Tohoku University Tohoku Medical Megabank Organization
2025.06.30

1.   Shimoda Yoshiteru, Kanamori Masayuki, Osawa Shinichiro, et al. Tumor resection in paramedian structures of the frontal lobe poses a risk for corpus callosum infarction. Acta Neurochirurgica. 2025; 167 (1): 137. doi:10.1007/s00701-025-06555-y  
2.   Ishikuro Mami, Fuse Nobuo, Obara Taku, et al. Parental axial lengths and prenatal conditions related to child axial length: The TMM BirThree Cohort Study. AJO International. 2025; 2 (1): 100088. doi:10.1016/j.ajoint.2024.100088  
3.   Kawaguchi Chikana, Ozawa Maki, Hidaka Takanori, et al. Skin health survey on atopic dermatitis among Japanese children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Allergology International. 2025; 74 (2): 246-253. doi:10.1016/j.alit.2024.09.008  
4.   Yoshinaga Kenji, Matsushima Toma, Abe Mitsunari, et al. Age‐disproportionate atrophy in Alzheimer's disease and Parkinson's disease spectra. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 2025; 17 (1): . doi:10.1002/dad2.70048  
5.   Saijo Naoya, Yaoita Hisao, Takayama Jun, et al. A Prevalent TMEM260 Deletion Causes Conotruncal Heart Defects, Including Truncus Arteriosus. American Journal of Medical Genetics Part A. 2025; 197 (3): . doi:10.1002/ajmg.a.63906  
6.   Sudo Koichiro, Uno Kaname, Tamahara Toru, et al. Costimulation with high-fat diet and acidic bile salts may promote Warburg effect in gastric carcinogenesis around the squamocolumnar junction in Gan mice. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2025; 328 (6): G645-G662. doi:10.1152/ajpgi.00305.2024  
7.   Ogino Mako, Takachi Ribeka, Ishihara Junko, et al. Validity of single vs. multiple FFQs in ranking nutrient intake among Japanese adults: the Tohoku Medical Megabank Project. Asia Pacific journal of clinical nutrition. 2025; 34 (3): 451-468. doi:10.6133/apjcn.202506_34(3).0019  
8.   Hayashi Hironori, Hasegawa Kazuya, Saijo Erika, et al. Binding of a potential antibacterial drug, mangiferin, to serine hydroxymethyltransferase from Enterococcus faecium. Biochemical and Biophysical Research Communications. 2025; 743 : 151177. doi:10.1016/j.bbrc.2024.151177  
9.   Abdelhafiz Ahmed Samir, Henderson Marianne K., Kozlakidis Zisis, et al. Transforming Biobanking with AI: Perspectives from Leading Experts. Biopreservation and Biobanking. 2025; : . doi:10.1089/bio.2025.0101  
10.   Hasegawa Ryoko, Nakaya Kumi, Kanazawa Motoyori, Fukudo Shin. Corticotropin-releasing hormone receptor-1 antagonist attenuates visceral hypersensitivity induced by trinitrobenzene sulfonic acid colitis and maternal separation in rats. BioPsychoSocial Medicine. 2025; 19 (1): 5. doi:10.1186/s13030-025-00324-0  
11.   Aoyama Yumi, Yamazaki Hiromi, Nishimura Koutarou, et al. Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages. Blood. 2025; 145 (11): 1149-1163. doi:10.1182/blood.2024025402  
12.   Akimoto Takafumi, Inaba Hiroshi, Ogishima Soichi, et al. Comparison of genotypes and phenotypes for von Willebrand factor gene variants using Japanese genome database. Blood Vessels, Thrombosis & Hemostasis. 2025; : 100070. doi:10.1016/j.bvth.2025.100070  
13.   Karumai-Mori Hikaru, Hamada Hirotaka, Iwama Noriyuki, et al. Impact of maternal smoking and secondhand smoke exposure during singleton pregnancy on placental abruption: analysis of a prospective cohort study (the Japan Environment and Children’s Study). BMJ Open. 2025; 15 (3): e089499. doi:10.1136/bmjopen-2024-089499  
14.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Has the impact of cigarette smoking on mortality been underestimated by overlooking second-hand smoke? Tohoku medical megabank community-based cohort study. BMJ Public Health. 2025; 3 (1): e001746. doi:10.1136/bmjph-2024-001746  
15.   Nakagawa Seishu, Takeuchi Hikaru, Taki Yasuyuki, et al. Suppression of Deactivation of Working Memory and Promotion of Activation of Sustained Attention in the Default Mode Network Are Affected by Schizotypy in a Large Sample of Nonclinical Subjects. Brain and Behavior. 2025; 15 (5): . doi:10.1002/brb3.70449  
16.   Tojo Maki, Iwata Hiroyoshi, Tamura Naomi, et al. Association between small for gestational age and motor coordination difficulties in children aged 5–6 years: Insights from the Hokkaido Study on Environment and Children's Health. Brain and Development. 2025; 47 (1): 104296. doi:10.1016/j.braindev.2024.10.004  
17.   Shirota Hidekazu, Miyake Akimitsu, Kawamura Maako, et al. Regional Differences in the Frequency of BRCA1 and BRCA2 Variants in Northeastern Japan: A Cohort Study. Cancer Medicine. 2025; 14 (8): . doi:10.1002/cam4.70443  
18.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Association Between Sodium- and Potassium-Related Urinary Markers and the Prevalence of Atrial Fibrillation. Circulation Journal. 2025; 89 (6): CJ-24-0780. doi:10.1253/circj.CJ-24-0780  
19.   Nakayama Shingo, Satoh Michihiro, Toyama Maya, et al. Comparison of the incidence of proteinuria and changes in eGFR among febuxostat and topiroxostat users. Clinical and Experimental Nephrology. 2025; 29 (6): 797-806. doi:10.1007/s10157-025-02630-x  
20.   Iwafuchi Sota, Uchida Nao, Saijo Naoya, et al. Idiopathic infantile hypercalcemia with a CYP24A1 variant triggered by vitamin D supplementation in fortified milk: A case report. Clinical Pediatric Endocrinology. 2025; 34 (1): 2024-0049. doi:10.1297/cpe.2024-0049  
21.   Shima Hirohito, Miura Akinobu, Kawashima Sayaka, et al. Solitary median maxillary central incisor syndrome caused by 22q11.2 microdeletion. Clinical Pediatric Endocrinology. 2025; 34 (1): 2024-0024. doi:10.1297/cpe.2024-0024  
22.   Suzuki Nonoka, Kojima Kaname, Malvica Silvia, et al. Deep learning-based histopathological assessment of tubulo-interstitial injury in chronic kidney diseases. Communications Medicine. 2025; 5 (1): 3. doi:10.1038/s43856-024-00708-3  
23.   Honma Mariko, Suzuki Naoto, Goto Mikako, et al. A case series study on the safety of cefditoren pivoxil use during the first trimester of pregnancy in Japan. Congenital Anomalies. 2025; 65 (1): . doi:10.1111/cga.12588  
24.   Kubota Takafumi, Ngadimon Irma Wati, Ohseto Hisashi, et al. Predictive value of the polygenic risk score for developing epilepsy: a systematic review and meta-analysis. Epilepsy & Behavior. 2025; 169 : 110438. doi:10.1016/j.yebeh.2025.110438  
25.   ISHIDA Saeko, TAGUCHI Keiko, IIDA Ryuya, et al. Diverse Cre recombinase expression pattern in Albumin-Cre driver rats. Experimental Animals. 2025; : 24-0174. doi:10.1538/expanim.24-0174  
26.   Wang Ke, Baird Liam, Yamamoto Masayuki. The clinical-grade CBP/ p300 inhibitor CCS1477 represses the global NRF2-dependent cytoprotective transcription program and re-sensitizes cancer cells to chemotherapeutic drugs. Free Radical Biology and Medicine. 2025; 233 : 102-117. doi:10.1016/j.freeradbiomed.2025.03.034  
27.   Komiyama Takamasa, Ohi Takashi, Miyoshi Yoshitada, et al. Number of teeth and functional disability in community‐dwelling older adults. Gerodontology. 2025; 42 (1): 86-92. doi:10.1111/ger.12775  
28.   Tokioka Sayuri, Takase Masato, Nakaya Naoki, et al. Sex difference in genetic risk in the prevalence of atrial fibrillation. Heart Rhythm. 2025; : . doi:10.1016/j.hrthm.2025.03.1974  
29.   Toyama Maya, Satoh Michihiro, Hashimoto Hideaki, et al. Association between equivalized annual household income and regular medical visits for hypertensive patients since the COVID-19 outbreak. Hypertension Research. 2025; 48 (2): 786-795. doi:10.1038/s41440-024-02067-x  
30.   Satoh Michihiro, Metoki Hirohito, Murakami Takahisa, et al. Home blood pressure control and prescribing patterns of anti-hypertensive medications in a home blood pressure-based hypertension-specialized clinic in Japan: a sub-analysis of the Ohasama study. Hypertension Research. 2025; 48 (1): 26-36. doi:10.1038/s41440-024-01954-7  
31.   Satoh Michihiro, Ohkubo Takayoshi, Miura Katsuyuki, et al. Long-term risk of cardiovascular mortality according to age group and blood pressure categories of the latest guideline. Hypertension Research. 2025; 48 (4): 1428-1433. doi:10.1038/s41440-025-02151-w  
32.   Satoh Michihiro, Nobayashi Hiroki, Nakayama Shingo, Hirohito Metoki. Nighttime blood pressure in patients with chronic kidney disease: ambulatory blood pressure monitoring status in Japan and future implementation. Hypertension Research. 2025; 48 (4): 1437-1439. doi:10.1038/s41440-025-02159-2  
33.   Satoh Michihiro, Tatsumi Yukako, Nakayama Shingo, et al. Self-measurement of blood pressure at home using a cuff device for change in blood pressure levels: systematic review and meta-analysis. Hypertension Research. 2025; 48 (2): 574-591. doi:10.1038/s41440-024-01981-4  
34.   Ishikuro Mami, Obara Taku, Hasegawa Mayu, et al. Subsequent high blood pressure and hypertension by hypertensive disorders of pregnancy: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Hypertension Research. 2025; 48 (1): 68-76. doi:10.1038/s41440-024-01936-9  
35.   Metoki Hirohito, Nobayashi Hiroki, Satoh Michihiro. The significance of ambulatory blood pressure monitoring for evaluating circadian blood pressure variations affected by alcohol consumption. Hypertension Research. 2025; 48 (5): 1807-1810. doi:10.1038/s41440-025-02167-2  
36.   Hishinuma Eiji, Shigeta Shogo, Matsukawa Naomi, et al. Sequential Plasma Metabolome and Proteome Analyses to Develop a Novel Monitoring Strategy for Patients with Epithelial Ovarian Cancer: A Pilot Study. International Journal of Molecular Sciences. 2025; 26 (12): 5435. doi:10.3390/ijms26125435  
37.   Mori Naoko, Mugikura Shunji, Abe Yuto, et al. STAT image reporting in a large-scale cohort: types, frequency, and insights from the Tohoku Medical Megabank Brain MRI Study. Japanese Journal of Radiology. 2025; : . doi:10.1007/s11604-025-01800-x  
38.   Nagino Ken, Akasaki Yasutsugu, Fuse Nobuo, et al. Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study. JMIR Research Protocols. 2025; 14 : e67862. doi:10.2196/67862  
39.   Ishikawa Tomofumi, Sakai Takamasa, Noda Aoi, et al. Inclination of antidepressant medication continuation during pregnancy between 2012 and 2023 in Japan: A cohort study. Journal of Affective Disorders. 2025; 374 : 640-645. doi:10.1016/j.jad.2025.01.044  
40.   Tateishi Masaki, Goto Kota, Hishinuma Eiji, et al. Double prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy. Journal of Biological Chemistry. 2025; 301 (4): 108384. doi:10.1016/j.jbc.2025.108384  
41.   Satoh Michihiro, Nakayama Shingo, Hashimoto Hideaki, et al. Differential coronary heart disease risk among antihypertensive and lipid-lowering medication users versus non-users: A real-world data analysis. Journal of Clinical Lipidology. 2025; 19 (2): 294-302. doi:10.1016/j.jacl.2024.12.006  
42.   Inoue Yui, Yokoyama Maki, Inoue Shota, et al. Association between paternal physique and obesity in children at the age of 3 years: the Japan Environment and Children’s Study. Journal of Developmental Origins of Health and Disease. 2025; 16 : e17. doi:10.1017/S2040174424000473  
43.   Tagami Kazuma, Iwama Noriyuki, Hamada Hirotaka, et al. Advanced maternal age is a risk factor for both early and late gestational diabetes mellitus: The Japan Environment and Children's Study. Journal of Diabetes Investigation. 2025; 16 (4): 735-743. doi:10.1111/jdi.14400  
44.   Ishida Noriyuki, Harada Sei, Toki Ryota, et al. Causal relationship between body mass index and insulin resistance: Linear and nonlinear Mendelian randomization study in a Japanese population. Journal of Diabetes Investigation. 2025; : . doi:10.1111/jdi.14377  
45.   Kiuchi Sakura, Nakaya Kumi, Cooray Upul, et al. A Principal Component Analysis of Metabolome and Cognitive Decline Among Japanese Older Adults: Cross-sectional Analysis Using Tohoku Medical Megabank Cohort Study Data. Journal of Epidemiology. 2025; 35 (1): JE20240099. doi:10.2188/jea.JE20240099  
46.   Murakami Keiko, Ishihara Junko, Takachi Ribeka, et al. Validity and Reproducibility of Food Group Intakes in a Self-administered Food Frequency Questionnaire for Genomic and Omics Research: The Tohoku Medical Megabank Project. Journal of Epidemiology. 2025; 35 (3): JE20240064. doi:10.2188/jea.JE20240064  
47.   Nakaya Naoki, Nakaya Kumi, Kogure Mana, et al. Degree of housing damage caused by the Great East Japan Earthquake and all-cause mortality in the community-based cohort study of the Tohoku Medical Megabank Project. Journal of Epidemiology and Community Health. 2025; 79 (6): 451-458. doi:10.1136/jech-2024-223084  
48.   Sawahashi Motoi, Kakuta Yoichi, Naito Takeo, et al. Autoantibodies against endothelial protein C receptor and integrin αvβ6 predict the development of ulcerative colitis. Journal of Gastroenterology. 2025; : . doi:10.1007/s00535-025-02263-7  
49.   Kawahara Tomoki, Nawa Nobutoshi, Murakami Keiko, et al. Genetic effects on gestational diabetes mellitus and their interactions with environmental factors among Japanese women. Journal of Human Genetics. 2025; 70 (5): 265-273. doi:10.1038/s10038-025-01330-4  
50.   Minn Aye Ko Ko, Matsuzaki Motomichi, Narita Akira, et al. Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank. Journal of Human Genetics. 2025; 70 (6): 287-296. doi:10.1038/s10038-025-01331-3  
51.   Ohneda Kinuko, Suzuki Yoichi, Hamanaka Yohei, et al. Returning genetic risk information for hereditary cancers to participants in a population-based cohort study in Japan. Journal of Human Genetics. 2025; 70 (3): 147-157. doi:10.1038/s10038-024-01314-w  
52.   Takahara Aoi, Nakatsu Toru, Hirata Kazushige, et al. Elucidation of Postfusion Structures of the Measles Virus F Protein for the Structure-Based Design of Fusion Inhibitors. Journal of Medicinal Chemistry. 2025; 68 (3): 3123-3133. doi:10.1021/acs.jmedchem.4c02337  
53.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Effect of Social Support on Caregiver's Functional Disability Due to Spouse's Functional Disability. Journal of the American Medical Directors Association. 2025; 26 (1): 105324. doi:10.1016/j.jamda.2024.105324  
54.   Shi Ge, Sato Kota, Takahashi Nana, et al. AAV2-driven endothelin induces chronic reduced retinal blood flow/retinal ganglion cell loss in rats. Life Science Alliance. 2025; 8 (8): e202403087. doi:10.26508/lsa.202403087  
55.   Narita Daisuke, Hishinuma Eiji, Ebina-Shibuya Risa, et al. Histological and genetic features and therapeutic responses of lung cancers explored via the global analysis of their metabolome profile. Lung Cancer. 2025; 200 : 108082. doi:10.1016/j.lungcan.2025.108082  
56.   Oshikiri Hiroyuki, Taguchi Keiko, Hirose Wataru, et al. Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma. Molecular and Cellular Biology. 2025; 45 (2): 79-97. doi:10.1080/10985549.2024.2438817  
57.   Iwamura Yuma, Nakai Taku, Kato Koichiro, et al. Erythropoietin Production in Embryonic Neural Cells is Controlled by Hypoxia Signaling and Histone Deacetylases with an Undifferentiated Cellular State. Molecular and Cellular Biology. 2025; 45 (1): 32-45. doi:10.1080/10985549.2024.2428717  
58.   Hatzikotoulas Konstantinos, Southam Lorraine, Stefansdottir Lilja, et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature. 2025; 641 (8065): 1217-1224. doi:10.1038/s41586-025-08771-z  
59.   Yamamoto Yuji, Shirai Yuya, Sonehara Kyuto, et al. Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases. Nature Communications. 2025; 16 (1): 3765. doi:10.1038/s41467-025-58149-y  
60.   Sun Zhengkang, Kirikae Hinako, He Xiaofeng, et al. Effects of pharmacological inhibition of FABP4 during gestation and lactation on offspring neurodevelopment and behavior. Neuroscience Letters. 2025; 853 : 138199. doi:10.1016/j.neulet.2025.138199  
61.   Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Exploring the association between human breast milk lipids and early adiposity rebound in children: A case-control study. Nutrition. 2025; 135 : 112739. doi:10.1016/j.nut.2025.112739  
62.   Fuse Nobuo, Anzawa Hayato, Sakurai Miyuki, et al. Genome-Wide Association Study of Intraocular Pressure in Population-Based Cohorts in Japan: The Tohoku Medical Megabank Organization Eye Study. Ophthalmology Science. 2025; 5 (5): 100821. doi:10.1016/j.xops.2025.100821  
63.   Shiraki Akihiko, Hirayama Atsushi, Fuse Nobuo, et al. Prevalence and Associations of Epiretinal Membrane by OCT in a Japanese Population-Based Cohort: Tohoku Medical Megabank Organization Eye Study. Ophthalmology Science. 2025; 5 (4): 100752. doi:10.1016/j.xops.2025.100752  
64.   Takahashi Ippei, Shinoda Genki, Ueno Fumihiko, et al. Respiratory syncytial virus infection, non‐respiratory syncytial virus respiratory infections, and later wheezing. Pediatrics International. 2025; 67 (1): . doi:10.1111/ped.70050  
65.   Imai Haruka, Suzuki Jun, Mizuno Tomoki, et al. The effect of antibiotic prescription in non-critically ill hospitalized patients with COVID-19: A Japanese inpatient database study. PLOS ONE. 2025; 20 (3): e0318803. doi:10.1371/journal.pone.0318803  
66.   Bekker Gert‐Jan, Nagao Chioko, Shirota Matsuyuki, et al. Protein Data Bank Japan: Improved tools for sequence‐oriented analysis of protein structures. Protein Science. 2025; 34 (3): . doi:10.1002/pro.70052  
67.   Bekker Gert‐Jan, Nagao Chioko, Shirota Matsuyuki, et al. Protein Data Bank Japan: Improved tools for sequence‐oriented analysis of protein structures. Protein Science. 2025; 34 (3): . doi:10.1002/pro.70052  
68.   Nakatochi Masahiro, Kushima Itaru, Aleksic Branko, et al. Copy number variations in RNF216 and postsynaptic membrane–associated genes are associated with bipolar disorder: a case‐control study in the Japanese population. Psychiatry and Clinical Neurosciences. 2025; 79 (1): 12-20. doi:10.1111/pcn.13752  
69.   Orui Masatsugu, Ishikuro Mami, Obara Taku, et al. Longitudinal association between the duration of eye gaze fixation on social information and specific symptoms of neurodevelopmental disorders in children: A large‐scale community‐based cohort study. Psychiatry and Clinical Neurosciences Reports. 2025; 4 (2): . doi:10.1002/pcn5.70095  
70.   Yamada Yuto, Fujiwara Masaki, Nakaya Naoki, et al. Trends in uptake of cancer screening among people with severe mental illness before and after the COVID‐19 pandemic in Japan: A repeated cross‐sectional study. Psychiatry and Clinical Neurosciences Reports. 2025; 4 (1): . doi:10.1002/pcn5.70062  
71.   Nakaya Naoki, Nakaya Kumi, Sone Toshimasa, et al. Concordance of Cancer Screening Attendance Among Spouse Couples: A Cross‐Sectional Survey of the Tohoku Medical Megabank Project. Psycho-Oncology. 2025; 34 (5): . doi:10.1002/pon.70158  
72.   Cuadrado Antonio, Cazalla Eduardo, Bach Anders, et al. Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases. Redox Biology. 2025; 81 : 103569. doi:10.1016/j.redox.2025.103569  
73.   Wang Hongxin, Iwama Noriyuki, Yuwaki Keiichi, et al. Association of Parity with Type 2 Diabetes Mellitus in Japan. Reproductive Sciences. 2025; 32 (2): 366-381. doi:10.1007/s43032-024-01752-z  
74.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Genetic risk, lifestyle adherence, and risk of developing hyperuricaemia in a Japanese population. Rheumatology. 2025; 64 (5): 2591-2600. doi:10.1093/rheumatology/keae492  
75.   Gusareva Elena S., Ghosh Amit Gourav, Kharkov Vladimir N., et al. From North Asia to South America: Tracing the longest human migration through genomic sequencing. Science. 2025; 388 (6748): . doi:10.1126/science.adk5081  
76.   Scherer Thomas, Metz Matthäus, Beghini Marianna, et al. A direct effect of the hematocrit on blood glucose: Evidence from hypoxia- and erythropoietin-treated mice. Science Advances. 2025; 11 (16): . doi:10.1126/sciadv.adt7366  
77.   Toki Ryota, Fushiki Sotaro, Kojima Shun, et al. Genome-wide association study of plasma amino acids and Mendelian randomization for cardiometabolic traits. Scientific Reports. 2025; 15 (1): 14569. doi:10.1038/s41598-025-98992-z  
78.   Ohseto Hisashi, Ishikuro Mami, Obara Taku, et al. Preeclampsia prediction with maternal and paternal polygenic risk scores: the TMM BirThree Cohort Study. Scientific Reports. 2025; 15 (1): 13743. doi:10.1038/s41598-025-97291-x  
79.   Kodate Shun, Sato Mitsuharu, Hishinuma Eiji, et al. Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies. Scientific Reports. 2025; 15 (1): 17035. doi:10.1038/s41598-025-01634-7  
80.   Ohseto Hisashi, Ishikuro Mami, Chen Geng, et al. Synergistic effects of cardiovascular health and social isolation on adverse pregnancy outcomes. Scientific Reports. 2025; 15 (1): 18924. doi:10.1038/s41598-025-03652-x  
81.   Kawaguchi Chikana, Ishikuro Mami, Saito Ryota, et al. Maternal Fasting Plasma Glucose Level in Early Gestation and Developmental Delay in 2-year-old Children. The Journal of Clinical Endocrinology & Metabolism. 2025; : . doi:10.1210/clinem/dgae825  
82.   Izumi Seiya, Nishimura Misato, Iwama Noriyuki, et al. Pregnancy and Postpartum Trends in Self‐Measured Blood Pressure and Derived Indices: The BOSHI Study. The Journal of Clinical Hypertension. 2025; 27 (1): . doi:10.1111/jch.14949  
83.   Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Association Between Human Milk Oligosaccharides and Early Adiposity Rebound in Children: A Case–Control Study of the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Journal of Nutrition. 2025; 155 (5): 1498-1507. doi:10.1016/j.tjnut.2025.02.024  
84.   Seki Daizo, Komiyama Takamasa, Ohi Takashi, et al. Effects of dental prostheses and occlusal force on adverse health outcomes in community-dwelling older adults lacking functional dentition: The Longitudinal Study of the Tsurugaya Project. The Journal of nutrition, health and aging. 2025; 29 (6): 100534. doi:10.1016/j.jnha.2025.100534  
85.   Yamazaki Teiichiro, Nomura Kyoko, Satoh Michihiro, et al. Association Between the Number of Deliveries and Cognitive Impairment Considering the Presence of Subclinical Cerebrovascular Diseases: The Ohasama Study. The Tohoku Journal of Experimental Medicine. 2025; 266 (1): 2024.J139. doi:10.1620/tjem.2024.J139  
86.   Kobayashi Mika, Kobayashi Tomoko, Obara Taku, et al. Gaze Patterns of Children with Communication Difficulties Associated with Core Symptoms of Autism Spectrum Disorder. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J074. doi:10.1620/tjem.2025.J074  
87.   Shinoda Genki, Matsuzaki Fumiko, Ueno Fumihiko, et al. Impact of Telework on Health and Lifestyle Changes During the COVID-19 Pandemic in Japan. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J014. doi:10.1620/tjem.2025.J014  
88.   Mori Naoko, Mugikura Shunji, Hozawa Atsushi, et al. Language Registration-Based Scoring System for Handwritten Logical Memory of Wechsler Memory Scale-Revised: Developed and Validated in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J006. doi:10.1620/tjem.2025.J006  
89.   Shimoda Yoshiteru, Shibahara Ichiyo, Kanamori Masayuki, et al. Clinical Effect of Ventricular Entry During Resection of Isocitrate Dehydrogenase-Wildtype Glioblastoma: A Multi-Institutional Analysis. World Neurosurgery. 2025; 195 : 123643. doi:10.1016/j.wneu.2024.123643  
90.   Shimoda Yoshiteru, Kanamori Masayuki, Yamashita Shota, et al. Residual Pattern of the Hyperintense Area on T2-Weighted Magnetic Resonance Imaging After Initial Treatment Predicts the Pattern and Location of Recurrence in Patients with Newly Diagnosed Glioblastoma. World Neurosurgery. 2025; 193 : 517-532. doi:10.1016/j.wneu.2024.10.012  
91.   Chen Geng, Ishikuro Mami, Ohseto Hisashi, et al. Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Acta Obstetricia et Gynecologica Scandinavica. 2024; 103 (6): 1192-1200. doi:10.1111/aogs.14820  
92.   Ishikawa Tomofumi, Sakai Takamasa, Iwama Noriyuki, et al. Association between exposure to atypical antipsychotics during pregnancy and risk of miscarriage. Acta Psychiatrica Scandinavica. 2024; 150 (6): 562-572. doi:10.1111/acps.13755  
93.   Akaishi Tetsuya, Tarasawa Kunio, Fushimi Kiyohide, et al. Demographic profiles and risk factors for mortality in acute meningitis: A nationwide population‐based observational study. Acute Medicine & Surgery. 2024; 11 (1): . doi:10.1002/ams2.920  
94.   Mizuno Satoshi, Nagaie Satoshi, Sugawara Junichi, et al. Early prediction of hypertensive disorders of pregnancy toward preventive early intervention. AJOG Global Reports. 2024; 4 (4): 100383. doi:10.1016/j.xagr.2024.100383  
95.   Kawashima Aritomo, Kodama Kaori, Okubo Yukimune, et al. Long‐term clinical observation of patients with heterozygous KIF1A variants. American Journal of Medical Genetics Part A. 2024; 194 (10): . doi:10.1002/ajmg.a.63656  
96.   Takahashi Tsukasa, Tomita Hasumi, Hamada Hirotaka, et al. Transcatheter arterial embolization outperforms surgery in reducing blood transfusions for postpartum vulvovaginal hematoma. American Journal of Obstetrics and Gynecology. 2024; 231 (6): 653.e1-653.e8. doi:10.1016/j.ajog.2024.03.016  
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