Tohoku University Tohoku Medical Megabank Organization (2017)
2019.09.18

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2.   Nezu Masahiro, Suzuki Norio, Yamamoto Masayuki. Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression. American Journal of Nephrology. 2017; 45 (6): 473-483. doi:10.1159/000475890  
3.   Mishima Eikan, Fukuda Shinji, Kanemitsu Yoshitomi, et al. Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model. American Journal of Physiology-Renal Physiology. 2017; 315 (4): F824-F833. doi:10.1152/ajprenal.00314.2017  
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7.   Takayanagi Yuki, Yoshida Masahide, Takashima Akihide, et al. Activation of Supraoptic Oxytocin Neurons by Secretin Facilitates Social Recognition. Biological Psychiatry. 2017; 81 (3): 243-251. doi:10.1016/j.biopsych.2015.11.021  
8.   Katayama Saori, Suzuki Mikiko, Yamaoka Ayaka, et al. GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. Blood. 2017; 130 (7): 908-919. doi:10.1182/blood-2016-12-756767  
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13.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Lenticular nucleus correlates of general self-efficacy in young adults. Brain Structure and Function. 2017; 222 (7): 3309-3318. doi:10.1007/s00429-017-1406-2  
14.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Mean diffusivity of basal ganglia and thalamus specifically associated with motivational states among mood states. Brain Structure and Function. 2017; 222 (2): 1027-1037. doi:10.1007/s00429-016-1262-5  
15.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. The anterior midcingulate cortex as a neural node underlying hostility in young adults. Brain Structure and Function. 2017; 222 (1): 61-70. doi:10.1007/s00429-016-1200-6  
16.   Yu Zhiqian, Fukushima Hotaka, Ono Chiaki, et al. Microglial production of TNF-alpha is a key element of sustained fear memory. Brain, Behavior, and Immunity. 2017; 59 : 313-321. doi:10.1016/j.bbi.2016.08.011  
17.   Pan Xiaoqing, Nariai Naoki, Fukuhara Noriko, et al. Monitoring of minimal residual disease in early T-cell precursor acute lymphoblastic leukaemia by next-generation sequencing. British Journal of Haematology. 2017; 176 (2): 318-321. doi:10.1111/bjh.13948  
18.   Nagai Masato, Murakami Yoshitaka, Tamakoshi Akiko, et al. Fasting but not casual blood glucose is associated with pancreatic cancer mortality in Japanese: EPOCH-JAPAN. Cancer Causes & Control. 2017; 28 (6): 625-633. doi:10.1007/s10552-017-0884-0  
19.   Bowman John L., Kohchi Takayuki, Yamato Katsuyuki T., et al. Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome. Cell. 2017; 171 (2): 287-304.e15. doi:10.1016/j.cell.2017.09.030  
20.   Yagishita Yoko, Uruno Akira, Fukutomi Toshiaki, et al. Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress. Cell reports. 2017; 18 (8): 2030-2044. doi:10.1016/j.celrep.2017.01.064  
21.   Tsugita Misato, Morimoto Nobuyuki, Tashiro Manabu, et al. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Reports. 2017; 18 (5): 1298-1311. doi:10.1016/j.celrep.2017.01.004  
22.   Nakano Tadashi, Mizoue Shiro, Fuse Nobuo, et al. Fixed combination of travoprost and timolol maleate reduces intraocular pressure in Japanese patients with primary open-angle glaucoma or ocular hypertension: analysis by prostaglandin analogue. Clinical ophthalmology (Auckland, N.Z.). 2017; 11 : 55-61. doi:10.2147/OPTH.S120639  
23.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Selective serotonin reuptake inhibitors and risk of major congenital anomalies for pregnancies in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study. Congenital Anomalies. 2017; 57 (3): 72-78. doi:10.1111/cga.12202  
24.   Hatta Waku, Koike Tomoyuki, Iijima Katsunori, et al. The Risk Factors for Metastasis in Non-Ampullary Duodenal Neuroendocrine Tumors Measuring 20 mm or Less in Diameter. Digestion. 2017; 95 (3): 201-209. doi:10.1159/000459619  
25.   Sakurai Kasumi, Nishigori Hidekazu, Nishigori Toshie, et al. Incidence of Domestic Violence Against Pregnant Females After the Great East Japan Earthquake in Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (02): 216-226. doi:10.1017/dmp.2016.109  
26.   Nishigori Hidekazu, Nishigori Toshie, Sakurai Kasumi, et al. Pregnant Women’s Awareness of Social Capital in the Great East Japan Earthquake-Affected Areas of Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (03): 355-364. doi:10.1017/dmp.2016.150  
27.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Psychological Distress and the Risk of Withdrawing From Hypertension Treatment After an Earthquake Disaster. Disaster Medicine and Public Health Preparedness. 2017; 11 (2): 179-182. doi:10.1017/dmp.2016.102  
28.   Matsuhashi Tetsuro, Sato Takeya, Kanno Shin-ichiro, et al. Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases. EBioMedicine. 2017; 20 : 27-38. doi:10.1016/j.ebiom.2017.05.016  
29.   Sakai Taichi, Sugawara Yumi, Watanabe Ikue, et al. Age at first birth and long-term mortality for mothers: the Ohsaki cohort study. Environmental Health and Preventive Medicine. 2017; 22 (1): 24. doi:10.1186/s12199-017-0631-x  
30.   Hidaka Hiroshi, Ozawa Daiki, Kuriyama Shinichi, et al. Risk factors for delayed oral dietary intake in patients with deep neck infections including descending necrotizing mediastinitis. European Archives of Oto-Rhino-Laryngology. 2017; 274 (11): 3951-3958. doi:10.1007/s00405-017-4716-3  
31.   Tsuchida Kouhei, Tsujita Tadayuki, Hayashi Makiko, et al. Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation. Free radical biology & medicine. 2017; 103 : 236-247. doi:10.1016/j.freeradbiomed.2016.12.041  
32.   Ikeda Shigeyuki, Takeuchi Hikaru, Taki Yasuyuki, et al. A Comprehensive Analysis of the Correlations between Resting-State Oscillations in Multiple-Frequency Bands and Big Five Traits. Frontiers in Human Neuroscience. 2017; 11 (14): 2146-2160. doi:10.3389/fnhum.2017.00321  
33.   Motomura Yuki, Kitamura Shingo, Nakazaki Kyoko, et al. Recovery from Unrecognized Sleep Loss Accumulated in Daily Life Improved Mood Regulation via Prefrontal Suppression of Amygdala Activity. Frontiers in Neurology. 2017; 8 : . doi:10.3389/fneur.2017.00306  
34.   Hasegawa Atsushi, Shimizu Ritsuko. GATA1 Activity Governed by Configurations of cis-Acting Elements. Frontiers in Oncology. 2017; 6 : . doi:10.3389/fonc.2016.00269  
35.   Matsuura Kentaro, Sawai Hiromi, Ikeo Kazuho, et al. Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. Gastroenterology. 2017; 152 (6): 1383-1394. doi:10.1053/j.gastro.2017.01.041  
36.   Kaneko Hiroshi, Katoh Takehide, Hirano Ikuo, et al. Induction of erythropoietin gene expression in epithelial cells by chemicals identified in GATA inhibitor screenings. Genes to cells : devoted to molecular & cellular mechanisms. 2017; 22 (11): 939-952. doi:10.1111/gtc.12537  
37.   Ueki Masao, Kawasaki Yoshinori, Tamiya Gen. Detecting genetic association through shortest paths in a bidirected graph. Genetic Epidemiology. 2017; 41 (6): 481-497. doi:10.1002/gepi.22051  
38.   Tomata Yasutake, Sugiyama Kemmyo, Kaiho Yu, et al. Predictive ability of a simple subjective memory complaints scale for incident dementia: Evaluation of Japan's national checklist, the “Kihon Checklist”. Geriatrics & Gerontology International. 2017; 17 (9): 1300-1305. doi:10.1111/ggi.12864  
39.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Creative females have larger white matter structures: Evidence from a large sample study. Human brain mapping. 2017; 38 (1): 414-430. doi:10.1002/hbm.23369  
40.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. The VEGF gene polymorphism impacts brain volume and arterial blood volume. Human Brain Mapping. 2017; 38 (7): 3516-3526. doi:10.1002/hbm.23606  
41.   Kawashima Minae, Hitomi Yuki, Aiba Yoshihiro, et al. Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population. Human Molecular Genetics. 2017; 26 (3): ddw406. doi:10.1093/hmg/ddw406  
42.   Metoki Hirohito, Iwama Noriyuki, Ishikuro Mami, et al. Monitoring and evaluation of out-of-office blood pressure during pregnancy. Hypertension research : official journal of the Japanese Society of Hypertension. 2017; 40 (2): 107-109. doi:10.1038/hr.2016.112  
43.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Seasonal variation in self-measured home blood pressure among patients on antihypertensive medications: HOMED-BP study. Hypertension research : official journal of the Japanese Society of Hypertension. 2017; 40 (3): 284-290. doi:10.1038/hr.2016.133  
44.   Kato N, Isojima T, Yokoya S, et al. Earlier BMI rebound and lower pre-rebound BMI as risk of obesity among Japanese preschool children. International Journal of Obesity. 2017; 42 (1): 52-58. doi:10.1038/ijo.2017.242  
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46.   Hamanaka Teruhiko, Kimura Masae, Sakurai Tetsuro, et al. A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients. Investigative Opthalmology & Visual Science. 2017; 58 (5): 2818. doi:10.1167/iovs.16-20646  
47.   Oba Akira, Nakaya Naoki, Saito-Nakaya Kumi, et al. Psychological distress in men with prostate cancer and their partners before and after cancer diagnosis: a longitudinal study. Japanese Journal of Clinical Oncology. 2017; 47 (8): 735-742. doi:10.1093/jjco/hyx066  
48.   Hotta Kinichi, Matsuda Takahisa, Kakugawa Yasuo, et al. Regional colorectal cancer screening program using colonoscopy on an island: a prospective Nii-jima study. Japanese Journal of Clinical Oncology. 2017; 47 (2): 118-122. doi:10.1093/jjco/hyw155  
49.   Liu Ta-Chiang, Naito Takeo, Liu Zhenqiu, et al. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients. JCI insight. 2017; 2 (6): e91917. doi:10.1172/jci.insight.91917  
50.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Risk Factors for Stroke among Young-Old and Old-Old Community-Dwelling Adults in Japan: The Ohasama Study. Journal of Atherosclerosis and Thrombosis. 2017; 24 (3): 290-300. doi:10.5551/jat.35766  
51.   Kanemitsu Yoshitomi, Asaji Kei, Matsumoto Yotaro, et al. Simultaneous quantitative analysis of uremic toxins by LC–MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column. Journal of Chromatography B. 2017; 1068-1069 : 1-8. doi:10.1016/j.jchromb.2017.10.009  
52.   Kumagai Chihiro, Sato Yukuto, Yamashita Riu, et al. Semi-automated quantitative analysis of the human skin microbiome diversity. Journal of Dermatological Science. 2017; 86 (2): e75. doi:10.1016/j.jdermsci.2017.02.219  
53.   Kikuya Masahiro, Matsubara Hiroko, Ishikuro Mami, et al. Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey. Journal of Epidemiology. 2017; 27 (10): 462-468. doi:10.1016/j.je.2016.09.012  
54.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the health examination survey on early childhood physical growth in the Great East Japan Earthquake affected areas. Journal of Epidemiology. 2017; 27 (3): 135-142. doi:10.1016/j.je.2016.03.001  
55.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. Is radical surgery necessary in all patients who do not meet the curative criteria for endoscopic submucosal dissection in early gastric cancer? A multi-center retrospective study in Japan. Journal of Gastroenterology. 2017; 52 (2): 175-184. doi:10.1007/s00535-016-1210-4  
56.   Ueta Mayumi, Sawai Hiromi, Shingaki Ryosei, et al. Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens–Johnson syndrome with severe ocular complications. Journal of Human Genetics. 2017; 62 (4): 485-489. doi:10.1038/jhg.2016.160  
57.   Yamamoto Kayono, Hachiya Tsuyoshi, Fukushima Akimune, et al. Population-based biobank participants’ preferences for receiving genetic test results. Journal of Human Genetics. 2017; 62 (12): 1037-1048. doi:10.1038/jhg.2017.81  
58.   Asayama Kei, Hozawa Atsushi, Taguri Masataka, et al. Blood pressure, heart rate, and double product in a pooled cohort. Journal of Hypertension. 2017; 35 (9): 1808-1815. doi:10.1097/HJH.0000000000001399  
59.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Home blood pressure predicts stroke incidence among older adults with impaired physical function. Journal of Hypertension. 2017; 35 (12): 2395-2401. doi:10.1097/HJH.0000000000001473  
60.   Shido K., Kojima K., Hozawa A., et al. 503 Genome-wide association study identifies novel susceptibility loci for tanning ability in Japanese population. Journal of Investigative Dermatology. 2017; 137 (5): S86. doi:10.1016/j.jid.2017.02.523  
61.   Miyashita Masako, Ishikuro Mami, Kikuya Masahiro, et al. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. Journal of Pediatrics and Congenital Disorders. 2017; 4 : . http://www.jscholaronline.org/articles/JPCD/Development-of-a-Questionnaire.pdf  
62.   Tsubota-Utsugi Megumi, Satoh Michihiro, Tomita Naoki, et al. Lacunar Infarcts Rather than White Matter Hyperintensity as a Predictor of Future Higher Level Functional Decline: The Ohasama Study. Journal of Stroke and Cerebrovascular Diseases. 2017; 26 (2): 376-384. doi:10.1016/j.jstrokecerebrovasdis.2016.09.036  
63.   Yokoro Miyuki, Nakayama Yosuke, Yamagishi Sho-ichi, et al. Asymmetric Dimethylarginine Contributes to the Impaired Response to Erythropoietin in CKD-Anemia. Journal of the American Society of Nephrology. 2017; 28 (9): 2670-2680. doi:10.1681/ASN.2016111184  
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66.   Tatewaki Yasuko, Mutoh Tatsushi, Thyreau Benjamin, et al. Phase Difference-Enhanced Magnetic Resonance (MR) Imaging (PADRE) Technique for the Detection of Age-Related Microstructural Changes in Optic Radiation: Comparison with Diffusion Tensor Imaging (DTI). Medical Science Monitor. 2017; 23 : 5495-5503. doi:10.12659/MSM.905571  
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94.   Hachiya Tsuyoshi, Komaki Shohei, Hasegawa Yutaka, et al. Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c. Scientific Reports. 2017; 7 (1): 16147. doi:10.1038/s41598-017-16493-0  
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