancy in Miyagi Prefecture for 3 years after the Great Eas t Japan Earthquake. Environmental Health and Preventive Medicine. 2021; 26 (1): 27. doi:10.1186/s12199-021-00944-2  
57.   Kikuchi Daisuke, Obara Taku, Kashiwagura Shota, et al. Trends in prescription of anti-seizure medicines for Japanese pediatric outpatients during 2013–2019. Epilepsy & Behavior Reports. 2021; 16 : 100474. doi:10.1016/j.ebr.2021.100474  
58.   Suzuki Hideaki, Yasuda Satoshi, Shimokawa Hiroaki. Brain–heart connection in Takotsubo syndrome before onset. European Heart Journal. 2021; 42 (19): 1909-1911. doi:10.1093/eurheartj/ehab026  
59.   Shiihara Masahiro, Ishikawa Tomohiko, Saiki Yuriko, et al. Development of a system combining comprehensive genotyping and organoid cultures for identifying and testing genotype-oriented personalised medicine for pancreatobiliary cancers. European Journal of Cancer. 2021; 148 : 239-250. doi:10.1016/j.ejca.2021.01.047  
60.   Suzuki Harumitsu, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern. European Journal of Clinical Nutrition. 2021; 75 (6): 937-945. doi:10.1038/s41430-020-00823-z  
61.   Suzuki Taro, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study on fish consumption in a Japanese population—the Japan Multi-Institutional Collaborative Cohort study. European Journal of Clinical Nutrition. 2021; 75 (3): 480-488. doi:10.1038/s41430-020-00702-7  
62.   Gervais Olivier, Ueno Kazuko, Kawai Yosuke, et al. Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population. European Journal of Human Genetics. 2021; 29 (8): 1282-1291. doi:10.1038/s41431-021-00854-5  
63.   Mori Naoko, Mugikura Shunji, Takase Kei. Importance of ADC parameters from histogram analysis corresponding to histological components in endometrial cancer. European Journal of Radiology. 2021; 144 : 110004. doi:10.1016/j.ejrad.2021.110004  
64.   Kageyama Sakiko, Mori Naoko, Mugikura Shunji, et al. Gaussian mixture model-based cluster analysis of apparent diffusion coefficient values: a novel approach to evaluate uterine endometrioid carcinoma grade. European Radiology. 2021; 31 (1): 55-64. doi:10.1007/s00330-020-07047-6  
65.   Yumoto Akane, Kokubo Toshiaki, Izumi Ryutaro, et al. Novel method for evaluating the health condition of mice in space through a video downlink. Experimental Animals. 2021; 70 (2): 236-244. doi:10.1538/expanim.20-0102  
66.   Hamanaka Teruhiko, Sakurai Tetsuro, Fuse Nobuo, et al. Comparisons of Schlemm's canal and trabecular meshwork morphologies between juvenile and primary open angle glaucoma. Experimental Eye Research. 2021; 210 : 108711. doi:10.1016/j.exer.2021.108711  
67.   Saito Sakae, Aoki Yuichi, Tamahara Toru, et al. Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project. Frontiers in Cellular and Infection Microbiology. 2021; 10 : . doi:10.3389/fcimb.2020.604596  
68.   Mardani-Korrani Hossein, Nakayasu Masaru, Yamazaki Shinichi, et al. L-Canavanine, a Root Exudate From Hairy Vetch (Vicia villosa) Drastically Affecting the Soil Microbial Community and Metabolite Pathways. Frontiers in Microbiology. 2021; 12 : . doi:10.3389/fmicb.2021.701796  
69.   Suzuki Satoko, Obara Taku, Ishikawa Tomofumi, et al. Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database. Frontiers in Nutrition. 2021; 8 : . doi:10.3389/fnut.2021.762895  
70.   Imamura Tadatsugu, Saito Mayuko, Ko Yura K., et al. Roles of Children and Adolescents in COVID-19 Transmission in the Community: A Retrospective Analysis of Nationwide Data in Japan. Frontiers in Pediatrics. 2021; 9 : . doi:10.3389/fped.2021.705882  
71.   Komatsu Hiroshi, Takeuchi Hikaru, Ono Chiaki, et al. Association Between OLIG2 Gene SNP rs1059004 and Negative Self-Schema Constructing Trait Factors Underlying Susceptibility to Depression. Frontiers in Psychiatry. 2021; 12 : . doi:10.3389/fpsyt.2021.631475  
72.   Tajima Kentaro, Tsuchiya Masami, Ishikawa Tomofumi, et al. Real-world anticancer medications for reproductive-age women with breast cancer by using a claims database in Japan. Future Oncology. 2021; 17 (15): 1907-1921. doi:10.2217/fon-2020-1053  
73.   Ueki Masao, Tamiya Gen. Smooth-threshold multivariate genetic prediction incorporating gene–environment interactions. G3 Genes|Genomes|Genetics. 2021; 11 (12): . doi:10.1093/g3journal/jkab278  
74.   Isaka Yuichi, Nishio Shin-ya, Hishinuma Eiji, et al. Improvement of a Rapid and Highly Sensitive Method for the Diagnosis of the Mitochondrial m.1555A>G Mutation Based on a Single-Stranded Tag Hybridization Chromatographic Printed-Array Strip. Genetic Testing and Molecular Biomarkers. 2021; 25 (1): 79-83. doi:10.1089/gtmb.2020.0105  
75.   Hatta Waku, Tsuji Yosuke, Yoshio Toshiyuki, et al. Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score. Gut. 2021; 70 (3): 476-484. doi:10.1136/gutjnl-2019-319926  
76.   Hidaka Hiroshi, Tarasawa Kunio, Fujimori Kenji, et al. Identification of risk factors for mortality and delayed oral dietary intake in patients with open drainage due to deep neck infections: Nationwide study using a Japanese inpatient database. Head & Neck. 2021; 43 (7): 2002-2012. doi:10.1002/hed.26660  
77.   Fukunaga Hisanori, Ogawa Tsubasa, Asano Tomohiro, Ito Atsuo. Radiation Exposure Dose Distribution of Workers Engaged in Decontamination and Related Work Following the Fukushima Nuclear Disaster. Health Physics. 2021; 120 (3): 251-257. doi:10.1097/HP.0000000000001309  
78.   Kobayashi Tomonori, Noda Aoi, Obara Taku, et al. Knowledge, Attitudes, and Practice of Hospital Pharmacists Regarding Pharmacovigilance and Adverse Drug Reaction Reporting in Japan. Hospital Pharmacy. 2021; 56 (1): 7-16. doi:10.1177/0018578719851455  
79.   Takeuchi Hikaru, Kimura Ryosuke, Tomita Hiroaki, et al. Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex. Human Brain Mapping. 2021; 42 (18): 6028-6037. doi:10.1002/hbm.25667  
80.   Ogishima Soichi, Nagaie Satoshi, Mizuno Satoshi, et al. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Human Genome Variation. 2021; 8 (1): 44. doi:10.1038/s41439-021-00175-5  
81.   Nagaoka Shinichi, Yamaguchi-Kabata Yumi, Shiga Naomi, et al. Estimation of the carrier frequencies and proportions of potential patients by detecting causative gene variants associated with autosomal recessive bone dysplasia using a whole-genome reference panel of Japanese individuals. Human Genome Variation. 2021; 8 (1): 2. doi:10.1038/s41439-020-00133-7  
82.   Miyazaki Makoto, Obara Taku, Mano Nariyasu. Impact of local vaccine subsidization programs on the prevention of mumps in Japan. Human Vaccines & Immunotherapeutics. 2021; 17 (11): 4216-4224. doi:10.1080/21645515.2021.1974797  
83.   Kadowaki Sayaka, Kadowaki Takashi, Hozawa Atsushi, et al. Differences between home blood pressure and strictly measured office blood pressure and their determinants in Japanese men. Hypertension Research. 2021; 44 (1): 80-87. doi:10.1038/s41440-020-00533-w  
84.   Hirata Takumi, Kogure Mana, Tsuchiya Naho, et al. Impacts of the urinary sodium-to-potassium ratio, sleep efficiency, and conventional risk factors on home hypertension in a general Japanese population. Hypertension Research. 2021; 44 (7): 858-865. doi:10.1038/s41440-021-00628-y  
85.   Nakayama Shingo, Satoh Michihiro, Metoki Hirohito, et al. Lifetime risk of stroke stratified by chronic kidney disease and hypertension in the general Asian population: the Ohasama study. Hypertension Research. 2021; 44 (7): 866-873. doi:10.1038/s41440-021-00635-z  
86.   Kikuchi Daisuke, Ito Misato, Tokunaga Misaki, et al. Prescription status of diuretics for essential hypertension in a Japanese population. Hypertension Research. 2021; 44 (10): 1359-1361. doi:10.1038/s41440-021-00688-0  
87.   Kogure Mana, Nakaya Naoki, Hirata Takumi, et al. Sodium/potassium ratio change was associated with blood pressure change: possibility of population approach for sodium/potassium ratio reduction in health checkup. Hypertension Research. 2021; 44 (2): 225-231. doi:10.1038/s41440-020-00536-7  
88.   Oe Yuji, Mishima Eikan, Mori Takayasu, et al. A Novel Mutation in LMX1B (p.Pro219Ala) Causes Focal Segmental Glomerulosclerosis with Alport Syndrome-like Phenotype. Internal Medicine. 2021; 60 (18): 6987-20. doi:10.2169/internalmedicine.6987-20  
89.   Hakamata Mariko, Hokari Satoshi, Ohshima Yasuyoshi, et al. Chronic Hypercapnic Respiratory Failure in an Adult Patient with Silver-Russell Syndrome. Internal Medicine. 2021; 60 (12): 1921-1926. doi:10.2169/internalmedicine.5479-20  
90.   Saito Masahiro, Koike Tomoyuki, Abe Yasuaki, et al. The Development of Foveolar-type Gastric Adenocarcinoma during Maintenance Therapy of Vonoprazan for Reflux Esophagitis. Internal Medicine. 2021; 60 (3): 391-396. doi:10.2169/internalmedicine.5431-20  
91.   Usuzaki Takuma, Chiba Shuji, Shimoyama Minoru, et al. A disparity in the number of studies related to COVID-19 and SARS-CoV-2 between low- and middle-income countries and high-income countries. International Health. 2021; 13 (4): 379-381. doi:10.1093/inthealth/ihaa088  
92.   Suzuki Hideaki, Takanami Kentaro, Takase Kei, et al. Reversible increase in stress-associated neurobiological activity in the acute phase of Takotsubo syndrome; a brain 18F-FDG-PET study. International Journal of Cardiology. 2021; 344 : 31-33. doi:10.1016/j.ijcard.2021.09.057  
93.   Kato Koichi, Nakayoshi Tomoki, Nokura Rika, et al. Deciphering Structural Alterations Associated with Activity Reductions of Genetic Polymorphisms in Cytochrome P450 2A6 Using Molecular Dynamics Simulations. International Journal of Molecular Sciences. 2021; 22 (18): 10119. doi:10.3390/ijms221810119  
94.   Kikuchi Atsuo, Wada Yoichi, Ohura Toshihiro, Kure Shigeo. The Discovery of GALM Deficiency (Type IV Galactosemia) and Newborn Screening System for Galactosemia in Japan. International Journal of Neonatal Screening. 2021; 7 (4): 68. doi:10.3390/ijns7040068  
95.   Mori Naoko, Mugikura Shunji, Takase Kei. Assessment of the sequential time–signal enhancement curve of dynamic contrast-enhanced MRI might be effective in diagnosing growth hormone-producing pituitary adenomas. Japanese Journal of Radiology. 2021; 39 (9): 923-924. doi:10.1007/s11604-021-01146-0  
96.   Mori Naoko, Mugikura Shunji, Takase Kei. Indication of perfusion contrast-enhanced ultrasound for diagnosing lymph nodes. Japanese Journal of Radiology. 2021; 39 (10): 1017-1018. doi:10.1007/s11604-021-01160-2  
97.   Kato Erina, Mori Naoko, Mugikura Shunji, et al. Value of ultrafast and standard dynamic contrast-enhanced magnetic resonance imaging in the evaluation of the presence and extension of residual disease after neoadjuvant chemotherapy in breast cancer. Japanese Journal of Radiology. 2021; 39 (8): 791-801. doi:10.1007/s11604-021-01110-y  
98.   Metoki Hirohito. The Significance of Observing the Risk of Non-communicable Diseases after Large-scale Disasters and Communicable Disease Epidemics. JMA Journal. 2021; 4 (4): . doi:10.31662/jmaj.2021-0126  
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