Tohoku University Tohoku Medical Megabank Organization (2018)

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10.   Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0  
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18.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Association between serious psychological distress and nonparticipation in cancer screening and the modifying effect of socioeconomic status: Analysis of anonymized data from a national cross-sectional survey in Japan. Cancer. 2018; 124 (3): 555-562. doi:10.1002/cncr.31086  
19.   Tanikawa Chizu, Kamatani Yoichiro, Toyoshima Osamu, et al. Genome‐wide association study identifies gastric cancer susceptibility loci at 12q24.11‐12 and 20q11.21. Cancer Science. 2018; 109 (12): 4015-4024. doi:10.1111/cas.13815  
20.   Tanikawa Chizu, Kamatani Yoichiro, Takahashi Atsushi, et al. GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. Carcinogenesis. 2018; 39 (5): 652-660. doi:10.1093/carcin/bgy026  
21.   Kikuchi Haruhisa, Kawai Kosuke, Nakashiro Yota, et al. Construction of a Meroterpenoid‐Like Compounds Library Based on Diversity‐Enhanced Extracts. Chemistry – A European Journal. 2018; 25 (4): chem.201805417. doi:10.1002/chem.201805417  
22.   Hirata Takumi, Okamura Tomonori. Association Between Glycemic Control and Incident Stroke ― Overview From an Epidemiologic Study ―. Circulation Journal. 2018; 82 (6): 1499-1500. doi:10.1253/circj.CJ-18-0422  
23.   Satoh Michihiro, Murakami Takahisa, Asayama Kei, et al. N-Terminal Pro-B-Type Natriuretic Peptide Is Not a Significant Predictor of Stroke Incidence After 5 Years ― The Ohasama Study ―. Circulation Journal. 2018; 82 (8): 2055-2062. doi:10.1253/circj.CJ-17-1227  
24.   Okami Yukiko, Ueshima Hirotsugu, Nakamura Yasuyuki, et al. Time-Related Changes in Relationships Between the Keys Score, Dietary Lipids, and Serum Total Cholesterol in Japan ― NIPPON DATA80/90/2010 ―. Circulation Journal. 2018; 83 (1): 147-155. doi:10.1253/circj.CJ-18-0628  
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26.   Ogata Soshiro, Kamide Kei, Asayama Kei, et al. Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study. Clinical and Experimental Hypertension. 2018; 40 (4): 363-369. doi:10.1080/10641963.2017.1384481  
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28.   Kubota Wataru, Honda Masataka, Okada Hirokazu, et al. A consensus statement on health-care transition of patients with childhood-onset chronic kidney diseases: providing adequate medical care in adolescence and young adulthood. Clinical and Experimental Nephrology. 2018; 22 (4): 743-751. doi:10.1007/s10157-018-1589-8  
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31.   Hishinuma Eiji, Narita Yoko, Saito Sakae, et al. Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals. Drug Metabolism and Disposition. 2018; 46 (8): 1083-1090. doi:10.1124/dmd.118.081737  
32.   Tachikawa Masanori, Sumiyoshiya Yuna, Saigusa Daisuke, et al. Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus. Drug Metabolism and Disposition. 2018; 46 (5): 610-618. doi:10.1124/dmd.117.079244  
33.   Kumondai Masaki, Ito Akio, Hishinuma Eiji, et al. Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS). Drug Metabolism and Pharmacokinetics. 2018; 33 (6): 258-263. doi:10.1016/j.dmpk.2018.08.003  
34.   Saito Takahiro, Gutiérrez Rico Evelyn Marie, Kikuchi Aoi, et al. Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation. Drug Metabolism and Pharmacokinetics. 2018; 33 (6): 250-257. doi:10.1016/j.dmpk.2018.08.004  
35.   Kumondai Masaki, Hosono Hiroki, Maekawa Masamitsu, et al. Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation. Drug Metabolism and Pharmacokinetics. 2018; 33 (1): 82-89. doi:10.1016/j.dmpk.2017.11.004  
36.   Okamoto Hiroshi, Taniyama Yusuke, Sakurai Tadashi, et al. Definitive chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-R) for advanced cervical esophageal cancer. Esophagus. 2018; 15 (4): 281-285. doi:10.1007/s10388-018-0627-7  
37.   Kogetsu Atsushi, Ogishima Soichi, Kato Kazuto. Authentication of Patients and Participants in Health Information Exchange and Consent for Medical Research: A Key Step for Privacy Protection, Respect for Autonomy, and Trustworthiness. Frontiers in Genetics. 2018; 9 : 167. doi:10.3389/fgene.2018.00167  
38.   Ogishima Soichi. [Human Genome Data and Drug Development]. Gan to kagaku ryoho. Cancer & chemotherapy. 2018; 45 (4): 597-600.  
39.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. Is the eCura system useful for selecting patients who require radical surgery after noncurative endoscopic submucosal dissection for early gastric cancer? A comparative study. Gastric Cancer. 2018; 21 (3): 481-489. doi:10.1007/s10120-017-0769-7  
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41.   Shibuya Yusuke, Tokunaga Hideki, Saito Sakae, et al. Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing. Genes, Chromosomes and Cancer. 2018; 57 (2): 51-60. doi:10.1002/gcc.22507  
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45.   Kubota Yoshimi, Higashiyama Aya, Sugiyama Daisuke, et al. Association between impairment of salty taste recognition and masked hypertension based on home blood pressure in Japanese residents: the KOBE study. Hypertension Research. 2018; 41 (9): 756-762. doi:10.1038/s41440-018-0074-9  
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47.   Nochioka Kotaro. Urinary sodium excretion in acute heart failure: Interaction between heart and kidney. International Journal of Cardiology. 2018; 254 : 244-245. doi:10.1016/j.ijcard.2017.11.098  
48.   Nakaya Naoki, Nemoto Harumi, Yi Carine, et al. Effect of tsunami drill experience on evacuation behavior after the onset of the Great East Japan Earthquake. International Journal of Disaster Risk Reduction. 2018; 28 : 206-213. doi:10.1016/j.ijdrr.2018.02.037  
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51.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Smoking among adults with serious psychological distress: Analysis of anonymized data from a national cross-sectional survey in Japan. Journal of Affective Disorders. 2018; 239 : 131-137. doi:10.1016/j.jad.2018.07.008  
52.   Kanaya Akihiro, Sato Toshihiro, Fuse Nobuo, et al. Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics. Journal of Anesthesia. 2018; 32 (2): 236-243. doi:10.1007/s00540-018-2470-3  
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59.   Kakuta Yoichi, Kawai Yosuke, Okamoto Daisuke, et al. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Journal of Gastroenterology. 2018; 53 (9): 1065-1078. doi:10.1007/s00535-018-1486-7  
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66.   Kondo Hiroko X, Yoshida Norio, Shirota Matsuyuki, Kinoshita Kengo. Molecular Mechanism of Depolarization-Dependent Inactivation in W366F Mutant of Kv1.2. Journal of Physical Chemistry B. 2018; 122 (48): 10825-10833. doi:10.1021/acs.jpcb.8b09446  
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