Tohoku University Tohoku Medical Megabank Organization
2021.03.05

1.   Zempo Hirofumi, Kim Su-Jeong, Fuku Noriyuki, et al. A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c. Aging. 2021; : . doi:10.18632/aging.202529  
2.   Iwama Taiga, Kano Kuniyuki, Saigusa Daisuke, et al. Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag. Analytical Chemistry. 2021; : acs.analchem.0c04479. doi:10.1021/acs.analchem.0c04479  
3.   Kikuchi Daisuke, Obara Taku, Tokunaga Misaki, et al. Drug prescription for attention deficit hyperactivity disorder drugs in pediatric outpatients: A retrospective survey of Japanese administrative data (2012–2018). Asian Journal of Psychiatry. 2021; 57 : 102512. doi:10.1016/j.ajp.2020.102512  
4.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. General Intelligence Is Associated with Working Memory-Related Functional Connectivity Change: Evidence from a Large-Sample Study. Brain Connectivity. 2021; : brain.2020.0769. doi:10.1089/brain.2020.0769  
5.   Suzuki Shiori, Goto Atsushi, Nakatochi Masahiro, et al. Body mass index and colorectal cancer risk: A Mendelian randomization study. Cancer Science. 2021; : cas.14824. doi:10.1111/cas.14824  
6.   Chiba Yuki, Nagasawa Tasuku, Kin Saori, et al. Spontaneous remission of minimal change nephrotic syndrome in an elderly man. CEN Case Reports. 2021; : . doi:10.1007/s13730-020-00554-x  
7.   Takeuchi Hikaru, Tomita Hiroaki, Browne Ryan, et al. Sex-Dependent Effects of the APOE ɛ4 Allele on Behavioral Traits and White Matter Structures in Young Adults. Cerebral Cortex. 2021; 31 (1): 672-680. doi:10.1093/cercor/bhaa251  
8.   Kikuchi Saya, Kobayashi Natsuko, Watanabe Zen, et al. The delivery of a placenta/fetus with high gonadal steroid production contributes to postpartum depressive symptoms. Depression and Anxiety. 2021; : da.23134. doi:10.1002/da.23134  
9.   Saigusa Daisuke, Matsukawa Naomi, Hishinuma Eiji, Koshiba Seizo. Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics. Drug Metabolism and Pharmacokinetics. 2021; 37 : 100373. doi:10.1016/j.dmpk.2020.11.008  
10.   Miyauchi Kenichiro, Nakai Taku, Saito Sakae, et al. Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions. EBioMedicine. 2021; 64 : 103209. doi:10.1016/j.ebiom.2021.103209  
11.   Suzuki Hideaki, Yasuda Satoshi, Shimokawa Hiroaki. Brain–heart connection in Takotsubo syndrome before onset. European Heart Journal. 2021; : . doi:10.1093/eurheartj/ehab026  
12.   Kageyama Sakiko, Mori Naoko, Mugikura Shunji, et al. Gaussian mixture model-based cluster analysis of apparent diffusion coefficient values: a novel approach to evaluate uterine endometrioid carcinoma grade. European Radiology. 2021; 31 (1): 55-64. doi:10.1007/s00330-020-07047-6  
13.   YUMOTO Akane, KOKUBO Toshiaki, IZUMI Ryutaro, et al. Novel method for evaluating the health condition of mice in space through a video downlink. Experimental Animals. 2021; : . doi:10.1538/expanim.20-0102  
14.   Saito Sakae, Aoki Yuichi, Tamahara Toru, et al. Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project. Frontiers in Cellular and Infection Microbiology. 2021; 10 : . doi:10.3389/fcimb.2020.604596  
15.   Isaka Yuichi, Nishio Shin-ya, Hishinuma Eiji, et al. Improvement of a Rapid and Highly Sensitive Method for the Diagnosis of the Mitochondrial m.1555A>G Mutation Based on a Single-Stranded Tag Hybridization Chromatographic Printed-Array Strip. Genetic Testing and Molecular Biomarkers. 2021; 25 (1): 79-83. doi:10.1089/gtmb.2020.0105  
16.   Kobayashi Tomonori, Noda Aoi, Obara Taku, et al. Knowledge, Attitudes, and Practice of Hospital Pharmacists Regarding Pharmacovigilance and Adverse Drug Reaction Reporting in Japan. Hospital Pharmacy. 2021; 56 (1): 7-16. doi:10.1177/0018578719851455  
17.   Nagaoka Shinichi, Yamaguchi-Kabata Yumi, Shiga Naomi, et al. Estimation of the carrier frequencies and proportions of potential patients by detecting causative gene variants associated with autosomal recessive bone dysplasia using a whole-genome reference panel of Japanese individuals. Human Genome Variation. 2021; 8 (1): 2. doi:10.1038/s41439-020-00133-7  
18.   Kadowaki Sayaka, Kadowaki Takashi, Hozawa Atsushi, et al. Differences between home blood pressure and strictly measured office blood pressure and their determinants in Japanese men. Hypertension Research. 2021; 44 (1): 80-87. doi:10.1038/s41440-020-00533-w  
19.   Kogure Mana, Nakaya Naoki, Hirata Takumi, et al. Sodium/potassium ratio change was associated with blood pressure change: possibility of population approach for sodium/potassium ratio reduction in health checkup. Hypertension Research. 2021; 44 (2): 225-231. doi:10.1038/s41440-020-00536-7  
20.   Suzuki Kaoru, Kakuta Yoichi, Naito Takeo, et al. Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 2021; : . doi:10.1093/ibd/izab004  
21.   Hakamata Mariko, Hokari Satoshi, Ohshima Yasuyoshi, et al. Chronic Hypercapnic Respiratory Failure in an Adult Patient with Silver-Russell Syndrome: A Case Report. Internal Medicine. 2021; : . doi:10.2169/internalmedicine.5479-20  
22.   Saito Masahiro, Koike Tomoyuki, Abe Yasuaki, et al. The Development of Foveolar-type Gastric Adenocarcinoma during Maintenance Therapy of Vonoprazan for Reflux Esophagitis. Internal Medicine. 2021; 60 (3): 391-396. doi:10.2169/internalmedicine.5431-20  
23.   Murakami Keiko, Ueno Fumihiko, Nakamura Ibuki, et al. Maternal personality and postnatal bonding disorder in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2021; 282 : 580-586. doi:10.1016/j.jad.2020.12.187  
24.   Cvetko Filip, Caldwell Stuart T., Higgins Maureen, et al. Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. Journal of Biological Chemistry. 2021; 296 : 100169. doi:10.1074/jbc.RA120.016551  
25.   Kogure Mana, Tsuchiya Naho, Narita Akira, et al. Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90. Journal of Epidemiology. 2021; 31 (2): 119-124. doi:10.2188/jea.JE20190234  
26.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Epidemiology. 2021; 31 (1): 65-76. doi:10.2188/jea.JE20190271  
27.   Yajima Misako, Kakuta Risako, Saito Yutaro, et al. A global phylogenetic analysis of Japanese tonsil-derived Epstein–Barr virus strains using viral whole-genome cloning and long-read sequencing. Journal of General Virology. 2021; : . doi:10.1099/jgv.0.001549  
28.   Narita Akira, Ueki Masao, Tamiya Gen. Artificial intelligence powered statistical genetics in biobanks. Journal of Human Genetics. 2021; 66 (1): 61-65. doi:10.1038/s10038-020-0822-y  
29.   Fukunaga Koya, Hishinuma Eiji, Hiratsuka Masahiro, et al. Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population. Journal of Human Genetics. 2021; 66 (2): 139-149. doi:10.1038/s10038-020-0815-x  
30.   Kumondai Masaki, Ito Akio, Gutiérrez Rico Evelyn Marie, et al. Functional Assessment of 12 Rare Allelic CYP2C9 Variants Identified in a Population of 4773 Japanese Individuals. Journal of Personalized Medicine. 2021; 11 (2): 94. doi:10.3390/jpm11020094  
31.   Kogaki Takahiro, Ohshio Ikumi, Ura Hasumi, et al. Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 2021; 197 : 113943. doi:10.1016/j.jpba.2021.113943  
32.   Ito Yoshihiko, Hong Guang, Tsuboi Akito, et al. Multivariate analysis reveals oral health-related quality of life of complete denture wearers with denture adhesives: a multicenter randomized controlled trial. Journal of Prosthodontic Research. 2021; : . doi:10.2186/jpr.JPR_D_20_00132  
33.   Ikeda Atsushi, Nagayama Satoshi, Sumazaki Makoto, et al. Colorectal cancer-derived CAT1-positive extracellular vesicles alter nitric oxide metabolism in endothelial cells and promote angiogenesis. Molecular Cancer Research. 2021; : molcanres.MCR-20-0827-E.2020. doi:10.1158/1541-7786.MCR-20-0827  
34.   Hattori Shin-ichiro, Higashi-Kuwata Nobuyo, Hayashi Hironori, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature Communications. 2021; 12 (1): 668. doi:10.1038/s41467-021-20900-6  
35.   Takayama Jun, Tadaka Shu, Yano Kenji, et al. Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. Nature Communications. 2021; 12 (1): 226. doi:10.1038/s41467-020-20146-8  
36.   Gharahkhani Puya, Jorgenson Eric, Hysi Pirro, et al. Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications. 2021; 12 (1): 1258. doi:10.1038/s41467-020-20851-4  
37.   Tadros Rafik, Francis Catherine, Xu Xiao, et al. Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nature Genetics. 2021; 53 (2): 128-134. doi:10.1038/s41588-020-00762-2  
38.   Tadaka Shu, Hishinuma Eiji, Komaki Shohei, et al. jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population. Nucleic Acids Research. 2021; 49 (D1): D536-D544. doi:10.1093/nar/gkaa1034  
39.   Tokunaga Hideki, Iida Keita, Hozawa Atsushi, et al. Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2). PLOS ONE. 2021; 16 (1): e0236907. doi:10.1371/journal.pone.0236907  
40.   Kojima Kaname, Shido Kosuke, Tamiya Gen, et al. Facial UV photo imaging for skin pigmentation assessment using conditional generative adversarial networks. Scientific Reports. 2021; 11 (1): 1213. doi:10.1038/s41598-020-79995-4  
41.   Oe Yuji, Mitsui Shohei, Sato Emiko, et al. Lack of Endothelial Nitric Oxide Synthase Accelerates Ectopic Calcification in Uremic Mice Fed an Adenine and High Phosphorus Diet. The American Journal of Pathology. 2021; 191 (2): 283-293. doi:10.1016/j.ajpath.2020.10.012  
42.   Usuzaki Takuma, Ishikuro Mami, Obara Taku. Commentary on “Determinants of pre‐eclampsia among pregnant women attending perinatal care in hospitals of the Omo district, Southern Ethiopia”. The Journal of Clinical Hypertension. 2021; 23 (1): 163-165. doi:10.1111/jch.14110  
43.   Ogata Yohei, Hatta Waku, Koike Tomoyuki, et al. Predictors of Early and Late Mortality after Endoscopic Resection for Esophageal Squamous Cell Carcinoma. The Tohoku Journal of Experimental Medicine. 2021; 253 (1): 29-39. doi:10.1620/tjem.253.29  
44.   Shigemizu Daichi, Mitsumori Risa, Akiyama Shintaro, et al. Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer’s disease risk. Translational Psychiatry. 2021; 11 (1): 151. doi:10.1038/s41398-021-01272-3  
45.   Ishikawa Tomohiko, Ogawa Takenori, Nakanome Ayako, et al. Whole exome sequencing and establishment of an organoid culture of the carcinoma showing thymus-like differentiation (CASTLE) of the parotid gland. Virchows Archiv. 2021; : . doi:10.1007/s00428-020-02981-8  
46.   Oe Chihiro, Hayashi Hironori, Hirata Kazushige, et al. Pyrimidine Analogues as a New Class of Gram-Positive Antibiotics, Mainly Targeting Thymineless-Death Related Proteins. ACS Infectious Diseases. 2020; 6 (6): 1490-1500. doi:10.1021/acsinfecdis.9b00305  
47.   Akiyama Tomoyuki, Saigusa Daisuke, Hyodo Yuki, et al. Metabolic Profiling of the Cerebrospinal Fluid in Pediatric Epilepsy. Acta medica Okayama. 2020; 74 (1): 65-72. doi:10.18926/AMO/57955  
48.   Mitsui Shohei, Oe Yuji, Sekimoto Akiyo, et al. Dual blockade of protease-activated receptor 1 and 2 additively ameliorates diabetic kidney disease. American Journal of Physiology-Renal Physiology. 2020; 318 (5): F1067-F1073. doi:10.1152/ajprenal.00595.2019  
49.   Nakayama Akiyoshi, Nakatochi Masahiro, Kawamura Yusuke, et al. Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Annals of the Rheumatic Diseases. 2020; 79 (5): 657-665. doi:10.1136/annrheumdis-2019-216644  
50.   Saito Sho, Hayakawa Kayoko, Tsuzuki Shinya, et al. A Matched Case-Case-Control Study of the Impact of Clinical Outcomes and Risk Factors of Patients with IMP-Type Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae in Japan. Antimicrobial Agents and Chemotherapy. 2020; 65 (3): . doi:10.1128/AAC.01483-20  
51.   Nakagawara Kohsuke, Hayashi Hironori, Kawaji Kumi, et al. Application of human lymphoid cells for the evaluation of antivirals against human adenovirus type 19: Zalcitabine has superior activity compared to cidofovir. Antiviral Chemistry and Chemotherapy. 2020; 28 : 204020662092131. doi:10.1177/2040206620921319  
52.   Nakao Yuki, Sasaki AI, Obara Taku, et al. Knowledge of Cervical Cancer and Human Papillomavirus among Japanese Women. Asian Pacific Journal of Cancer Prevention. 2020; 21 (12): 3527-3532. doi:10.31557/APJCP.2020.21.12.3527  
53.   Yanagisawa Michiko, Namekata Kazuhiko, Aida Tomomi, et al. EAAT1 variants associated with glaucoma. Biochemical and Biophysical Research Communications. 2020; 529 (4): 943-949. doi:10.1016/j.bbrc.2020.06.099  
54.   Sato Emiko, Hosomi Koji, Sekimoto Akiyo, et al. Effects of the oral adsorbent AST-120 on fecal p-cresol and indole levels and on the gut microbiota composition. Biochemical and Biophysical Research Communications. 2020; 525 (3): 773-779. doi:10.1016/j.bbrc.2020.02.141  
55.   Sato Emiko, Tsunokuni Yukako, Kaneko Manami, et al. Metabolomics of a mouse model of preeclampsia induced by overexpressing soluble fms-like tyrosine kinase 1. Biochemical and Biophysical Research Communications. 2020; 527 (4): 1064-1071. doi:10.1016/j.bbrc.2020.04.079  
56.   Ishikawa Tomofumi, Obara Taku, Jin Kazutaka, et al. Folic acid prescribed to prenatal and postpartum women who are also prescribed antiepileptic drugs in Japan: Data from a health administrative database. Birth Defects Research. 2020; 112 (16): 1224-1233. doi:10.1002/bdr2.1748  
57.   Yamaoka Ayaka, Suzuki Mikiko, Katayama Saori, et al. EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis. Blood Advances. 2020; 4 (8): 1722-1736. doi:10.1182/bloodadvances.2019000978  
58.   Anzawa Hayato, Yamagata Hitoshi, Kinoshita Kengo. Theoretical characterisation of strand cross-correlation in ChIP-seq. BMC Bioinformatics. 2020; 21 (1): 417. doi:10.1186/s12859-020-03729-6  
59.   Wada Yoichi, Arai-Ichinoi Natsuko, Kikuchi Atsuo, et al. Hypoketotic hypoglycemia in citrin deficiency: a case report. BMC Pediatrics. 2020; 20 (1): 444. doi:10.1186/s12887-020-02349-6  
60.   Noda Aoi, Sakai Takamasa, Obara Taku, et al. Characteristics of pediatric adverse drug reaction reports in the Japanese Adverse Drug Event Report Database. BMC Pharmacology and Toxicology. 2020; 21 (1): 36. doi:10.1186/s40360-020-00412-7  
61.   Mizukami Miyako, Ishikawa Aki, Miyazaki Sachiko, et al. A de novo CHD3 variant in a child with intellectual disability, autism, joint laxity, and dysmorphisms. Brain and Development. 2020; : . doi:10.1016/j.braindev.2020.12.004  
62.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. Effect of the interaction between BDNF Val66Met polymorphism and daily physical activity on mean diffusivity. Brain Imaging and Behavior. 2020; 14 (3): 806-820. doi:10.1007/s11682-018-0025-8  
63.   Takeuchi Hikaru, Maruyama Tsukasa, Taki Yasuyuki, et al. Effects of training of shadowing and reading aloud of second language on working memory and neural systems. Brain Imaging and Behavior. 2020; : . doi:10.1007/s11682-020-00324-4  
64.   Ishii Hiroki, Saitoh Masao, Sakamoto Kaname, et al. Lipidome-based rapid diagnosis with machine learning for detection of TGF-β signalling activated area in head and neck cancer. British Journal of Cancer. 2020; 122 (7): 995-1004. doi:10.1038/s41416-020-0732-y  
65.   Hayashi Makiko, Kuga Ayumi, Suzuki Mikiko, et al. Microenvironmental Activation of Nrf2 Restricts the Progression of Nrf2-Activated Malignant Tumors. Cancer Research. 2020; 80 (16): 3331-3344. doi:10.1158/0008-5472.CAN-19-2888  
66.   Saigusa Daisuke, Motoike Ikuko N., Saito Sakae, et al. Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites. Cancer Science. 2020; 111 (2): 667-678. doi:10.1111/cas.14278  
67.   Yokose Takahiro, Kabe Yasuaki, Matsuda Atsushi, et al. O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer. Cancers. 2020; 12 (9): 2469. doi:10.3390/cancers12092469  
68.   Taguchi Keiko, Yamamoto Masayuki. The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment. Cancers. 2020; 13 (1): 46. doi:10.3390/cancers13010046  
69.   Afshinnekoo Ebrahim, Scott Ryan T., MacKay Matthew J., et al. Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration. Cell. 2020; 183 (5): 1162-1184. doi:10.1016/j.cell.2020.10.050  
70.   Matsunaga Hiroshi, Ito Kaoru, Akiyama Masato, et al. Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease. Circulation: Genomic and Precision Medicine. 2020; 13 (3): . doi:10.1161/CIRCGEN.119.002670  
71.   Noda Aoi, Obara Taku, Takada Kazuki, et al. Changes in community pharmacists’ knowledge, attitudes, and practice regarding the management of hypertension before and after educational interventions. Clinical and Experimental Hypertension. 2020; 42 (4): 322-327. doi:10.1080/10641963.2019.1652634  
72.   Noda Aoi, Obara Taku, Abe Shinya, et al. The present situation of home blood pressure measurement among outpatients in Japan. Clinical and Experimental Hypertension. 2020; 42 (1): 67-74. doi:10.1080/10641963.2019.1571601  
73.   Okuda Hiroshi, Okamoto Koji, Abe Michiaki, et al. Genome-wide association study identifies new loci for albuminuria in the Japanese population. Clinical and Experimental Nephrology. 2020; 24 (8): 1-9. doi:10.1007/s10157-020-01884-x  
74.   Nakamura Ryoichi, Misawa Kazuharu, Tohnai Genki, et al. A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis. Communications Biology. 2020; 3 (1): 526. doi:10.1038/s42003-020-01251-2  
75.   Shibayama Yuki, Takahashi Kazuo, Yamaguchi Hisateru, et al. Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H. Communications Biology. 2020; 3 (1): 724. doi:10.1038/s42003-020-01434-x  
76.   Koshiba Seizo, Motoike Ikuko N., Saigusa Daisuke, et al. Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population. Communications Biology. 2020; 3 (1): 662. doi:10.1038/s42003-020-01383-5  
77.   Suzuki Takafumi, Uruno Akira, Yumoto Akane, et al. Nrf2 contributes to the weight gain of mice during space travel. Communications Biology. 2020; 3 (1): 496. doi:10.1038/s42003-020-01227-2  
78.   Iwama Noriyuki, Sugiyama Takashi, Metoki Hirohito, et al. Associations between glycosylated hemoglobin level at less than 24 weeks of gestation and adverse pregnancy outcomes in Japan: The Japan Environment and Children’s Study (JECS). Diabetes Research and Clinical Practice. 2020; 169 : 108377. doi:10.1016/j.diabres.2020.108377  
79.   Norita Kazuaki, Asanuma Kiyotaka, Koike Tomoyuki, et al. Impaired Mucosal Integrity in Proximal Esophagus Is Involved in Development of Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease. Digestion. 2020; : 1-11. doi:10.1159/000508661  
80.   Gutiérrez Rico Evelyn Marie, Kikuchi Aoi, Saito Takahiro, et al. CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity. Drug Metabolism and Pharmacokinetics. 2020; 35 (1): 89-101. doi:10.1016/j.dmpk.2019.07.003  
81.   Furuse Yuki, Sando Eiichiro, Tsuchiya Naho, et al. Clusters of Coronavirus Disease in Communities, Japan, January–April 2020. Emerging Infectious Diseases. 2020; 26 (9): 2176-2179. doi:10.3201/eid2609.202272  
82.   Trivisano Marina, Ferretti Alessandro, Bebin Elizabeth, et al. Defining the phenotype of FHF1 developmental and epileptic encephalopathy. Epilepsia. 2020; 61 (7): . doi:10.1111/epi.16582  
83.   Suzuki Harumitsu, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern. European Journal of Clinical Nutrition. 2020; : . doi:10.1038/s41430-020-00823-z  
84.   Suzuki Taro, Nakamura Yasuyuki, Matsuo Keitaro, et al. A genome-wide association study on fish consumption in a Japanese population—the Japan Multi-Institutional Collaborative Cohort study. European Journal of Clinical Nutrition. 2020; : . doi:10.1038/s41430-020-00702-7  
85.   Miyazawa Itsuko, Miura Katsuyuki, Miyagawa Naoko, et al. Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80. European Journal of Clinical Nutrition. 2020; 74 (1): 67-76. doi:10.1038/s41430-019-0424-y  
86.   Ishida Noriko, Aoki Yuichi, Katsuoka Fumiki, et al. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. Free Radical Biology and Medicine. 2020; 161 : 71-83. doi:10.1016/j.freeradbiomed.2020.09.023  
87.   Sakurai Nozomu, Mardani-Korrani Hossein, Nakayasu Masaru, et al. Metabolome Analysis Identified Okaramines in the Soybean Rhizosphere as a Legacy of Hairy Vetch. Frontiers in Genetics. 2020; 11 : . doi:10.3389/fgene.2020.00114  
88.   Gervais Olivier, Ueno Kazuko, Kawai Yosuke, et al. Genomic Heritabilities and Correlations of 17 Traits Related to Obesity and Associated Conditions in the Japanese Population. G3: Genes|Genomes|Genetics. 2020; 10 (7): 2221-2228. doi:10.1534/g3.120.401242  
89.   Masamune Atsushi, Kotani Hiroshi, Sörgel Franziska Lena, et al. Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis. Gastroenterology. 2020; 158 (6): 1626-1641.e8. doi:10.1053/j.gastro.2020.01.005  
90.   Misawa Kazuharu, Hasegawa Takanori, Mishima Eikan, et al. Contribution of Rare Variants of the SLC22A12 Gene to the Missing Heritability of Serum Urate Levels. Genetics. 2020; 214 (4): 1079-1090. doi:10.1534/genetics.119.303006  
91.   Hatta Waku, Tsuji Yosuke, Yoshio Toshiyuki, et al. Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score. Gut. 2020; : gutjnl-2019-319926. doi:10.1136/gutjnl-2019-319926  
92.   Fukunaga Hisanori, Ogawa Tsubasa, Asano Tomohiro, Ito Atsuo. Radiation Exposure Dose Distribution of Workers Engaged in Decontamination and Related Work Following the Fukushima Nuclear Disaster. Health Physics. 2020; Publish Ah : . doi:10.1097/HP.0000000000001309  
93.   Yoshida Ken, Yokota Kazuha, Kutsuwada Yukinobu, et al. Genome‐Wide Association Study of Lean Nonalcoholic Fatty Liver Disease Suggests Human Leukocyte Antigen as a Novel Candidate Locus. Hepatology Communications. 2020; 4 (8): 1124-1135. doi:10.1002/hep4.1529  
94.   Ueno Kazuko, Aiba Yoshihiro, Hitomi Yuki, et al. Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis. Hepatology Communications. 2020; 4 (5): 724-738. doi:10.1002/hep4.1497  
95.   Sugino Shigekazu, Konno Daisuke, Kawai Yosuke, et al. Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study. Human Genomics. 2020; 14 (1): 31. doi:10.1186/s40246-020-00282-4  
96.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2020; 16 (2): 295-300. doi:10.1080/21645515.2019.1655833  
97.   Iwama Noriyuki, Oba Mari S., Satoh Michihiro, et al. Association of maternal home blood pressure trajectory during pregnancy with infant birth weight: the BOSHI study. Hypertension Research. 2020; 43 (6): 550-559. doi:10.1038/s41440-020-0416-2  
98.   Wagata Maiko, Kogure Mana, Nakaya Naoki, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertension Research. 2020; 43 (11): 1277-1283. doi:10.1038/s41440-020-0463-8  
99.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2  
100.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0  
101.   Shima Azusa, Miyamatsu Naomi, Miura Katsuyuki, et al. Relationship of household salt intake level with long-term all-cause and cardiovascular disease mortality in Japan: NIPPON DATA80. Hypertension Research. 2020; 43 (2): 132-139. doi:10.1038/s41440-019-0349-9  
102.   Okamoto Daisuke, Kawai Yosuke, Kakuta Yoichi, et al. Genetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array. Inflammatory Bowel Diseases. 2020; 26 (8): 1177-1187. doi:10.1093/ibd/izaa033  
103.   Usuzaki Takuma, Chiba Shuji, Shimoyama Minoru, et al. A disparity in the number of studies related to COVID-19 and SARS-CoV-2 between low- and middle-income countries and high-income countries. International Health. 2020; : . doi:10.1093/inthealth/ihaa088  
104.   Tsuchiya Masami, Obara Taku, Miyazaki Makoto, et al. The quality assessment of the Japanese Adverse Drug Event Report database using vigiGrade. International Journal of Clinical Pharmacy. 2020; 42 (2): 728-736. doi:10.1007/s11096-020-00969-7  
105.   Kobayashi Natsuko, Nemoto Harumi, Seto Moe, et al. Experiences of perinatal women and public healthcare providers in a community affected by the great east Japan earthquake and tsunami: Concerns that must be considered for the mental healthcare of perinatal women in postdisaster settings. International Journal of Disaster Risk Reduction. 2020; 51 : 101767. doi:10.1016/j.ijdrr.2020.101767  
106.   Katayanagi Mitsuaki, Seto Moe, Nakaya Naoki, et al. Impact of the Great East Japan Earthquake on the Employment Status and Mental Health Conditions of Affected Coastal Communities. International Journal of Environmental Research and Public Health. 2020; 17 (21): 8130. doi:10.3390/ijerph17218130  
107.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169  
108.   Fukunaga Hisanori. The Effect of Low Temperatures on Environmental Radiation Damage in Living Systems: Does Hypothermia Show Promise for Space Travel?. International Journal of Molecular Sciences. 2020; 21 (17): 6349. doi:10.3390/ijms21176349  
109.   Shimizu Ritsuko, Yamamoto Masayuki. Quantitative and qualitative impairments in GATA2 and myeloid neoplasms. IUBMB Life. 2020; 72 (1): 142-150. doi:10.1002/iub.2188  
110.   Oshitani Hitoshi. Cluster-Based Approach to Coronavirus Disease 2019 (COVID-19) Response in Japan, from February to April 2020. Japanese Journal of Infectious Diseases. 2020; 73 (6): 491-493. doi:10.7883/yoken.JJID.2020.363  
111.   Ohwada G, Minakuchi S, Sato Y, et al. Subjective Evaluation of Denture Adhesives: A Multicenter Randomized Controlled Trial. JDR Clinical & Translational Research. 2020; 5 (1): 50-61. doi:10.1177/2380084419837607  
112.   Kemmyo Sugiyama, Toru Tsuboya, Taketoshi Okita, Naho Tsuchiya, Kunio Tarasawa, Tomoaki Ogata, Shintaro Yanaka Akio Tomoda. Residents in a Remote Island Having Family Members in Distant Areas Showed Higher Preference for Place of End-of-Life Care: The Ajishima Study. JMA Journal. 2020; : 138-145. doi:10.31662/jmaj.2019-0026  
113.   Ishikawa Tomofumi, Obara Taku, Kikuchi Saya, et al. Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study. Journal of Affective Disorders. 2020; 264 : 295-303. doi:10.1016/j.jad.2020.01.016  
114.   Hozawa Atsushi. Screening for Aortic Aneurysm: Further Evidence is Required to Clarify the Issue. Journal of Atherosclerosis and Thrombosis. 2020; : . doi:10.5551/jat.ED143  
115.   Yoshida Makiko, Obara Taku, Kikuchi Saya, et al. Drug Prescriptions for Children With ADHD in Japan: A Study Based on Health Insurance Claims Data Between 2005 and 2015. Journal of Attention Disorders. 2020; 24 (2): 175-191. doi:10.1177/1087054719843179  
116.   Nishizawa Hironari, Matsumoto Mitsuyo, Shindo Tomohiko, et al. Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1. Journal of Biological Chemistry. 2020; 295 (1): 69-82. doi:10.1074/jbc.RA119.009548  
117.   Hishinuma Eiji, Gutiérrez Rico Evelyn, Hiratsuka Masahiro. In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase. Journal of Clinical Medicine. 2020; 9 (8): 2342. doi:10.3390/jcm9082342  
118.   Oba Mari S., Murakami Yoshitaka, Satoh Michihiro, et al. Examining the trimester-specific effects of low gestational weight gain on birthweight: the BOSHI study. Journal of Developmental Origins of Health and Disease. 2020; : 1-6. doi:10.1017/S2040174420000240  
119.   Sakurai Masaru, Ishizaki Masao, Morikawa Yuko, et al. Frequency of consumption of balanced meals, bodyweight gain and incident risk of glucose intolerance in Japanese men and women: A cohort study. Journal of Diabetes Investigation. 2020; : jdi.13392. doi:10.1111/jdi.13392  
120.   Itabashi Fumi, Hirata Takumi, Kogure Mana, et al. Combined associations of liver enzymes and obesity with diabetes mellitus prevalence: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200384  
121.   Yang Yunqing, Hozawa Atsushi, Kogure Mana, et al. Dietary Inflammatory Index Positively Associated With High-Sensitivity C-Reactive Protein Level in Japanese From NIPPON DATA2010. Journal of Epidemiology. 2020; 30 (2): 98-107. doi:10.2188/jea.JE20180156  
122.   Liu Ziyi, Zaid Maryam, Hisamatsu Takashi, et al. Elevated Fasting Blood Glucose Levels Are Associated With Lower Cognitive Function, With a Threshold in Non-Diabetic Individuals: A Population-Based Study. Journal of Epidemiology. 2020; 30 (3): 121-127. doi:10.2188/jea.JE20180193  
123.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200338  
124.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Social predictors of continued and indoor smoking among partners of non-smoking pregnant women: the TMM BirThree Cohort Study. Journal of Epidemiology. 2020; : . doi:10.2188/jea.JE20200313  
125.   Kakuta Yoichi, Izumiyama Yasuhiro, Okamoto Daisuke, et al. High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype. Journal of Gastroenterology. 2020; 55 (1): 67-77. doi:10.1007/s00535-019-01638-x  
126.   Aizawa Yayoi, Nagami Fuji, Ohashi Noriko, Kato Kazuto. A proposal on the first Japanese practical guidance for the return of individual genomic results in research settings. Journal of Human Genetics. 2020; 65 (3): 251-261. doi:10.1038/s10038-019-0697-y  
127.   Usuzaki Takuma, Ishikuro Mami, Murakami Keiko, et al. How can we evaluate whether an association is truly inter-generational?. Journal of Hypertension. 2020; 38 (9): 1866-1868. doi:10.1097/HJH.0000000000002507  
128.   Matsumoto Yuki, Misu Tatsuro, Mugikura Shunji, et al. Distinctive lesions of brain MRI between MOG-antibody-associated and AQP4-antibody-associated diseases. Journal of Neurology, Neurosurgery & Psychiatry. 2020; : jnnp-2020-324818. doi:10.1136/jnnp-2020-324818  
129.   Iwama Noriyuki, Ishikuro Mami, Tanaka Kosuke, et al. Epidemiological studies regarding hypertensive disorders of pregnancy: A review. Journal of Obstetrics and Gynaecology Research. 2020; 46 (9): 1672-1677. doi:10.1111/jog.14383  
130.   Li Lei, Nakano Daisuke, Zhang Anqi, et al. Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice. Journal of Pharmacological Sciences. 2020; 144 (4): 229-236. doi:10.1016/j.jphs.2020.09.004  
131.   Nishi Yasuhiro, Nomura Taro, Murakami Mamoru, et al. Effect of denture adhesives on oral moisture: A multicenter randomized controlled trial. Journal of Prosthodontic Research. 2020; 64 (3): 281-288. doi:10.1016/j.jpor.2019.08.004  
132.   Ohi Takashi, Komiyama Takamasa, Miyoshi Yoshitada, et al. The association between bilateral maximum occlusal force and all-cause mortality among community-dwelling older adults: The Tsurugaya project. Journal of Prosthodontic Research. 2020; 64 (3): 289-295. doi:10.1016/j.jpor.2019.08.005  
133.   Yaoita Nobuhiro, Satoh Kimio, Satoh Taijyu, et al. Identification of the Novel Variants in Patients With Chronic Thromboembolic Pulmonary Hypertension. Journal of the American Heart Association. 2020; 9 (21): . doi:10.1161/JAHA.120.015902  
134.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Association of iron levels in hair with brain structures and functions in young adults. Journal of Trace Elements in Medicine and Biology. 2020; 58 : 126436. doi:10.1016/j.jtemb.2019.126436  
135.   Jia Xiaoyuan, Yamamura Tomohiko, Gbadegesin Rasheed, et al. Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome. Kidney International. 2020; 98 (5): 1308-1322. doi:10.1016/j.kint.2020.05.029  
136.   Shirota Matsuyuki, Saigusa Daisuke, Yamashita Riu, et al. Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy. Medical Mass Spectrometry. 2020; 4 (1): 36-49. doi:10.24508/mms.2020.06.001  
137.   Kagaya Yuki, Minei Ryuhei, Duong Ha T T, et al. Metagenome Sequences from the Environment of Diseased Otter Clams, Lutraria rhynchaena, from a Farm in Vietnam. Microbiology Resource Announcements. 2020; 9 (2): . doi:10.1128/MRA.01068-19  
138.   Horiuchi Makoto, Taguchi Keiko, Hirose Wataru, et al. Cellular Nrf2 Levels Determine Cell Fate during Chemical Carcinogenesis in Esophageal Epithelium. Molecular and Cellular Biology. 2020; 41 (2): . doi:10.1128/MCB.00536-20  
139.   Baird Liam, Suzuki Takafumi, Takahashi Yushi, et al. Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2. Molecular and Cellular Biology. 2020; 40 (22): . doi:10.1128/MCB.00377-20  
140.   Otsuki Akihito, Okamura Yasunobu, Aoki Yuichi, et al. Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis. Molecular and Cellular Biology. 2020; 41 (2): . doi:10.1128/MCB.00472-20  
141.   Uruno Akira, Matsumaru Daisuke, Ryoke Rie, et al. Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice. Molecular and Cellular Biology. 2020; 40 (6): . doi:10.1128/MCB.00467-19  
142.   Baird Liam, Yamamoto Masayuki. NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer. Molecular and Cellular Biology. 2020; 41 (2): . doi:10.1128/MCB.00473-20  
143.   Baird Liam, Yamamoto Masayuki. The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway. Molecular and Cellular Biology. 2020; 40 (13): . doi:10.1128/MCB.00099-20  
144.   Mikami-Saito Yasuko, Maekawa Masamitsu, Wada Yoichi, et al. Essential oils can cause false-positive results of medium-chain acyl-CoA dehydrogenase deficiency. Molecular Genetics and Metabolism Reports. 2020; 25 : 100674. doi:10.1016/j.ymgmr.2020.100674  
145.   Waki Toshiyuki, Mameda Ryo, Nakano Takuya, et al. A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity. Nature Communications. 2020; 11 (1): 870. doi:10.1038/s41467-020-14558-9  
146.   Pradas-Juni Marta, Hansmeier Nils R., Link Jenny C., et al. A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nature Communications. 2020; 11 (1): 644. doi:10.1038/s41467-020-14323-y  
147.   Sargurupremraj Muralidharan, Suzuki Hideaki, Jian Xueqiu, et al. Cerebral small vessel disease genomics and its implications across the lifespan. Nature Communications. 2020; 11 (1): 6285. doi:10.1038/s41467-020-19111-2  
148.   Okazaki Keito, Anzawa Hayato, Liu Zun, et al. Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. Nature Communications. 2020; 11 (1): 5911. doi:10.1038/s41467-020-19593-0  
149.   Lin Yingsong, Nakatochi Masahiro, Hosono Yasuyuki, et al. Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Nature Communications. 2020; 11 (1): 3175. doi:10.1038/s41467-020-16711-w  
150.   Tsukada Kento, Shinki Shono, Kaneko Akiho, et al. Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones. Nature Communications. 2020; 11 (1): 1830. doi:10.1038/s41467-020-15664-4  
151.   Ishigaki Kazuyoshi, Akiyama Masato, Kanai Masahiro, et al. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature Genetics. 2020; 52 (7): 669-679. doi:10.1038/s41588-020-0640-3  
152.   Bai Wenjia, Suzuki Hideaki, Huang Jian, et al. A population-based phenome-wide association study of cardiac and aortic structure and function. Nature Medicine. 2020; 26 (10): 1654-1662. doi:10.1038/s41591-020-1009-y  
153.   Takeuchi Hikaru, Taki Yasuyuki, Matsudaira Izumi, et al. Convergent creative thinking performance is associated with white matter structures: Evidence from a large sample study. NeuroImage. 2020; 210 : 116577. doi:10.1016/j.neuroimage.2020.116577  
154.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Originality of divergent thinking is associated with working memory–related brain activity: Evidence from a large sample study. NeuroImage. 2020; 216 : 116825. doi:10.1016/j.neuroimage.2020.116825  
155.   Akaishi Tetsuya, Nakashima Ichiro, Takahashi Toshiyuki, et al. Neuromyelitis optica spectrum disorders with unevenly clustered attack occurrence. Neurology - Neuroimmunology Neuroinflammation. 2020; 7 (1): e640. doi:10.1212/NXI.0000000000000640  
156.   Sugiyama Mizuki, Nishijima Ichiko, Miyazaki Shota, Nakamura Takahiro J.. Secretin receptor-deficient mice exhibit altered circadian rhythm in wheel-running activity. Neuroscience Letters. 2020; 722 : 134814. doi:10.1016/j.neulet.2020.134814  
157.   Kaneyasu Tomoko, Mori Seiichi, Yamauchi Hideko, et al. Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome. npj Breast Cancer. 2020; 6 (1): 25. doi:10.1038/s41523-020-0163-1  
158.   Yonezawa Yudai, Obara Taku, Yamashita Takahiro, et al. Fruit and vegetable consumption before and during pregnancy and birth weight of new-borns in Japan: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 2020; 19 (1): 80. doi:10.1186/s12937-020-00595-z  
159.   Nakano Taiji, Ochiai Shingo, Suzuki Shuichi, et al. Breastfeeding promotes egg white sensitization in early infancy. Pediatric Allergy and Immunology. 2020; 31 (3): 315-318. doi:10.1111/pai.13208  
160.   Tanaka Toshiaki, Kato Noriko, Yokoya Susumu, et al. Changes in height standard deviation scores during early life are affected by nutrition. Pediatrics International. 2020; : ped.14577. doi:10.1111/ped.14577  
161.   Tsuchiya Masami, Obara Taku, Sakai Takamasa, et al. Quality evaluation of the Japanese Adverse Drug Event Report database (JADER). Pharmacoepidemiology and Drug Safety. 2020; 29 (2): 173-181. doi:10.1002/pds.4944  
162.   Ishiwata Ryosuke, Yaguchi Reo, Sugiyama Yuki. Correlations and responses for a system of n coupled linear oscillators with asymmetric interactions. Physical Review E. 2020; 102 (1): 012150. doi:10.1103/PhysRevE.102.012150  
163.   Matsuda Hinako, Nakayasu Masaru, Aoki Yuichi, et al. Diurnal metabolic regulation of isoflavones and soyasaponins in soybean roots. Plant Direct. 2020; 4 (11): . doi:10.1002/pld3.286  
164.   Okutani Fuki, Hamamoto Shoichiro, Aoki Yuichi, et al. Rhizosphere modelling reveals spatiotemporal distribution of daidzein shaping soybean rhizosphere bacterial community. Plant, Cell & Environment. 2020; 43 (4): 1036-1046. doi:10.1111/pce.13708  
165.   Kojima Kaname, Tadaka Shu, Katsuoka Fumiki, et al. A genotype imputation method for de-identified haplotype reference information by using recurrent neural network. PLOS Computational Biology. 2020; 16 (10): e1008207. doi:10.1371/journal.pcbi.1008207  
166.   Wada Yoichi, Kikuchi Atsuo, Kaga Akimune, et al. Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice. PLOS Genetics. 2020; 16 (2): e1008628. doi:10.1371/journal.pgen.1008628  
167.   Shimizu Sunao, Mimura Junsei, Hasegawa Takanori, et al. Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging. PLOS ONE. 2020; 15 (8): e0236834. doi:10.1371/journal.pone.0236834  
168.   Yanagisawa Kunio, Wichukchinda Nuanjun, Tsuchiya Naho, et al. Deficiency of mannose-binding lectin is a risk of Pneumocystis jirovecii pneumonia in a natural history cohort of people living with HIV/AIDS in Northern Thailand. PLOS ONE. 2020; 15 (12): e0242438. doi:10.1371/journal.pone.0242438  
169.   Miyagi Masaru, Wilson Rachel, Saigusa Daisuke, et al. Indole-3-acetic acid synthesized through the indole-3-pyruvate pathway promotes Candida tropicalis biofilm formation. PLOS ONE. 2020; 15 (12): e0244246. doi:10.1371/journal.pone.0244246  
170.   Miyagi Masaru, Wilson Rachel, Saigusa Daisuke, et al. Indole-3-acetic acid synthesized through the indole-3-pyruvate pathway promotes Candida tropicalis biofilm formation. PLOS ONE. 2020; 15 (12): e0244246. doi:10.1371/journal.pone.0244246  
171.   Oikawa Yoshitsugu, Izumi Rumiko, Koide Masashi, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLOS ONE. 2020; 15 (12): e0231064. doi:10.1371/journal.pone.0231064  
172.   Oikawa Yoshitsugu, Izumi Rumiko, Koide Masashi, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLOS ONE. 2020; 15 (12): e0231064. doi:10.1371/journal.pone.0231064  
173.   Oikawa Yoshitsugu, Izumi Rumiko, Koide Masashi, et al. Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5. PLOS ONE. 2020; 15 (12): e0231064. doi:10.1371/journal.pone.0231064  
174.   Wagata Maiko, Ishikuro Mami, Obara Taku, et al. Low birth weight and abnormal pre-pregnancy body mass index were at higher risk for hypertensive disorders of pregnancy. Pregnancy Hypertension. 2020; 22 : 119-125. doi:10.1016/j.preghy.2020.08.001  
175.   Takahashi Yuta, Takeuchi Hikaru, Sakai Mai, et al. A single nucleotide polymorphism (−250 A/C) of the GFAP gene is associated with brain structures and cerebral blood flow. Psychiatry and Clinical Neurosciences. 2020; 74 (1): 49-55. doi:10.1111/pcn.12932  
176.   Higuchi Yuji, Fujiwara Masaki, Nakaya Naoki, et al. Trends in smoking rates among individuals with serious psychological distress: Analysis of data from a Japanese national survey, 2007–2016. Psychiatry Research. 2020; 291 : 113225. doi:10.1016/j.psychres.2020.113225  
177.   Nagai Koshi, Uranbileg Baasanjav, Chen Zhen, et al. Identification of novel biomarkers of hepatocellular carcinoma by high‐definition mass spectrometry: Ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging. Rapid Communications in Mass Spectrometry. 2020; 34 (S1): rcm.8551. doi:10.1002/rcm.8551  
178.   Komatsu Hiroshi, Takeuchi Hikaru, Kikuchi Yoshie, et al. Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity. Schizophrenia Bulletin. 2020; 46 (6): 1619-1628. doi:10.1093/schbul/sbaa049  
179.   Oka Yasuyoshi, Hamada Motoharu, Nakazawa Yuka, et al. Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome. Science Advances. 2020; 6 (51): eabd7197. doi:10.1126/sciadv.abd7197  
180.   Kakuta Yoichi, Ichikawa Ryo, Fuyuno Yuta, et al. An Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn’s Disease in Japanese Populations. Scientific Reports. 2020; 10 (1): 10236. doi:10.1038/s41598-020-66951-5  
181.   Nishizawa Ayako, Kumada Kazuki, Tateno Keiko, et al. Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia. Scientific Reports. 2020; 10 (1): 20027. doi:10.1038/s41598-020-77081-3  
182.   Kim Yong Woo, Kim Yu Jeong, Cheong Hyun Sub, et al. Exploring the Novel Susceptibility Gene Variants for Primary Open-Angle Glaucoma in East Asian Cohorts: The GLAU-GENDISK Study. Scientific Reports. 2020; 10 (1): 221. doi:10.1038/s41598-019-57066-7  
183.   Kumondai Masaki, Hishinuma Eiji, Gutiérrez Rico Evelyn Marie, et al. Heterologous expression of high-activity cytochrome P450 in mammalian cells. Scientific Reports. 2020; 10 (1): 14193. doi:10.1038/s41598-020-71035-5  
184.   Sakai Kensuke, Tanikawa Chizu, Hirasawa Akira, et al. Identification of a novel uterine leiomyoma GWAS locus in a Japanese population. Scientific Reports. 2020; 10 (1): 1197. doi:10.1038/s41598-020-58066-8  
185.   Takahashi Yuta, Yoshizoe Kazuki, Ueki Masao, et al. Machine learning to reveal hidden risk combinations for the trajectory of posttraumatic stress disorder symptoms. Scientific Reports. 2020; 10 (1): 21726. doi:10.1038/s41598-020-78966-z  
186.   Rashad Sherif, Saigusa Daisuke, Yamazaki Takahiro, et al. Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach. Scientific Reports. 2020; 10 (1): 6507. doi:10.1038/s41598-020-63483-w  
187.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Succeeding in deactivating: associations of hair zinc levels with functional and structural neural mechanisms. Scientific Reports. 2020; 10 (1): 12364. doi:10.1038/s41598-020-69277-4  
188.   Takeuchi Hikarua, Taki Yasuyuki, Nouchi Rui, et al. The associations of BMI with mean diffusivity of basal ganglia among young adults with mild obesity and without obesity. Scientific Reports. 2020; 10 (1): 12566. doi:10.1038/s41598-020-69438-5  
189.   Amano Ryota, Karashima Akihiro, Motoike Ikuko, et al. Consistency index of daily activity pattern and its correlations with subjective ratings of QOL. Sleep and Biological Rhythms. 2020; 18 (4): 297-304. doi:10.1007/s41105-020-00271-z  
190.   Utsumi Yusuke, Nemoto Harumi, Nakaya Naoki, et al. The Impact of Health Consciousness on the Association Between Walking Durations and Mental Health Conditions After a Disaster: a Cross-Sectional Study. Sports Medicine - Open. 2020; 6 (1): 30. doi:10.1186/s40798-020-00259-6  
191.   Fukunaga Hisanori, Matsuya Yusuke, Tokuuye Koichi, Omura Motoko. Implications of radiation microdosimetry for accelerator-based boron neutron capture therapy: a radiobiological perspective. The British Journal of Radiology. 2020; 93 (1111): 20200311. doi:10.1259/bjr.20200311  
192.   Usuzaki Takuma, Ishikuro Mami, Metoki Hirohito, et al. Comparison among research, home, and office blood pressure measurements for pregnant women: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2020; 22 (11): 2004-2013. doi:10.1111/jch.14050  
193.   Kikuchi Daisuke, Obara Taku, Usuzaki Takuma, et al. Evaluating folic acid supplementation among Japanese pregnant women with dietary intake of folic acid lower than 480 µg per day: results from TMM BirThree Cohort Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2020; : 1-6. doi:10.1080/14767058.2020.1739020  
194.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Mother-to-infant bonding failure and intimate partner violence during pregnancy as risk factors for father-to-infant bonding failure at 1 month postpartum: an adjunct study of the Japan Environment and Children’s Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2020; 33 (16): 2789-2796. doi:10.1080/14767058.2018.1560414  
195.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. The prevalence and risk factors for postpartum depression symptoms of fathers at one and 6 months postpartum: an adjunct study of the Japan Environment & Children’s Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2020; 33 (16): 2797-2804. doi:10.1080/14767058.2018.1560415  
196.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Update on the prevalence and determinants of folic acid use in Japan evaluated with 91,538 pregnant women: the Japan Environment and Children’s Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2020; 33 (3): 427-436. doi:10.1080/14767058.2018.1494712  
197.   Fujita Ayami, Hara Azusa, Kikuya Masahiro, et al. Blood Pressure Phenotypes Defined by Ambulatory Blood Pressure Monitoring and Carotid Artery Changes in Community-Dwelling Older Japanese Adults: The Ohasama Study. The Tohoku Journal of Experimental Medicine. 2020; 252 (3): 269-279. doi:10.1620/tjem.252.269  
198.   Tsuboi Akito, Matsui Hiroyuki, Shiraishi Naru, et al. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 251 (2): 97-115. doi:10.1620/tjem.251.97  
199.   Nagami Fuji, Kuriki Miho, Koreeda Sachie, et al. Public Relations and Communication Strategies in Construction of Large-Scale Cohorts and Biobank: Practice in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 250 (4): 253-262. doi:10.1620/tjem.250.253  
200.   Yamakage Shu, Oe Yuji, Sekimoto Akiyo, et al. Protease-activated receptor 2 contributes to placental development and fetal growth in mice. Thrombosis Research. 2020; 193 : 173-179. doi:10.1016/j.thromres.2020.06.039  
201.   Oe Yuji, Sato Emiko, Sato Hiroshi, et al. Uremic toxins alter coagulation and fibrinolysis-related genes expression in human endothelial cells. Thrombosis Research. 2020; 186 : 75-77. doi:10.1016/j.thromres.2019.12.017  
202.   Narita Akira, Nagai Masato, Mizuno Satoshi, et al. Clustering by phenotype and genome-wide association study in autism. Translational Psychiatry. 2020; 10 (1): 290. doi:10.1038/s41398-020-00951-x  
203.   Takahashi Yuta, Ueki Masao, Yamada Makoto, et al. Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection. Translational Psychiatry. 2020; 10 (1): 157. doi:10.1038/s41398-020-0831-9  
204.   Takahashi Yuta, Ueki Masao, Tamiya Gen, et al. Machine learning for effectively avoiding overfitting is a crucial strategy for the genetic prediction of polygenic psychiatric phenotypes. Translational Psychiatry. 2020; 10 (1): 294. doi:10.1038/s41398-020-00957-5  
205.   Noda Aoi, Sakai Takamasa, Tsuchiya Masami, et al. Characteristics of Adverse Events Following Immunization Reporting in Children: The Japanese Adverse Drug Event Report Database. Vaccines. 2020; 8 (3): 357. doi:10.3390/vaccines8030357  
206.   田原 康玄, 寳澤 篤, 小暮 真奈. 本態性高血圧のリスク因子としてのナトリウム/カリウム(N a / K)比. 日本循環器病予防学会誌. 2020; 55 (2): 114-123.  
207.   Nakaya Naoki, Sone Toshimasa, Tomata Yasutake, et al. All-cause mortality among Japanese whose cohabiting partners are diagnosed with cancer: the Ohsaki Cohort 2006 study. Acta Oncologica. 2019; 58 (4): 425-431. doi:10.1080/0284186X.2018.1562208  
208.   Watanabe Mari, Oe Yuji, Sato Emiko, et al. Protease-activated receptor 2 exacerbates cisplatin-induced nephrotoxicity. American Journal of Physiology-Renal Physiology. 2019; 316 (4): F654-F659. doi:10.1152/ajprenal.00489.2018  
209.   Saigusa Daisuke, Saito Ritsumi, Kawamoto Komei, et al. Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Analytical Chemistry. 2019; 91 (14): 8979-8986. doi:10.1021/acs.analchem.9b01159  
210.   Iwasawa Shinya, Yanagi Kumiko, Kikuchi Atsuo, et al. Recurrent de novo MAPK8IP3 variants cause neurological phenotypes. Annals of Neurology. 2019; 85 (6): 927-933. doi:10.1002/ana.25481  
211.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. Is Additional Surgery Always Sufficient for Preventing Recurrence After Endoscopic Submucosal Dissection with Curability C-2 for Early Gastric Cancer?. Annals of Surgical Oncology. 2019; 26 (11): 3636-3643. doi:10.1245/s10434-019-07579-2  
212.   Isojima Tsuyoshi, Kato Noriko, Yokoya Susumu, et al. Early excessive growth with distinct seasonality in preschool obesity. Archives of Disease in Childhood. 2019; 104 (1): 53-57. doi:10.1136/archdischild-2018-314862  
213.   Imaruoka Kenta, Oe Yuji, Fushima Tomofumi, et al. Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide. Biochemical and Biophysical Research Communications. 2019; 510 (4): 587-593. doi:10.1016/j.bbrc.2019.01.110  
214.   Akatsuka Jun, Yamamoto Yoichiro, Sekine Tetsuro, et al. Illuminating Clues of Cancer Buried in Prostate MR Image: Deep Learning and Expert Approaches. Biomolecules. 2019; 9 (11): 673. doi:10.3390/biom9110673  
215.   Keleku-Lukwete Nadine, Suzuki Mikiko, Panda Harit, et al. Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice. Blood Advances. 2019; 3 (8): 1285-1297. doi:10.1182/bloodadvances.2018017574  
216.   Miyahara Reiko, Piyaworawong Surachai, Naranbhai Vivek, et al. Predicting the risk of pulmonary tuberculosis based on the neutrophil-to-lymphocyte ratio at TB screening in HIV-infected individuals. BMC Infectious Diseases. 2019; 19 (1): 667. doi:10.1186/s12879-019-4292-9  
217.   Sakurai-Yageta Mika, Kawame Hiroshi, Kuriyama Shinichi, et al. A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization. BMC Medical Education. 2019; 19 (1): 297. doi:10.1186/s12909-019-1725-5  
218.   Kubo Sachimi, Nishida Yoko, Kubota Yoshimi, et al. Higher serum uric acid level is inversely associated with renal function assessed by cystatin C in a Japanese general population without chronic kidney disease: the KOBE study. BMC Nephrology. 2019; 20 (1): 117. doi:10.1186/s12882-019-1291-4  
219.   Higuchi Yuji, Fujiwara Masaki, Nakaya Naoki, et al. Change in smoking cessation stage over 1 year in patients with schizophrenia: a follow up study in Japan. BMC Psychiatry. 2019; 19 (1): 367. doi:10.1186/s12888-019-2351-9  
220.   Nakagawa Seishu, Sugiura Motoaki, Sekiguchi Atsushi, et al. The pitfall of empathic concern with chronic fatigue after a disaster in young adults. BMC Psychiatry. 2019; 19 (1): 338. doi:10.1186/s12888-019-2323-0  
221.   Murakami Keiko, Hashimoto Hideki. Associations of education and income with heavy drinking and problem drinking among men: evidence from a population-based study in Japan. BMC Public Health. 2019; 19 (1): 420. doi:10.1186/s12889-019-6790-5  
222.   Fujiwara Masaki, Inagaki Masatoshi, Shimazu Taichi, et al. A randomised controlled trial of a case management approach to encourage participation in colorectal cancer screening for people with schizophrenia in psychiatric outpatient clinics: study protocol for the J-SUPPORT 1901 (ACCESS) study. BMJ Open. 2019; 9 (11): e032955. doi:10.1136/bmjopen-2019-032955  
223.   Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): e025939. doi:10.1136/bmjopen-2018-025939  
224.   Ikeda Shigeyuki, Takeuchi Hikaru, Taki Yasuyuki, et al. Neural substrates of self‐ and external‐preoccupation: A voxel‐based morphometry study. Brain and Behavior. 2019; 9 (6): e01267. doi:10.1002/brb3.1267  
225.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Association of copper levels in the hair with gray matter volume, mean diffusivity, and cognitive functions. Brain Structure and Function. 2019; 224 (3): 1203-1217. doi:10.1007/s00429-019-01830-y  
226.   Kuniyoshi Yasutaka, Kikuya Masahiro, Matsubara Hiroko, et al. Association of Feeding Practice with Childhood Overweight and/or Obesity in Affected Areas Before and After the Great East Japan Earthquake. Breastfeeding Medicine. 2019; 14 (6): 382-389. doi:10.1089/bfm.2018.0254  
227.   Harada Nobuhiko, Hasegawa Atsushi, Hirano Ikuo, et al. GATA 2 hypomorphism induces chronic myelomonocytic leukemia in mice. Cancer Science. 2019; 110 (4): 1183-1193. doi:10.1111/cas.13959  
228.   Suzuki Takafumi, Muramatsu Aki, Saito Ryota, et al. Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1. Cell Reports. 2019; 28 (3): 746-758.e4. doi:10.1016/j.celrep.2019.06.047  
229.   Hitomi Yuki, Nakatani Ken, Kojima Kaname, et al. NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants. Cellular and Molecular Gastroenterology and Hepatology. 2019; 7 (3): 515-532. doi:10.1016/j.jcmgh.2018.11.006  
230.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. A Common CACNA1C Gene Risk Variant has Sex-Dependent Effects on Behavioral Traits and Brain Functional Activity. Cerebral Cortex. 2019; 29 (8): 3211-3219. doi:10.1093/cercor/bhy189  
231.   Nishikawa Tomofumi, Miyamatsu Naomi, Higashiyama Aya, et al. Daily Habit of Water Intake in Patients with Cerebral Infarction before its Onset; Comparison with a Healthy Population: A Cross-Sectional Study. Cerebrovascular Diseases. 2019; 47 (3-4): 143-150. doi:10.1159/000500075  
232.   Kondo Keiko, Miura Katsuyuki, Tanaka-Mizuno Sachiko, et al. Cardiovascular Risk Assessment Chart by Dietary Factors in Japan ― NIPPON DATA80 ―. Circulation Journal. 2019; 83 (6): 1254-1260. doi:10.1253/circj.CJ-18-1002  
233.   Kurosawa Ryo, Satoh Kimio, Kikuchi Nobuhiro, et al. Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension. Circulation Research. 2019; 125 (3): 309-327. doi:10.1161/CIRCRESAHA.119.315229  
234.   Ishizawa Kota, Yamanaka Mie, Saiki Yuriko, et al. CD45 + CD326 + Cells are Predictive of Poor Prognosis in Non–Small Cell Lung Cancer Patients. Clinical Cancer Research. 2019; 25 (22): 6756-6763. doi:10.1158/1078-0432.CCR-19-0545  
235.   Murakami Keiko, Aida Jun, Hashimoto Hideki. Associations of social relationships with curative and preventive dental care use among young and middle‐aged adults: Evidence from a population‐based study in Japan. Community Dentistry and Oral Epidemiology. 2019; 47 (5): 389-397. doi:10.1111/cdoe.12487  
236.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Preconception folic acid supplementation use and the occurrence of neural tube defects in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study. Congenital Anomalies. 2019; 59 (4): 110-117. doi:10.1111/cga.12293  
237.   Yamada Hiroyuki, Doi Kent, Tsukamoto Tatsuo, et al. Low-dose atrial natriuretic peptide for prevention or treatment of acute kidney injury: a systematic review and meta-analysis. Critical Care. 2019; 23 (1): 41. doi:10.1186/s13054-019-2330-z  
238.   Hatta Waku, Koike Tomoyuki, Okata Hideki, et al. Continuous liquid-suction catheter attachment for endoscope reduces volume of liquid reflux to the mouth in esophageal endoscopic submucosal dissection. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2019; 31 (5): 527-534. doi:10.1111/den.13392  
239.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Disaster Medicine and Public Health Preparedness. 2019; 13 (5-6): 905-911. doi:10.1017/dmp.2019.8  
240.   Shimizu Makiko, Yoda Hiromi, Nakakuki Komei, et al. Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database. Drug Metabolism and Pharmacokinetics. 2019; 34 (5): 334-339. doi:10.1016/j.dmpk.2019.06.001  
241.   Akiyama Tetsuya, Suzuki Naoki, Ishikawa Mitsuru, et al. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons. EBioMedicine. 2019; 45 : 362-378. doi:10.1016/j.ebiom.2019.06.013  
242.   Itoi Keiichi, Motoike Ikuko, Liu Ying, et al. Genome-Wide Analysis of Glucocorticoid-Responsive Transcripts in the Hypothalamic Paraventricular Region of Male Rats. Endocrinology. 2019; 160 (1): 38-54. doi:10.1210/en.2018-00535  
243.   Nakamura Mieko, Ojima Toshiyuki, Nagahata Tomomi, et al. Having few remaining teeth is associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese individuals: findings from the NIPPON DATA2010. Environmental Health and Preventive Medicine. 2019; 24 (1): 1. doi:10.1186/s12199-018-0752-x  
244.   Panda Harit, Keleku-Lukwete Nadine, Kuga Ayumi, et al. Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model. Experimental Hematology. 2019; 77 : 51-60.e1. doi:10.1016/j.exphem.2019.08.001  
245.   Akaishi Tetsuya, Onishi Eiko, Abe Michiaki, et al. The human central nervous system discharges carbon dioxide and lactic acid into the cerebrospinal fluid. Fluids and Barriers of the CNS. 2019; 16 (1): 8. doi:10.1186/s12987-019-0128-7  
246.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. The Effects of Family Socioeconomic Status on Psychological and Neural Mechanisms as Well as Their Sex Differences. Frontiers in Human Neuroscience. 2019; 12 : 543. doi:10.3389/fnhum.2018.00543  
247.   Manome Ayumi, Abiko Yuki, Kawashima Junko, et al. Acidogenic Potential of Oral Bifidobacterium and Its High Fluoride Tolerance. Frontiers in Microbiology. 2019; 10 : 1099. doi:10.3389/fmicb.2019.01099  
248.   Yamada Shinya, Hatta Waku, Shimosegawa Tooru, et al. Different risk factors between early and late cancer recurrences in patients without additional surgery after noncurative endoscopic submucosal dissection for early gastric cancer. Gastrointestinal Endoscopy. 2019; 89 (5): 950-960. doi:10.1016/j.gie.2018.11.015  
249.   Shimanoe C, Hachiya T, Hara M, et al. A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Genes, Brain and Behavior. 2019; 18 (2): e12481. doi:10.1111/gbb.12481  
250.   Wada Yoichi, Kikuchi Atsuo, Arai-Ichinoi Natsuko, et al. Biallelic GALM pathogenic variants cause a novel type of galactosemia. Genetics in Medicine. 2019; 21 (6): 1286-1294. doi:10.1038/s41436-018-0340-x  
251.   Sone Toshimasa, Nakaya Naoki, Tomata Yasutake, et al. Spouse's functional disability and mortality: The Ohsaki Cohort 2006 Study. Geriatrics & Gerontology International. 2019; 19 (8): 774-779. doi:10.1111/ggi.13709  
252.   Mori Minako, Hira Asuka, Yoshida Kenichi, et al. Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica. 2019; 104 (10): 1962-1973. doi:10.3324/haematol.2018.207241  
253.   Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7  
254.   Tadaka Shu, Katsuoka Fumiki, Ueki Masao, et al. 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. Human Genome Variation. 2019; 6 (1): 28. doi:10.1038/s41439-019-0059-5  
255.   Nagasaki Masao, Kuroki Yoko, Shibata Tomoko F., et al. Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. Human Genome Variation. 2019; 6 (1): 27. doi:10.1038/s41439-019-0057-7  
256.   Wang Yen-Yen, Mimori Takahiro, Khor Seik-Soon, et al. HLA-VBSeq v2: improved HLA calling accuracy with full-length Japanese class-I panel. Human Genome Variation. 2019; 6 (1): 29. doi:10.1038/s41439-019-0061-y  
257.   Misawa Kazuharu, Watanabe Hiroshi, Yokoseki Akio, et al. Is the population of Sado Island genetically close to the population of western Japan?. Human Genome Variation. 2019; 6 (1): 26. doi:10.1038/s41439-019-0058-6  
258.   Fukunaga Hisanori, Taki Yasuyuki, Prise Kevin M. Diversity of ATM gene variants: a population-based genome data analysis for precision medicine. Human Genomics. 2019; 13 (1): 38. doi:10.1186/s40246-019-0234-2  
259.   Yu Yujiao, Nakagawa Tadashi, Morohoshi Akane, et al. Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity. Human Molecular Genetics. 2019; 28 (20): 3486-3497. doi:10.1093/hmg/ddz119  
260.   Fujishima Fumiyoshi, Katsushima Hiroki, Fukuhara Noriko, et al. Immunohistochemical pattern of c-MYC protein judged as “+/(weak)+/−” by a new notation correlates with MYC gene nontranslocation in large B-cell lymphoma. Human Pathology. 2019; 85 : 112-118. doi:10.1016/j.humpath.2018.10.025  
261.   Li Yan, Thijs Lutgarde, Zhang Zhen-Yu, et al. Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure. Hypertension. 2019; 74 (6): 1333-1342. doi:10.1161/HYPERTENSIONAHA.119.12958  
262.   Iwama Noriyuki, Metoki Hirohito, Nishigori Hidekazu, et al. Association between alcohol consumption during pregnancy and hypertensive disorders of pregnancy in Japan: the Japan Environment and Children’s Study. Hypertension Research. 2019; 42 (1): 85-94. doi:10.1038/s41440-018-0124-3  
263.   Tanaka Kosuke, Nishigori Hidekazu, Watanabe Zen, et al. Higher prevalence of hypertensive disorders of pregnancy in women who smoke: the Japan environment and children’s study. Hypertension Research. 2019; 42 (4): 558-566. doi:10.1038/s41440-019-0206-x  
264.   Akaishi Tetsuya, Kiyomoto Hideyasu, Abe Michiaki, et al. A 29-year-old Woman with Recurrent Pregnancy-induced Hypertension Based on Vascular Compression of the Medulla Oblongata. Internal Medicine. 2019; 58 (15): 2257-2261. doi:10.2169/internalmedicine.2382-18  
265.   Dissanayake Eishika, Tani Yumi, Nagai Kazue, et al. Skin Care and Synbiotics for Prevention of Atopic Dermatitis or Food Allergy in Newborn Infants: A 2 × 2 Factorial, Randomized, Non-Treatment Controlled Trial. International Archives of Allergy and Immunology. 2019; 180 (3): 202-211. doi:10.1159/000501636  
266.   Sato Tomonori, Kawasaki Yoshihide, Maekawa Masamitsu, et al. Value of global metabolomics in association with diagnosis and clinicopathological factors of renal cell carcinoma. International Journal of Cancer. 2019; 145 (2): 484-493. doi:10.1002/ijc.32115  
267.   Nishikawa Tomofumi, Miyamatsu Naomi, Higashiyama Aya, et al. Being Conscious of Water Intake Positively Associated with Sufficient Non-Alcohol Drink Intake Regardless of Seasons and Reasons in Healthy Japanese; the KOBE Study: A Cross Sectional Study. International Journal of Environmental Research and Public Health. 2019; 16 (21): 4151. doi:10.3390/ijerph16214151  
268.   Sakurai Rieko, Ueki Masao, Makino Satoshi, et al. Outlier detection for questionnaire data in biobanks. International Journal of Epidemiology. 2019; 48 (4): 1305-1315. doi:10.1093/ije/dyz012  
269.   Maekawa Masamitsu, Jinnoh Isamu, Matsumoto Yotaro, et al. Structural Determination of Lysosphingomyelin-509 and Discovery of Novel Class Lipids from Patients with Niemann-Pick Disease Type C. International journal of molecular sciences. 2019; 20 (20): 5018. doi:10.3390/ijms20205018  
270.   Suzuki Hideaki, Venkataraman Ashwin V, Bai Wenjia, et al. Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance. JAMA Network Open. 2019; 2 (12): e1917257. doi:10.1001/jamanetworkopen.2019.17257  
271.   Fuse Nobuo, Sakurai-Yageta Mika, Katsuoka Fumiki, et al. Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project. JMA Journal. 2019; 2 (2): 113-122. doi:10.31662/jmaj.2019-0014  
272.   Tayama J, Ogawa S, Nakaya N, et al. Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial. Journal of Affective Disorders. 2019; 245 : 364-370. doi:10.1016/j.jad.2018.11.039  
273.   Watanabe Zen, Nishigori Hidekazu, Tanoue Kaou, et al. Preconception dysmenorrhea as a risk factor for psychological distress in pregnancy: The Japan Environment and Children's Study. Journal of Affective Disorders. 2019; 245 : 475-483. doi:10.1016/j.jad.2018.11.061  
274.   Kakuta Yoichi, Kawai Yosuke, Naito Takeo, et al. A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn’s Disease in Japanese Individuals. Journal of Crohn's and Colitis. 2019; 13 (5): 648-658. doi:10.1093/ecco-jcc/jjy197  
275.   Kiniwa Yukiko, Yasuda Jun, Saito Sakae, et al. Identification of genetic alterations in extramammary Paget disease using whole exome analysis. Journal of Dermatological Science. 2019; 94 (1): 229-235. doi:10.1016/j.jdermsci.2019.03.006  
276.   Takagi K, Iwama N, Metoki H, et al. Paternal height has an impact on birth weight of their offspring in a Japanese population: the Japan Environment and Children’s Study. Journal of Developmental Origins of Health and Disease. 2019; 10 (5): 542-554. doi:10.1017/S2040174418001162  
277.   Hozawa Atsushi, Hirata Takumi, Yatsuya Hiroshi, et al. Association Between Body Mass Index and All-Cause Death in Japanese Population: Pooled Individual Participant Data Analysis of 13 Cohort Studies. Journal of Epidemiology. 2019; 29 (12): 457-463. doi:10.2188/jea.JE20180124  
278.   Sumi Masaki, Hisamatsu Takashi, Fujiyoshi Akira, et al. Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA). Journal of Epidemiology. 2019; 29 (6): 205-212. doi:10.2188/jea.JE20170191  
279.   Shibata Yosuke, Ojima Toshiyuki, Nakamura Mieko, et al. Associations of Overweight, Obesity, and Underweight With High Serum Total Cholesterol Level Over 30 Years Among the Japanese Elderly: NIPPON DATA 80, 90, and 2010. Journal of Epidemiology. 2019; 29 (4): 133-138. doi:10.2188/jea.JE20170229  
280.   Igarashi Ayaka, Aida Jun, Sairenchi Toshimi, et al. Does Cigarette Smoking Increase Traffic Accident Death During 20 Years Follow-up in Japan? The Ibaraki Prefectural Health Study. Journal of Epidemiology. 2019; 29 (5): 192-196. doi:10.2188/jea.JE20170330  
281.   Kusama Taro, Aida Jun, Sugiyama Kemmyo, et al. Does the Type of Temporary Housing Make a Difference in Social Participation and Health for Evacuees of the Great East Japan Earthquake and Tsunami? A Cross-Sectional Study. Journal of Epidemiology. 2019; 29 (10): 391-398. doi:10.2188/jea.JE20180080  
282.   Mizuguchi Takeshi, Suzuki Takeshi, Abe Chihiro, et al. A 12-kb structural variation in progressive myoclonic epilepsy was newly identified by long-read whole-genome sequencing. Journal of Human Genetics. 2019; 64 (5): 359-368. doi:10.1038/s10038-019-0569-5  
283.   Satoh Atsushi, Arima Hisatomi, Hozawa Atsushi, et al. The association of home and accurately measured office blood pressure with coronary artery calcification among general Japanese men. Journal of Hypertension. 2019; 37 (8): 1676-1681. doi:10.1097/HJH.0000000000002080  
284.   Numakura Chikahiko, Tamiya Gen, Ueki Masao, et al. Growth impairment in individuals with citrin deficiency. Journal of Inherited Metabolic Disease. 2019; 42 (3): 501-508. doi:10.1002/jimd.12051  
285.   Tanoue Kaou, Nishigori Hidekazu, Watanabe Zen, et al. Interannual Changes in the Prevalence of Intimate Partner Violence Against Pregnant Women in Miyagi Prefecture After the Great East Japan Earthquake: The Japan Environment and Children’s Study. Journal of Interpersonal Violence. 2019; : 088626051988151. doi:10.1177/0886260519881517  
286.   Shido Kosuke, Kojima Kaname, Yamasaki Kenshi, et al. Susceptibility Loci for Tanning Ability in the Japanese Population Identified by a Genome-Wide Association Study from the Tohoku Medical Megabank Project Cohort Study. Journal of Investigative Dermatology. 2019; 139 (7): 1605-1608.e13. doi:10.1016/j.jid.2019.01.015  
287.   Maekawa Masamitsu, Jinnoh Isamu, Narita Aya, et al. Investigation of diagnostic performance of five urinary cholesterol metabolites for Niemann-Pick disease type C. Journal of Lipid Research. 2019; 60 (12): 2074-2081. doi:10.1194/jlr.M093971  
288.   Fujita Takaaki, Sato Atsushi, Narita Akira, et al. Use of a multilayer perceptron to create a prediction model for dressing independence in a small sample at a single facility. Journal of Physical Therapy Science. 2019; 31 (1): 69-74. doi:10.1589/jpts.31.69  
289.   Satoh Michihiro, Metoki Hirohito, Asayama Kei, et al. Age‐Related Trends in Home Blood Pressure, Home Pulse Rate, and Day‐to‐Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study. Journal of the American Heart Association. 2019; 8 (15): e012121. doi:10.1161/JAHA.119.012121  
290.   Tanikawa Chizu, Kamatani Yoichiro, Terao Chikashi, et al. Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population. Journal of the American Society of Nephrology. 2019; 30 (5): 855-864. doi:10.1681/ASN.2018090942  
291.   Hashimoto Taeko, Harita Yutaka, Takizawa Keiichi, et al. In Vivo Expression of NUP93 and Its Alteration by NUP93 Mutations Causing Focal Segmental Glomerulosclerosis. Kidney International Reports. 2019; 4 (9): 1312-1322. doi:10.1016/j.ekir.2019.05.1157  
292.   Wang Jiao, Kano Kuniyuki, Saigusa Daisuke, Aoki Junken. Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection. Mass Spectrometry. 2019; 8 (1): A0072-A0072. doi:10.5702/massspectrometry.A0072  
293.   Izumi Yoshihiro, Matsuda Fumio, Hirayama Akiyoshi, et al. Inter-Laboratory Comparison of Metabolite Measurements for Metabolomics Data Integration. Metabolites. 2019; 9 (11): 257. doi:10.3390/metabo9110257  
294.   Katsuoka Fumiki, Otsuki Akihito, Takahashi Mizue, et al. Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells. Molecular and Cellular Biology. 2019; 39 (20): . doi:10.1128/MCB.00273-19  
295.   Iwasawa Shinya, Kikuchi Atsuo, Wada Yoichi, et al. The prevalence of GALM mutations that cause galactosemia: A database of functionally evaluated variants. Molecular Genetics and Metabolism. 2019; 126 (4): 362-367. doi:10.1016/j.ymgme.2019.01.018  
296.   Takata Ryo, Takahashi Atsushi, Fujita Masashi, et al. 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. Nature Communications. 2019; 10 (1): 4422. doi:10.1038/s41467-019-12267-6  
297.   Nikopoulos Konstantinos, Cisarova Katarina, Quinodoz Mathieu, et al. A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy. Nature Communications. 2019; 10 (1): 2884. doi:10.1038/s41467-019-10746-4  
298.   Yamamoto Yoichiro, Tsuzuki Toyonori, Akatsuka Jun, et al. Automated acquisition of explainable knowledge from unannotated histopathology images. Nature Communications. 2019; 10 (1): 5642. doi:10.1038/s41467-019-13647-8  
299.   Akiyama Masato, Ishigaki Kazuyoshi, Sakaue Saori, et al. Characterizing rare and low-frequency height-associated variants in the Japanese population. Nature Communications. 2019; 10 (1): 4393. doi:10.1038/s41467-019-12276-5  
300.   Kikuchi Koichi, Saigusa Daisuke, Kanemitsu Yoshitomi, et al. Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. Nature Communications. 2019; 10 (1): 1835. doi:10.1038/s41467-019-09735-4  
301.   Suzuki Ken, Akiyama Masato, Ishigaki Kazuyoshi, et al. Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. Nature Genetics. 2019; 51 (3): 379-386. http://www.nature.com/articles/s41588-018-0332-4  
302.   Ishiura Hiroyuki, Shibata Shota, Yoshimura Jun, et al. Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease. Nature Genetics. 2019; 51 (8): 1222-1232. doi:10.1038/s41588-019-0458-z  
303.   Evangelou Evangelos, Gao He, Chu Congying, et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. 2019; 3 (9): 950-961. doi:10.1038/s41562-019-0653-z  
304.   Nanto-Hara Fumika, Kanemitsu Yoshitomi, Fukuda Shinji, et al. The guanylate cyclase C agonist linaclotide ameliorates the gut–cardio–renal axis in an adenine-induced mouse model of chronic kidney disease. Nephrology Dialysis Transplantation. 2019; : . doi:10.1093/ndt/gfz126  
305.   Tanaka Asahi, Arai Yasumichi, Hirata Takumi, et al. Effects of polypharmacy and anticholinergic/sedative drugs on the physical/cognitive/mental related outcomes of community-dwelling elderly people: The Kawasaki Wellbeing Project. Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2019; 56 (4): 504-515. doi:10.3143/geriatrics.56.504  
306.   Obayashi Takeshi, Kagaya Yuki, Aoki Yuichi, et al. COXPRESdb v7: a gene coexpression database for 11 animal species supported by 23 coexpression platforms for technical evaluation and evolutionary inference. Nucleic Acids Research. 2019; 47 (D1): D55-D62. doi:10.1093/nar/gky1155  
307.   Morita Masahiko, Shimokawa Kazuro, Nishimura Masaomi, et al. ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks. Nucleic Acids Research. 2019; 47 (D1): D859-D866. doi:10.1093/nar/gky951  
308.   Murakami Mamoru, Nishi Yasuhiro, Harada Kae, et al. Impact of Oral Intake of Glucosylceramide Extracted from Pineapple on Xerostomia: A Double-Blind Randomized Cross-Over Trial. Nutrients. 2019; 11 (9): 2020. doi:10.3390/nu11092020  
309.   Nishi Daisuke, Su Kuan-Pin, Usuda Kentaro, et al. Differences between Japan and Taiwan in the treatment of pregnant women with depressive symptoms by omega-3 fatty acids: An open-label pilot study. Nutritional Neuroscience. 2019; 22 (1): 63-71. doi:10.1080/1028415X.2017.1354540  
310.   Amano Yuji, Akazawa Yohei, Yasuda Jun, et al. A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease. Pediatric Rheumatology. 2019; 17 (1): 34. doi:10.1186/s12969-019-0337-2  
311.   Ishikawa Tomofumi, Obara Taku, Jin Kazutaka, et al. Examination of the prescription of antiepileptic drugs to prenatal and postpartum women in Japan from a health administrative database. Pharmacoepidemiology and Drug Safety. 2019; 28 (6): 804-811. doi:10.1002/pds.4749  
312.   Ueki Masao, Fujii Masahiro, Tamiya Gen. Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies. PLOS ONE. 2019; 14 (7): e0219825. doi:10.1371/journal.pone.0219825  
313.   Matsudaira Izumi, Oba Kentaro, Takeuchi Hikaru, et al. rs1360780 of the FKBP5 gene modulates the association between maternal acceptance and regional gray matter volume in the thalamus in children and adolescents. PLOS ONE. 2019; 14 (8): e0221768. doi:10.1371/journal.pone.0221768  
314.   Saigusa Daisuke, Matsukawa Naomi, Tadaka Shu, et al. Metabolome Analysis of Human Plasma by GC-MS/MS in a Large-scale Cohort. Proteome Letters. 2019; 4 (1): 31-40. doi:10.14889/jpros.4.1_31  
315.   Nishi Daisuke, Su Kuan-Pin, Usuda Kentaro, et al. The Efficacy of Omega-3 Fatty Acids for Depressive Symptoms among Pregnant Women in Japan and Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial (SYNCHRO; NCT01948596). Psychotherapy and Psychosomatics. 2019; 88 (2): 122-124. doi:10.1159/000495296  
316.   Kobayashi Satomi, Yuan Xiaoyi, Sasaki Satoshi, et al. Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older. Public Health Nutrition. 2019; 22 (2): 212-222. doi:10.1017/S1368980018002331  
317.   Hattori Hiromitsu, Kitamura Akane, Takahashi Fumiaki, et al. The risk of secondary sex ratio imbalance and increased monozygotic twinning after blastocyst transfer: data from the Japan Environment and Children’s Study. Reproductive Biology and Endocrinology. 2019; 17 (1): 27. doi:10.1186/s12958-019-0471-1  
318.   Miura Emiri, Tsuchiya Naho, Igarashi Yu, et al. Respiratory resistance among adults in a population-based cohort study in Northern Japan. Respiratory Investigation. 2019; 57 (3): 274-281. doi:10.1016/j.resinv.2018.12.008  
319.   Uranbileg Baasanjav, Ito Nobuko, Kurano Makoto, et al. Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. Scientific Reports. 2019; 9 (1): 16578. doi:10.1038/s41598-019-52999-5  
320.   Sato Koji, Hirano Ikuo, Sekine Hiroki, et al. An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts. Scientific Reports. 2019; 9 (1): 11254. doi:10.1038/s41598-019-47766-5  
321.   Kanemitsu Yoshitomi, Mishima Eikan, Maekawa Masamitsu, et al. Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS. Scientific Reports. 2019; 9 (1): 19075. doi:10.1038/s41598-019-55600-1  
322.   Ikeda-Sakai Yasuko, Saito Yoshiyuki, Obara Taku, et al. Inadequate Folic Acid Intake Among Women Taking Antiepileptic Drugs During Pregnancy in Japan: A Cross-Sectional Study. Scientific Reports. 2019; 9 (1): 13497. doi:10.1038/s41598-019-49782-x  
323.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Mean diffusivity related to collectivism among university students in Japan. Scientific Reports. 2019; 9 (1): 1338. doi:10.1038/s41598-018-37995-5  
324.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Mean diffusivity related to rule-breaking guilt: the Macbeth effect in the sensorimotor regions. Scientific Reports. 2019; 9 (1): 12227. doi:10.1038/s41598-019-48654-8  
325.   Hitomi Yuki, Ueno Kazuko, Kawai Yosuke, et al. POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33. Scientific reports. 2019; 9 (1): 102. doi:10.1038/s41598-018-36490-1  
326.   Oe Yuji, Fushima Tomofumi, Sato Emiko, et al. Protease-activated receptor 2 protects against VEGF inhibitor-induced glomerular endothelial and podocyte injury. Scientific Reports. 2019; 9 (1): 2986. doi:10.1038/s41598-019-39914-8  
327.   Ishimaru Kazuhiro, Yoshioka Kazuaki, Kano Kuniyuki, et al. Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation. Scientific Reports. 2019; 9 (1): 18329. doi:10.1038/s41598-019-54877-6  
328.   Nishiyama Takeshi, Nakatochi Masahiro, Goto Atsushi, et al. Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population. Sleep. 2019; 42 (6): . doi:10.1093/sleep/zsz046  
329.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Mean diffusivity associated with trait emotional intelligence. Social Cognitive and Affective Neuroscience. 2019; 14 (8): 871-883. doi:10.1093/scan/nsz059  
330.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096  
331.   Dodo Mina, Kitamura Hiroshi, Shima Hiroki, et al. Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A. The Journal of Biochemistry. 2019; 165 (4): 323-334. doi:10.1093/jb/mvy108  
332.   Mimori Takahiro, Yasuda Jun, Kuroki Yoko, et al. Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing. The Pharmacogenomics Journal. 2019; 19 (2): 136-146. doi:10.1038/s41397-017-0010-4  
333.   Ishii Tadashi, Akaishi Tetsuya, Fujimori Kenji, et al. Application of Large Electronic Medical Database for Detecting Undiagnosed Patients in the General Population. The Tohoku Journal of Experimental Medicine. 2019; 249 (2): 113-119. doi:10.1620/tjem.249.113  
334.   Minegishi Naoko, Nishijima Ichiko, Nobukuni Takahiro, et al. Biobank Establishment and Sample Management in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2019; 248 (1): 45-55. doi:10.1620/tjem.248.45  
335.   Itto Rina, Oe Yuji, Imaruoka Kenta, et al. Glomerular Injury Is Exacerbated in Lupus-Prone MRL/lpr Mice Treated with a Protease-Activated Receptor 2 Antagonist. The Tohoku Journal of Experimental Medicine. 2019; 249 (2): 127-133. doi:10.1620/tjem.249.127  
336.   Sakama Reiko, Yokokawa Hirohide, Fujibayashi Kazutoshi, et al. Psychological Characteristics of Children at Two Years after the Great East Japan Earthquake: Analyses of Telephone Consultation Records. The Tohoku Journal of Experimental Medicine. 2019; 249 (2): 85-92. doi:10.1620/tjem.249.85  
337.   Narita Akira, Nakaya Naoki, Nakamura Tomohiro, et al. [Association between mild physical injury and psychological distress: Shichigahama Health Promotion Project]. [Nihon koshu eisei zasshi] Japanese journal of public health. 2018; 65 (4): 157-163. doi:10.11236/jph.65.4_157  
338.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. Allergology International. 2018; 67 (4): 481-486. doi:10.1016/j.alit.2018.02.009  
339.   Mishima Eikan, Fukuda Shinji, Kanemitsu Yoshitomi, et al. Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model. American Journal of Physiology-Renal Physiology. 2018; 315 (4): F824-F833. doi:10.1152/ajprenal.00314.2017  
340.   Sone Toshimasa, Nakaya Naoki, Tomata Yasutake, et al. Functional disability among partners and community activity in elderly Japanese: The Ohsaki Cohort 2006 Study. Archives of Gerontology and Geriatrics. 2018; 78 : 150-154. doi:10.1016/j.archger.2018.06.007  
341.   Siarot Lowela, Chutiwitoonchai Nopporn, Sato Hirotaka, et al. Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening. Biochemical and Biophysical Research Communications. 2018; 503 (4): 2970-2976. doi:10.1016/j.bbrc.2018.08.079  
342.   Watanabe Takashi, Saito Takahiro, Rico Evelyn Marie Gutiérrez, et al. Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation. Biochemical Pharmacology. 2018; 156 : 420-430. doi:10.1016/j.bcp.2018.09.010  
343.   Imai Yutaka, Asayama Kei, Fujiwara Seisuke, et al. Development and evaluation of a home nocturnal blood pressure monitoring system using a wrist-cuff device. Blood Pressure Monitoring. 2018; 23 (6): 318-326. doi:10.1097/MBP.0000000000000351  
344.   Yamada Kazunori D., Kinoshita Kengo. De novo profile generation based on sequence context specificity with the long short-term memory network. BMC Bioinformatics. 2018; 19 (1): 272. doi:10.1186/s12859-018-2284-1  
345.   Okamura Yasunobu, Kinoshita Kengo. Matataki: an ultrafast mRNA quantification method for large-scale reanalysis of RNA-Seq data. BMC Bioinformatics. 2018; 19 (1): 266. doi:10.1186/s12859-018-2279-y  
346.   Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0  
347.   Saito Sho, Ohi Takashi, Murakami Takahisa, et al. Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study. BMC Oral Health. 2018; 18 (1): 142. doi:10.1186/s12903-018-0602-7  
348.   Teraguchi Shunsuke, Kumagai Yutaro. Estimation of diffusion constants from single molecular measurement without explicit tracking. BMC Systems Biology. 2018; 12 (S1): 15. doi:10.1186/s12918-018-0526-5  
349.   Nakano Hironori, Ohira Tetsuya, Maeda Masaharu, et al. Associations of disaster-related and psychosocial factors with changes in smoking status after a disaster: a cross-sectional survey after the Great East Japan Earthquake. BMJ Open. 2018; 8 (6): e018943. doi:10.1136/bmjopen-2017-018943  
350.   Imai Yurika, Nagai Masato, Ohira Tetsuya, et al. Impact of social relationships on income–laughter relationships among older people: the JAGES cross-sectional study. BMJ Open. 2018; 8 (7): e019104. doi:10.1136/bmjopen-2017-019104  
351.   Ono Atsushi, Isojima Tsuyoshi, Yokoya Susumu, et al. Effect of the Fukushima earthquake on weight in early childhood: a retrospective analysis. BMJ Paediatrics Open. 2018; 2 (1): e000229. doi:10.1136/bmjpo-2017-000229  
352.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. General intelligence is associated with working memory-related brain activity: new evidence from a large sample study. Brain Structure and Function. 2018; 223 (9): 4243-4258. doi:10.1007/s00429-018-1747-5  
353.   Kono M, Akiyama M, Inoue Y, et al. Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children. British Journal of Dermatology. 2018; 179 (1): 190-191. doi:10.1111/bjd.16375  
354.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Association between serious psychological distress and nonparticipation in cancer screening and the modifying effect of socioeconomic status: Analysis of anonymized data from a national cross-sectional survey in Japan. Cancer. 2018; 124 (3): 555-562. doi:10.1002/cncr.31086  
355.   Tanikawa Chizu, Kamatani Yoichiro, Toyoshima Osamu, et al. Genome‐wide association study identifies gastric cancer susceptibility loci at 12q24.11‐12 and 20q11.21. Cancer Science. 2018; 109 (12): 4015-4024. doi:10.1111/cas.13815  
356.   Tanikawa Chizu, Kamatani Yoichiro, Takahashi Atsushi, et al. GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. Carcinogenesis. 2018; 39 (5): 652-660. doi:10.1093/carcin/bgy026  
357.   Kikuchi Haruhisa, Kawai Kosuke, Nakashiro Yota, et al. Construction of a Meroterpenoid‐Like Compounds Library Based on Diversity‐Enhanced Extracts. Chemistry – A European Journal. 2018; 25 (4): chem.201805417. doi:10.1002/chem.201805417  
358.   Hirata Takumi, Okamura Tomonori. Association Between Glycemic Control and Incident Stroke ― Overview From an Epidemiologic Study ―. Circulation Journal. 2018; 82 (6): 1499-1500. doi:10.1253/circj.CJ-18-0422  
359.   Satoh Michihiro, Murakami Takahisa, Asayama Kei, et al. N-Terminal Pro-B-Type Natriuretic Peptide Is Not a Significant Predictor of Stroke Incidence After 5 Years ― The Ohasama Study ―. Circulation Journal. 2018; 82 (8): 2055-2062. doi:10.1253/circj.CJ-17-1227  
360.   Okami Yukiko, Ueshima Hirotsugu, Nakamura Yasuyuki, et al. Time-Related Changes in Relationships Between the Keys Score, Dietary Lipids, and Serum Total Cholesterol in Japan ― NIPPON DATA80/90/2010 ―. Circulation Journal. 2018; 83 (1): 147-155. doi:10.1253/circj.CJ-18-0628  
361.   Doi A, Kano S, Asano M, et al. Autoantibodies to killer cell immunoglobulin‐like receptor 3DL1 in patients with systemic lupus erythematosus. Clinical & Experimental Immunology. 2018; 195 (3): cei.13235. doi:10.1111/cei.13235  
362.   Hosaka Miki, Inoue Ryusuke, Satoh Michihiro, et al. Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients. Clinical and Experimental Hypertension. 2018; 40 (5): 468-475. doi:10.1080/10641963.2017.1403617  
363.   Ogata Soshiro, Kamide Kei, Asayama Kei, et al. Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study. Clinical and Experimental Hypertension. 2018; 40 (4): 363-369. doi:10.1080/10641963.2017.1384481  
364.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Nocturnal blood pressure decline based on different time intervals and long-term cardiovascular risk: the Ohasama Study. Clinical and Experimental Hypertension. 2018; 40 (1): 1-7. doi:10.1080/10641963.2016.1259324  
365.   Kubota Wataru, Honda Masataka, Okada Hirokazu, et al. A consensus statement on health-care transition of patients with childhood-onset chronic kidney diseases: providing adequate medical care in adolescence and young adulthood. Clinical and Experimental Nephrology. 2018; 22 (4): 743-751. doi:10.1007/s10157-018-1589-8  
366.   Kabe Yasuaki, Suematsu Makoto, Sakamoto Satoshi, et al. Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera. Clinical Chemistry. 2018; 64 (10): 1463-1473. doi:10.1373/clinchem.2018.291963  
367.   Uranbileg Baasanjav, Nishikawa Takeshi, Ikeda Hitoshi, et al. Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer. Clinical Colorectal Cancer. 2018; 17 (2): e171-e182. doi:10.1016/j.clcc.2017.11.004  
368.   Hishinuma Eiji, Narita Yoko, Saito Sakae, et al. Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals. Drug Metabolism and Disposition. 2018; 46 (8): 1083-1090. doi:10.1124/dmd.118.081737  
369.   Tachikawa Masanori, Sumiyoshiya Yuna, Saigusa Daisuke, et al. Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus. Drug Metabolism and Disposition. 2018; 46 (5): 610-618. doi:10.1124/dmd.117.079244  
370.   Kumondai Masaki, Ito Akio, Hishinuma Eiji, et al. Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS). Drug Metabolism and Pharmacokinetics. 2018; 33 (6): 258-263. doi:10.1016/j.dmpk.2018.08.003  
371.   Saito Takahiro, Gutiérrez Rico Evelyn Marie, Kikuchi Aoi, et al. Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation. Drug Metabolism and Pharmacokinetics. 2018; 33 (6): 250-257. doi:10.1016/j.dmpk.2018.08.004  
372.   Kumondai Masaki, Hosono Hiroki, Maekawa Masamitsu, et al. Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C -oxidation and coumarin 7-hydroxylation. Drug Metabolism and Pharmacokinetics. 2018; 33 (1): 82-89. doi:10.1016/j.dmpk.2017.11.004  
373.   Okamoto Hiroshi, Taniyama Yusuke, Sakurai Tadashi, et al. Definitive chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-R) for advanced cervical esophageal cancer. Esophagus. 2018; 15 (4): 281-285. doi:10.1007/s10388-018-0627-7  
374.   Kogetsu Atsushi, Ogishima Soichi, Kato Kazuto. Authentication of Patients and Participants in Health Information Exchange and Consent for Medical Research: A Key Step for Privacy Protection, Respect for Autonomy, and Trustworthiness. Frontiers in Genetics. 2018; 9 : 167. doi:10.3389/fgene.2018.00167  
375.   Ogishima Soichi. [Human Genome Data and Drug Development]. Gan to kagaku ryoho. Cancer & chemotherapy. 2018; 45 (4): 597-600. http://www.ncbi.nlm.nih.gov/pubmed/29650811  
376.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. Is the eCura system useful for selecting patients who require radical surgery after noncurative endoscopic submucosal dissection for early gastric cancer? A comparative study. Gastric Cancer. 2018; 21 (3): 481-489. doi:10.1007/s10120-017-0769-7  
377.   Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588  
378.   Shibuya Yusuke, Tokunaga Hideki, Saito Sakae, et al. Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing. Genes, Chromosomes and Cancer. 2018; 57 (2): 51-60. doi:10.1002/gcc.22507  
379.   Hirata Satoshi, Kojima Kaname, Misawa Kazuharu, et al. Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population. Heliyon. 2018; 4 (5): e00625. doi:10.1016/j.heliyon.2018.e00625  
380.   Takeuchi Hikaru, Taki Yasuyuki, Asano Kohei, et al. Impact of frequency of internet use on development of brain structures and verbal intelligence: Longitudinal analyses. Human Brain Mapping. 2018; 39 (11): 4471-4479. doi:10.1002/hbm.24286  
381.   Yamaguchi-Kabata Yumi, Morihara Takashi, Ohara Tomoyuki, et al. Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer’s disease. Human Genetics. 2018; 137 (6-7): 521-533. doi:10.1007/s00439-018-1906-z  
382.   Shiga Yukihiro, Akiyama Masato, Nishiguchi Koji M, et al. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Human Molecular Genetics. 2018; 27 (8): 1486-1496. doi:10.1093/hmg/ddy053  
383.   Kubota Yoshimi, Higashiyama Aya, Sugiyama Daisuke, et al. Association between impairment of salty taste recognition and masked hypertension based on home blood pressure in Japanese residents: the KOBE study. Hypertension Research. 2018; 41 (9): 756-762. doi:10.1038/s41440-018-0074-9  
384.   Watabe Daisuke, Asayama Kei, Hanazawa Tomohiro, et al. Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study. Hypertension Research. 2018; 41 (8): 622-628. doi:10.1038/s41440-018-0050-4  
385.   Nochioka Kotaro. Urinary sodium excretion in acute heart failure: Interaction between heart and kidney. International Journal of Cardiology. 2018; 254 : 244-245. doi:10.1016/j.ijcard.2017.11.098  
386.   Nakaya Naoki, Nemoto Harumi, Yi Carine, et al. Effect of tsunami drill experience on evacuation behavior after the onset of the Great East Japan Earthquake. International Journal of Disaster Risk Reduction. 2018; 28 : 206-213. doi:10.1016/j.ijdrr.2018.02.037  
387.   Kato N, Isojima T, Yokoya S, et al. Earlier BMI rebound and lower pre-rebound BMI as risk of obesity among Japanese preschool children. International Journal of Obesity. 2018; 42 (1): 52-58. doi:10.1038/ijo.2017.242  
388.   Ohi T, Komiyama T, Miyoshi Y, et al. Maximum Occlusal Force and Incident Functional Disability in Older Adults: The Tsurugaya Project. JDR Clinical & Translational Research. 2018; 3 (2): 195-202. doi:10.1177/2380084418761329  
389.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Smoking among adults with serious psychological distress: Analysis of anonymized data from a national cross-sectional survey in Japan. Journal of Affective Disorders. 2018; 239 : 131-137. doi:10.1016/j.jad.2018.07.008  
390.   Kanaya Akihiro, Sato Toshihiro, Fuse Nobuo, et al. Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics. Journal of Anesthesia. 2018; 32 (2): 236-243. doi:10.1007/s00540-018-2470-3  
391.   Fujiyoshi Naoko, Arima Hisatomi, Satoh Atsushi, et al. Associations between Socioeconomic Status and the Prevalence and Treatment of Hypercholesterolemia in a General Japanese Population: NIPPON DATA2010. Journal of Atherosclerosis and Thrombosis. 2018; 25 (7): 606-620. doi:10.5551/jat.42531  
392.   Nakamura Yasuyuki, Narita Akira, Hachiya Tsuyoshi, et al. A Genome-wide Association Study in the Diabetic Patients Finds the 13q35 . 43-35 . 46 Locus Associated with Estimated Glomerular Filtration Rate : The Japan Multi-Institutional Collaborative Cohort Study. Journal of Clinical Diabetes. 2018; 2 (2): .  
393.   Goryoda Sayuri, Nishi Nobuo, Hozawa Atsushi, et al. Differences in Lifestyle Improvements With the Intention to Prevent Cardiovascular Diseases by Socioeconomic Status in a Representative Japanese Population: NIPPON DATA2010. Journal of Epidemiology. 2018; 28 (Supplement_III): S35-S39. doi:10.2188/jea.JE20170254  
394.   Imamura Haruhiko, Kogure Mana, Kita Yoshikuni, et al. Factors Related to Participation in Health Examinations for Japanese National Health Insurance: NIPPON DATA2010. Journal of Epidemiology. 2018; 28 (Supplement_III): S53-S58. doi:10.2188/jea.JE20170251  
395.   Yokomichi Hiroshi, Matsubara Hiroko, Ishikuro Mami, et al. Impact of the Great East Japan Earthquake on Body Mass Index, Weight, and Height of Infants and Toddlers: An Infant Survey. Journal of Epidemiology. 2018; 28 (5): 237-244. doi:10.2188/jea.JE20170006  
396.   Matsuyama Yusuke, Aida Jun, Tsuboya Toru, et al. Social Inequalities in Secondhand Smoke Among Japanese Non-smokers: A Cross-Sectional Study. Journal of Epidemiology. 2018; 28 (3): 133-139. doi:10.2188/jea.JE20160184  
397.   Kakuta Yoichi, Kawai Yosuke, Okamoto Daisuke, et al. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Journal of Gastroenterology. 2018; 53 (9): 1065-1078. doi:10.1007/s00535-018-1486-7  
398.   Naito Takeo, Yokoyama Naonobu, Kakuta Yoichi, et al. Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology. 2018; 33 (11): 1873-1881. doi:10.1111/jgh.14149  
399.   Yamamoto Kayono, Shimizu Atsushi, Aizawa Fumie, et al. A comparison of genome cohort participants’ genetic knowledge and preferences to receive genetic results before and after a genetics workshop. Journal of Human Genetics. 2018; 63 (11): 1139-1147. doi:10.1038/s10038-018-0494-z  
400.   Yamaguchi-Kabata Yumi, Yasuda Jun, Tanabe Osamu, et al. Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals. Journal of Human Genetics. 2018; 63 (2): 213-230. doi:10.1038/s10038-017-0347-1  
401.   Iwama Noriyuki, Metoki Hirohito, Nishigori Hidekazu, et al. Blood pressure changes during twin pregnancies. Journal of Hypertension. 2018; 37 (1): 1. doi:10.1097/HJH.0000000000001846  
402.   Doi Kent, Nishida Osamu, Shigematsu Takashi, et al. The Japanese Clinical Practice Guideline for acute kidney injury 2016. Journal of Intensive Care. 2018; 6 (1): 48. doi:10.1186/s40560-018-0308-6  
403.   Shido K., Kojima K., Yamasaki K., et al. 299 A genome-wide association study identifies a novel susceptibility locus for total IgE in a Japanese population from Tohoku Medical Megabank cohort study. Journal of Investigative Dermatology. 2018; 138 (5): S51. doi:10.1016/j.jid.2018.03.305  
404.   Tanaka Yukari, Kanazawa Motoyori, Palsson Olafur S, et al. Increased Postprandial Colonic Motility and Autonomic Nervous System Activity in Patients With Irritable Bowel Syndrome: A Prospective Study. Journal of Neurogastroenterology and Motility. 2018; 24 (1): 87-95. doi:10.5056/jnm16216  
405.   Ohta Tazro, Kawashima Takeshi, Shinozaki Natsuko O, et al. Collaborative environmental DNA sampling from petal surfaces of flowering cherry Cerasus × yedoensis ‘Somei-yoshino’ across the Japanese archipelago. Journal of Plant Research. 2018; 131 (4): 709-717. doi:10.1007/s10265-018-1017-x  
406.   Komiyama Takamasa, Ohi Takashi, Miyoshi Yoshitada, et al. Relationship between status of dentition and incident functional disability in an elderly Japanese population: prospective cohort study of the Tsurugaya project. Journal of Prosthodontic Research. 2018; 62 (4): 443-448. doi:10.1016/j.jpor.2018.04.003  
407.   Ohseto Hisashi, Ishikuro Mami, Kikuya Masahiro, et al. Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study. Journal of Psychosomatic Research. 2018; 107 : 20-25. doi:10.1016/j.jpsychores.2018.01.013  
408.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Association Between Amplitude of Seasonal Variation in Self‐Measured Home Blood Pressure and Cardiovascular Outcomes: HOMED‐BP (Hypertension Objective Treatment Based on Measurement By Electrical Devices of Blood Pressure) Study. Journal of the American Heart Association. 2018; 7 (10): . doi:10.1161/JAHA.117.008509  
409.   Jia Xiaoyuan, Horinouchi Tomoko, Hitomi Yuki, et al. Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population. Journal of the American Society of Nephrology. 2018; 29 (8): 2189-2199. doi:10.1681/ASN.2017080859  
410.   Suzuki Norio, Matsuo-Tezuka Yukari, Sasaki Yusuke, et al. Iron attenuates erythropoietin production by decreasing hypoxia-inducible transcription factor 2α concentrations in renal interstitial fibroblasts. Kidney International. 2018; 94 (5): 900-911. doi:10.1016/j.kint.2018.06.028  
411.   Thyreau Benjamin, Sato Kazunori, Fukuda Hiroshi, Taki Yasuyuki. Segmentation of the hippocampus by transferring algorithmic knowledge for large cohort processing. Medical Image Analysis. 2018; 43 : 214-228. doi:10.1016/j.media.2017.11.004  
412.   Sekine Hiroki, Okazaki Keito, Kato Koichiro, et al. O -GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1. Molecular and Cellular Biology. 2018; 38 (17): . doi:10.1128/MCB.00252-18  
413.   Zhang Xuewei, Kitatani Kazuyuki, Toyoshima Masafumi, et al. Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer. Molecular Cancer Therapeutics. 2018; 17 (1): 50-59. doi:10.1158/1535-7163.MCT-17-0173  
414.   Yuan Xunmei, Tsujimoto Kazutaka, Hashimoto Koshi, et al. Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood. Nature Communications. 2018; 9 (1): 636. doi:10.1038/s41467-018-03038-w  
415.   Takeuchi Fumihiko, Akiyama Masato, Matoba Nana, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications. 2018; 9 (1): 5052. doi:10.1038/s41467-018-07345-0  
416.   Ashraf Shazia, Kudo Hiroki, Rao Jia, et al. Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. Nature Communications. 2018; 9 (1): 1960. doi:10.1038/s41467-018-04193-w  
417.   Maruyama Tsukasa, Takeuchi Hikaru, Taki Yasuyuki, et al. Effects of Time-Compressed Speech Training on Multiple Functional and Structural Neural Mechanisms Involving the Left Superior Temporal Gyrus. Neural Plasticity. 2018; 2018 : 1-12. doi:10.1155/2018/6574178  
418.   Rashad Sherif, Niizuma Kuniyasu, Saigusa Daisuke, et al. Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia. Neuroscience. 2018; 384 : 188-202. doi:10.1016/j.neuroscience.2018.05.015  
419.   Tadaka Shu, Saigusa Daisuke, Motoike Ikuko N., et al. jMorp: Japanese Multi Omics Reference Panel. Nucleic Acids Research. 2018; 46 (D1): D551-D557. doi:10.1093/nar/gkx978  
420.   Hasegawa-Minato Junko, Toyoshima Masafumi, Ishibashi Masumi, et al. Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers. Oncotarget. 2018; 9 (3): 3483-3496. doi:10.18632/oncotarget.23322  
421.   Saito Takahiro, Kikuchi Aoi, Kaneko Akira, et al. Rapid and sensitive multiplex single-tube nested PCR for the identification of five human Plasmodium species. Parasitology International. 2018; 67 (3): 277-283. doi:10.1016/j.parint.2018.01.005  
422.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Antihypertensives prescribed for pregnant women in Japan: Prevalence and timing determined from a database of health insurance claims. Pharmacoepidemiology and Drug Safety. 2018; 27 (12): 1325-1334. doi:10.1002/pds.4654  
423.   Ishikawa Tomofumi, Obara Taku, Nishigori Hidekazu, et al. Development of algorithms to determine the onset of pregnancy and delivery date using health care administrative data in a university hospital in Japan. Pharmacoepidemiology and Drug Safety. 2018; 27 (7): 751-762. doi:10.1002/pds.4444  
424.   Obayashi Takeshi, Aoki Yuichi, Tadaka Shu, et al. ATTED-II in 2018: A Plant Coexpression Database Based on Investigation of the Statistical Property of the Mutual Rank Index. Plant and Cell Physiology. 2018; 59 (1): e3-e3. doi:10.1093/pcp/pcx191  
425.   Chiba Hirofumi, Kakuta Yoichi, Kinouchi Yoshitaka, et al. Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease. PLOS ONE. 2018; 13 (3): e0194036. doi:10.1371/journal.pone.0194036  
426.   Yodsurang Varalee, Tang Yaqi, Takahashi Yukie, et al. Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1. PLOS ONE. 2018; 13 (12): e0209096. doi:10.1371/journal.pone.0209096  
427.   Sugawara Junichi, Iwama Noriyuki, Hoshiai Tetsuro, et al. Regional Birth Outcomes after the 2011 Great East Japan Earthquake and Tsunami in Miyagi Prefecture. Prehospital and Disaster Medicine. 2018; 33 (2): 215-219. doi:10.1017/S1049023X18000183  
428.   Nishioka Masaki, Bundo Miki, Ueda Junko, et al. Identification of somatic mutations in postmortem human brains by whole genome sequencing and their implications for psychiatric disorders. Psychiatry and Clinical Neurosciences. 2018; 72 (4): 280-294. doi:10.1111/pcn.12632  
429.   Sakai Mai, Takeuchi Hikaru, Yu Zhiqian, et al. Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain. Psychiatry and Clinical Neurosciences. 2018; 72 (6): 409-422. doi:10.1111/pcn.12649  
430.   Kuroha Takeshi, Nagai Keisuke, Gamuyao Rico, et al. Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding. Science. 2018; 361 (6398): 181-186. doi:10.1126/science.aat1577  
431.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Allergic tendencies are associated with larger gray matter volumes. Scientific Reports. 2018; 8 (1): 3694. doi:10.1038/s41598-018-21985-8  
432.   Hiyama Gen, Mizushima Shusei, Matsuzaki Mei, et al. Female Japanese quail visually differentiate testosterone-dependent male attractiveness for mating preferences. Scientific Reports. 2018; 8 (1): 10012. doi:10.1038/s41598-018-28368-z  
433.   Hachiya Tsuyoshi, Narita Akira, Ohmomo Hideki, et al. Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus. Scientific Reports. 2018; 8 (1): 14162. doi:10.1038/s41598-018-32074-1  
434.   Oe Yuji, Ko Mieko, Fushima Tomofumi, et al. Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase. Scientific Reports. 2018; 8 (1): 102. doi:10.1038/s41598-017-18260-7  
435.   Latt Khun Zaw, Honda Kenjiro, Thiri Myo, et al. Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy. Scientific Reports. 2018; 8 (1): 15576. doi:10.1038/s41598-018-33612-7  
436.   Sato Kota, Saigusa Daisuke, Saito Ritsumi, et al. Metabolomic changes in the mouse retina after optic nerve injury. Scientific Reports. 2018; 8 (1): 11930. doi:10.1038/s41598-018-30464-z  
437.   Nishida Nao, Aiba Yoshihiro, Hitomi Yuki, et al. NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population. Scientific Reports. 2018; 8 (1): 8071. doi:10.1038/s41598-018-26369-6  
438.   Obara Taku, Ishikuro Mami, Tamiya Gen, et al. Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports. 2018; 8 (1): 14840. doi:10.1038/s41598-018-33110-w  
439.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Refractive error is associated with intracranial volume. Scientific Reports. 2018; 8 (1): 175. doi:10.1038/s41598-017-18669-0  
440.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Shorter sleep duration and better sleep quality are associated with greater tissue density in the brain. Scientific Reports. 2018; 8 (1): 5833. doi:10.1038/s41598-018-24226-0  
441.   Ishibashi Masumi, Toyoshima Masafumi, Zhang Xuewei, et al. Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer. Scientific Reports. 2018; 8 (1): 13207. doi:10.1038/s41598-018-31069-2  
442.   Koyama Shihoko, Aida Jun, Cable Noriko, et al. Sleep duration and remaining teeth among older people. Sleep Medicine. 2018; 52 : 18-22. doi:10.1016/j.sleep.2018.07.020  
443.   Sato Yukihiro, Aida Jun, Tsuboya Toru, et al. Generalized and particularized trust for health between urban and rural residents in Japan: A cohort study from the JAGES project. Social Science & Medicine. 2018; 202 : 43-53. doi:10.1016/j.socscimed.2018.02.015  
444.   Ito Hirotaka, Gotoda Takuji, Oyama Tsuneo, et al. Long-term oncological outcomes of submucosal manipulation during non-curative endoscopic submucosal dissection for submucosal invasive gastric cancer: a multicenter retrospective study in Japan. Surgical Endoscopy. 2018; 32 (1): 196-203. doi:10.1007/s00464-017-5659-x  
445.   Kondo Hiroko X., Yoshida Norio, Shirota Matsuyuki, Kinoshita Kengo. Molecular Mechanism of Depolarization-Dependent Inactivation in W366F Mutant of Kv1.2. The Journal of Physical Chemistry B. 2018; 122 (48): 10825-10833. doi:10.1021/acs.jpcb.8b09446  
446.   Iwaki Masayo, Takeshita Kohei, Kondo Hiroko X., et al. Zn 2+ -Binding to the Voltage-Gated Proton Channel Hv1/VSOP. The Journal of Physical Chemistry B. 2018; 122 (39): 9076-9080. doi:10.1021/acs.jpcb.8b04890  
447.   Inagaki Masatoshi, Fujiwara Masaki, Nakaya Naoki, et al. Low Cancer Screening Rates among Japanese People with Schizophrenia: A Cross-Sectional Study. The Tohoku Journal of Experimental Medicine. 2018; 244 (3): 209-218. doi:10.1620/tjem.244.209  
448.   Ishikuro Mami, Obara Taku, Osanai Tamae, et al. Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2018; 246 (2): 97-105. doi:10.1620/tjem.246.97  
449.   Takahashi Nobuyuki, Li Feng, Fushima Tomofumi, et al. Vitamin B3 Nicotinamide: A Promising Candidate for Treating Preeclampsia and Improving Fetal Growth. The Tohoku Journal of Experimental Medicine. 2018; 244 (3): 243-248. doi:10.1620/tjem.244.243  
450.   Kumada Kazuki, Yasuda Jun. Evolutionary acquired robustness and vulnerability in cancer genome: negligible negative selection in carcinogenesis. Translational Cancer Research. 2018; 7 (S4): S445-S448. doi:10.21037/tcr.2018.02.15  
451.   山本 雅之, 勝岡 史城. 東北メディカル・メガバンク計画が実施するゲノムコホート研究. 医学のあゆみ. 2018; 266 ((5)): 370-376.  
452.   長﨑 正朗. 日本人ゲノムシークエンスと多様性──世界のヒトゲノム情報基盤構築の現状と日本人ヒトゲノム情報基盤構築の意義. 医学のあゆみ. 2018; 266 ((6)): 357-363.  
453.   成田 暁, 中谷 直樹, 中村 智洋, et al. 東日本大震災における軽度身体的外傷と心理的苦痛の関連:七ヶ浜健康増進プロジェクト. 日本公衆衛生雑誌. 2018; 65 (4): 157-163. https://www.jstage.jst.go.jp/article/jph/65/4/65_17-075/_article/-char/ja/  
454.   Sasaki Yuri, Aida Jun, Tsuji Taishi, et al. Does the Type of Residential Housing Matter for Depressive Symptoms in the Aftermath of a Disaster? Insights from the Great East Japan Earthquake and Tsunami. American Journal of Epidemiology. 2017; 187 (3): 455-464. doi:10.1093/aje/kwx274  
455.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. A Scoring System to Stratify Curability after Endoscopic Submucosal Dissection for Early Gastric Cancer: “eCura system”. American Journal of Gastroenterology. 2017; 112 (6): 874-881. doi:10.1038/ajg.2017.95  
456.   Nezu Masahiro, Suzuki Norio, Yamamoto Masayuki. Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression. American Journal of Nephrology. 2017; 45 (6): 473-483. doi:10.1159/000475890  
457.   Nakayama Akiyoshi, Nakaoka Hirofumi, Yamamoto Ken, et al. GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Annals of the Rheumatic Diseases. 2017; 76 (5): 869-877. doi:10.1136/annrheumdis-2016-209632  
458.   Miyashita Takenori, Inamoto Ryuhei, Fukuda Shinjiro, et al. Hormonal changes following a low-salt diet in patients with Ménière's disease. Auris Nasus Larynx. 2017; 44 (1): 52-57. doi:10.1016/j.anl.2016.03.001  
459.   Hishinuma Eiji, Akai Fumika, Narita Yoko, et al. Functional characterization of 21 allelic variants of dihydropyrimidinase. Biochemical Pharmacology. 2017; 143 : 118-128. doi:10.1016/j.bcp.2017.06.121  
460.   Takayanagi Yuki, Yoshida Masahide, Takashima Akihide, et al. Activation of Supraoptic Oxytocin Neurons by Secretin Facilitates Social Recognition. Biological Psychiatry. 2017; 81 (3): 243-251. doi:10.1016/j.biopsych.2015.11.021  
461.   Katayama Saori, Suzuki Mikiko, Yamaoka Ayaka, et al. GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. Blood. 2017; 130 (7): 908-919. doi:10.1182/blood-2016-12-756767  
462.   Lee Mary P., Tanabe Osamu, Shi Lihong, et al. The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation. Blood. 2017; 130 (23): 2537-2547. doi:10.1182/blood-2017-05-783159  
463.   Yasunaga Mayu, Fujita Yasuko, Saito Rumiko, et al. Continuous long-term cytotoxicity monitoring in 3D spheroids of beetle luciferase-expressing hepatocytes by nondestructive bioluminescence measurement. BMC Biotechnology. 2017; 17 (1): 54. doi:10.1186/s12896-017-0374-1  
464.   Takai-Igarashi Takako, Kinoshita Kengo, Nagasaki Masao, et al. Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design. BMC Medical Informatics and Decision Making. 2017; 17 (1): 100. doi:10.1186/s12911-017-0494-5  
465.   Ishikuro Mami, Matsubara Hiroko, Kikuya Masahiro, et al. Disease prevalence among nursery school children after the Great East Japan earthquake. BMJ Global Health. 2017; 2 (2): e000127. doi:10.1136/bmjgh-2016-000127  
466.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Lenticular nucleus correlates of general self-efficacy in young adults. Brain Structure and Function. 2017; 222 (7): 3309-3318. doi:10.1007/s00429-017-1406-2  
467.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Mean diffusivity of basal ganglia and thalamus specifically associated with motivational states among mood states. Brain Structure and Function. 2017; 222 (2): 1027-1037. doi:10.1007/s00429-016-1262-5  
468.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. The anterior midcingulate cortex as a neural node underlying hostility in young adults. Brain Structure and Function. 2017; 222 (1): 61-70. doi:10.1007/s00429-016-1200-6  
469.   Yu Zhiqian, Fukushima Hotaka, Ono Chiaki, et al. Microglial production of TNF-alpha is a key element of sustained fear memory. Brain, Behavior, and Immunity. 2017; 59 : 313-321. doi:10.1016/j.bbi.2016.08.011  
470.   Pan Xiaoqing, Nariai Naoki, Fukuhara Noriko, et al. Monitoring of minimal residual disease in early T‐cell precursor acute lymphoblastic leukaemia by next‐generation sequencing. British Journal of Haematology. 2017; 176 (2): 318-321. doi:10.1111/bjh.13948  
471.   Nagai Masato, Murakami Yoshitaka, Tamakoshi Akiko, et al. Fasting but not casual blood glucose is associated with pancreatic cancer mortality in Japanese: EPOCH-JAPAN. Cancer Causes & Control. 2017; 28 (6): 625-633. doi:10.1007/s10552-017-0884-0  
472.   Bowman John L., Kohchi Takayuki, Yamato Katsuyuki T., et al. Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome. Cell. 2017; 171 (2): 287-304.e15. doi:10.1016/j.cell.2017.09.030  
473.   Yagishita Yoko, Uruno Akira, Fukutomi Toshiaki, et al. Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress. Cell Reports. 2017; 18 (8): 2030-2044. doi:10.1016/j.celrep.2017.01.064  
474.   Tsugita Misato, Morimoto Nobuyuki, Tashiro Manabu, et al. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Reports. 2017; 18 (5): 1298-1311. doi:10.1016/j.celrep.2017.01.004  
475.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Selective serotonin reuptake inhibitors and risk of major congenital anomalies for pregnancies in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study. Congenital Anomalies. 2017; 57 (3): 72-78. doi:10.1111/cga.12202  
476.   Hatta Waku, Koike Tomoyuki, Iijima Katsunori, et al. The Risk Factors for Metastasis in Non-Ampullary Duodenal Neuroendocrine Tumors Measuring 20 mm or Less in Diameter. Digestion. 2017; 95 (3): 201-209. doi:10.1159/000459619  
477.   Sakurai Kasumi, Nishigori Hidekazu, Nishigori Toshie, et al. Incidence of Domestic Violence Against Pregnant Females After the Great East Japan Earthquake in Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (2): 216-226. doi:10.1017/dmp.2016.109  
478.   Nishigori Hidekazu, Nishigori Toshie, Sakurai Kasumi, et al. Pregnant Women’s Awareness of Social Capital in the Great East Japan Earthquake-Affected Areas of Miyagi Prefecture: The Japan Environment and Children’s Study. Disaster Medicine and Public Health Preparedness. 2017; 11 (3): 355-364. doi:10.1017/dmp.2016.150  
479.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Psychological Distress and the Risk of Withdrawing From Hypertension Treatment After an Earthquake Disaster. Disaster Medicine and Public Health Preparedness. 2017; 11 (2): 179-182. doi:10.1017/dmp.2016.102  
480.   Matsuhashi Tetsuro, Sato Takeya, Kanno Shin-ichiro, et al. Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases. EBioMedicine. 2017; 20 : 27-38. doi:10.1016/j.ebiom.2017.05.016  
481.   Sakai Taichi, Sugawara Yumi, Watanabe Ikue, et al. Age at first birth and long-term mortality for mothers: the Ohsaki cohort study. Environmental Health and Preventive Medicine. 2017; 22 (1): 24. doi:10.1186/s12199-017-0631-x  
482.   Hidaka Hiroshi, Ozawa Daiki, Kuriyama Shinichi, et al. Risk factors for delayed oral dietary intake in patients with deep neck infections including descending necrotizing mediastinitis. European Archives of Oto-Rhino-Laryngology. 2017; 274 (11): 3951-3958. doi:10.1007/s00405-017-4716-3  
483.   Igarashi Yuko, Obara Taku, Ishikuro Mami, et al. Randomized controlled trial of the effects of consumption of ‘Yabukita’ or ‘Benifuuki’ encapsulated tea-powder on low-density lipoprotein cholesterol level and body weight. Food & Nutrition Research. 2017; 61 (1): 1334484. doi:10.1080/16546628.2017.1334484  
484.   Tsuchida Kouhei, Tsujita Tadayuki, Hayashi Makiko, et al. Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation. Free Radical Biology and Medicine. 2017; 103 : 236-247. doi:10.1016/j.freeradbiomed.2016.12.041  
485.   Ikeda Shigeyuki, Takeuchi Hikaru, Taki Yasuyuki, et al. A Comprehensive Analysis of the Correlations between Resting-State Oscillations in Multiple-Frequency Bands and Big Five Traits. Frontiers in Human Neuroscience. 2017; 11 (14): 2146-2160. doi:10.3389/fnhum.2017.00321  
486.   Motomura Yuki, Kitamura Shingo, Nakazaki Kyoko, et al. Recovery from Unrecognized Sleep Loss Accumulated in Daily Life Improved Mood Regulation via Prefrontal Suppression of Amygdala Activity. Frontiers in Neurology. 2017; 8 : . doi:10.3389/fneur.2017.00306  
487.   Hasegawa Atsushi, Shimizu Ritsuko. GATA1 Activity Governed by Configurations of cis-Acting Elements. Frontiers in Oncology. 2017; 6 : . doi:10.3389/fonc.2016.00269  
488.   Matsuura Kentaro, Sawai Hiromi, Ikeo Kazuho, et al. Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. Gastroenterology. 2017; 152 (6): 1383-1394. doi:10.1053/j.gastro.2017.01.041  
489.   Kaneko Hiroshi, Katoh Takehide, Hirano Ikuo, et al. Induction of erythropoietin gene expression in epithelial cells by chemicals identified in GATA inhibitor screenings. Genes to Cells. 2017; 22 (11): 939-952. doi:10.1111/gtc.12537  
490.   Ueki Masao, Kawasaki Yoshinori, Tamiya Gen. Detecting genetic association through shortest paths in a bidirected graph. Genetic Epidemiology. 2017; 41 (6): 481-497. doi:10.1002/gepi.22051  
491.   Tomata Yasutake, Sugiyama Kemmyo, Kaiho Yu, et al. Predictive ability of a simple subjective memory complaints scale for incident dementia: Evaluation of Japan's national checklist, the “Kihon Checklist”. Geriatrics & Gerontology International. 2017; 17 (9): 1300-1305. doi:10.1111/ggi.12864  
492.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Creative females have larger white matter structures: Evidence from a large sample study. Human Brain Mapping. 2017; 38 (1): 414-430. doi:10.1002/hbm.23369  
493.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. The VEGF gene polymorphism impacts brain volume and arterial blood volume. Human Brain Mapping. 2017; 38 (7): 3516-3526. doi:10.1002/hbm.23606  
494.   Kawashima Minae, Hitomi Yuki, Aiba Yoshihiro, et al. Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population. Human Molecular Genetics. 2017; 26 (3): ddw406. doi:10.1093/hmg/ddw406  
495.   Juhanoja Eeva P., Niiranen Teemu J., Johansson Jouni K., et al. Outcome-Driven Thresholds for Increased Home Blood Pressure Variability. Hypertension. 2017; 69 (4): 599-607. doi:10.1161/HYPERTENSIONAHA.116.08603  
496.   Metoki Hirohito, Iwama Noriyuki, Ishikuro Mami, et al. Monitoring and evaluation of out-of-office blood pressure during pregnancy. Hypertension Research. 2017; 40 (2): 107-109. doi:10.1038/hr.2016.112  
497.   Hanazawa Tomohiro, Asayama Kei, Watabe Daisuke, et al. Seasonal variation in self-measured home blood pressure among patients on antihypertensive medications: HOMED-BP study. Hypertension Research. 2017; 40 (3): 284-290. doi:10.1038/hr.2016.133  
498.   Zheng W, Yokomichi H, Matsubara H, et al. Longitudinal changes in body mass index of children affected by the Great East Japan Earthquake. International Journal of Obesity. 2017; 41 (4): 606-612. doi:10.1038/ijo.2017.6  
499.   Hamanaka Teruhiko, Kimura Masae, Sakurai Tetsuro, et al. A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients. Investigative Opthalmology & Visual Science. 2017; 58 (5): 2818. doi:10.1167/iovs.16-20646  
500.   Oba Akira, Nakaya Naoki, Saito-Nakaya Kumi, et al. Psychological distress in men with prostate cancer and their partners before and after cancer diagnosis: a longitudinal study. Japanese Journal of Clinical Oncology. 2017; 47 (8): 735-742. doi:10.1093/jjco/hyx066  
501.   Hotta Kinichi, Matsuda Takahisa, Kakugawa Yasuo, et al. Regional colorectal cancer screening program using colonoscopy on an island: a prospective Nii-jima study. Japanese Journal of Clinical Oncology. 2017; 47 (2): 118-122. doi:10.1093/jjco/hyw155  
502.   Liu Ta-Chiang, Naito Takeo, Liu Zhenqiu, et al. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn’s disease patients. JCI Insight. 2017; 2 (6): e91917. doi:10.1172/jci.insight.91917  
503.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Risk Factors for Stroke among Young-Old and Old-Old Community-Dwelling Adults in Japan: The Ohasama Study. Journal of Atherosclerosis and Thrombosis. 2017; 24 (3): 290-300. doi:10.5551/jat.35766  
504.   Kanemitsu Yoshitomi, Asaji Kei, Matsumoto Yotaro, et al. Simultaneous quantitative analysis of uremic toxins by LC–MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column. Journal of Chromatography B. 2017; 1068-1069 : 1-8. doi:10.1016/j.jchromb.2017.10.009  
505.   Kumagai Chihiro, Sato Yukuto, Yamashita Riu, et al. Semi-automated quantitative analysis of the human skin microbiome diversity. Journal of Dermatological Science. 2017; 86 (2): e75. doi:10.1016/j.jdermsci.2017.02.219  
506.   Kikuya Masahiro, Matsubara Hiroko, Ishikuro Mami, et al. Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey. Journal of Epidemiology. 2017; 27 (10): 462-468. doi:10.1016/j.je.2016.09.012  
507.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the health examination survey on early childhood physical growth in the Great East Japan Earthquake affected areas. Journal of Epidemiology. 2017; 27 (3): 135-142. doi:10.1016/j.je.2016.03.001  
508.   Hatta Waku, Gotoda Takuji, Oyama Tsuneo, et al. Is radical surgery necessary in all patients who do not meet the curative criteria for endoscopic submucosal dissection in early gastric cancer? A multi-center retrospective study in Japan. Journal of Gastroenterology. 2017; 52 (2): 175-184. doi:10.1007/s00535-016-1210-4  
509.   Ueta Mayumi, Sawai Hiromi, Shingaki Ryosei, et al. Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens–Johnson syndrome with severe ocular complications. Journal of Human Genetics. 2017; 62 (4): 485-489. doi:10.1038/jhg.2016.160  
510.   Yamamoto Kayono, Hachiya Tsuyoshi, Fukushima Akimune, et al. Population-based biobank participants’ preferences for receiving genetic test results. Journal of Human Genetics. 2017; 62 (12): 1037-1048. doi:10.1038/jhg.2017.81  
511.   Asayama Kei, Hozawa Atsushi, Taguri Masataka, et al. Blood pressure, heart rate, and double product in a pooled cohort. Journal of Hypertension. 2017; 35 (9): 1808-1815. doi:10.1097/HJH.0000000000001399  
512.   Murakami Keiko, Asayama Kei, Satoh Michihiro, et al. Home blood pressure predicts stroke incidence among older adults with impaired physical function. Journal of Hypertension. 2017; 35 (12): 2395-2401. doi:10.1097/HJH.0000000000001473  
513.   Shido K., Kojima K., Hozawa A., et al. 503 Genome-wide association study identifies novel susceptibility loci for tanning ability in Japanese population. Journal of Investigative Dermatology. 2017; 137 (5): S86. doi:10.1016/j.jid.2017.02.523  
514.   Tsubota-Utsugi Megumi, Satoh Michihiro, Tomita Naoki, et al. Lacunar Infarcts Rather than White Matter Hyperintensity as a Predictor of Future Higher Level Functional Decline: The Ohasama Study. Journal of Stroke and Cerebrovascular Diseases. 2017; 26 (2): 376-384. doi:10.1016/j.jstrokecerebrovasdis.2016.09.036  
515.   Yokoro Miyuki, Nakayama Yosuke, Yamagishi Sho-ichi, et al. Asymmetric Dimethylarginine Contributes to the Impaired Response to Erythropoietin in CKD-Anemia. Journal of the American Society of Nephrology. 2017; 28 (9): 2670-2680. doi:10.1681/ASN.2016111184  
516.   Kikuya Masahiro. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. JPCD. 2017; 4 : 1-4. doi:10.17303/jpcd.2017.4.101  
517.   Mishima Eikan, Fukuda Shinji, Mukawa Chikahisa, et al. Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS–based metabolomics approach. Kidney International. 2017; 92 (3): 634-645. doi:10.1016/j.kint.2017.02.011  
518.   Nezu Masahiro, Souma Tomokazu, Yu Lei, et al. Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. Kidney International. 2017; 91 (2): 387-401. doi:10.1016/j.kint.2016.08.023  
519.   Tatewaki Yasuko, Mutoh Tatsushi, Thyreau Benjamin, et al. Phase Difference-Enhanced Magnetic Resonance (MR) Imaging (PADRE) Technique for the Detection of Age-Related Microstructural Changes in Optic Radiation: Comparison with Diffusion Tensor Imaging (DTI). Medical Science Monitor. 2017; 23 : 5495-5503. doi:10.12659/MSM.905571  
520.   Baird Liam, Tsujita Tadayuki, Kobayashi Eri H, et al. A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways. Molecular and Cellular Biology. 2017; 37 (4): . doi:10.1128/MCB.00439-16  
521.   Yu Lei, Takai Jun, Otsuki Akihito, et al. Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis. Molecular and Cellular Biology. 2017; 37 (8): MCB.00592-16. doi:10.1128/MCB.00592-16  
522.   Yu Lei, Moriguchi Takashi, Kaneko Hiroshi, et al. Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury. Molecular and Cellular Biology. 2017; 37 (22): e00211-17. doi:10.1128/MCB.00211-17  
523.   Hirano Ikuo, Suzuki Norio, Yamazaki Shun, et al. Renal Anemia Model Mouse Established by Transgenic Rescue with an Erythropoietin Gene Lacking Kidney-Specific Regulatory Elements. Molecular and Cellular Biology. 2017; 37 (4): MCB.00451-16. doi:10.1128/MCB.00451-16  
524.   Ishida Noriko, Nakagawa Tadashi, Iemura Shun-Ichiro, et al. Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair. Molecular and Cellular Biology. 2017; 37 (4): . doi:10.1128/MCB.00347-16  
525.   Ushio Masayuki, Fukuda Hisato, Inoue Toshiki, et al. Environmental DNA enables detection of terrestrial mammals from forest pond water. Molecular Ecology Resources. 2017; 17 (6): e63-e75. doi:10.1111/1755-0998.12690  
526.   Suzuki Takafumi, Seki Shiori, Hiramoto Keiichiro, et al. Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus. Nature Communications. 2017; 8 (1): 14577. doi:10.1038/ncomms14577  
527.   Fukushima Kenji, Fang Xiaodong, Alvarez-Ponce David, et al. Genome of the pitcher plant Cephalotus reveals genetic changes associated with carnivory. Nature Ecology & Evolution. 2017; 1 (3): 0059. doi:10.1038/s41559-016-0059  
528.   Akiyama Masato, Okada Yukinori, Kanai Masahiro, et al. Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. Nature Genetics. 2017; 49 (10): 1458-1467. doi:10.1038/ng.3951  
529.   Low Siew-Kee, Takahashi Atsushi, Ebana Yusuke, et al. Identification of six new genetic loci associated with atrial fibrillation in the Japanese population. Nature Genetics. 2017; 49 (6): 953-958. doi:10.1038/ng.3842  
530.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Regional homogeneity, resting-state functional connectivity and amplitude of low frequency fluctuation associated with creativity measured by divergent thinking in a sex-specific manner. NeuroImage. 2017; 152 : 258-269. doi:10.1016/j.neuroimage.2017.02.079  
531.   Hachiya Tsuyoshi, Furukawa Ryohei, Shiwa Yuh, et al. Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies. npj Genomic Medicine. 2017; 2 (1): 11. doi:10.1038/s41525-017-0016-5  
532.   Köhler Sebastian, Vasilevsky Nicole A, Engelstad Mark, et al. The Human Phenotype Ontology in 2017. Nucleic Acids Research. 2017; 45 (D1): D865-D876. doi:10.1093/nar/gkw1039  
533.   Wada M, Canals D, Adada M, et al. P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment. Oncogene. 2017; 36 (47): 6649-6657. doi:10.1038/onc.2017.274  
534.   Isojima Tsuyoshi, Yokoya Susumu, Ono Atsushi, et al. Prolonged elevated body mass index in preschool children after the Great East Japan Earthquake. Pediatrics International. 2017; 59 (9): 1002-1009. doi:10.1111/ped.13340  
535.   Nishigori Hidekazu, Obara Taku, Nishigori Toshie, et al. Drug Use before and during Pregnancy in Japan: The Japan Environment and Children’s Study. Pharmacy. 2017; 5 (4): 21. doi:10.3390/pharmacy5020021  
536.   Shiga Yukihiro, Nishiguchi Koji M., Kawai Yosuke, et al. Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7. PLOS ONE. 2017; 12 (12): e0186678. doi:10.1371/journal.pone.0186678  
537.   Sato Takahiro, Sugawara Junichi, Aizawa Naoko, et al. Longitudinal changes of ocular blood flow using laser speckle flowgraphy during normal pregnancy. PLOS ONE. 2017; 12 (3): e0173127. doi:10.1371/journal.pone.0173127  
538.   Takeuchi Fumihiko, Katsuya Tomohiro, Kimura Ryosuke, et al. The fine-scale genetic structure and evolution of the Japanese population. PLOS ONE. 2017; 12 (11): e0185487. doi:10.1371/journal.pone.0185487  
539.   Hayashi Yohei, Otsuka Kei, Ebina Masayuki, et al. Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells. Proceedings of the National Academy of Sciences. 2017; 114 (31): 8289-8294. doi:10.1073/pnas.1620915114  
540.   Fujiwara Masaki, Inagaki Masatoshi, Nakaya Naoki, et al. Cancer screening participation in schizophrenic outpatients and the influence of their functional disability on the screening rate: A cross-sectional study in Japan. Psychiatry and Clinical Neurosciences. 2017; 71 (12): 813-825. doi:10.1111/pcn.12554  
541.   Tsuchiya Naho, Nakaya Naoki, Nakamura Tomohiro, et al. Impact of social capital on psychological distress and interaction with house destruction and displacement after the Great East Japan Earthquake of 2011. Psychiatry and Clinical Neurosciences. 2017; 71 (1): 52-60. doi:10.1111/pcn.12467  
542.   Nezu Masahiro, Souma Tomokazu, Yu Lei, et al. Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. Science Signaling. 2017; 10 (479): eaam5711. doi:10.1126/scisignal.aam5711  
543.   Noguchi Shuhei, Arakawa Takahiro, Fukuda Shiro, et al. FANTOM5 CAGE profiles of human and mouse samples. Scientific Data. 2017; 4 : 170112. doi:10.1038/sdata.2017.112  
544.   Shima Hisato, Sasaki Kensuke, Suzuki Takehiro, et al. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways. Scientific Reports. 2017; 7 (1): 1884. doi:10.1038/s41598-017-01702-7  
545.   Kano Michiko, Muratsubaki Tomohiko, Van Oudenhove Lukas, et al. Altered brain and gut responses to corticotropin-releasing hormone (CRH) in patients with irritable bowel syndrome. Scientific Reports. 2017; 7 (1): 12425. doi:10.1038/s41598-017-09635-x  
546.   Ueno Kazuko, Iwagawa Toshiro, Ochiai Genki, et al. Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse. Scientific Reports. 2017; 7 (1): 3578. doi:10.1038/s41598-017-03874-8  
547.   Yamamoto Satoshi, Masuda Reiji, Sato Yukuto, et al. Environmental DNA metabarcoding reveals local fish communities in a species-rich coastal sea. Scientific Reports. 2017; 7 (1): 40368. doi:10.1038/srep40368  
548.   Hachiya Tsuyoshi, Komaki Shohei, Hasegawa Yutaka, et al. Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c. Scientific Reports. 2017; 7 (1): 16147. doi:10.1038/s41598-017-16493-0  
549.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Global associations between regional gray matter volume and diverse complex cognitive functions: evidence from a large sample study. Scientific Reports. 2017; 7 (1): 10014. doi:10.1038/s41598-017-10104-8  
550.   Hitomi Yuki, Kojima Kaname, Kawashima Minae, et al. Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis. Scientific Reports. 2017; 7 (1): 2904. doi:10.1038/s41598-017-03067-3  
551.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Neural plasticity in amplitude of low frequency fluctuation, cortical hub construction, regional homogeneity resulting from working memory training. Scientific Reports. 2017; 7 (1): 1470. doi:10.1038/s41598-017-01460-6  
552.   Hachiya Tsuyoshi, Kamatani Yoichiro, Takahashi Atsushi, et al. Genetic Predisposition to Ischemic Stroke. Stroke. 2017; 48 (2): 253-258. doi:10.1161/STROKEAHA.116.014506  
553.   Sawada Ikumi, Alejandria Marissa, Do Cuong D., et al. Regional Differences in the Prevalence of Major Opportunistic Infections among Antiretroviral-Naïve Human Immunodeficiency Virus Patients in Japan, Northern Thailand, Northern Vietnam, and the Philippines. The American Journal of Tropical Medicine and Hygiene. 2017; 97 (1): 49-56. doi:10.4269/ajtmh.16-0783  
554.   Obara Taku, Nishigori Hidekazu, Nishigori Toshie, et al. Prevalence and determinants of inadequate use of folic acid supplementation in Japanese pregnant women: the Japan Environment and Children’s Study (JECS). The Journal of Maternal-Fetal & Neonatal Medicine. 2017; 30 (5): 588-593. doi:10.1080/14767058.2016.1179273  
555.   Ishikuro Mami, Ramón Gutiérrez Ubeda Sergio, Obara Taku, et al. Exploring Risk Factors of Patient Falls: A Retrospective Hospital Record Study in Japan. The Tohoku Journal of Experimental Medicine. 2017; 243 (3): 195-203. doi:10.1620/tjem.243.195  
556.   Nakaya Naoki, Sone Toshimasa, Nakaya Kumi, et al. Psychological Distress among Individuals Whose Partners Have Cancer. The Tohoku Journal of Experimental Medicine. 2017; 243 (1): 27-33. doi:10.1620/tjem.243.27  
557.   Nah Kyeongah, Nishiura Hiroshi, Tsuchiya Naho, et al. Test-and-treat approach to HIV/AIDS: a primer for mathematical modeling. Theoretical Biology and Medical Modelling. 2017; 14 (1): 16. doi:10.1186/s12976-017-0062-9  
558.   純 安田. 【リファレンス情報とその活用の展望】全ゲノムリファレンスパネルが変える,近未来の日本のゲノム医療―遺伝性腫瘍へのインパクト. 医学のあゆみ. 2017; 260 ((11)): 943-948.  
559.   Sakai Mai, Takahashi Yuta, Yu Zhiqian, Tomita Hiroaki. Microglial Gene Expression Alterations in the Brains of Patients with Psychiatric Disorders. Advances in Neuroimmune Biology. 2016; 6 (2): 83-93. doi:10.3233/NIB-160110  
560.   Matsuo Hirotaka, Yamamoto Ken, Nakaoka Hirofumi, et al. Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes. Annals of the Rheumatic Diseases. 2016; 75 (4): 652-659. doi:10.1136/annrheumdis-2014-206191  
561.   Zhang Qi, Matsui Hiroyuki, Horiuchi Hisanori, et al. A-Raf and C-Raf differentially regulate mechanobiological response of osteoblasts to guide mechanical stress-induced differentiation. Biochemical and Biophysical Research Communications. 2016; 476 (4): 438-444. doi:10.1016/j.bbrc.2016.05.141  
562.   Tadaka Shu, Kinoshita Kengo. NCMine: Core-peripheral based functional module detection using near-clique mining. Bioinformatics (Oxford, England). 2016; 32 (22): 3454-3460. doi:10.1093/bioinformatics/btw488  
563.   Kanoh Naoki, Mano Kosuke, Saigusa Daisuke, et al. Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate. Bioorganic & Medicinal Chemistry Letters. 2016; 26 (23): 5770-5772. doi:10.1016/j.bmcl.2016.10.046  
564.   Yamada Kazunori D, Nishi Hafumi, Nakata Junichi, Kinoshita Kengo. Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins. Biophysics and Physicobiology. 2016; 13 : 157-163. doi:10.2142/biophysico.13.0_157  
565.   Nariai Naoki, Kojima Kaname, Mimori Takahiro, et al. A Bayesian approach for estimating allele-specific expression from RNA-Seq data with diploid genomes. BMC Genomics. 2016; 17 (S1): 2. doi:10.1186/s12864-015-2295-5  
566.   Hasegawa Takanori, Kojima Kaname, Kawai Yosuke, et al. AP-SKAT: highly-efficient genome-wide rare variant association test. BMC Genomics. 2016; 17 (1): 745. doi:10.1186/s12864-016-3094-3  
567.   Kojima Kaname, Kawai Yosuke, Nariai Naoki, et al. Short tandem repeat number estimation from paired-end reads for multiple individuals by considering coalescent tree. BMC Genomics. 2016; 17 (S5): 494. doi:10.1186/s12864-016-2821-0  
568.   Kojima Kaname, Kawai Yosuke, Misawa Kazuharu, et al. STR-realigner: a realignment method for short tandem repeat regions. BMC Genomics. 2016; 17 (1): 991. doi:10.1186/s12864-016-3294-x  
569.   Nishi Daisuke, Su Kuan-Pin, Usuda Kentaro, et al. The synchronized trial on expectant mothers with depressive symptoms by omega-3 PUFAs (SYNCHRO): Study protocol for a randomized controlled trial. BMC psychiatry. 2016; 16 (1): 321. doi:10.1186/s12888-016-1031-2  
570.   Okayama Akira, Okuda Nagako, Miura Katsuyuki, et al. Dietary sodium-to-potassium ratio as a risk factor for stroke, cardiovascular disease and all-cause mortality in Japan: the NIPPON DATA80 cohort study. BMJ Open. 2016; 6 (7): e011632. doi:10.1136/bmjopen-2016-011632  
571.   Yokomichi Hiroshi, Zheng Wei, Matsubara Hiroko, et al. Impact of the great east Japan earthquake on the body mass index of preschool children: a nationwide nursery school survey. BMJ Open. 2016; 6 (4): e010978. doi:10.1136/bmjopen-2015-010978  
572.   Akimoto Yoritaka, Nozawa Takayuki, Kanno Akitake, et al. High-gamma power changes after cognitive intervention: preliminary results from twenty-one senior adult subjects. Brain and Behavior. 2016; 6 (3): e00427. doi:10.1002/brb3.427  
573.   Satoh H., Moriguchi T., Saigusa D., et al. NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth. Cancer Research. 2016; 76 (10): 3088-3096. doi:10.1158/0008-5472.CAN-15-1584  
574.   Hashimoto Teruo, Fukui Kento, Takeuchi Hikaru, et al. Effects of the BDNF Val66Met Polymorphism on Gray Matter Volume in Typically Developing Children and Adolescents. Cerebral Cortex. 2016; 26 (4): 1795-1803. doi:10.1093/cercor/bhw020  
575.   Hattori Motoshi, Iwano Masayuki, Sako Mayumi, et al. Transition of adolescent and young adult patients with childhood-onset chronic kidney disease from pediatric to adult renal services: a nationwide survey in Japan. Clinical and Experimental Nephrology. 2016; 20 (6): 918-925. doi:10.1007/s10157-016-1231-6  
576.   Nakano Tadashi, Mizoue Shiro, Fuse Nobuo, et al. Fixed combination of travoprost and timolol maleate reduces intraocular pressure in Japanese patients with primary open-angle glaucoma or ocular hypertension: analysis by prostaglandin analogue. Clinical Ophthalmology. 2016; Volume 11 : 55-61. doi:10.2147/OPTH.S120639  
577.   Nakamura Tomohiro, Yamamoto Yoshiro, Douke Hideyuki. Sequential Hypothesis Tests for Identifying the Minimum Dose with a Threshold Effect. Communications in Statistics - Simulation and Computation. 2016; 45 (6): 1950-1970. doi:10.1080/03610918.2014.884588  
578.   Shirota Matsuyuki, Kinoshita Kengo. Discrepancies between human DNA, mRNA and protein reference sequences and their relation to single nucleotide variants in the human population. Database. 2016; 2016 : baw124. doi:10.1093/database/baw124  
579.   Mizuno Satoshi, Nishigori Hidekazu, Sugiyama Takashi, et al. Association between social capital and the prevalence of gestational diabetes mellitus: An interim report of the Japan Environment and Children’s Study. Diabetes Research and Clinical Practice. 2016; 120 : 132-141. doi:10.1016/j.diabres.2016.07.020  
580.   Mishima Eikan, Takeuchi Yoichi, Nagasawa Tasuku, Hashimoto Junichiro. Prelude to Takotsubo cardiomyopathy: subclinical progression of antecedent myocardial ischaemia prior to symptom onset. European Heart Journal. 2016; 37 (37): 2845-2845. doi:10.1093/eurheartj/ehw216  
581.   Kawabe Takeshi, Suzuki Nobu, Yamaki Satoshi, et al. Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the small intestine in mice. European Journal of Immunology. 2016; 46 (5): 1119-1131. doi:10.1002/eji.201545907  
582.   Otsuki Akihito, Suzuki Mikiko, Katsuoka Fumiki, et al. Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection. Free Radical Biology and Medicine. 2016; 91 : 45-57. doi:10.1016/j.freeradbiomed.2015.12.005  
583.   Takahashi Yuta, Yu Zhiqian, Sakai Mai, Tomita Hiroaki. Linking Activation of Microglia and Peripheral Monocytic Cells to the Pathophysiology of Psychiatric Disorders. Frontiers in Cellular Neuroscience. 2016; 10 : . doi:10.3389/fncel.2016.00144  
584.   Nouchi Rui, Taki Yasuyuki, Takeuchi Hikaru, et al. Reading Aloud and Solving Simple Arithmetic Calculation Intervention (Learning Therapy) Improves Inhibition, Verbal Episodic Memory, Focus Attention and Processing Speed in Healthy Elderly People: Evidence from a Randomized Controlled Trial. Frontiers in Human Neuroscience. 2016; 10 : . doi:10.3389/fnhum.2016.00217  
585.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Sex-Related Differences in the Effects of Sleep Habits on Verbal and Visuospatial Working Memory. Frontiers in Psychology. 2016; 7 : 1128. doi:10.3389/fpsyg.2016.01128  
586.   Katsuoka Fumiki, Yamamoto Masayuki. Small Maf proteins (MafF, MafG, MafK): History, structure and function. Gene. 2016; 586 (2): 197-205. doi:10.1016/j.gene.2016.03.058  
587.   Katsuoka Fumiki, Yamazaki Hiromi, Yamamoto Masayuki. Small Maf deficiency recapitulates the liver phenotypes of Nrf1- and Nrf2-deficient mice. Genes to Cells. 2016; 21 (12): 1309-1319. doi:10.1111/gtc.12445  
588.   Ueki Masao, Tamiya Gen. Smooth-Threshold Multivariate Genetic Prediction with Unbiased Model Selection. Genetic Epidemiology. 2016; 40 (3): 233-243. doi:10.1002/gepi.21958  
589.   Koso Hideto, Tsuhako Asano, Lai Chen-Yi, et al. Conditional rod photoreceptor ablation reveals Sall1 as a microglial marker and regulator of microglial morphology in the retina. Glia. 2016; 64 (11): 2005-24. doi:10.1002/glia.23038  
590.   Ishikuro Mami, Ubeda Sergio Ramón Gutiérrez, Obara Taku, et al. Knowledge, Attitude, and Practices Toward Blood Pressure Measurement at Home Among Japanese Nurses. Home Healthcare Now. 2016; 34 (4): 210-217. doi:10.1097/NHH.0000000000000357  
591.   Arai-Ichinoi Natsuko, Uematsu Mitsugu, Sato Ryo, et al. Genetic heterogeneity in 26 infants with a hypomyelinating leukodystrophy. Human Genetics. 2016; 135 (1): 89-98. doi:10.1007/s00439-015-1617-7  
592.   Yaoita Masako, Niihori Tetsuya, Mizuno Seiji, et al. Spectrum of mutations and genotype–phenotype analysis in Noonan syndrome patients with RIT1 mutations. Human Genetics. 2016; 135 (2): 209-222. doi:10.1007/s00439-015-1627-5  
593.   Satoh Michihiro, Asayama Kei, Kikuya Masahiro, et al. Long-Term Stroke Risk Due to Partial White-Coat or Masked Hypertension Based on Home and Ambulatory Blood Pressure Measurements: The Ohasama Study. Hypertension. 2016; 67 (1): 48-55. doi:10.1161/HYPERTENSIONAHA.115.06461  
594.   Kogure Mana, Tsuchiya Naho, Hozawa Atsushi, et al. Does the flushing response modify the relationship between alcohol intake and hypertension in the Japanese population? NIPPON DATA2010. Hypertension Research. 2016; 39 (9): 670-679. doi:10.1038/hr.2016.46  
595.   Ishikura Kazuki, Obara Taku, Kikuya Masahiro, et al. Home blood pressure level and decline in renal function among treated hypertensive patients: the J-HOME-Morning Study. Hypertension Research. 2016; 39 (2): 107-112. doi:10.1038/hr.2015.110  
596.   Iwama Noriyuki, Metoki Hirohito, Ohkubo Takayoshi, et al. Maternal clinic and home blood pressure measurements during pregnancy and infant birth weight: the BOSHI study. Hypertension Research. 2016; 39 (3): 151-157. doi:10.1038/hr.2015.108  
597.   Ntineri Angeliki, Stergiou George S, Thijs Lutgarde, et al. Relationship between office and home blood pressure with increasing age: The International Database of HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO). Hypertension Research. 2016; 39 (8): 612-617. doi:10.1038/hr.2016.32  
598.   Watanabe Ko, Tanaka Hiroshi, Takahashi Kensho, et al. NIRS-Based Language Learning BCI System. IEEE Sensors Journal. 2016; 16 (8): 2726-2734. doi:10.1109/JSEN.2016.2519886  
599.   Matsubayashi Makoto, Kawahara Fumiya, Hatta Takeshi, et al. Transcriptional profiles of virulent and precocious strains of Eimeria tenella at sporozoite stage; novel biological insight into attenuated asexual development. Infection, Genetics and Evolution. 2016; 40 : 54-62. doi:10.1016/j.meegid.2016.02.021  
600.   Mashimo Yoichi, Sakurai-Yageta Mika, Watanabe Misa, et al. Induction of the Matrix Metalloproteinase 13 Gene in Bronchial Epithelial Cells by Interferon and Identification of its Novel Functional Polymorphism. Inflammation. 2016; 39 (3): pp 949–962. doi:10.1007/s10753-015-0291-1  
601.   Chagan-Yasutan Haorile, Chen Yue, Lacuesta Talitha, et al. Urine Levels of Defensin α1 Reflect Kidney Injury in Leptospirosis Patients. International Journal of Molecular Sciences. 2016; 17 (10): 1637. doi:10.3390/ijms17101637  
602.   Watanabe Zen, Iwama Noriyuki, Nishigori Hidekazu, et al. Psychological distress during pregnancy in Miyagi after the Great East Japan Earthquake: The Japan Environment and Children's Study. Journal of Affective Disorders. 2016; 190 : 341-348. doi:10.1016/j.jad.2015.10.024  
603.   Hirata Aya, Okamura Tomonori, Sugiyama Daisuke, et al. The Relationship between Very High Levels of Serum High-Density Lipoprotein Cholesterol and Cause-Specific Mortality in a 20-Year Follow-Up Study of Japanese General Population. Journal of Atherosclerosis and Thrombosis. 2016; 23 (7): 800-809. doi:10.5551/jat.33449  
604.   Kubota Yoshiko, Nomura Kazumi, Katoh Yasutake, et al. Novel Mechanisms for Heme-dependent Degradation of ALAS1 Protein as a Component of Negative Feedback Regulation of Heme Biosynthesis. Journal of Biological Chemistry. 2016; 291 (39): 20516-20529. doi:10.1074/jbc.M116.719161  
605.   Araki Yuta, Okamura Ken, Munkhbat Batmunkh, et al. Whole-exome sequencing confirmation of multiple MC1R variants associated with extensive freckles and red hair: Analysis of a Mongolian family. Journal of Dermatological Science. 2016; 84 (2): 216-219. doi:10.1016/j.jdermsci.2016.08.009  
606.   Matsubara Hiroko, Ishikuro Mami, Kikuya Masahiro, et al. Design of the Nationwide Nursery School Survey on Child Health Throughout the Great East Japan Earthquake. Journal of Epidemiology. 2016; 26 (2): 98-104. doi:10.2188/jea.JE20150073  
607.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268  
608.   Ogino Daisuke, Hashimoto Taeko, Hattori Motoshi, et al. Analysis of the genes responsible for steroid-resistant nephrotic syndrome and/or focal segmental glomerulosclerosis in Japanese patients by whole-exome sequencing analysis. Journal of Human Genetics. 2016; 61 (2): 137-141. doi:10.1038/jhg.2015.122  
609.   Sato Emiko, Tsunokuni Yukako, Fushima Tomofumi, et al. OS 08-06 METABOLOMIC ANALYSIS OF A MOUSE MODEL OF PREECLAMPSIA INDUCED BY OVERPRODUCING sFlt-1. Journal of Hypertension. 2016; 34 (Supplement 1): e69. doi:10.1097/01.hjh.0000500031.24401.46  
610.   Satoh Michihiro, Haga Toshikazu, Hosaka Miki, et al. The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements. Journal of Hypertension. 2016; 34 (6): 1218-1223. doi:10.1097/HJH.0000000000000902  
611.   Juhanoja Eeva, Johansson Jouni, Thijs Lutgarde, et al. YIA 01-03 OUTCOME-DRIVEN REFERENCE FRAME FOR SELF-MEASURED HOME BLOOD PRESSURE VARIABILITY. Journal of Hypertension. 2016; 34 (Supplement 1): e36. doi:10.1097/01.hjh.0000499951.86351.ac  
612.   Kakazu Eiji, Mauer Amy S, Yin Meng, Malhi Harmeet. Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1$α$-dependent manner. Journal of Lipid Research. 2016; 57 (2): 233-245. doi:10.1194/jlr.M063412  
613.   Kakazu Eiji, Mauer Amy S., Yin Meng, Malhi Harmeet. Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. Journal of Lipid Research. 2016; 57 (2): 233-245. doi:10.1194/jlr.M063412  
614.   Murakami Yoichi, Omori Satoshi, Kinoshita Kengo. NLDB: a database for 3D protein–ligand interactions in enzymatic reactions. Journal of Structural and Functional Genomics. 2016; 17 (4): 101-110. doi:10.1007/s10969-016-9206-0  
615.   Gojobori Takashi, Ikeo Kazuho, Katayama Yukie, et al. VaProS: a database-integration approach for protein/genome information retrieval. Journal of Structural and Functional Genomics. 2016; 17 (4): 69-81. doi:10.1007/s10969-016-9211-3  
616.   Komiyama Takamasa, Ohi Takashi, Miyoshi Yoshitada, et al. Association Between Tooth Loss, Receipt of Dental Care, and Functional Disability in an Elderly Japanese Population: The Tsurugaya Project. Journal of the American Geriatrics Society. 2016; 64 (12): 2495-2502. doi:10.1111/jgs.14390  
617.   Mishima Eikan, Nishimiya Kensuke, Fujiwara Yasushi, et al. Serious Hypocalcemia After Withdrawal of Vitamin D Analog in Bedridden Nonagenarians with Previous Thyroidectomy: A Report of Two Cases. Journal of the American Geriatrics Society. 2016; 64 (6): 1374-1376. doi:10.1111/jgs.14171  
618.   Suzuki T., Yamaguchi H., Kikusato M., et al. Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. Journal of the American Society of Nephrology. 2016; 27 (7): 1925-1932. doi:10.1681/ASN.2015060623  
619.   Maekawa Masamitsu, Omura Kaoru, Sekiguchi Shoutaro, et al. Identification of Two Sulfated Cholesterol Metabolites Found in the Urine of a Patient with Niemann–Pick Disease Type C as Novel Candidate Diagnostic Markers. Mass Spectrometry. 2016; 5 (2): S0053-S0053. doi:10.5702/massspectrometry.S0053  
620.   Kitatani Kazuyuki, Iwabuchi Kazuhisa, Snider Ashley, Riboni Laura. Sphingolipids in Inflammation: From Bench to Bedside. Mediators of Inflammation. 2016; 2016 : 1-2. doi:10.1155/2016/7602526  
621.   Ogishima Soichi, Mizuno Satoshi, Kikuchi Masataka, et al. AlzPathway, an Updated Map of Curated Signaling Pathways: Towards Deciphering Alzheimer’s Disease Pathogenesis. Methods in molecular biology (Clifton, N.J.). 2016; 1303 : 423-432. doi:10.1007/978-1-4939-2627-5_25  
622.   Kikuchi Masataka, Ogishima Soichi, Mizuno Satoshi, et al. Network-Based Analysis for Uncovering Mechanisms Underlying Alzheimer’s Disease. Methods in molecular biology (Clifton, N.J.). 2016; 1303 : 479-491. doi:10.1007/978-1-4939-2627-5_29  
623.   Iso Tatsuro, Suzuki Takafumi, Baird Liam, Yamamoto Masayuki. Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells. Molecular and Cellular Biology. 2016; 36 (24): 3100-3112. doi:10.1128/MCB.00389-16  
624.   Hasegawa Atsushi, Kaneko Hiroshi, Ishihara Daishi, et al. GATA1 Binding Kinetics on Conformation-Specific Binding Sites Elicit Differential Transcriptional Regulation. Molecular and Cellular Biology. 2016; 36 (16): 2151-2167. doi:10.1128/MCB.00017-16  
625.   Uruno Akira, Yagishita Yoko, Katsuoka Fumiki, et al. Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism. Molecular and Cellular Biology. 2016; 36 (11): 1655-1672. doi:10.1128/MCB.01095-15  
626.   Sekine Hiroki, Okazaki Keito, Ota Nao, et al. The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression. Molecular and Cellular Biology. 2016; 36 (3): 407-420. doi:10.1128/MCB.00785-15  
627.   Shimada Makoto K., Sanbonmatsu Ryoko, Yamaguchi-Kabata Yumi, et al. Selection pressure on human STR loci and its relevance in repeat expansion disease. Molecular Genetics and Genomics. 2016; 291 (5): 1851-1869. doi:10.1007/s00438-016-1219-7  
628.   Takeuchi H, Taki Y, Hashizume H, et al. Impact of videogame play on the brain’s microstructural properties: cross-sectional and longitudinal analyses. Molecular Psychiatry. 2016; 21 (12): 1781-1789. doi:10.1038/mp.2015.193  
629.   Matsumoto Akinobu, Pasut Alessandra, Matsumoto Masaki, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2016; 541 (7636): 228-232. doi:10.1038/nature21034  
630.   Kobayashi Eri H., Suzuki Takafumi, Funayama Ryo, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nature Communications. 2016; 7 : 11624. doi:10.1038/ncomms11624  
631.   Hidaka Takanori, Ogawa Eisaku, Kobayashi Eri H, et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nature Immunology. 2016; 18 (1): 64-73. doi:10.1038/ni.3614  
632.   Murakami Keiko, Metoki Hirohito, Satoh Michihiro, et al. Menstrual Factors and Stroke Incidence in Japanese Postmenopausal Women: The Ohasama Study. Neuroepidemiology. 2016; 47 (2): 109-116. doi:10.1159/000452220  
633.   Takeuchi Hikaru, Taki Yasuyuki, Hashizume Hiroshi, et al. Impact of reading habit on white matter structure: Cross-sectional and longitudinal analyses. NeuroImage. 2016; 133 : 378-389. doi:10.1016/j.neuroimage.2016.03.037  
634.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Unemployment risk among individuals undergoing medical treatment for chronic diseases. Occupational Medicine. 2016; 66 (2): 143-149. doi:10.1093/occmed/kqv159  
635.   Shigeta S, Toyoshima M, Kitatani K, et al. Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer. Oncogene. 2016; 35 (27): 3577-86. doi:10.1038/onc.2015.425  
636.   Masamune Atsushi, Nakano Eriko, Niihori Tetsuya, et al. Variants in the UBR1 gene are not associated with chronic pancreatitis in Japan. Pancreatology. 2016; 16 (5): 814-818. doi:10.1016/j.pan.2016.06.662  
637.   Aoki Yuichi, Okamura Yasunobu, Ohta Hiroyuki, et al. ALCOdb: Gene Coexpression Database for Microalgae. Plant and Cell Physiology. 2016; 57 (1): e3-e3. doi:10.1093/pcp/pcv190  
638.   Aoki Yuichi, Okamura Yasunobu, Tadaka Shu, et al. ATTED-II in 2016: A Plant Coexpression Database Towards Lineage-Specific Coexpression. Plant and Cell Physiology. 2016; 57 (1): e5-e5. doi:10.1093/pcp/pcv165  
639.   Kohda Masakazu, Tokuzawa Yoshimi, Kishita Yoshihito, et al. A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies. PLOS Genetics. 2016; 12 (1): e1005679. doi:10.1371/journal.pgen.1005679  
640.   Watanabe Masahiro, Hashimoto Koichi, Abe Yusaku, et al. A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo. PLOS ONE. 2016; 11 (9): e0162823. doi:10.1371/journal.pone.0162823  
641.   Shiwa Yuh, Hachiya Tsuyoshi, Furukawa Ryohei, et al. Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols. PLOS ONE. 2016; 11 (1): e0147519. doi:10.1371/journal.pone.0147519  
642.   Sasaki Ayaka, Sato Naoko, Suzuki Naoki, et al. Associations between Single-Nucleotide Polymorphisms in Corticotropin-Releasing Hormone-Related Genes and Irritable Bowel Syndrome. PLOS ONE. 2016; 11 (2): e0149322. doi:10.1371/journal.pone.0149322  
643.   Yamagishi Junya, Sato Yukuto, Shinozaki Natsuko, et al. Comparison of Boiling and Robotics Automation Method in DNA Extraction for Metagenomic Sequencing of Human Oral Microbes. PLOS ONE. 2016; 11 (4): e0154389. doi:10.1371/journal.pone.0154389  
644.   Komuro Hazuki, Sato Naoko, Sasaki Ayaka, et al. Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome. PLOS ONE. 2016; 11 (1): e0147817. doi:10.1371/journal.pone.0147817  
645.   Tanaka Yukari, Kanazawa Motoyori, Kano Michiko, et al. Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome. PLOS ONE. 2016; 11 (7): e0157347. doi:10.1371/journal.pone.0157347  
646.   Kimura Yasumasa, Soma Takahiro, Kasahara Naoko, et al. Edesign: Primer and Enhanced Internal Probe Design Tool for Quantitative PCR Experiments and Genotyping Assays. PLOS ONE. 2016; 11 (2): e0146950. doi:10.1371/journal.pone.0146950  
647.   Kuragano Takahiro, Kitamura Kenichiro, Matsumura Osamu, et al. ESA Hyporesponsiveness Is Associated with Adverse Events in Maintenance Hemodialysis (MHD) Patients, But Not with Iron Storage. PLOS ONE. 2016; 11 (3): e0147328. doi:10.1371/journal.pone.0147328  
648.   Saigusa Daisuke, Okamura Yasunobu, Motoike Ikuko N., et al. Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery. PLOS ONE. 2016; 11 (8): e0160555. doi:10.1371/journal.pone.0160555  
649.   Kasahara Kota, Kinoshita Kengo. IBiSA_Tools: A Computational Toolkit for Ion-Binding State Analysis in Molecular Dynamics Trajectories of Ion Channels. PLOS ONE. 2016; 11 (12): e0167524. doi:10.1371/journal.pone.0167524  
650.   Uranbileg Baasanjav, Ikeda Hitoshi, Kurano Makoto, et al. Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. PLOS ONE. 2016; 11 (2): e0149462. doi:10.1371/journal.pone.0149462  
651.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Ion Concentration- and Voltage-Dependent Push and Pull Mechanisms of Potassium Channel Ion Conduction. PLOS ONE. 2016; 11 (3): e0150716. doi:10.1371/journal.pone.0150716  
652.   Mizuno Satoshi, Ogishima Soichi, Kitatani Kazuyuki, et al. Network Analysis of a Comprehensive Knowledge Repository Reveals a Dual Role for Ceramide in Alzheimer’s Disease. PLOS ONE. 2016; 11 (2): e0148431. doi:10.1371/journal.pone.0148431  
653.   Matsudaira Izumi, Yokota Susumu, Hashimoto Teruo, et al. Parental Praise Correlates with Posterior Insular Cortex Gray Matter Volume in Children and Adolescents. PLOS ONE. 2016; 11 (4): e0154220. doi:10.1371/journal.pone.0154220  
654.   Mizuno Satoshi, Ogishima Soichi, Nishigori Hidekazu, et al. The Pre-Eclampsia Ontology: A Disease Ontology Representing the Domain Knowledge Specific to Pre-Eclampsia. PLOS ONE. 2016; 11 (10): e0162828. doi:10.1371/journal.pone.0162828  
655.   Sugawara Junichi, Hoshiai Tetsuro, Sato Kazuyo, et al. Impact of the Great East Japan Earthquake on Regional Obstetrical Care in Miyagi Prefecture. Prehospital and Disaster Medicine. 2016; 31 (3): 255-258. doi:10.1017/S1049023X1600025X  
656.   Ishikuro Mami, Nakaya Naoki, Obara Taku, et al. Public Attitudes toward an Epidemiological Study with Genomic Analysis in the Great East Japan Earthquake Disaster Area. Prehospital and Disaster Medicine. 2016; 31 (3): 330-334. doi:10.1017/S1049023X16000182  
657.   Li Feng, Fushima Tomofumi, Oyanagi Gen, et al. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proceedings of the National Academy of Sciences. 2016; 113 (47): 13450-13455. doi:10.1073/pnas.1614947113  
658.   Salie Zhe Li, Kirby Karen A., Michailidis Eleftherios, et al. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA). Proceedings of the National Academy of Sciences. 2016; 113 (33): 9274-9279. doi:10.1073/pnas.1605223113  
659.   Nishi Hafumi, Nakata Junichi, Kinoshita Kengo. Distribution of single-nucleotide variants on protein-protein interaction sites and its relationship with minor allele frequency. Protein Science. 2016; 25 (2): 316-321. doi:10.1002/pro.2845  
660.   Kasahara Kota, Kinoshita Kengo. Landscape of protein-small ligand binding modes. Protein Science. 2016; 25 (9): 1659-1671. doi:10.1002/pro.2971  
661.   Nishi Daisuke, Su Kuan-Pin, Usuda Kentaro, et al. Omega-3 fatty acid supplementation for expectant mothers with depressive symptoms in Japan and Taiwan: An open-label trial. Psychiatry and Clinical Neurosciences. 2016; 70 (6): 253-254. doi:10.1111/pcn.12388  
662.   Yoshida Hirokazu, Kobayashi Natsuko, Honda Nami, et al. Post-traumatic growth of children affected by the Great East Japan Earthquake and their attitudes to memorial services and media coverage. Psychiatry and Clinical Neurosciences. 2016; 70 (5): 193-201. doi:10.1111/pcn.12379  
663.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Prospect of future housing and risk of psychological distress at 1 year after an earthquake disaster. Psychiatry and Clinical Neurosciences. 2016; 70 (4): 182-189. doi:10.1111/pcn.12377  
664.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Basal ganglia correlates of fatigue in young adults. Scientific Reports. 2016; 6 (1): 21386. doi:10.1038/srep21386  
665.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Differences in gray matter structure correlated to nationalism and patriotism. Scientific Reports. 2016; 6 (1): 29912. doi:10.1038/srep29912  
666.   Nakagawa Seishu, Sugiura Motoaki, Sekiguchi Atsushi, et al. Effects of post-traumatic growth on the dorsolateral prefrontal cortex after a disaster. Scientific Reports. 2016; 6 (1): 34364. doi:10.1038/srep34364  
667.   Sun Yonghu, Irwanto Astrid, Toyo-oka Licht, et al. Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn’s disease and leprosy. Scientific Reports. 2016; 6 (1): 31429. doi:10.1038/srep31429  
668.   Sato Emiko, Mori Takefumi, Mishima Eikan, et al. Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease. Scientific Reports. 2016; 6 (1): 36618. doi:10.1038/srep36618  
669.   Nouchi Rui, Takeuchi Hikaru, Taki Yasuyuki, et al. Neuroanatomical bases of effortful control: evidence from a large sample of young healthy adults using voxel-based morphometry. Scientific Reports. 2016; 6 (1): 31231. doi:10.1038/srep31231  
670.   Sekiguchi Atsushi, Sato Chiho, Matsudaira Izumi, et al. Postoperative hormonal therapy prevents recovery of neurological damage after surgery in patients with breast cancer. Scientific Reports. 2016; 6 (1): 34671. doi:10.1038/srep34671  
671.   Sato Masaya, Ikeda Hitoshi, Uranbileg Baasanjav, et al. Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human. Scientific Reports. 2016; 6 (1): 32119. doi:10.1038/srep32119  
672.   Fujiwara Yuichiro, Kondo Hiroko X., Shirota Matsuyuki, et al. Structural basis for the membrane association of ankyrinG via palmitoylation. Scientific Reports. 2016; 6 (1): 23981. doi:10.1038/srep23981  
673.   Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463  
674.   Ueno Kazuko, Iwagawa Toshiro, Kuribayashi Hiroshi, et al. Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation. Scientific Reports. 2016; 6 (1): 29264. doi:10.1038/srep29264  
675.   Oba Kentaro, Noriuchi Madoka, Atomi Tomoaki, et al. Memory and reward systems coproduce ‘nostalgic’ experiences in the brain. Social Cognitive and Affective Neuroscience. 2016; 11 (7): 1069-1077. doi:10.1093/scan/nsv073  
676.   Hanawa Sugiko, Sugiura Motoaki, Nozawa Takayuki, et al. The neural basis of the imitation drive. Social Cognitive and Affective Neuroscience. 2016; 11 (1): 66-77. doi:10.1093/scan/nsv089  
677.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Longitudinal association between time-varying social isolation and psychological distress after the Great East Japan Earthquake. Social Science & Medicine. 2016; 152 : 96-101. doi:10.1016/j.socscimed.2016.01.037  
678.   Murakami Keiko, Tsubota-Utsugi Megumi, Satoh Michihiro, et al. Impaired Higher-Level Functional Capacity as a Predictor of Stroke in Community-Dwelling Older Adults. Stroke. 2016; 47 (2): 323-328. doi:10.1161/STROKEAHA.115.011131  
679.   Takahashi Fumiaki, Nishigori Hidekazu, Nishigori Toshie, et al. Fermented Food Consumption and Psychological Distress in Pregnant Women: A Nationwide Birth Cohort Study of the Japan Environment and Children’s Study. The Tohoku Journal of Experimental Medicine. 2016; 240 (4): 309-321. doi:10.1620/tjem.240.309  
680.   Nakaya Naoki, Narita Akira, Tsuchiya Naho, et al. Partners’ Ongoing Treatment for Chronic Disease and the Risk of Psychological Distress after the Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2016; 239 (4): 307-314. doi:10.1620/tjem.239.307  
681.   Stagg H R, Harris R J, Hatherell H-A, et al. What are the most efficacious treatment regimens for isoniazid-resistant tuberculosis? A systematic review and network meta-analysis. Thorax. 2016; 71 (10): 940-949. doi:10.1136/thoraxjnl-2015-208262  
682.   Satoh Michihiro, Obara Taku, Nishigori Hidekazu, et al. Prescription trends in children with pervasive developmental disorders: a claims data-based study in Japan. World Journal of Pediatrics. 2016; 12 (4): 443-449. doi:10.1007/s12519-016-0036-8  
683.   相澤 弥生, 川目 裕. 遺伝カウンセラーにおける共感疲労、バーンアウトと共感満足 系統的レビュー. 日本遺伝カウンセリング学会誌. 2016; 37 : 21-30. http://search.jamas.or.jp/link/bc/20160721370002  
684.   相澤 弥生, 小林 朋子, 川目 裕. 網羅的ゲノム解析における偶発的所見を含む遺伝情報の結果の返却に関する我が国の現状と課題の検討 - 米国臨床遺伝・ゲノム学会 (ACMG) の偶発的所見取り扱いに関する推奨からの考察 -. 日本遺伝カウンセリング学会誌. 2016; 37(3) : 105 - 126. https://www.google.co.jp/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwiFlJC5zsnWAhVHm5QKHRZ8ASQQFggnMAA&url=https%3A%2F%2Fmol.medicalonline.jp%2Farchive%2Fselect%3Fjo%3Ddg8genco&usg=AFQjCNH2UmhYVh7WSBNqQlB4q9hwJq4L3A  
685.   T Obara, H Yamaguchi, M Satoh, Y Iida. Prevalence, Determinants, and Reasons for the Non-Reporting of Adverse Drug Reactions by Pharmacists in the Miyagi and Hokkaido Regions of Japan. Advances in Pharmacoepidemiology & Drug Safety. 2015; 04 (05): . doi:10.4172/2167-1052.1000191  
686.   Nakano Tadashi, Mizoue Shiro, Fuse Nobuo, et al. Fixed Combination of Travoprost and Timolol Maleate Reduces Intraocular Pressure in Japanese Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: A Prospective Multicenter Open-Label Study. Advances in Therapy. 2015; 32 (9): 823-837. doi:10.1007/s12325-015-0246-9  
687.   Satoh Michihiro, Kikuya Masahiro, Hosaka Miki, et al. Association of Aldosterone-to-Renin Ratio With Hypertension Differs by Sodium Intake: The Ohasama Study. American Journal of Hypertension. 2015; 28 (2): 208-215. doi:10.1093/ajh/hpu115  
688.   Niiranen Teemu J, Asayama Kei, Thijs Lutgarde, et al. Optimal Number of Days for Home Blood Pressure Measurement. American Journal of Hypertension. 2015; 28 (5): 595-603. doi:10.1093/ajh/hpu216  
689.   Iwamori Saki, Sato Emiko, Saigusa Daisuke, et al. A novel and sensitive assay for heme oxygenase activity. American Journal of Physiology-Renal Physiology. 2015; 309 (7): F667-F671. doi:10.1152/ajprenal.00210.2015  
690.   田中 由佳里, 福土 審. 脳画像と自律神経系ー消化管機能と脳機能画像. Annual Review 2015 神経. 2015; : 第3章--10:245--251. http://www.medbooks.or.jp/publications/?p_key=62353  
691.   Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, et al. Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method. Antiviral Chemistry and Chemotherapy. 2015; 24 (2): 77-82. doi:10.1177/2040206615614164  
692.   Nozawa Takayuki, Taki Yasuyuki, Kanno Akitake, et al. Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study. Behavioural Neurology. 2015; 2015 : 1-18. doi:10.1155/2015/525901  
693.   Takahashi Tomohiro, Saigusa Daisuke, Takeda Chihiro, et al. Determination of Sphingolipids by LC-MS/MS. Bioactive Lipid Mediators. 2015; : 357-370. doi:10.1007/978-4-431-55669-5_26  
694.   Nagaie Satoshi, Ogishima Soichi, Nakaya Jun, Tanaka Hiroshi. A method to associate all possible combinations of genetic and environmental factors using GxE landscape plot. Bioinformation. 2015; 11 (3): 161-4. doi:10.6026/97320630011161  
695.   Sawai Hashime, Takai-Igarashi Takako, Tanaka Hiroshi. Identification of collaborative activities with oxidative phosphorylation in bipolar disorder. Bioinformation. 2015; 11 (4): 207-216. doi:10.6026/97320630011207  
696.   Ogishima Soichi, Tanaka Hiroshi, Nakaya Jun. Modularity in the evolution of yeast protein interaction network. Bioinformation. 2015; 11 (3): 127-30. doi:10.6026/97320630011127  
697.   Watanabe Masanari, Noma Hisashi, Kurai Jun, et al. Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8. BioMed Research International. 2015; 2015 : 1-11. doi:10.1155/2015/583293  
698.   Cui Shuaiying, Tanabe Osamu, Sierant Michael, et al. Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes. Blood. 2015; 125 (9): 1477-87. doi:10.1182/blood-2014-10-605022  
699.   Mimori Takahiro, Nariai Naoki, Kojima Kaname, et al. Estimating copy numbers of alleles from population-scale high-throughput sequencing data. BMC Bioinformatics. 2015; 16 (S1): S4. doi:10.1186/1471-2105-16-S1-S4  
700.   Yamada Takeshi, Abei Masato, Danjoh Inaho, et al. Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib. BMC Cancer. 2015; 15 (1): 260. doi:10.1186/s12885-015-1297-7  
701.   Nariai Naoki, Kojima Kaname, Saito Sakae, et al. HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data. BMC Genomics. 2015; 16 (S2): S7. doi:10.1186/1471-2164-16-S2-S7  
702.   Endo Shun, Mishima Eikan, Takeuchi Yoichi, et al. Periodontitis-associated septic pulmonary embolism caused by Actinomyces species identified by anaerobic culture of bronchoalveolar lavage fluid: a case report. BMC Infectious Diseases. 2015; 15 (1): 552. doi:10.1186/s12879-015-1286-0  
703.   Sekiguchi Atsushi. [Self-esteem Saves Brain and Health: Evidence from a Follow-up Investigation after the Great East Japan Earthquake]. Brain and nerve = Shinkei kenkyu no shinpo. 2015; 67 (10): 1193-204. doi:10.11477/mf.1416200283  
704.   Hanajima R., Tanaka N, Tsutsumi R., et al. Age influence on the quadri-pulse stimulation (QPS) induced LTP like effect. Brain Stimulation. 2015; 8 (2): 335. doi:10.1016/j.brs.2015.01.084  
705.   Enomoto H, Kadowaki S, Abe M, et al. The inter-individual variability of quadripulse stimulation (QPS). Brain Stimulation. 2015; 8 (2): 336–337. doi:10.1016/j.brs.2015.01.089  
706.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Brain structures in the sciences and humanities. Brain Structure and Function. 2015; 220 (6): 3295-3305. doi:10.1007/s00429-014-0857-y  
707.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Working memory training impacts the mean diffusivity in the dopaminergic system. Brain Structure and Function. 2015; 220 (6): 3101-3111. doi:10.1007/s00429-014-0845-2  
708.   Minami Yuko, Hosokawa Toru, Nakaya Naoki, et al. Personality and breast cancer risk and survival: the Miyagi Cohort Study. Breast Cancer Research and Treatment. 2015; 150 (3): 675-684. doi:10.1007/s10549-015-3364-9  
709.   Mashiko Satsuki, Kitatani Kazuyuki, Toyoshima Masafumi, et al. Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer. Cancer Biology & Therapy. 2015; 16 (2): 253-260. doi:10.1080/15384047.2014.1001271  
710.   Mori Takahiro, Sumii Makiko, Fujishima Fumiyoshi, et al. Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma. Cancer Science. 2015; 106 (9): 1118-1129. doi:10.1111/cas.12722  
711.   Taniguchi M, Ogiso H, Takeuchi T, et al. Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis. Cell Death & Disease. 2015; 6 (4): e1717-e1717. doi:10.1038/cddis.2015.82  
712.   de Aguiar Vallim Thomas Q., Tarling Elizabeth J., Ahn Hannah, et al. MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism. Cell Metabolism. 2015; 21 (2): 298-311. doi:10.1016/j.cmet.2015.01.007  
713.   Takeuchi H., Taki Y., Hashizume H., et al. The Impact of Television Viewing on Brain Structures: Cross-Sectional and Longitudinal Analyses. Cerebral Cortex. 2015; 25 (5): 1188-1197. doi:10.1093/cercor/bht315  
714.   Metoki Hirohito, Obara Taku, Asayama Kei, et al. Differential effects of angiotensin II receptor blocker and losartan/hydrochlorothiazide combination on central blood pressure and augmentation index. Clinical and Experimental Hypertension. 2015; 37 (4): 294-302. doi:10.3109/10641963.2014.960972  
715.   Satoh Michihiro, Tanno Yumi, Hosaka Miki, et al. Salt intake and the validity of a salt intake assessment system based on a 24-h dietary recall method in pregnant Japanese women. Clinical and Experimental Hypertension. 2015; 37 (6): 459-462. doi:10.3109/10641963.2015.1057832  
716.   Usami Osamu, Nakajima Chie, Endo Shiro, et al. A case of Manila type Mycobacterium tuberculosis infection in Japan. Clinical Case Reports. 2015; 3 (7): 622-625. doi:10.1002/ccr3.277  
717.   Yokota Susumu, Takeuchi Hikaru, Hashimoto Teruo, et al. Individual differences in cognitive performance and brain structure in typically developing children. Developmental Cognitive Neuroscience. 2015; 14 : 1-7. doi:10.1016/j.dcn.2015.05.003  
718.   Hashimoto Teruo, Takeuchi Hikaru, Taki Yasuyuki, et al. Increased Posterior Hippocampal Volumes in Children with Lower Increase in Body Mass Index: A 3-Year Longitudinal MRI Study. Developmental Neuroscience. 2015; 37 (2): 153-160. doi:10.1159/000370064  
719.   Ehara Tatsuya, Kamei Yasutomi, Yuan Xunmei, et al. Ligand-Activated PPAR?-Dependent DNA Demethylation Regulates the Fatty Acid ?-Oxidation Genes in the Postnatal Liver. Diabetes. 2015; 64 (3): 775-784. doi:10.2337/db14-0158  
720.   Ehara Tatsuya, Kamei Yasutomi, Yuan Xunmei, et al. Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver. Diabetes. 2015; 64 (3): 775-784. doi:10.2337/db14-0158  
721.   Nishigori Hidekazu, Sasaki Michiho, Obara Taku, et al. Correlation Between the Great East Japan Earthquake and Postpartum Depression: A Study in Miyako, Iwate, Japan. Disaster medicine and public health preparedness. 2015; 9 (3): 307-12. doi:0.1017/dmp.2015.51  
722.   Lebowitz Adam, Tsai Athena Yi-Jung, Forester Brent P, et al. Possibilities for a Composite Approach: Summary of the Disaster Gerontology Panel at the International College of Geriatric Psychoneuropharmacology Annual Meeting (ICGP-2014). Disaster Medicine and Public Health Preparedness. 2015; 9 (5): 478-479. doi:10.1017/dmp.2015.87  
723.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. The Association Between Medical Treatment of Physical Diseases and Psychological Distress After the Great East Japan Earthquake: The Shichigahama Health Promotion Project. Disaster Medicine and Public Health Preparedness. 2015; 9 (4): 374-381. doi:10.1017/dmp.2015.52  
724.   Saito T, Honda M, Takahashi M, et al. Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid omega-hydroxylation. Drug Metab Pharmacokinet. 2015; 30 (1): 119-122. doi:10.1016/j.dmpk.2014.09.001  
725.   Ito H, Hozawa A, Yamashita H, et al. Employment status among non-retired cancer survivors in Japan. European Journal of Cancer Care. 2015; 24 (5): 718-723. doi:10.1111/ecc.12304  
726.   Okuda N, Miura K, Okayama A, et al. Fruit and vegetable intake and mortality from cardiovascular disease in Japan: a 24-year follow-up of the NIPPON DATA80 Study. European Journal of Clinical Nutrition. 2015; 69 (4): 482-488. doi:10.1038/ejcn.2014.276  
727.   Kimura Tomohiro, Nishizawa Keiko, Oguma Ayumi, et al. Secretin receptor involvement in prion-infected cells and animals. FEBS Letters. 2015; 589 (15): 2011-2018. doi:10.1016/j.febslet.2015.05.039  
728.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. The associations among the dopamine D2 receptor Taq1, emotional intelligence, creative potential measured by divergent thinking, and motivational state and these associations' sex differences. Frontiers in Psychology. 2015; 6 : . doi:10.3389/fpsyg.2015.00912  
729.   Tsujita Tadayuki, Baird Liam, Furusawa Yuki, et al. Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system. Genes to Cells. 2015; 20 (7): 563-577. doi:10.1111/gtc.12248  
730.   Yu Zhiqian, Ono Chiaki, Aiba Setsuya, et al. Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition. Glia. 2015; 63 (2): 257-270. doi:10.1002/glia.22749  
731.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Mean diffusivity of globus pallidus associated with verbal creativity measured by divergent thinking and creativity-related temperaments in young healthy adults. Human Brain Mapping. 2015; 36 (5): 1808-1827. doi:10.1002/hbm.22739  
732.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. The structure of the amygdala associates with human sexual permissiveness: Evidence from voxel-based morphometry. Human Brain Mapping. 2015; 36 (2): 440-448. doi:10.1002/hbm.22638  
733.   Hino-Fukuyo Naomi, Kikuchi Atsuo, Arai-Ichinoi Natsuko, et al. Genomic analysis identifies candidate pathogenic variants in 9 of 18 patients with unexplained West syndrome. Human Genetics. 2015; 134 (6): 649-658. doi:10.1007/s00439-015-1553-6  
734.   Yamaguchi-Kabata Yumi, Nariai Naoki, Kawai Yosuke, et al. iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing. Human Genome Variation. 2015; 2 (1): 15050. doi:10.1038/hgv.2015.50  
735.   Li Zheng, Allingham R. Rand, Nakano Masakazu, et al. A common variant near TGFBR3 is associated with primary open angle glaucoma. Human Molecular Genetics. 2015; 24 (13): 3880-3892. doi:10.1093/hmg/ddv128  
736.   Obara Taku, Ubeda Sergio Ramón Gutiérrez, Ohkubo Takayoshi, et al. Awareness of the Japanese Society of Hypertension Guidelines for the Management of Hypertension and their use in clinical practices: 2009 survey results. Hypertension Research. 2015; 38 (6): 400-404. doi:10.1038/hr.2015.21  
737.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Parity as a factor affecting the white-coat effect in pregnant women: the BOSHI study. Hypertension Research. 2015; 38 (11): 770-775. doi:10.1038/hr.2015.97  
738.   Hosaka Miki, Metoki Hirohito, Satoh Michihiro, et al. Randomized trial comparing the velocities of the antihypertensive effects on home blood pressure of candesartan and candesartan with hydrochlorothiazide. Hypertension Research. 2015; 38 (10): 701-707. doi:10.1038/hr.2015.64  
739.   Hosaka Miki, Asayama Kei, Staessen Jan A, et al. Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development. Hypertension Research. 2015; 38 (11): 776-782. doi:10.1038/hr.2015.63  
740.   Nagai Masato, Ohkubo Takayoshi, Murakami Yoshitaka, et al. Secular trends of the impact of overweight and obesity on hypertension in Japan, 1980–2010. Hypertension Research. 2015; 38 (11): 798-798. doi:10.1038/hr.2015.94  
741.   Hirayama Atsushi, Konta Tsuneo, Hozawa Atsushi, et al. Slight increase in urinary albumin excretion within the normal range predicts incident hypertension in a community-based Japanese population: the Takahata study. Hypertension Research. 2015; 38 (1): 56-60. doi:10.1038/hr.2014.117  
742.   Watanabe Masanari, Noma Hisashi, Kurai Jun, et al. Variation in the Effect of Particulate Matter on Pulmonary Function in Schoolchildren in Western Japan and Its Relation with Interleukin-8. International Journal of Environmental Research and Public Health. 2015; 12 (11): 14229-14243. doi:10.3390/ijerph121114229  
743.   Takahashi Kenta, Shiraishi Naru, Ishiko-Uzuka Risa, et al. Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young’s Modulus. International Journal of Molecular Sciences. 2015; 16 (12): 5779-5788. doi:10.3390/ijms16035779  
744.   Shimizu Ken, Nakaya Naoki, Saito-Nakaya Kumi, et al. Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors. Japanese Journal of Clinical Oncology. 2015; 45 (5): 456-463. doi:10.1093/jjco/hyv024  
745.   Hozawa Atsushi, Okamura Tomonori. Participants with Treated Hyperlipidemia may be More Health Conscious. Journal of Atherosclerosis and Thrombosis. 2015; 22 (10): 1025-1026. doi:10.5551/jat.ED021  
746.   Sugiyama Daisuke, Okamura Tomonori, Watanabe Makoto, et al. Risk of Hypercholesterolemia for Cardiovascular Disease and the Population Attributable Fraction in a 24-year Japanese Cohort Study. Journal of Atherosclerosis and Thrombosis. 2015; 22 (1): 95-107. doi:10.5551/jat.25908  
747.   Nakajima Tomomi, Kitagawa Kyoko, Ohhata Tatsuya, et al. Regulation of GATA-binding Protein 2 Levels via Ubiquitin-dependent Degradation by Fbw7. Journal of Biological Chemistry. 2015; 290 (16): 10368-10381. doi:10.1074/jbc.M114.613018  
748.   Suzuki Asami, Takai-Igarashi Takako, Nakaya Jun, Tanaka Hiroshi. Development of an Ontology for Periodontitis. Journal of Biomedical Semantics. 2015; 6 (1): 30. doi:10.1186/s13326-015-0028-y  
749.   Aoki-Kinoshita Kiyoko F, Kinjo Akira R, Morita Mizuki, et al. Implementation of linked data in the life sciences at BioHackathon 2011. Journal of Biomedical Semantics. 2015; 6 (1): 3. doi:10.1186/2041-1480-6-3  
750.   Kasai Takuma, Koshiba Seizo, Yokoyama Jun, Kigawa Takanori. Stable isotope labeling strategy based on coding theory. Journal of Biomolecular NMR. 2015; 63 (2): 213-221. doi:10.1007/s10858-015-9978-8  
751.   Okamura Ken, Ohe Rintaro, Abe Yuko, et al. Immunohistopathological analysis of frizzled-4-positive immature melanocytes from hair follicles of patients with Rhododenol-induced leukoderma. Journal of Dermatological Science. 2015; 80 (2): 156-158. doi:10.1016/j.jdermsci.2015.07.015  
752.   Takazawa Yuko, Ogawa Eisaku, Saito Rumiko, et al. Notch down-regulation in regenerated epidermis contributes to enhanced expression of interleukin-36α and suppression of keratinocyte differentiation during wound healing. Journal of Dermatological Science. 2015; 79 (1): 10-19. doi:10.1016/j.jdermsci.2015.04.003  
753.   Iijima Katsunori, Koike Tomoyuki, Abe Yasuhiko, et al. Time series analysis of gastric acid secretion over a 20-year period in normal Japanese men. Journal of Gastroenterology. 2015; 50 (8): 853-861. doi:10.1007/s00535-014-1031-2  
754.   Kaneko Mikiko, Ohashi Hirofumi, Takamura Tomoko, Kawame Hiroshi. Psychosocial Responses to being Identified as a Balanced Chromosomal Translocation Carrier: a Qualitative Investigation of Parents in Japan. Journal of Genetic Counseling. 2015; 24 (6): 922-930. doi:10.1007/s10897-015-9828-6  
755.   Sato Hiroko, Uchida Toshihiko, Toyota Kentaro, et al. Association of neonatal hyperbilirubinemia in breast-fed infants with UGT1A1 or SLCOs polymorphisms. Journal of Human Genetics. 2015; 60 (1): 35-40. doi:10.1038/jhg.2014.98  
756.   Kawai Yosuke, Mimori Takahiro, Kojima Kaname, et al. Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals. Journal of Human Genetics. 2015; 60 (10): 581-587. doi:10.1038/jhg.2015.68  
757.   Satoh Michihiro, Hosaka Miki, Asayama Kei, et al. Association between N-terminal pro B-type natriuretic peptide and day-to-day blood pressure and heart rate variability in a general population: the Ohasama study. Journal of Hypertension. 2015; 28 (2): 1. doi:10.1097/HJH.0000000000000570  
758.   Ishikuro Mami, Obara Taku, Metoki Hirohito, et al. Differences between clinic and home blood pressure measurements during pregnancy. Journal of Hypertension. 2015; 33 (7): 1492-1493. doi:10.1097/HJH.0000000000000608  
759.   Tanaka Hiroshi, Ogishima Soichi. Network biology approach to epithelial–mesenchymal transition in cancer metastasis: three stage theory. Journal of Molecular Cell Biology. 2015; 7 (3): 253-266. doi:10.1093/jmcb/mjv035  
760.   Takeuchi H., Taki Y., Hashizume H., et al. The Impact of Parent-Child Interaction on Brain Structures: Cross-sectional and Longitudinal Analyses. Journal of Neuroscience. 2015; 35 (5): 2233-2245. doi:10.1523/JNEUROSCI.0598-14.2015  
761.   Tadakawa Mari, Sugawara Junichi, Saito Masatoshi, et al. Fertility and pregnancy outcomes following B-Lynch sutures for post-partum hemorrhage. Journal of Obstetrics and Gynaecology Research. 2015; 41 (4): 559-564. doi:10.1111/jog.12590  
762.   Yamazaki Isao, Kimura Fumiko, Nakagawa Kiyotaka, et al. Heterogeneity of the Fatty Acid Composition of Japanese Placentae for Determining the Perinatal Fatty Acid Status: a Methodological Study. Journal of Oleo Science. 2015; 64 (8): 905-914. doi:10.5650/jos.ess15071  
763.   Sone Toshimasa, Nakaya Naoki, Iokawa Kazuaki, et al. Prediction of Upper Limb Recovery in the Acute Phase of Cerebrovascular Disease: Evaluation of “Functional Hand” Using the Manual Function Test. Journal of Stroke and Cerebrovascular Diseases. 2015; 24 (4): 815-822. doi:10.1016/j.jstrokecerebrovasdis.2014.11.018  
764.   Tochio Naoya, Umehara Takashi, Nakabayashi Kazuhiko, et al. Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT. Journal of Structural and Functional Genomics. 2015; 16 (2): 55-65. doi:10.1007/s10969-015-9196-3  
765.   Takeuchi Yoichi, Mishima Eikan, Shima Hisato, et al. Exonic Mutations in the SLC12A3 Gene Cause Exon Skipping and Premature Termination in Gitelman Syndrome. Journal of the American Society of Nephrology. 2015; 26 (2): 271-279. doi:10.1681/ASN.2013091013  
766.   Mishima Eikan, Fukuda Shinji, Shima Hisato, et al. Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD. Journal of the American Society of Nephrology : JASN. 2015; 26 (8): 1787-94. doi:10.1681/ASN.2014060530  
767.   Nakamura Tomohiro, Douke Hideyuki. A SEQUENTIAL MULTIPLE COMPARISON PROCEDURE FOR DETECTING A LOWEST DOSE HAVING INTERACTION IN A DOSE-RESPONSE TEST. Journal of the Japanese Society of Computational Statistics. 2015; 28 (1): 1-14. doi:10.5183/jjscs.1406001_212  
768.   河合 洋介, 三森 隆広, 小島 要, et al. ジャポニカアレイの設計と全ゲノムインピュテーションによる活用. Medical Science Digest. 2015; 41 (5): 34-37. http://hokuryukan-ns.co.jp/magazines/archives/2015/04/medical_science_135.html  
769.   Norimatsu Yuka, Kawashima Junko, Takano-Yamamoto Teruko, Takahashi Nobuhiro. Nitrogenous compounds stimulate glucose-derived acid production by oral Streptococcus and Actinomyces. Microbiology and Immunology. 2015; 59 (9): 501-506. doi:10.1111/1348-0421.12283  
770.   Tsukazaki Hikaru, Yaguchi Shigenori, Sato Shusei, et al. Development of transcriptome shotgun assembly-derived markers in bunching onion (Allium fistulosum). Molecular Breeding. 2015; 35 (1): 55. doi:10.1007/s11032-015-0265-x  
771.   Sekiguchi A, Kotozaki Y, Sugiura M, et al. Resilience after 3/11: structural brain changes 1 year after the Japanese earthquake. Molecular Psychiatry. 2015; 20 (5): 553-554. doi:10.1038/mp.2014.28  
772.   Kitatani Kazuyuki, Taniguchi Makoto, Okazaki Toshiro. Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies. Molecules and Cells. 2015; 38 (6): 482-495. doi:10.14348/molcells.2015.0118  
773.   Asai Teigo, Tsukada Kento, Ise Satomi, et al. Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides. Nature Chemistry. 2015; 7 (9): 737-743. doi:10.1038/nchem.2308  
774.   Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature Communications. 2015; 6 (1): 8018. doi:10.1038/ncomms9018  
775.   Nishikawa Keizo, Iwamoto Yoriko, Kobayashi Yasuhiro, et al. DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway. Nature Medicine. 2015; 21 (3): 281-287. doi:10.1038/nm.3774  
776.   Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, et al. Cognitive and neural correlates of the 5-repeat allele of the dopamine D4 receptor gene in a population lacking the 7-repeat allele. NeuroImage. 2015; 110 : 124-135. doi:10.1016/j.neuroimage.2015.01.053  
777.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Comprehensive neural networks for guilty feelings in young adults. NeuroImage. 2015; 105 : 248-256. doi:10.1016/j.neuroimage.2014.11.004  
778.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Degree centrality and fractional amplitude of low-frequency oscillations associated with Stroop interference. NeuroImage. 2015; 119 : 197-209. doi:10.1016/j.neuroimage.2015.06.058  
779.   Hashimoto Teruo, Takeuchi Hikaru, Taki Yasuyuki, et al. Neuroanatomical correlates of the sense of control: Gray and white matter volumes associated with an internal locus of control. NeuroImage. 2015; 119 : 146-151. doi:10.1016/j.neuroimage.2015.06.061  
780.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Regional gray matter density is associated with morningness–eveningness: Evidence from voxel-based morphometry. NeuroImage. 2015; 117 : 294-304. doi:10.1016/j.neuroimage.2015.05.037  
781.   Okamura Yasunobu, Aoki Yuichi, Obayashi Takeshi, et al. COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems. Nucleic Acids Research. 2015; 43 (D1): D82-D86. doi:10.1093/nar/gku1163  
782.   Huang C, Tomata Y, Kakizaki M, et al. High circulating adiponectin levels predict decreased muscle strength among older adults aged 70 years and over: A prospective cohort study. Nutrition, Metabolism and Cardiovascular Diseases. 2015; 25 (6): 594-601. doi:10.1016/j.numecd.2015.03.010  
783.   Kitatani K, Usui T, Sriraman S K, et al. Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid. Oncogene. 2015; 35 (21): 2801-2812. doi:10.1038/onc.2015.330  
784.   Obara, Abe Shinya, Sato Michihiro, et al. Awareness regarding clinical application of pharmacogenetics among Japanese pharmacists. Pharmacogenomics and Personalized Medicine. 2015; 8 : 35. doi:10.2147/PGPM.S71813  
785.   Shimanuki Miwa, Abe Yuko, Tamiya Gen, et al. Positive selection with diversity in oculocutaneous albinisms type 2 gene ( OCA2 ) among Japanese. Pigment Cell & Melanoma Research. 2015; 28 (2): 233-235. doi:10.1111/pcmr.12337  
786.   Funaki Ayuta, Waki Toshiyuki, Noguchi Akio, et al. Identification of a Highly Specific Isoflavone 7- O -glucosyltransferase in the soybean ( Glycine max (L.) Merr.). Plant and Cell Physiology. 2015; 56 (8): 1512-1520. doi:10.1093/pcp/pcv072  
787.   Kitatani Kazuyuki, Wada Masayuki, Perry David, et al. Activation of p38 Mitogen-Activated Protein Kinase in Gaucher’s Disease. PLOS ONE. 2015; 10 (8): e0136633. doi:10.1371/journal.pone.0136633  
788.   Hasegawa Jun, Hidaka Hiroshi, Kuriyama Shinichi, et al. Change in and Long-Term Investigation of Neuro-Otologic Disorders in Disaster-Stricken Fukushima Prefecture: Retrospective Cohort Study before and after the Great East Japan Earthquake. PLOS ONE. 2015; 10 (4): e0122631. doi:10.1371/journal.pone.0122631  
789.   Ito Daisuke, Cao Pengyu, Kakihana Takaaki, et al. Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats. PLOS ONE. 2015; 10 (9): e0138037. doi:10.1371/journal.pone.0138037  
790.   Okamura Yasunobu, Obayashi Takeshi, Kinoshita Kengo. Comparison of Gene Coexpression Profiles and Construction of Conserved Gene Networks to Find Functional Modules. PLOS ONE. 2015; 10 (7): e0132039. doi:10.1371/journal.pone.0132039  
791.   Mishima Eikan, Jinno Daisuke, Akiyama Yasutoshi, et al. Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides. PLOS ONE. 2015; 10 (11): e0143756. doi:10.1371/journal.pone.0143756  
792.   Sato Yukuto, Yamagishi Junya, Yamashita Riu, et al. Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals. PLOS ONE. 2015; 10 (6): e0131607. doi:10.1371/journal.pone.0131607  
793.   Tayama Jun, Nakaya Naoki, Hamaguchi Toyohiro, et al. Maladjustment to Academic Life and Employment Anxiety in University Students with Irritable Bowel Syndrome. PLOS ONE. 2015; 10 (6): e0129345. doi:10.1371/journal.pone.0129345  
794.   Sato Chiho, Sekiguchi Atsushi, Kawai Masaaki, et al. Postoperative Structural Brain Changes and Cognitive Dysfunction in Patients with Breast Cancer. PLOS ONE. 2015; 10 (11): e0140655. doi:10.1371/journal.pone.0140655  
795.   Yokoyama Ryoichi, Nozawa Takayuki, Takeuchi Hikaru, et al. Regional Gray Matter Density Associated with Cognitive Reflectivity–Impulsivity: Evidence from Voxel-Based Morphometry. PLOS ONE. 2015; 10 (3): e0122666. doi:10.1371/journal.pone.0122666  
796.   Magistro Daniele, Takeuchi Hikaru, Nejad Keyvan Kashkouli, et al. The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. PLOS ONE. 2015; 10 (9): e0136386. doi:10.1371/journal.pone.0136386  
797.   Keleku-Lukwete Nadine, Suzuki Mikiko, Otsuki Akihito, et al. Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation. Proceedings of the National Academy of Sciences. 2015; 112 (39): 12169-12174. doi:10.1073/pnas.1509158112  
798.   Inoue Jun, Sato Yukuto, Sinclair Robert, et al. Rapid genome reshaping by multiple-gene loss after whole-genome duplication in teleost fish suggested by mathematical modeling. Proceedings of the National Academy of Sciences. 2015; 112 (48): 14918-14923. doi:10.1073/pnas.1507669112  
799.   Tanji F., Kakizaki M., Sugawara Y., et al. Personality and suicide risk: the impact of economic crisis in Japan. Psychological Medicine. 2015; 45 (03): 559-573. doi:10.1017/S0033291714001688  
800.   Miya M., Sato Y., Fukunaga T., et al. MiFish, a set of universal PCR primers for metabarcoding environmental DNA from fishes: detection of more than 230 subtropical marine species. Royal Society Open Science. 2015; 2 (7): 150088. doi:10.1098/rsos.150088  
801.   Arner E., Daub C. O., Vitting-Seerup K., et al. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science. 2015; 347 (6225): 1010-1014. doi:10.1126/science.1259418  
802.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Amygdala and cingulate structure is associated with stereotype on sex-role. Scientific Reports. 2015; 5 (1): 14220. doi:10.1038/srep14220  
803.   Okamura-Oho Yuko, Shimokawa Kazuro, Nishimura Masaomi, et al. Broad Integration of Expression Maps and Co-Expression Networks Compassing Novel Gene Functions in the Brain. Scientific Reports. 2015; 4 (1): 6969. doi:10.1038/srep06969  
804.   Koizumi Taichi, Terada Tohru, Nakajima Ken-ichiro, et al. Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor. Scientific Reports. 2015; 5 (1): 12947. doi:10.1038/srep12947  
805.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. White matter structures associated with loneliness in young adults. Scientific Reports. 2015; 5 (1): 17001. doi:10.1038/srep17001  
806.   Hori-Tanaka Yasuha, Yura Kei, Takai-Igarashi Takako, Tanaka Hiroshi. Structural classification of steroid-binding sites on proteins by coarse-grained atomic environment and its correlation with their biological function. Steroids. 2015; 96 : 81-88. doi:10.1016/j.steroids.2015.01.015  
807.   Ogishima Soichi, Takai Takako, Shimokawa Kazuro, et al. Integrated Database And Knowledge Base For Genomic Prospective Cohort Study In Tohoku Medical Megabank Toward Personalized Prevention And Medicine. Studies in health technology and informatics. 2015; 216 : 1057. doi:10.3233/978-1-61499-564-7-1057  
808.   Okamura Ken, Oiso Naoki, Tamiya Gen, et al. Waardenburg syndrome type IIE in a Japanese patient caused by a novel missense mutation in the SOX10 gene. The Journal of Dermatology. 2015; 42 (12): 1211-1212. doi:10.1111/1346-8138.13095  
809.   Watanabe Masanari, Kurai Jun, Minato Sayaka, et al. Difference in interleukin-8 transcriptional activity induced in THP-G8 cells by particulate matter collected in winter and summer in western Japan. The Journal of Medical Investigation. 2015; 62 (3.4): 145-148. doi:10.2152/jmi.62.145  
810.   Tsubota-Utsugi Megumi, Kikuya M., Satoh M., et al. Living situations associated with poor dietary intake among healthy japanese elderly: The ohasama study. The journal of nutrition, health & aging. 2015; 19 (4): 375-382. doi:10.1007/s12603-015-0456-5  
811.   Miyashita Masako, Kikuya Masahiro, Yamanaka Chizuru, et al. Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. The Tohoku Journal of Experimental Medicine. 2015; 237 (4): 297-305. doi:10.1620/tjem.237.297  
812.   Saitoh Hiroki, Koizumi Nobuo, Seto Junji, et al. Leptospirosis in the Tohoku Region: Re-emerging Infectious Disease. The Tohoku Journal of Experimental Medicine. 2015; 236 (1): 33-37. doi:10.1620/tjem.236.33  
813.   Suzuki Takehiro, Yamaguchi Hiroaki, Kikusato Motoi, et al. Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases. The Tohoku Journal of Experimental Medicine. 2015; 236 (3): 225-232. doi:10.1620/tjem.236.225  
814.   Kikuya Masahiro, Miyashita Masako, Yamanaka Chizuru, et al. Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2015; 236 (2): 123-130. doi:10.1620/tjem.236.123  
815.   Dendo Mami, Maeda Hiroshi, Yamagata Youhei, et al. Synergistic Effect of Neutral Protease and Clostripain on Rat Pancreatic Islet Isolation. Transplantation. 2015; 99 (7): 1349-55. doi:10.1097/TP.0000000000000662  
816.   西本 光男, 湊 敬道, 高橋 聡太, et al. 経腟穿刺採卵から2か月後に卵巣膿瘍となった子宮内膜症合併不妊の1例. 岩手県立病院医学会雑誌. 2015; 55 (1): 35-39. http://jglobal.jst.go.jp/public/201502208333918994  
817.   佐藤 ゆき, 加藤 忠明, 顧 艶紅. 4歳児の母親の不安抑うつ症状と周囲の育児サポート状況との関連. 小児保健研究. 2015; 74 (4): 506-512. http://post.neet-system.com/naid/40020545322  
818.   高橋 孝子, 笠原 賀子, 佐藤 ゆき. 保育所給食のある日とない日の幼児の栄養素摂取量の比較. 神戸女子大学家政学部紀要. 2015; 48 : 39-46. http://www.yg.kobe-wu.ac.jp/doc/wu/kasei03/HTML/index31.html  
819.   小林 朋子, 川目 裕. 【こどもの病気 遺伝について聞かれたら】 頭蓋骨縫合早期癒合症候群. 診断と治療社. 2015; 4 : 174-176. http://www.shindan.co.jp/books/index.php?menu=10&cd=205900&kbn=1  
820.   中村 智洋, 八木 圭太, 山本 義郎, 道家 暎幸. 用量反応試験における交互作用検出のための逐次型多重比較法について. 日本統計学会和文誌. 2015; 40 (2): 315-339. http://ci.nii.ac.jp/naid/110009828419  
821.   濱田 裕貴, 菅原 準一. 体外受精妊娠の周産期母体管理. 臨床婦人科産科. 2015; 69 (8): 764-772. https://www.igaku-shoin.co.jp/journalDetail.do?journal=36163  
822.   Nouchi Rui, Taki Yasuyuki, Takeuchi Hikaru, et al. Four weeks of combination exercise training improved executive functions, episodic memory, and processing speed in healthy elderly people: evidence from a randomized controlled trial. Age (Dordrecht, Netherlands). 2014; 36 (2): 787-799. doi:10.1007/s11357-013-9588-x  
823.   Katsuoka Fumiki, Yokozawa Junji, Tsuda Kaoru, et al. An efficient quantitation method of next-generation sequencing libraries by using MiSeq sequencer. Analytical Biochemistry. 2014; 466 (466C): 27-29. doi:10.1016/j.ab.2014.08.015  
824.   Fujiwara Tohru, Fukuhara Noriko, Funayama Ryo, et al. Identification of acquired mutations by whole-genome sequencing in GATA-2 deficiency evolving into myelodysplasia and acute leukemia. Annals of Hematology. 2014; 93 (9): 1515-1522. doi:10.1007/s00277-014-2090-4  
825.   Nishigori Hidekazu, Sugawara Junichi, Obara Taku, et al. Surveys of postpartum depression in Miyagi, Japan, after the Great East Japan Earthquake. Archives of Women's Mental Health. 2014; 17 (6): 579-581. doi:10.1007/s00737-014-0459-y  
826.   Hase Takeshi, Kikuchi Kaito, Ghosh Samik, et al. Identification of drug-target modules in the human protein–protein interaction network. Artificial Life and Robotics. 2014; 19 (4): 406-413. doi:10.1007/s10015-014-0178-5  
827.   Miyagawa Naoko, Miura Katsuyuki, Okuda Nagako, et al. Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in Japanese: a 24-year follow-up of NIPPON DATA80. Atherosclerosis. 2014; 232 (2): 384-9. doi:10.1016/j.atherosclerosis.2013.11.073  
828.   Sekiguchi Atsushi, Kotozaki Yuka, Sugiura Motoaki, et al. Long-Term Effects of Postearthquake Distress on Brain Microstructural Changes. BioMed Research International. 2014; 2014 : 1-7. doi:10.1155/2014/180468  
829.   Saigo Tatsuo, Tayama Jun, Hamaguchi Toyohiro, et al. Gastrointestinal specific anxiety in irritable bowel syndrome: validation of the Japanese version of the visceral sensitivity index for university students. BioPsychoSocial Medicine. 2014; 8 (1): 10. doi:10.1186/1751-0759-8-10  
830.   Hasegawa Takanori, Nagasaki Masao, Yamaguchi Rui, et al. An efficient method of exploring simulation models by assimilating literature and biological observational data. Biosystems. 2014; 121 : 54-66. doi:10.1016/j.biosystems.2014.06.001  
831.   Li Chen, Nagasaki Masao, Ikeda Emi, et al. CSML2SBML: A novel tool for converting quantitative biological pathway models from CSML into SBML. Biosystems. 2014; 121 : 22-28. doi:10.1016/j.biosystems.2014.05.004  
832.   Kasahara Kota, Kinoshita Kengo. GIANT: pattern analysis of molecular interactions in 3D structures of protein–small ligand complexes. BMC Bioinformatics. 2014; 15 (1): 12. doi:10.1186/1471-2105-15-12  
833.   Sato Yukuto, Kojima Kaname, Nariai Naoki, et al. SUGAR: graphical user interface-based data refiner for high-throughput DNA sequencing. BMC Genomics. 2014; 15 (1): 664. doi:10.1186/1471-2164-15-664  
834.   Yamagishi Junya, Wakaguri Hiroyuki, Yokoyama Naoaki, et al. The Babesia bovis gene and promoter model: an update from full-length EST analysis. BMC Genomics. 2014; 15 (1): 678. doi:10.1186/1471-2164-15-678  
835.   Nariai Naoki, Kojima Kaname, Mimori Takahiro, et al. TIGAR2: sensitive and accurate estimation of transcript isoform expression with longer RNA-Seq reads. BMC Genomics. 2014; 15 (S10): S5. doi:10.1186/1471-2164-15-S10-S5  
836.   Motoike Ikuko N, Matsumoto Mitsuyo, Danjoh Inaho, et al. Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population. BMC Genomics. 2014; 15 (1): 673. doi:10.1186/1471-2164-15-673  
837.   Takezawa Yasuko, Kato Kazuto, Oota Hiroki, et al. Human genetic research, race, ethnicity and the labeling of populations: recommendations based on an interdisciplinary workshop in Japan. BMC Medical Ethics. 2014; 15 (1): 33. doi:10.1186/1472-6939-15-33  
838.   Kotozaki Yuka, Takeuchi Hikaru, Sekiguchi Atsushi, et al. Biofeedback-based training for stress management in daily hassles: an intervention study. Brain and Behavior. 2014; 4 (4): 566-579. doi:10.1002/brb3.241  
839.   Asano Michiko, Taki Yasuyuki, Hashizume Hiroshi, et al. Correlations between brain structures and study time at home in healthy children: a longitudinal analysis. Brain and Behavior. 2014; 4 (6): 801-811. doi:10.1002/brb3.278  
840.   Yamazaki Hiromi, Suzuki Mikiko, Otsuki Akihito, et al. A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21;q26) by Activating EVI1 Expression. Cancer Cell. 2014; 25 (4): 415-427. doi:10.1016/j.ccr.2014.02.008  
841.   関口 敦. PTSDにおける扁桃体. Clinical Neuroscience. 2014; 32(6) : 686-689. http://www.chugaiigaku.jp/item/detail.php?id=1538  
842.   Mizoue Shiro, Nakano Tadashi, Fuse Nobuo, et al. Travoprost with sofZia® preservative system lowered intraocular pressure of Japanese normal tension glaucoma with minimal side effects. Clinical Ophthalmology. 2014; 8 : 347. doi:10.2147/OPTH.S57640  
843.   Iwasaki Y., Suganami T., Hachiya R., et al. Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages. Diabetes. 2014; 63 (1): 152-161. doi:10.2337/db13-0757  
844.   Yagishita Yoko, Fukutomi Toshiaki, Sugawara Akira, et al. Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice. Diabetes. 2014; 63 (2): 605-618. doi:10.2337/db13-0909  
845.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Creativity measured by divergent thinking is associated with two axes of autistic characteristics. Frontiers in psychology. 2014; 5 : 921. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4137690&tool=pmcentrez&rendertype=abstract  
846.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Working memory training improves emotional states of healthy individuals. Frontiers in Systems Neuroscience. 2014; 8 : 200. doi:10.3389/fnsys.2014.00200  
847.   Hirotsu Yosuke, Higashi Chika, Fukutomi Toshiaki, et al. Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice. Genes to Cells. 2014; 19 (8): 650-665. doi:10.1111/gtc.12165  
848.   Yamagishi Junya, Natori Anna, Tolba Mohammed E.M., et al. Interactive transcriptome analysis of malaria patients and infecting Plasmodium falciparum. Genome Research. 2014; 24 (9): 1433-1444. doi:10.1101/gr.158980.113  
849.   Hashizume Hiroshi, Taki Yasuyuki, Sassa Yuko, et al. Developmental changes in brain activation involved in the production of novel speech sounds in children. Human Brain Mapping. 2014; 35 (8): 4079-4089. doi:10.1002/hbm.22460  
850.   Shi Lihong, Lin Y.-H., Sierant M. C., et al. Developmental transcriptome analysis of human erythropoiesis. Human Molecular Genetics. 2014; 23 (17): 4528-4542. doi:10.1093/hmg/ddu167  
851.   Matsumoto A., Satoh M., Kikuya M., et al. Day-to-Day Variability in Home Blood Pressure Is Associated With Cognitive Decline: The Ohasama Study. Hypertension. 2014; 63 (6): 1333-1338. doi:10.1161/HYPERTENSIONAHA.113.01819  
852.   Stergiou George S, Asayama Kei, Thijs Lutgarde, et al. Prognosis of white-coat and masked hypertension: International Database of HOme blood pressure in relation to Cardiovascular Outcome. Hypertension. 2014; 63 (4): 675-82. doi:10.1161/HYPERTENSIONAHA.113.02741  
853.   Nomura Kyoko, Asayama Kei, Thijs Lutgarde, et al. Thresholds for Conventional and Home Blood Pressure by Sex and Age in 5018 Participants From 5 Populations. Hypertension. 2014; 64 (4): 695-701. doi:10.1161/HYPERTENSIONAHA.114.03839  
854.   Aparicio Lucas S, Thijs Lutgarde, Asayama Kei, et al. Reference frame for home pulse pressure based on cardiovascular risk in 6470 subjects from 5 populations. Hypertension Research. 2014; 37 (7): 672-678. doi:10.1038/hr.2014.45  
855.   Watanabe Masanari, Kurai Jun, Tomita Katsuyuki, et al. Effects on asthma and induction of interleukin-8 caused by Asian dust particles collected in western Japan. Journal of Asthma. 2014; 51 (6): 595-602. doi:10.3109/02770903.2014.903965  
856.   Perry David M, Newcomb Benjamin, Adada Mohamad, et al. Defining a Role for Acid Sphingomyelinase in the p38/Interleukin-6 Pathway. Journal of Biological Chemistry. 2014; 289 (32): 22401-22412. doi:10.1074/jbc.M114.589648  
857.   Katayama Toshiaki, Wilkinson Mark D, Aoki-Kinoshita Kiyoko F, et al. BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains. Journal of Biomedical Semantics. 2014; 5 (1): 5. doi:10.1186/2041-1480-5-5  
858.   Nakaya Naoki. Effect of Psychosocial Factors on Cancer Risk and Survival. Journal of Epidemiology. 2014; 24 (1): 1-6. doi:10.2188/jea.JE20130124  
859.   Okudaira Michiyo, Inoue Asuka, Shuto Akira, et al. Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS. Journal of Lipid Research. 2014; 55 (10): 2178-2192. doi:10.1194/jlr.D048439  
860.   Tatewaki Yasuko, Higano Shuichi, Taki Yasuyuki, et al. Regional Reliability of Quantitative Signal Targeting with Alternating Radiofrequency (STAR) Labeling of Arterial Regions (QUASAR). Journal of Neuroimaging. 2014; 24 (6): 554-561. doi:10.1111/jon.12076  
861.   Kunikata Hiroshi, Aizawa Naoko, Fuse Nobuo, et al. 25-Gauge Microincision Vitrectomy to Treat Vitreoretinal Disease in Glaucomatous Eyes after Trabeculectomy. Journal of Ophthalmology. 2014; 2014 : 1-8. doi:10.1155/2014/306814  
862.   Imai Eri, Tsubota-Utsugi Megumi, Kikuya Masahiro, et al. Animal Protein Intake Is Associated with Higher-Level Functional Capacity in Elderly Adults: The Ohasama Study. Journal of the American Geriatrics Society. 2014; 62 (3): 426-434. doi:10.1111/jgs.12690  
863.   Mishima Eikan, Inoue Chisako, Saigusa Daisuke, et al. Conformational change in transfer RNA is an early indicator of acute cellular damage. Journal of the American Society of Nephrology : JASN. 2014; 25 (10): 2316-26. doi:10.1681/ASN.2013091001  
864.   Kuragano Takahiro, Matsumura Osamu, Matsuda Akihiko, et al. Association between hemoglobin variability, serum ferritin levels, and adverse events/mortality in maintenance hemodialysis patients. Kidney International. 2014; 86 (4): 845-854. doi:10.1038/ki.2014.114  
865.   境田 正樹. 東北メディカル・メガバンク計画における法的・倫理的課題. Law&Technology. 2014; 62 : 31-40. http://ci.nii.ac.jp/naid/40019922651  
866.   Kojima Kaname, Nariai Naoki, Mimori Takahiro, et al. HapMonster: A Statistically Unified Approach for Variant Calling and Haplotyping Based on Phase-Informative Reads. Lecture Notes in Computer Science. 2014; 8542 : 107-118. doi:10.1007/978-3-319-07953-0_9  
867.   Ohtsuki Tomohiko, Nariai Naoki, Kojima Kaname, et al. SVEM: A Structural Variant Estimation Method Using Multi-mapped Reads on Breakpoints. Lecture Notes in Computer Science. 2014; 8542 : 208-219. doi:10.1007/978-3-319-07953-0_17  
868.   Saigusa Daisuke, Okudaira Michiyo, Wang Jiao, et al. Simultaneous Quantification of Sphingolipids in Small Quantities of Liver by LC-MS/MS. Mass Spectrometry. 2014; 3 (Special_Issue_3): S0046-S0046. doi:10.5702/massspectrometry.S0046  
869.   Suzuki Mikiko, Yamamoto Masayuki, Engel James Douglas. Fetal Globin Gene Repressors as Drug Targets for Molecular Therapies To Treat the -Globinopathies. Molecular and Cellular Biology. 2014; 34 (19): 3560-3569. doi:10.1128/MCB.00714-14  
870.   Cui S., Tanabe O., Lim K.-C., et al. PGC-1 Coactivator Activity Is Required for Murine Erythropoiesis. Molecular and Cellular Biology. 2014; 34 (11): 1956-1965. doi:10.1128/MCB.00247-14  
871.   Felizola Saulo J.A., Nakamura Yasuhiro, Satoh Fumitoshi, et al. Glutamate receptors and the regulation of steroidogenesis in the human adrenal gland: The metabotropic pathway. Molecular and Cellular Endocrinology. 2014; 382 (1): 170-177. doi:10.1016/j.mce.2013.09.025  
872.   FANTOM Consortium and the RIKEN PMI and CLST (DGT) The FANTOM Consortium and the RIKEN PMI and CLST, Forrest Alistair R R, Kawaji Hideya, et al. A promoter-level mammalian expression atlas. Nature. 2014; 507 (7493): 462-70. doi:10.1038/nature13182  
873.   Takehana Yusuke, Matsuda Masaru, Myosho Taijun, et al. Co-option of Sox3 as the male-determining factor on the Y chromosome in the fish Oryzias dancena. Nature Communications. 2014; 5 (1): 4157. doi:10.1038/ncomms5157  
874.   Kashkouli Nejad Keyvan, Sugiura Motoaki, Thyreau Benjamin, et al. Spinal fMRI of Interoceptive Attention/Awareness in Experts and Novices. Neural Plasticity. 2014; 2014 : 1-7. doi:10.1155/2014/679509  
875.   Takeuchi Hikaru, Taki Yasuyuki, Nouchi Rui, et al. Association between resting-state functional connectivity and empathizing/systemizing. NeuroImage. 2014; 99 : 312-322. doi:10.1016/j.neuroimage.2014.05.031  
876.   Sumiyoshi Akira, Taki Yasuyuki, Nonaka Hiroi, et al. Regional gray matter volume increases following 7days of voluntary wheel running exercise: A longitudinal VBM study in rats. NeuroImage. 2014; 98 : 82-90. doi:10.1016/j.neuroimage.2014.04.075  
877.   Yokoyama Ryoichi, Nozawa Takayuki, Takeuchi Hikaru, et al. Association between gray matter volume in the caudate nucleus and financial extravagance: Findings from voxel-based morphometry. Neuroscience Letters. 2014; 563 : 28-32. doi:10.1016/j.neulet.2014.01.026  
878.   Asano Kohei, Taki Yasuyuki, Hashizume Hiroshi, et al. Healthy children show gender differences in correlations between nonverbal cognitive ability and brain activation during visual perception. Neuroscience Letters. 2014; 577 : 66-71. doi:10.1016/j.neulet.2014.06.015  
879.   Suzuki A., Wakaguri H., Yamashita R., et al. DBTSS as an integrative platform for transcriptome, epigenome and genome sequence variation data. Nucleic Acids Research. 2014; 43 (D1): D87-D91. doi:10.1093/nar/gku1080  
880.   Obayashi Takeshi, Okamura Yasunobu, Ito Satoshi, et al. ATTED-II in 2014: Evaluation of Gene Coexpression in Agriculturally Important Plants. Plant and Cell Physiology. 2014; 55 (1): e6-e6. doi:10.1093/pcp/pct178  
881.   Noguchi Akio, Horikawa Manabu, Murata Jun, et al. Mode-of-action and evolution of methylenedioxy bridge forming P450s in plant specialized metabolism. Plant Biotechnology. 2014; 31 (5): 493-503. doi:10.5511/plantbiotechnology.14.0828a  
882.   Shi Lihong, Sierant M. C., Gurdziel Katherine, et al. Biased, Non-equivalent Gene-Proximal and -Distal Binding Motifs of Orphan Nuclear Receptor TR4 in Primary Human Erythroid Cells. PLoS Genetics. 2014; 10 (5): e1004339. doi:10.1371/journal.pgen.1004339  
883.   Asayama Kei, Thijs Lutgarde, Brguljan-Hitij Jana, et al. Risk Stratification by Self-Measured Home Blood Pressure across Categories of Conventional Blood Pressure: A Participant-Level Meta-Analysis. PLoS Medicine. 2014; 11 (1): e1001591. doi:10.1371/journal.pmed.1001591  
884.   Ono Chiaki, Yu Zhiqian, Kasahara Yoshiyuki, et al. Fluorescently Activated Cell Sorting Followed by Microarray Profiling of Helper T Cell Subtypes from Human Peripheral Blood. PLoS ONE. 2014; 9 (11): e111405. doi:10.1371/journal.pone.0111405  
885.   Tsuchiya Masa, Hashimoto Midori, Takenaka Yoshiko, et al. Global Genetic Response in a Cancer Cell: Self-Organized Coherent Expression Dynamics. PLoS ONE. 2014; 9 (5): e97411. doi:10.1371/journal.pone.0097411  
886.   Hasegawa Takanori, Yamaguchi Rui, Nagasaki Masao, et al. Inference of Gene Regulatory Networks Incorporating Multi-Source Biological Knowledge via a State Space Model with L1 Regularization. PLoS ONE. 2014; 9 (8): e105942. doi:10.1371/journal.pone.0105942  
887.   Hatazawa Yukino, Tadaishi Miki, Nagaike Yuta, et al. PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle. PLoS ONE. 2014; 9 (3): e91006. doi:10.1371/journal.pone.0091006  
888.   Suenaga Kaori, Kitahara Shuji, Suzuki Yasuhiro, et al. Role of the Vasohibin Family in the Regulation of Fetoplacental Vascularization and Syncytiotrophoblast Formation. PLoS ONE. 2014; 9 (9): e104728. doi:10.1371/journal.pone.0104728  
889.   Atomi Tomoaki, Noriuchi Madoka, Oba Kentaro, et al. Self-Recognition of One's Own Fall Recruits the Genuine Bodily Crisis-Related Brain Activity. PLoS ONE. 2014; 9 (12): e115303. doi:10.1371/journal.pone.0115303  
890.   Sekiguchi Atsushi, Sugiura Motoaki, Taki Yasuyuki, et al. White Matter Microstructural Changes as Vulnerability Factors and Acquired Signs of Post-Earthquake Distress. PLoS ONE. 2014; 9 (1): e83967. doi:10.1371/journal.pone.0083967  
891.   Yamanouchi Satoshi, Ishii Tadashi, Morino Kazuma, et al. Streamlining of Medical Relief to Areas Affected by the Great East Japan Earthquake with the “Area-based/Line-linking Support System”. Prehospital and Disaster Medicine. 2014; 29 (6): 614-622. doi:10.1017/S1049023X14001095  
892.   Morihara T, Hayashi N, Yokokoji M, et al. Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-beta accumulation modifier. Proc Natl Acad Sci U S A. 2014; 111 (7): 2638-2643. doi:10.1073/pnas.1307345111  
893.   Nakagawa Seishu, Sugiura Motoaki, Sekiguchi Atsushi, et al. Fatigue and relating to others 3 months after the 2011 Great East Japan Earthquake. Psychiatry research. 2014; 218 (3): 324-8. http://www.ncbi.nlm.nih.gov/pubmed/24844979  
894.   Moriya Yuki, Kasahara Yoshiyuki, Hall F. Scott, et al. Sex differences in the effects of adolescent social deprivation on alcohol consumption in μ-opioid receptor knockout mice. Psychopharmacology. 2014; 232 (8): 1471-1482. doi:10.1007/s00213-014-3784-y  
895.   Mullen William, Saigusa Daisuke, Abe Takaaki, et al. Proteomics and Metabolomics as Tools to Unravel Novel Culprits and Mechanisms of Uremic Toxicity: Instrument or Hype?. Seminars in Nephrology. 2014; 34 (2): 180-190. doi:10.1016/j.semnephrol.2014.02.009  
896.   Sugiura Motoaki, Yomogida Yukihito, Mano Yoko, et al. From social-signal detection to higher social cognition: an fMRI approach. Social Cognitive and Affective Neuroscience. 2014; 9 (9): 1303-1309. doi:10.1093/scan/nst119  
897.   Ueki Masao. On the choice of degrees of freedom for testing gene-gene interactions. Statistics in Medicine. 2014; 33 (28): 4934-4948. doi:10.1002/sim.6264  
898.   Nakaya N., Kogure M., Saito-Nakaya K., et al. The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study. The European Journal of Public Health. 2014; 24 (1): 45-49. doi:10.1093/eurpub/ckt017  
899.   Nakanaga Keita, Hama Kotaro, Kano Kuniyuki, et al. Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. The Journal of Biochemistry. 2014; 155 (4): 235-241. doi:10.1093/jb/mvt114  
900.   Yoshizawa Junko, Abe Yuko, Oiso Naoki, et al. Variants in melanogenesis-related genes associate with skin cancer risk among Japanese populations. The Journal of Dermatology. 2014; 41 (4): 296-302. doi:10.1111/1346-8138.12432  
901.   Li Na, Yamasaki Kenshi, Saito Rumiko, et al. Alarmin Function of Cathelicidin Antimicrobial Peptide LL37 through IL-36γ Induction in Human Epidermal Keratinocytes. The Journal of Immunology. 2014; 193 (10): 5140-5148. doi:10.4049/jimmunol.1302574  
902.   Iwano Megumi, Igarashi Motoko, Tarutani Yoshiaki, et al. A Pollen Coat–Inducible Autoinhibited Ca 2+ -ATPase Expressed in Stigmatic Papilla Cells Is Required for Compatible Pollination in the Brassicaceae. The Plant Cell. 2014; 26 (2): 636-649. doi:10.1105/tpc.113.121350  
903.   Tsubota-Utsugi Megumi, Satoh Michihiro, Hosaka Miki, et al. Personality Traits as Predictors of Decline in Higher-Level Functional Capacity over a 7-Year Follow-Up in Older Adults: The Ohasama Study. The Tohoku Journal of Experimental Medicine. 2014; 234 (3): 197-207. doi:10.1620/tjem.234.197  
904.   Miyashita A, Hatsuta H, Kikuchi M, et al. Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease. Translational Psychiatry. 2014; 4 (6): e396-e396. doi:10.1038/tp.2014.35  
905.   Nakaya J., Kimura M., Ogishima S., et al. Future Direction of IMIA Standardization. Yearbook of Medical Informatics. 2014; 23 (01): 105-109. doi:10.15265/IY-2014-0010  
906.   鈴木 洋一, 山本 雅之. 【遺伝子医療の現状とゲノム医療の近未来】ゲノムコホート研究とバイオバンク ― 個別化予防と個別化医療の基盤づくりのために. 医学のあゆみ. 2014; 250 ((5)): 321-325. http://www.ishiyaku.co.jp/magazines/ayumi/AyumiArticleDetail.aspx?BC=925005&AC=14110  
907.   関口 敦. 震災直後に認められた脳形態変化の追跡調査-健常大学生における検討. 心身医学. 2014; 54(6) : 563 -563. https://www.jstage.jst.go.jp/article/jjpm/55/8/55_KJ00010004608/_pdf  
908.   富田 博秋. 東日本大震災から4年目を控えて感じること. 精神医学. 2014; 56 (12): pp. 994----995. http://medicalfinder.jp/doi/abs/10.11477/mf.1405204062  
909.   富田 博秋. 災害精神医学に関する研究の課題. 精神神経学雑誌. 2014; : 116: 231--237, 2014. https://journal.jspn.or.jp/Disp?style=abst&vol=116&year=2014&mag=0&number=3&start=231  
910.   小林 朋子, 川目 裕. Roberts症候群 / SCアザラシ肢症候群. 別冊 新領域別症候群シリーズ 神経症候群(第2版)IV. 2014; 29 : 658-660. http://www.nippon-rinsho.co.jp/backnum/s_mokuji/7209sinkei4.html  
911.   小林 朋子, 川目 裕. Robinow症候群. 別冊 新領域別症候群シリーズ 神経症候群(第2版)IV. 2014; 29 : 661-662. http://www.nippon-rinsho.co.jp/backnum/s_mokuji/7209sinkei4.html  
912.   黒澤 靖大, 濱田 裕貴, 菅原 準一. 【異常の早期発見 胎児心拍数モニタリングの読み方 医師との共通認識、冷静な判断につながる最新知識】 飛び込み分娩で救急搬送され、胎児心拍数異常から緊急帝王切開となった事例. 臨床助産ケア:スキルの強化. 2014; 6 (5): 31-38.  
913.   Hoshi Rena, Tomata Yasutake, Kakizaki Masako, et al. [Serum total cholesterol levels and eligibility for long-term care insurance: a prospective cohort study of the Tsurugaya project]. [Nihon kōshū eisei zasshi] Japanese journal of public health. 2013; 60 (8): 435-43. http://www.ncbi.nlm.nih.gov/pubmed/24125765  
914.   Konno Satoshi, Hozawa Atsushi, Munakata Masanori. Blood Pressure Among Public Employees After the Great East Japan Earthquake: The Watari Study. American Journal of Hypertension. 2013; 26 (9): 1059-1063. doi:10.1093/ajh/hpt065  
915.   Hachiya Atsuko, Reeve Aaron B, Marchand Bruno, et al. Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs. Antimicrobial Agents and Chemotherapy. 2013; 57 (9): 4554-4558. doi:10.1128/AAC.00283-13  
916.   Shimane Kazuki, Kawaji Kumi, Miyamoto Fusako, et al. HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains. Antimicrobial Agents and Chemotherapy. 2013; 57 (8): 4035-4038. doi:10.1128/AAC.00237-13  
917.   Maeda Kenji, Desai Darshan V, Aoki Manabu, et al. Delayed emergence of HIV-1 variants resistant to 4’-ethynyl-2-fluoro-2’-deoxyadenosine: comparative sequential passage study with lamivudine, tenofovir, emtricitabine and BMS-986001. Antiviral Therapy. 2013; 19 (2): 179-189. doi:10.3851/IMP2697  
918.   Takahashi Mayumi, Kamei Yasutomi, Ehara Tatsuya, et al. Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes. Biochemical and Biophysical Research Communications. 2013; 434 (4): 873-878. doi:10.1016/j.bbrc.2013.04.041  
919.   Shi Dong, Takano Yoshimasa, Nakazawa Toru, et al. Molecular genetic analysis of primary open-angle glaucoma, normal tension glaucoma, and developmental glaucoma for the VAV2 and VAV3 gene variants in Japanese subjects. Biochemical and Biophysical Research Communications. 2013; 432 (3): 509-512. doi:10.1016/j.bbrc.2013.02.003  
920.   Kojima Kaname, Nariai Naoki, Mimori Takahiro, et al. A statistical variant calling approach from pedigree information and local haplotyping with phase informative reads. Bioinformatics. 2013; Nov 15 (29(22)): 2835-43. doi:10.1093/bioinformatics/btt503  
921.   Nariai Naoki, Hirose Osamu, Kojima Kaname, Nagasaki Masao. TIGAR: transcript isoform abundance estimation method with gapped alignment of RNA-Seq data by variational Bayesian inference. Bioinformatics (Oxford, England). 2013; 29 (18): 2292-9. doi:10.1093/bioinformatics/btt381  
922.   Nagasaki Masao, Fujita André, Sekiya Yayoi, et al. XiP: a computational environment to create, extend and share workflows. Bioinformatics (Oxford, England). 2013; 29 (1): 137-9. doi:10.1093/bioinformatics/bts630  
923.   Hosoya T., Clifford M., Losson R., et al. TRIM28 is essential for erythroblast differentiation in the mouse. Blood. 2013; 122 (23): 3798-3807. doi:10.1182/blood-2013-04-496166  
924.   Miura Naoki, Akitsuki Yuko, Sekiguchi Atsushi, Kawashima Ryuta. Activity in the primary somatosensory cortex induced by reflexological stimulation is unaffected by pseudo-information: a functional magnetic resonance imaging study. BMC Complementary and Alternative Medicine. 2013; 13 (1): 114. doi:10.1186/1472-6882-13-114  
925.   Sekiguchi Atsushi, Sugiura Motoaki, Yokoyama Satoru, et al. Neural correlates of adaptive social responses to real-life frustrating situations: a functional MRI study. BMC Neuroscience. 2013; 14 (1): 29. doi:10.1186/1471-2202-14-29  
926.   Tamai Hiroshi, Ishida Kazuyuki, Murakami Kensuke, et al. Compression neuropathy caused by cancer metastasis to the optic nerve canal. BMC Research Notes. 2013; 6 (1): 546. doi:10.1186/1756-0500-6-546  
927.   Nishio Yousuke, Ogishima Soichi, Ichikawa Masao, et al. Analysis of l-glutamic acid fermentation by using a dynamic metabolic simulation model of Escherichia coli. BMC Systems Biology. 2013; 7 (1): 92. doi:10.1186/1752-0509-7-92  
928.   Mimori Takahiro, Nariai Naoki, Kojima Kaname, et al. iSVP: an integrated structural variant calling pipeline from high-throughput sequencing data. BMC Systems Biology. 2013; 7 (Suppl 6): S8. doi:10.1186/1752-0509-7-S6-S8  
929.   Miyamatsu Naomi, Okamura Tomonori, Nakayama Hirofumi, et al. Public Awareness of Early Symptoms of Stroke and Information Sources about Stroke among the General Japanese Population: The Acquisition of Stroke Knowledge Study. Cerebrovascular Diseases. 2013; 35 (3): 241-249. doi:10.1159/000347066  
930.   Obara Taku, Kikuya Masahiro, Kobayashi Yuka, et al. Associations Between Visit-to-visit Variability in Blood Pressure Measured in the Office and Antihypertensive Drugs: The J-HOME-Morning Study. Clinical and Experimental Hypertension. 2013; 35 (4): 285-290. doi:10.3109/10641963.2013.780070  
931.   Ogishima S, Mizuno S, Kikuchi M, et al. A Map of Alzheimer’s Disease–Signaling Pathways: A Hope for Drug Target Discovery. Clinical Pharmacology & Therapeutics. 2013; 93 (5): 399-401. doi:10.1038/clpt.2013.37  
932.   Wu Kai, Taki Yasuyuki, Sato Kazunori, et al. A longitudinal study of structural brain network changes with normal aging. Frontiers in Human Neuroscience. 2013; 7 : . doi:10.3389/fnhum.2013.00113  
933.   Takeuchi Hikaru, Taki Yasuyuki, Sekiguchi Atsushi, et al. Association of hair iron levels with creativity and psychological variables related to creativity. Frontiers in Human Neuroscience. 2013; 7 : 875. doi:10.3389/fnhum.2013.00875  
934.   Mukai Harumi Y., Suzuki Mikiko, Nagano Masumi, et al. Establishment of erythroleukemic GAK14 cells and characterization of GATA1 N-terminal domain. Genes to Cells. 2013; 18 (10): 886-898. doi:10.1111/gtc.12084  
935.   Suzuki Mikiko, Kobayashi-Osaki Maki, Tsutsumi Shuichi, et al. GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation. Genes to Cells. 2013; 18 (11): 921-933. doi:10.1111/gtc.12086  
936.   Shimizu Ritsuko, Hasegawa Atsushi, Ottolenghi Sergio, et al. Verification of the in vivo activity of three distinct cis -acting elements within the Gata1 gene promoter-proximal enhancer in mice. Genes to Cells. 2013; 18 (11): 1032-1041. doi:10.1111/gtc.12096  
937.   Niu Kaijun, Guo Hui, Kakizaki Masako, et al. A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: A population-based, cross-sectional analysis. Journal of Affective Disorders. 2013; 144 (1-2): 165-170. doi:10.1016/j.jad.2012.04.040  
938.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Comprehensive Classification and Diversity Assessment of Atomic Contacts in Protein–Small Ligand Interactions. Journal of Chemical Information and Modeling. 2013; 53 (1): 241-248. doi:10.1021/ci300377f  
939.   Kon Shunsuke, Minegishi Naoko, Tanabe Kenji, et al. Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia. Journal of Clinical Investigation. 2013; 123 (3): 1123-1137. doi:10.1172/JCI63711  
940.   Kondo Imako, Ojima Toshiyuki, Nakamura Mieko, et al. Consumption of dairy products and death from cardiovascular disease in the Japanese general population: the NIPPON DATA80. Journal of epidemiology / Japan Epidemiological Association. 2013; 23 (1): 47-54. http://www.ncbi.nlm.nih.gov/pubmed/23208514  
941.   Konno Satoshi, Hozawa Atsushi, Miura Yukio, et al. High-normal diastolic blood pressure is a risk for development of microalbuminuria in the general population. Journal of Hypertension. 2013; 31 (4): 798-804. doi:10.1097/HJH.0b013e32835e2146  
942.   Kanno Atsuhiro, Kikuya Masahiro, Asayama Kei, et al. Night-time blood pressure is associated with the development of chronic kidney disease in a general population. Journal of Hypertension. 2013; 31 (12): 2410-2417. doi:10.1097/HJH.0b013e328364dd0f  
943.   Kakizaki Masako, Kuriyama Shinichi, Nakaya Naoki, et al. Long sleep duration and cause-specific mortality according to physical function and self-rated health: the Ohsaki Cohort Study. Journal of Sleep Research. 2013; 22 (2): 209-216. doi:10.1111/j.1365-2869.2012.01053.x  
944.   Souma T., Yamazaki S., Moriguchi T., et al. Plasticity of Renal Erythropoietin-Producing Cells Governs Fibrosis. Journal of the American Society of Nephrology. 2013; 24 (10): 1599-1616. doi:10.1681/ASN.2013010030  
945.   Mutoh Tatsushi, Taki Yasuyuki, Tsubone Hirokazu. Desflurane but not sevoflurane augments laryngeal C-fiber inputs to nucleus tractus solitarii neurons by activating transient receptor potential-A1. Life Sciences. 2013; 92 (14-16): 821-828. doi:10.1016/j.lfs.2013.02.015  
946.   Suzuki Mikiko, Yamazaki Hiromi, Mukai Harumi Y., et al. Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model. Molecular and Cellular Biology. 2013; 33 (8): 1687-1695. doi:10.1128/MCB.01617-12  
947.   Suzuki Takafumi, Shibata Tatsuhiro, Takaya Kai, et al. Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels. Molecular and Cellular Biology. 2013; 33 (12): 2402-2412. doi:10.1128/MCB.00065-13  
948.   Shibata Kyoko, Hozawa Atsushi, Tamiya Gen, et al. The confounding effect of cryptic relatedness for environmental risks of systolic blood pressure on cohort studies. Molecular Genetics & Genomic Medicine. 2013; 1 (1): 45-53. doi:10.1002/mgg3.4  
949.   Yamazaki Shun, Souma Tomokazu, Hirano Ikuo, et al. A mouse model of adult-onset anaemia due to erythropoietin deficiency. Nature Communications. 2013; 4 (1): 1950. doi:10.1038/ncomms2950  
950.   Suzuki Norio, Hirano Ikuo, Pan Xiaoqing, et al. Erythropoietin production in neuroepithelial and neural crest cells during primitive erythropoiesis. Nature Communications. 2013; 4 (1): 2902. doi:10.1038/ncomms3902  
951.   Kon Ayana, Shih Lee-Yung, Minamino Masashi, et al. Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nature Genetics. 2013; 45 (10): 1232-1237. doi:10.1038/ng.2731  
952.   Shi Lihong, Cui Shuaiying, Engel James D, Tanabe Osamu. Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction. Nature Medicine. 2013; 19 (3): 291-294. doi:10.1038/nm.3101  
953.   Suzuki Hideaki, Sumiyoshi Akira, Taki Yasuyuki, et al. Voxel-based morphometry and histological analysis for evaluating hippocampal damage in a rat model of cardiopulmonary resuscitation. NeuroImage. 2013; 77 : 215-221. doi:10.1016/j.neuroimage.2013.03.042  
954.   Taki Yasuyuki, Kinomura Shigeo, Ebihara Satoru, et al. Correlation between pulmonary function and brain volume in healthy elderly subjects. Neuroradiology. 2013; 55 (6): 689-695. doi:10.1007/s00234-013-1157-6  
955.   Shi Dong, Funayama Tomoyo, Mashima Yukihiko, et al. Association of HK2 and NCK2 with Normal Tension Glaucoma in the Japanese Population. PLoS ONE. 2013; 8 (1): e54115. doi:10.1371/journal.pone.0054115  
956.   Miya Masaki, Friedman Matt, Satoh Takashi P., et al. Evolutionary Origin of the Scombridae (Tunas and Mackerels): Members of a Paleogene Adaptive Radiation with 14 Other Pelagic Fish Families. PLoS ONE. 2013; 8 (9): e73535. doi:10.1371/journal.pone.0073535  
957.   Kikuchi Masataka, Ogishima Soichi, Miyamoto Tadashi, et al. Identification of Unstable Network Modules Reveals Disease Modules Associated with the Progression of Alzheimer’s Disease. PLoS ONE. 2013; 8 (11): e76162. doi:10.1371/journal.pone.0076162  
958.   Kasahara Kota, Shirota Matsuyuki, Kinoshita Kengo. Ion Concentration-Dependent Ion Conduction Mechanism of a Voltage-Sensitive Potassium Channel. PLoS ONE. 2013; 8 (2): e56342. doi:10.1371/journal.pone.0056342  
959.   Inohara Taku, Kohsaka Shun, Okamura Tomonori, et al. Long-Term Outcome of Healthy Participants with Atrial Premature Complex: A 15-Year Follow-Up of the NIPPON DATA 90 Cohort. PLoS ONE. 2013; 8 (11): e80853. doi:10.1371/journal.pone.0080853  
960.   Razak Siti Razila Abdul, Ueno Kazuko, Takayama Naoya, et al. Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns. PLoS ONE. 2013; 8 (9): e73532. doi:10.1371/journal.pone.0073532  
961.   Okuyama K., Ikawa T., Gentner B., et al. MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors. Proceedings of the National Academy of Sciences. 2013; 110 (33): 13410-13415. doi:10.1073/pnas.1220710110  
962.   Hiramoto Takafumi, Ebihara Yasuhiro, Mizoguchi Yoko, et al. Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110 (8): 3023-8. doi:10.1073/pnas.1217039110  
963.   Shirota Matsuyuki, Kinoshita Kengo. Analyses of the general rule on residue pair frequencies in local amino acid sequences of soluble, ordered proteins. Protein Science. 2013; 22 (6): 725-733. doi:10.1002/pro.2255  
964.   Nakamura Atsushi, Ebina-Shibuya Risa, Itoh-Nakadai Ari, et al. Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function. The Journal of Experimental Medicine. 2013; 210 (11): 2191-2204. doi:10.1084/jem.20130028  
965.   Hozawa Atsushi, Sugawara Yumi, Tomata Yasutake, et al. Relationship Between Serum Isoflavone Levels and Disability-Free Survival Among Community-Dwelling Elderly Individuals: Nested Case-Control Study of the Tsurugaya Project. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 2013; 68 (4): 465-472. doi:10.1093/gerona/gls198  
966.   菅原 準一. 東北メディカル・メガバンク事業―次世代の医療モデルを実現するために―. 宮城県産婦人科医会誌. 2013; 120 : 6-9.  
967.   事崎 由佳, 竹内 光, 関口 敦, et al. デイリー・ハッスルズに対するバイオフィードバック介入の効果. 人工知能学会論文誌. 2013; 571 : 1-4. https://kaigi.org/jsai/webprogram/2013/pdf/571.pdf  
968.   菅原 準一. 3.11 周産期医療に何が起こったか. 石川産科婦人科学会雑誌. 2013; 3 : 18-19.  
969.   菅原 準一. プライマリケアがお産を守る!大震災後の周産期医療と東北メディカル・メガバンク事業 災害時に母児を守る!その医療活動から見えてきたもの. 日本医事新報. 2013; 4637 : 25-29. http://www.jmedj.co.jp/article/detail.php?article_id=16019  
970.   布施 昇男、清水 愛、木村 雅恵、高野 良真、石 棟、宮澤 晃子、国松 志保、劉 孟林、渡邊 亮、安田 正幸、横山 悠、檜森 紀子、津田 聡、山本 耕太郎、中澤 徹、安田 純、勝岡 史城、小島 要、成相 直樹、松本 光代、元池 育子、長崎 正朗、木下 賢吾、五十嵐 和彦、山本 雅之、新堀 哲也、青木 洋子、松原 洋一、舟山 亮、長嶋 剛史、中山 啓子、眞島 行彦、舟山 智代、田中 光一、原田 高幸、阿部 春樹、福地 健郎、安田 典子、出田 秀尚、鄭 暁東、白石 敦、大橋 祐一、石田 誠夫、原 岳、金森 章. 緑内障のゲノム解析―次世代医療•個別化医療に向けて. 日本眼科学会雑誌. 2013; 118 ((3)): 216-240.  
971.   清元 秀泰. 遺伝子・組織バンクと医療情報の電子化 被災地から最先端創薬を目指して~東北メディカル・メガバンク機構の挑戦~. 臨床薬理. 2013; 44 : 175-176.  
972.   Takano Yoshimasa, Shi Dong, Shimizu Ai, et al. Association of Toll-like Receptor 4 Gene Polymorphisms in Japanese Subjects With Primary Open-Angle, Normal-Tension, and Exfoliation Glaucoma. American Journal of Ophthalmology. 2012; 154 (5): 825-832.e1. doi:10.1016/j.ajo.2012.03.050  
973.   Yasuda Tomohiro, Suzuki Shin, Nagasaki Masao, Miyano Satoru. ChopSticks: High-resolution analysis of homozygous deletions by exploiting concordant read pairs. BMC Bioinformatics. 2012; 13 (1): 279. doi:10.1186/1471-2105-13-279  
974.   Ozawa Manabu, Sakatani Miki, Yao JiQiang, et al. Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst. BMC Developmental Biology. 2012; 12 (1): 33. doi:10.1186/1471-213X-12-33  
975.   Suzuki Satoru, Takai-Igarashi Takako, Fukuoka Yutaka, et al. Systems analysis of inflammatory bowel disease based on comprehensive gene information. BMC Medical Genetics. 2012; 13 (1): 25. doi:10.1186/1471-2350-13-25  
976.   Sekiguchi A, Sugiura M, Taki Y, et al. Causal Relationship Between Psychological Distress After a Severe Earthquake and Brain Structural Changes. Human Science & Technology. 2012; Vol. 10 : 31-37.  
977.   Kotozaki Y, Takeuchi H, Sekiguchi A, et al. Psychological Effects of the Great East Japan Earthquake: Posttraumatic Stress, Psychological Effects and the Cortisol Levels in Women Who Live in the Coastal Disaster Areas. Human Science & Technology. 2012; Vol. 10 : 38-45.  
978.   Ohkura Naganari, Hamaguchi Masahide, Morikawa Hiromasa, et al. T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development. Immunity. 2012; 37 (5): 785-799. doi:10.1016/j.immuni.2012.09.010  
979.   Morita Sumiyo, Takahashi Ryou-u, Yamashita Riu, et al. Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells. International Journal of Molecular Sciences. 2012; 13 (12): 8259-8272. doi:10.3390/ijms13078259  
980.   Obayashi Takeshi, Okamura Yasunobu, Ito Satoshi, et al. COXPRESdb: a database of comparative gene coexpression networks of eleven species for mammals. Nucleic Acids Research. 2012; 41 (D1): D1014-D1020. doi:10.1093/nar/gks1014  
981.   Hirotsu Yosuke, Katsuoka Fumiki, Funayama Ryo, et al. Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks. Nucleic Acids Research. 2012; 40 (20): 10228-10239. doi:10.1093/nar/gks827  
982.   Böck Matthias, Ogishima Soichi, Tanaka Hiroshi, et al. Hub-Centered Gene Network Reconstruction Using Automatic Relevance Determination. PLoS ONE. 2012; 7 (5): e35077. doi:10.1371/journal.pone.0035077  
983.   Koso Hideto, Takeda Haruna, Yew Christopher Chin Kuan, et al. Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109 (44): E2998-3007. doi:10.1073/pnas.1215899109  
984.   Taki Yasuyuki, Kawashima Ryuta. Brain Development in Childhood. The Open Neuroimaging Journal. 2012; 6 : 103-110. doi:10.2174/1874440001206010103  
985.   Akiyama Yasutoshi, Takeuchi Yoichi, Kikuchi Koichi, et al. A metabolomic approach to clarifying the effect of AST-120 on 5/6 nephrectomized rats by capillary electrophoresis with mass spectrometry (CE-MS). Toxins. 2012; 4 (11): 1309-22. doi:10.3390/toxins4111309  
986.   Nouchi Rui, Taki Yasuyuki, Takeuchi Hikaru, et al. Beneficial effects of short-term combination exercise training on diverse cognitive functions in healthy older people: study protocol for a randomized controlled trial. Trials. 2012; 13 (1): 200. doi:10.1186/1745-6215-13-200  
987.   橋爪 寛, 瀧 靖之, 佐々 祐子, et al. 小児における外国語発音能力と外国語音産出に関わる脳活動の発達的変化の関係. 電子情報通信学会技術研究報告. 2012; 112 (145): 19-23. http://www.ieice.org/ken/paper/20120721m0sT/