Tohoku University Tohoku Medical Megabank Organization (2018)
2019.06.20

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7.   Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0  
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10.   Hirata Takumi, Okamura Tomonori. Association Between Glycemic Control and Incident Stroke ― Overview From an Epidemiologic Study ―. Circulation Journal. 2018; 82 (6): 1499-1500. doi:10.1253/circj.CJ-18-0422  
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14.   Saito Takahiro, Gutiérrez Rico Evelyn Marie, Kikuchi Aoi, et al. Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation. Drug Metabolism and Pharmacokinetics. 2018; 33 (6): 250-257. doi:10.1016/j.dmpk.2018.08.004  
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19.   Shiga Yukihiro, Akiyama Masato, Nishiguchi Koji M, et al. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Human Molecular Genetics. 2018; 27 (8): 1486-1496. doi:10.1093/hmg/ddy053  
20.   Kubota Yoshimi, Higashiyama Aya, Sugiyama Daisuke, et al. Association between impairment of salty taste recognition and masked hypertension based on home blood pressure in Japanese residents: the KOBE study. Hypertension Research. 2018; 41 (9): 756-762. doi:10.1038/s41440-018-0074-9  
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22.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Smoking among adults with serious psychological distress: Analysis of anonymized data from a national cross-sectional survey in Japan. Journal of Affective Disorders. 2018; 239 : 131-137. doi:10.1016/J.JAD.2018.07.008  
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27.   Kakuta Yoichi, Kawai Yosuke, Okamoto Daisuke, et al. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Journal of Gastroenterology. 2018; 53 (9): 1065-1078. doi:10.1007/s00535-018-1486-7  
28.   Naito Takeo, Yokoyama Naonobu, Kakuta Yoichi, et al. Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology. 2018; 33 (11): 1873-1881. doi:10.1111/jgh.14149  
29.   Yamamoto Kayono, Shimizu Atsushi, Aizawa Fumie, et al. A comparison of genome cohort participants’ genetic knowledge and preferences to receive genetic results before and after a genetics workshop. Journal of Human Genetics. 2018; 63 (11): 1139-1147. doi:10.1038/s10038-018-0494-z  
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31.   Shido K., Kojima K., Yamasaki K., et al. 299 A genome-wide association study identifies a novel susceptibility locus for total IgE in a Japanese population from Tohoku Medical Megabank cohort study. Journal of Investigative Dermatology. 2018; 138 (5): S51. doi:10.1016/j.jid.2018.03.305  
32.   Tanaka Yukari, Kanazawa Motoyori, Palsson Olafur S, et al. Increased Postprandial Colonic Motility and Autonomic Nervous System Activity in Patients With Irritable Bowel Syndrome: A Prospective Study. Journal of Neurogastroenterology and Motility. 2018; 24 (1): 87-95. doi:10.5056/jnm16216  
33.   Ohseto Hisashi, Ishikuro Mami, Kikuya Masahiro, et al. Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study. Journal of psychosomatic research. 2018; 107 : 20-25. doi:10.1016/j.jpsychores.2018.01.013  
34.   Jia Xiaoyuan, Horinouchi Tomoko, Hitomi Yuki, et al. Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population. Journal of the American Society of Nephrology. 2018; 29 (8): 2189-2199. doi:10.1681/ASN.2017080859  
35.   Zhang Xuewei, Kitatani Kazuyuki, Toyoshima Masafumi, et al. Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer. Molecular Cancer Therapeutics. 2018; 17 (1): 50-59. doi:10.1158/1535-7163.MCT-17-0173  
36.   Takeuchi Fumihiko, Akiyama Masato, Matoba Nana, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications. 2018; 9 (1): 5052. doi:10.1038/s41467-018-07345-0  
37.   Tadaka Shu, Saigusa Daisuke, Motoike Ikuko N., et al. jMorp: Japanese Multi Omics Reference Panel. Nucleic Acids Research. 2018; 46 (D1): D551-D557. doi:10.1093/nar/gkx978  
38.   Hasegawa-Minato Junko, Toyoshima Masafumi, Ishibashi Masumi, et al. Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers. Oncotarget. 2018; 9 (3): 3483-3496. doi:10.18632/oncotarget.23322  
39.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Antihypertensives prescribed for pregnant women in Japan: Prevalence and timing determined from a database of health insurance claims. Pharmacoepidemiology and Drug Safety. 2018; 27 (12): 1325-1334. doi:10.1002/pds.4654  
40.   Obayashi Takeshi, Aoki Yuichi, Tadaka Shu, et al. ATTED-II in 2018: A Plant Coexpression Database Based on Investigation of the Statistical Property of the Mutual Rank Index. Plant & cell physiology. 2018; 59 (1): e3. doi:10.1093/pcp/pcx191  
41.   Chiba Hirofumi, Kakuta Yoichi, Kinouchi Yoshitaka, et al. Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease. PLOS ONE. 2018; 13 (3): e0194036. doi:10.1371/journal.pone.0194036  
42.   Yodsurang Varalee, Tang Yaqi, Takahashi Yukie, et al. Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1. PLOS ONE. 2018; 13 (12): e0209096. doi:10.1371/journal.pone.0209096  
43.   Sugawara Junichi, Iwama Noriyuki, Hoshiai Tetsuro, et al. Regional Birth Outcomes after the 2011 Great East Japan Earthquake and Tsunami in Miyagi Prefecture. Prehospital and Disaster Medicine. 2018; 33 (02): 215-219. doi:10.1017/S1049023X18000183  
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45.   Kuroha Takeshi, Nagai Keisuke, Gamuyao Rico, et al. Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding. Science. 2018; 361 (6398): 181-186. doi:10.1126/science.aat1577  
46.   Hiyama Gen, Mizushima Shusei, Matsuzaki Mei, et al. Female Japanese quail visually differentiate testosterone-dependent male attractiveness for mating preferences. Scientific Reports. 2018; 8 (1): 10012. doi:10.1038/s41598-018-28368-z  
47.   Hachiya Tsuyoshi, Narita Akira, Ohmomo Hideki, et al. Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus. Scientific Reports. 2018; 8 (1): 14162. doi:10.1038/s41598-018-32074-1  
48.   Sato Kota, Saigusa Daisuke, Saito Ritsumi, et al. Metabolomic changes in the mouse retina after optic nerve injury. Scientific Reports. 2018; 8 (1): 11930. doi:10.1038/s41598-018-30464-z  
49.   Obara Taku, Ishikuro Mami, Tamiya Gen, et al. Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports. 2018; 8 (1): 14840. doi:10.1038/s41598-018-33110-w  
50.   Ishibashi Masumi, Toyoshima Masafumi, Zhang Xuewei, et al. Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer. Scientific Reports. 2018; 8 (1): 13207. doi:10.1038/s41598-018-31069-2  
51.   Sato Yukihiro, Aida Jun, Tsuboya Toru, et al. Generalized and particularized trust for health between urban and rural residents in Japan: A cohort study from the JAGES project. Social Science & Medicine. 2018; 202 : 43-53. doi:10.1016/j.socscimed.2018.02.015  
52.   Ito Hirotaka, Gotoda Takuji, Oyama Tsuneo, et al. Long-term oncological outcomes of submucosal manipulation during non-curative endoscopic submucosal dissection for submucosal invasive gastric cancer: a multicenter retrospective study in Japan. Surgical endoscopy. 2018; 32 (1): 196-203. doi:10.1007/s00464-017-5659-x  
53.   Kondo Hiroko X., Yoshida Norio, Shirota Matsuyuki, Kinoshita Kengo. Molecular Mechanism of Depolarization-Dependent Inactivation in W366F Mutant of Kv1.2. The Journal of Physical Chemistry B. 2018; 122 (48): 10825-10833. doi:10.1021/acs.jpcb.8b09446  
54.   Iwaki Masayo, Takeshita Kohei, Kondo Hiroko X., et al. Zn 2+ -Binding to the Voltage-Gated Proton Channel Hv1/VSOP. The Journal of Physical Chemistry B. 2018; 122 (39): 9076-9080. doi:10.1021/acs.jpcb.8b04890  
55.   Inagaki Masatoshi, Fujiwara Masaki, Nakaya Naoki, et al. Low Cancer Screening Rates among Japanese People with Schizophrenia: A Cross-Sectional Study. The Tohoku Journal of Experimental Medicine. 2018; 244 (3): 209-218. doi:10.1620/tjem.244.209  
56.   Ishikuro Mami, Obara Taku, Osanai Tamae, et al. Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2018; 246 (2): 97-105. doi:10.1620/tjem.246.97  
57.   Takahashi Nobuyuki, Li Feng, Fushima Tomofumi, et al. Vitamin B3 Nicotinamide: A Promising Candidate for Treating Preeclampsia and Improving Fetal Growth. The Tohoku journal of experimental medicine. 2018; 244 (3): 243-248. doi:10.1620/tjem.244.243  
58.   Kumada Kazuki, Yasuda Jun. Evolutionary acquired robustness and vulnerability in cancer genome: negligible negative selection in carcinogenesis. Translational Cancer Research. 2018; 7 (S4): S445-S448. doi:10.21037/tcr.2018.02.15  
59.   成田 暁, 中谷 直樹, 中村 智洋, et al. 東日本大震災における軽度身体的外傷と心理的苦痛の関連:七ヶ浜健康増進プロジェクト. 日本公衆衛生雑誌. 2018; 65 (4): 157-163. https://www.jstage.jst.go.jp/article/jph/65/4/65_17-075/_article/-char/ja/