Tohoku University Tohoku Medical Megabank Organization (2020)
2021.03.05

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6.   Nakagawara Kohsuke, Hayashi Hironori, Kawaji Kumi, et al. Application of human lymphoid cells for the evaluation of antivirals against human adenovirus type 19: Zalcitabine has superior activity compared to cidofovir. Antiviral Chemistry and Chemotherapy. 2020; 28 : 204020662092131. doi:10.1177/2040206620921319  
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9.   Sato Emiko, Hosomi Koji, Sekimoto Akiyo, et al. Effects of the oral adsorbent AST-120 on fecal p-cresol and indole levels and on the gut microbiota composition. Biochemical and Biophysical Research Communications. 2020; 525 (3): 773-779. doi:10.1016/j.bbrc.2020.02.141  
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13.   Anzawa Hayato, Yamagata Hitoshi, Kinoshita Kengo. Theoretical characterisation of strand cross-correlation in ChIP-seq. BMC Bioinformatics. 2020; 21 (1): 417. doi:10.1186/s12859-020-03729-6  
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15.   Noda Aoi, Sakai Takamasa, Obara Taku, et al. Characteristics of pediatric adverse drug reaction reports in the Japanese Adverse Drug Event Report Database. BMC Pharmacology and Toxicology. 2020; 21 (1): 36. doi:10.1186/s40360-020-00412-7  
16.   Mizukami Miyako, Ishikawa Aki, Miyazaki Sachiko, et al. A de novo CHD3 variant in a child with intellectual disability, autism, joint laxity, and dysmorphisms. Brain and Development. 2020; : . doi:10.1016/j.braindev.2020.12.004  
17.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. Effect of the interaction between BDNF Val66Met polymorphism and daily physical activity on mean diffusivity. Brain Imaging and Behavior. 2020; 14 (3): 806-820. doi:10.1007/s11682-018-0025-8  
18.   Takeuchi Hikaru, Maruyama Tsukasa, Taki Yasuyuki, et al. Effects of training of shadowing and reading aloud of second language on working memory and neural systems. Brain Imaging and Behavior. 2020; : . doi:10.1007/s11682-020-00324-4  
19.   Ishii Hiroki, Saitoh Masao, Sakamoto Kaname, et al. Lipidome-based rapid diagnosis with machine learning for detection of TGF-β signalling activated area in head and neck cancer. British Journal of Cancer. 2020; 122 (7): 995-1004. doi:10.1038/s41416-020-0732-y  
20.   Hayashi Makiko, Kuga Ayumi, Suzuki Mikiko, et al. Microenvironmental Activation of Nrf2 Restricts the Progression of Nrf2-Activated Malignant Tumors. Cancer Research. 2020; 80 (16): 3331-3344. doi:10.1158/0008-5472.CAN-19-2888  
21.   Saigusa Daisuke, Motoike Ikuko N., Saito Sakae, et al. Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites. Cancer Science. 2020; 111 (2): 667-678. doi:10.1111/cas.14278  
22.   Yokose Takahiro, Kabe Yasuaki, Matsuda Atsushi, et al. O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer. Cancers. 2020; 12 (9): 2469. doi:10.3390/cancers12092469  
23.   Taguchi Keiko, Yamamoto Masayuki. The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment. Cancers. 2020; 13 (1): 46. doi:10.3390/cancers13010046  
24.   Afshinnekoo Ebrahim, Scott Ryan T., MacKay Matthew J., et al. Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration. Cell. 2020; 183 (5): 1162-1184. doi:10.1016/j.cell.2020.10.050  
25.   Matsunaga Hiroshi, Ito Kaoru, Akiyama Masato, et al. Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease. Circulation: Genomic and Precision Medicine. 2020; 13 (3): . doi:10.1161/CIRCGEN.119.002670  
26.   Noda Aoi, Obara Taku, Takada Kazuki, et al. Changes in community pharmacists’ knowledge, attitudes, and practice regarding the management of hypertension before and after educational interventions. Clinical and Experimental Hypertension. 2020; 42 (4): 322-327. doi:10.1080/10641963.2019.1652634  
27.   Noda Aoi, Obara Taku, Abe Shinya, et al. The present situation of home blood pressure measurement among outpatients in Japan. Clinical and Experimental Hypertension. 2020; 42 (1): 67-74. doi:10.1080/10641963.2019.1571601  
28.   Okuda Hiroshi, Okamoto Koji, Abe Michiaki, et al. Genome-wide association study identifies new loci for albuminuria in the Japanese population. Clinical and Experimental Nephrology. 2020; 24 (8): 1-9. doi:10.1007/s10157-020-01884-x  
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30.   Shibayama Yuki, Takahashi Kazuo, Yamaguchi Hisateru, et al. Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H. Communications Biology. 2020; 3 (1): 724. doi:10.1038/s42003-020-01434-x  
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32.   Suzuki Takafumi, Uruno Akira, Yumoto Akane, et al. Nrf2 contributes to the weight gain of mice during space travel. Communications Biology. 2020; 3 (1): 496. doi:10.1038/s42003-020-01227-2  
33.   Iwama Noriyuki, Sugiyama Takashi, Metoki Hirohito, et al. Associations between glycosylated hemoglobin level at less than 24 weeks of gestation and adverse pregnancy outcomes in Japan: The Japan Environment and Children’s Study (JECS). Diabetes Research and Clinical Practice. 2020; 169 : 108377. doi:10.1016/j.diabres.2020.108377  
34.   Norita Kazuaki, Asanuma Kiyotaka, Koike Tomoyuki, et al. Impaired Mucosal Integrity in Proximal Esophagus Is Involved in Development of Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease. Digestion. 2020; : 1-11. doi:10.1159/000508661  
35.   Gutiérrez Rico Evelyn Marie, Kikuchi Aoi, Saito Takahiro, et al. CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity. Drug Metabolism and Pharmacokinetics. 2020; 35 (1): 89-101. doi:10.1016/j.dmpk.2019.07.003  
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37.   Trivisano Marina, Ferretti Alessandro, Bebin Elizabeth, et al. Defining the phenotype of FHF1 developmental and epileptic encephalopathy. Epilepsia. 2020; 61 (7): . doi:10.1111/epi.16582  
38.   Suzuki Harumitsu, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern. European Journal of Clinical Nutrition. 2020; : . doi:10.1038/s41430-020-00823-z  
39.   Suzuki Taro, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study on fish consumption in a Japanese population—the Japan Multi-Institutional Collaborative Cohort study. European Journal of Clinical Nutrition. 2020; : . doi:10.1038/s41430-020-00702-7  
40.   Miyazawa Itsuko, Miura Katsuyuki, Miyagawa Naoko, et al. Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80. European Journal of Clinical Nutrition. 2020; 74 (1): 67-76. doi:10.1038/s41430-019-0424-y  
41.   Ishida Noriko, Aoki Yuichi, Katsuoka Fumiki, et al. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. Free Radical Biology and Medicine. 2020; 161 : 71-83. doi:10.1016/j.freeradbiomed.2020.09.023  
42.   Sakurai Nozomu, Mardani-Korrani Hossein, Nakayasu Masaru, et al. Metabolome Analysis Identified Okaramines in the Soybean Rhizosphere as a Legacy of Hairy Vetch. Frontiers in Genetics. 2020; 11 : . doi:10.3389/fgene.2020.00114  
43.   Gervais Olivier, Ueno Kazuko, Kawai Yosuke, et al. Genomic Heritabilities and Correlations of 17 Traits Related to Obesity and Associated Conditions in the Japanese Population. G3: Genes|Genomes|Genetics. 2020; 10 (7): 2221-2228. doi:10.1534/g3.120.401242  
44.   Masamune Atsushi, Kotani Hiroshi, Sörgel Franziska Lena, et al. Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis. Gastroenterology. 2020; 158 (6): 1626-1641.e8. doi:10.1053/j.gastro.2020.01.005  
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47.   Fukunaga Hisanori, Ogawa Tsubasa, Asano Tomohiro, Ito Atsuo. Radiation Exposure Dose Distribution of Workers Engaged in Decontamination and Related Work Following the Fukushima Nuclear Disaster. Health Physics. 2020; Publish Ah : . doi:10.1097/HP.0000000000001309  
48.   Yoshida Ken, Yokota Kazuha, Kutsuwada Yukinobu, et al. Genome‐Wide Association Study of Lean Nonalcoholic Fatty Liver Disease Suggests Human Leukocyte Antigen as a Novel Candidate Locus. Hepatology Communications. 2020; 4 (8): 1124-1135. doi:10.1002/hep4.1529  
49.   Ueno Kazuko, Aiba Yoshihiro, Hitomi Yuki, et al. Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis. Hepatology Communications. 2020; 4 (5): 724-738. doi:10.1002/hep4.1497  
50.   Sugino Shigekazu, Konno Daisuke, Kawai Yosuke, et al. Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study. Human Genomics. 2020; 14 (1): 31. doi:10.1186/s40246-020-00282-4  
51.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2020; 16 (2): 295-300. doi:10.1080/21645515.2019.1655833  
52.   Iwama Noriyuki, Oba Mari S., Satoh Michihiro, et al. Association of maternal home blood pressure trajectory during pregnancy with infant birth weight: the BOSHI study. Hypertension Research. 2020; 43 (6): 550-559. doi:10.1038/s41440-020-0416-2  
53.   Wagata Maiko, Kogure Mana, Nakaya Naoki, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertension Research. 2020; 43 (11): 1277-1283. doi:10.1038/s41440-020-0463-8  
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56.   Shima Azusa, Miyamatsu Naomi, Miura Katsuyuki, et al. Relationship of household salt intake level with long-term all-cause and cardiovascular disease mortality in Japan: NIPPON DATA80. Hypertension Research. 2020; 43 (2): 132-139. doi:10.1038/s41440-019-0349-9  
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58.   Usuzaki Takuma, Chiba Shuji, Shimoyama Minoru, et al. A disparity in the number of studies related to COVID-19 and SARS-CoV-2 between low- and middle-income countries and high-income countries. International Health. 2020; : . doi:10.1093/inthealth/ihaa088  
59.   Tsuchiya Masami, Obara Taku, Miyazaki Makoto, et al. The quality assessment of the Japanese Adverse Drug Event Report database using vigiGrade. International Journal of Clinical Pharmacy. 2020; 42 (2): 728-736. doi:10.1007/s11096-020-00969-7  
60.   Kobayashi Natsuko, Nemoto Harumi, Seto Moe, et al. Experiences of perinatal women and public healthcare providers in a community affected by the great east Japan earthquake and tsunami: Concerns that must be considered for the mental healthcare of perinatal women in postdisaster settings. International Journal of Disaster Risk Reduction. 2020; 51 : 101767. doi:10.1016/j.ijdrr.2020.101767  
61.   Katayanagi Mitsuaki, Seto Moe, Nakaya Naoki, et al. Impact of the Great East Japan Earthquake on the Employment Status and Mental Health Conditions of Affected Coastal Communities. International Journal of Environmental Research and Public Health. 2020; 17 (21): 8130. doi:10.3390/ijerph17218130  
62.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169  
63.   Fukunaga Hisanori. The Effect of Low Temperatures on Environmental Radiation Damage in Living Systems: Does Hypothermia Show Promise for Space Travel?. International Journal of Molecular Sciences. 2020; 21 (17): 6349. doi:10.3390/ijms21176349  
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65.   Oshitani Hitoshi. Cluster-Based Approach to Coronavirus Disease 2019 (COVID-19) Response in Japan, from February to April 2020. Japanese Journal of Infectious Diseases. 2020; 73 (6): 491-493. doi:10.7883/yoken.JJID.2020.363  
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67.   Kemmyo Sugiyama, Toru Tsuboya, Taketoshi Okita, Naho Tsuchiya, Kunio Tarasawa, Tomoaki Ogata, Shintaro Yanaka Akio Tomoda. Residents in a Remote Island Having Family Members in Distant Areas Showed Higher Preference for Place of End-of-Life Care: The Ajishima Study. JMA Journal. 2020; : 138-145. doi:10.31662/jmaj.2019-0026  
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69.   Hozawa Atsushi. Screening for Aortic Aneurysm: Further Evidence is Required to Clarify the Issue. Journal of Atherosclerosis and Thrombosis. 2020; : . doi:10.5551/jat.ED143  
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72.   Hishinuma Eiji, Gutiérrez Rico Evelyn, Hiratsuka Masahiro. In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase. Journal of Clinical Medicine. 2020; 9 (8): 2342. doi:10.3390/jcm9082342  
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75.   Itabashi Fumi, Hirata Takumi, Kogure Mana, et al. Combined associations of liver enzymes and obesity with diabetes mellitus prevalence: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200384  
76.   Yang Yunqing, Hozawa Atsushi, Kogure Mana, et al. Dietary Inflammatory Index Positively Associated With High-Sensitivity C-Reactive Protein Level in Japanese From NIPPON DATA2010. Journal of Epidemiology. 2020; 30 (2): 98-107. doi:10.2188/jea.JE20180156  
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78.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200338  
79.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Social predictors of continued and indoor smoking among partners of non-smoking pregnant women: the TMM BirThree Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200313  
80.   Kakuta Yoichi, Izumiyama Yasuhiro, Okamoto Daisuke, et al. High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype. Journal of Gastroenterology. 2020; 55 (1): 67-77. doi:10.1007/s00535-019-01638-x  
81.   Aizawa Yayoi, Nagami Fuji, Ohashi Noriko, Kato Kazuto. A proposal on the first Japanese practical guidance for the return of individual genomic results in research settings. Journal of Human Genetics. 2020; 65 (3): 251-261. doi:10.1038/s10038-019-0697-y  
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89.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Association of iron levels in hair with brain structures and functions in young adults. Journal of Trace Elements in Medicine and Biology. 2020; 58 : 126436. doi:10.1016/j.jtemb.2019.126436  
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97.   Baird Liam, Yamamoto Masayuki. NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer. Molecular and Cellular Biology. 2020; 41 (2): . doi:10.1128/MCB.00473-20  
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