Tohoku University Tohoku Medical Megabank Organization
2025.05.01

1.   Ishikuro Mami, Fuse Nobuo, Obara Taku, et al. Parental axial lengths and prenatal conditions related to child axial length: The TMM BirThree Cohort Study. AJO International. 2025; 2 (1): 100088. doi:10.1016/j.ajoint.2024.100088  
2.   Kawaguchi Chikana, Ozawa Maki, Hidaka Takanori, et al. Skin health survey on atopic dermatitis among Japanese children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Allergology International. 2025; 74 (2): 246-253. doi:10.1016/j.alit.2024.09.008  
3.   Yoshinaga Kenji, Matsushima Toma, Abe Mitsunari, et al. Age‐disproportionate atrophy in Alzheimer's disease and Parkinson's disease spectra. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 2025; 17 (1): . doi:10.1002/dad2.70048  
4.   Saijo Naoya, Yaoita Hisao, Takayama Jun, et al. A Prevalent TMEM260 Deletion Causes Conotruncal Heart Defects, Including Truncus Arteriosus. American Journal of Medical Genetics Part A. 2025; 197 (3): . doi:10.1002/ajmg.a.63906  
5.   Hayashi Hironori, Hasegawa Kazuya, Saijo Erika, et al. Binding of a potential antibacterial drug, mangiferin, to serine hydroxymethyltransferase from Enterococcus faecium. Biochemical and Biophysical Research Communications. 2025; 743 : 151177. doi:10.1016/j.bbrc.2024.151177  
6.   Aoyama Yumi, Yamazaki Hiromi, Nishimura Koutarou, et al. Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages. Blood. 2025; 145 (11): 1149-1163. doi:10.1182/blood.2024025402  
7.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Has the impact of cigarette smoking on mortality been underestimated by overlooking second-hand smoke? Tohoku medical megabank community-based cohort study. BMJ Public Health. 2025; 3 (1): e001746. doi:10.1136/bmjph-2024-001746  
8.   Tojo Maki, Iwata Hiroyoshi, Tamura Naomi, et al. Association between small for gestational age and motor coordination difficulties in children aged 5–6 years: Insights from the Hokkaido Study on Environment and Children's Health. Brain and Development. 2025; 47 (1): 104296. doi:10.1016/j.braindev.2024.10.004  
9.   Tokioka Sayuri, Nakaya Naoki, Hatanaka Rieko, et al. Association Between Sodium- and Potassium-Related Urinary Markers and the Prevalence of Atrial Fibrillation. Circulation Journal. 2025; : CJ-24-0780. doi:10.1253/circj.CJ-24-0780  
10.   Nakayama Shingo, Satoh Michihiro, Toyama Maya, et al. Comparison of the incidence of proteinuria and changes in eGFR among febuxostat and topiroxostat users. Clinical and Experimental Nephrology. 2025; : . doi:10.1007/s10157-025-02630-x  
11.   Iwafuchi Sota, Uchida Nao, Saijo Naoya, et al. Idiopathic infantile hypercalcemia with a CYP24A1 variant triggered by vitamin D supplementation in fortified milk: A case report. Clinical Pediatric Endocrinology. 2025; 34 (1): 2024-0049. doi:10.1297/cpe.2024-0049  
12.   Shima Hirohito, Miura Akinobu, Kawashima Sayaka, et al. Solitary median maxillary central incisor syndrome caused by 22q11.2 microdeletion. Clinical Pediatric Endocrinology. 2025; 34 (1): 2024-0024. doi:10.1297/cpe.2024-0024  
13.   Suzuki Nonoka, Kojima Kaname, Malvica Silvia, et al. Deep learning-based histopathological assessment of tubulo-interstitial injury in chronic kidney diseases. Communications Medicine. 2025; 5 (1): 3. doi:10.1038/s43856-024-00708-3  
14.   Honma Mariko, Suzuki Naoto, Goto Mikako, et al. A case series study on the safety of cefditoren pivoxil use during the first trimester of pregnancy in Japan. Congenital Anomalies. 2025; 65 (1): . doi:10.1111/cga.12588  
15.   ISHIDA Saeko, TAGUCHI Keiko, IIDA Ryuya, et al. Diverse Cre recombinase expression pattern in Albumin-Cre driver rats. Experimental Animals. 2025; : 24-0174. doi:10.1538/expanim.24-0174  
16.   Komiyama Takamasa, Ohi Takashi, Miyoshi Yoshitada, et al. Number of teeth and functional disability in community‐dwelling older adults. Gerodontology. 2025; 42 (1): 86-92. doi:10.1111/ger.12775  
17.   Tokioka Sayuri, Takase Masato, Nakaya Naoki, et al. Sex difference in genetic risk in the prevalence of atrial fibrillation. Heart Rhythm. 2025; : . doi:10.1016/j.hrthm.2025.03.1974  
18.   Toyama Maya, Satoh Michihiro, Hashimoto Hideaki, et al. Association between equivalized annual household income and regular medical visits for hypertensive patients since the COVID-19 outbreak. Hypertension Research. 2025; 48 (2): 786-795. doi:10.1038/s41440-024-02067-x  
19.   Satoh Michihiro, Metoki Hirohito, Murakami Takahisa, et al. Home blood pressure control and prescribing patterns of anti-hypertensive medications in a home blood pressure-based hypertension-specialized clinic in Japan: a sub-analysis of the Ohasama study. Hypertension Research. 2025; 48 (1): 26-36. doi:10.1038/s41440-024-01954-7  
20.   Satoh Michihiro, Tatsumi Yukako, Nakayama Shingo, et al. Self-measurement of blood pressure at home using a cuff device for change in blood pressure levels: systematic review and meta-analysis. Hypertension Research. 2025; 48 (2): 574-591. doi:10.1038/s41440-024-01981-4  
21.   Ishikuro Mami, Obara Taku, Hasegawa Mayu, et al. Subsequent high blood pressure and hypertension by hypertensive disorders of pregnancy: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Hypertension Research. 2025; 48 (1): 68-76. doi:10.1038/s41440-024-01936-9  
22.   Ishikawa Tomofumi, Sakai Takamasa, Noda Aoi, et al. Inclination of antidepressant medication continuation during pregnancy between 2012 and 2023 in Japan: A cohort study. Journal of Affective Disorders. 2025; 374 : 640-645. doi:10.1016/j.jad.2025.01.044  
23.   Satoh Michihiro, Nakayama Shingo, Hashimoto Hideaki, et al. Differential coronary heart disease risk among antihypertensive and lipid-lowering medication users versus non-users: A real-world data analysis. Journal of Clinical Lipidology. 2025; 19 (2): 294-302. doi:10.1016/j.jacl.2024.12.006  
24.   Tagami Kazuma, Iwama Noriyuki, Hamada Hirotaka, et al. Advanced maternal age is a risk factor for both early and late gestational diabetes mellitus: The Japan Environment and Children's Study. Journal of Diabetes Investigation. 2025; 16 (4): 735-743. doi:10.1111/jdi.14400  
25.   Kiuchi Sakura, Nakaya Kumi, Cooray Upul, et al. A Principal Component Analysis of Metabolome and Cognitive Decline Among Japanese Older Adults: Cross-sectional Analysis Using Tohoku Medical Megabank Cohort Study Data. Journal of Epidemiology. 2025; 35 (1): JE20240099. doi:10.2188/jea.JE20240099  
26.   Murakami Keiko, Ishihara Junko, Takachi Ribeka, et al. Validity and Reproducibility of Food Group Intakes in a Self-administered Food Frequency Questionnaire for Genomic and Omics Research: The Tohoku Medical Megabank Project. Journal of Epidemiology. 2025; 35 (3): JE20240064. doi:10.2188/jea.JE20240064  
27.   Nakaya Naoki, Nakaya Kumi, Kogure Mana, et al. Degree of housing damage caused by the Great East Japan Earthquake and all-cause mortality in the community-based cohort study of the Tohoku Medical Megabank Project. Journal of Epidemiology and Community Health. 2025; : jech-2024-223084. doi:10.1136/jech-2024-223084  
28.   Minn Aye Ko Ko, Matsuzaki Motomichi, Narita Akira, et al. Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank. Journal of Human Genetics. 2025; : . doi:10.1038/s10038-025-01331-3  
29.   Ohneda Kinuko, Suzuki Yoichi, Hamanaka Yohei, et al. Returning genetic risk information for hereditary cancers to participants in a population-based cohort study in Japan. Journal of Human Genetics. 2025; 70 (3): 147-157. doi:10.1038/s10038-024-01314-w  
30.   Takahara Aoi, Nakatsu Toru, Hirata Kazushige, et al. Elucidation of Postfusion Structures of the Measles Virus F Protein for the Structure-Based Design of Fusion Inhibitors. Journal of Medicinal Chemistry. 2025; 68 (3): 3123-3133. doi:10.1021/acs.jmedchem.4c02337  
31.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Effect of Social Support on Caregiver's Functional Disability Due to Spouse's Functional Disability. Journal of the American Medical Directors Association. 2025; 26 (1): 105324. doi:10.1016/j.jamda.2024.105324  
32.   Narita Daisuke, Hishinuma Eiji, Ebina-Shibuya Risa, et al. Histological and genetic features and therapeutic responses of lung cancers explored via the global analysis of their metabolome profile. Lung Cancer. 2025; 200 : 108082. doi:10.1016/j.lungcan.2025.108082  
33.   Oshikiri Hiroyuki, Taguchi Keiko, Hirose Wataru, et al. Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma. Molecular and Cellular Biology. 2025; 45 (2): 79-97. doi:10.1080/10985549.2024.2438817  
34.   Iwamura Yuma, Nakai Taku, Kato Koichiro, et al. Erythropoietin Production in Embryonic Neural Cells is Controlled by Hypoxia Signaling and Histone Deacetylases with an Undifferentiated Cellular State. Molecular and Cellular Biology. 2025; 45 (1): 32-45. doi:10.1080/10985549.2024.2428717  
35.   Yamamoto Yuji, Shirai Yuya, Sonehara Kyuto, et al. Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases. Nature Communications. 2025; 16 (1): 3765. doi:10.1038/s41467-025-58149-y  
36.   Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Exploring the association between human breast milk lipids and early adiposity rebound in children: A case-control study. Nutrition. 2025; 135 : 112739. doi:10.1016/j.nut.2025.112739  
37.   Nakatochi Masahiro, Kushima Itaru, Aleksic Branko, et al. Copy number variations in RNF216 and postsynaptic membrane–associated genes are associated with bipolar disorder: a case‐control study in the Japanese population. Psychiatry and Clinical Neurosciences. 2025; 79 (1): 12-20. doi:10.1111/pcn.13752  
38.   Yamada Yuto, Fujiwara Masaki, Nakaya Naoki, et al. Trends in uptake of cancer screening among people with severe mental illness before and after the COVID‐19 pandemic in Japan: A repeated cross‐sectional study. Psychiatry and Clinical Neurosciences Reports. 2025; 4 (1): . doi:10.1002/pcn5.70062  
39.   Nakaya Naoki, Nakaya Kumi, Sone Toshimasa, et al. Concordance of Cancer Screening Attendance Among Spouse Couples: A Cross‐Sectional Survey of the Tohoku Medical Megabank Project. Psycho-Oncology. 2025; 34 (5): . doi:10.1002/pon.70158  
40.   Wang Hongxin, Iwama Noriyuki, Yuwaki Keiichi, et al. Association of Parity with Type 2 Diabetes Mellitus in Japan. Reproductive Sciences. 2025; 32 (2): 366-381. doi:10.1007/s43032-024-01752-z  
41.   Kawaguchi Chikana, Ishikuro Mami, Saito Ryota, et al. Maternal Fasting Plasma Glucose Level in Early Gestation and Developmental Delay in 2-year-old Children. The Journal of Clinical Endocrinology & Metabolism. 2025; : . doi:10.1210/clinem/dgae825  
42.   Izumi Seiya, Nishimura Misato, Iwama Noriyuki, et al. Pregnancy and Postpartum Trends in Self‐Measured Blood Pressure and Derived Indices: The BOSHI Study. The Journal of Clinical Hypertension. 2025; 27 (1): . doi:10.1111/jch.14949  
43.   Sawane Kento, Takahashi Ippei, Ishikuro Mami, et al. Association Between Human Milk Oligosaccharides and Early Adiposity Rebound in Children: A Case–Control Study of the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Journal of Nutrition. 2025; : . doi:10.1016/j.tjnut.2025.02.024  
44.   Shinoda Genki, Matsuzaki Fumiko, Ueno Fumihiko, et al. Impact of Telework on Health and Lifestyle Changes During the COVID-19 Pandemic in Japan. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J014. doi:10.1620/tjem.2025.J014  
45.   Mori Naoko, Mugikura Shunji, Hozawa Atsushi, et al. Language Registration-Based Scoring System for Handwritten Logical Memory of Wechsler Memory Scale-Revised: Developed and Validated in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2025; : 2025.J006. doi:10.1620/tjem.2025.J006  
46.   Shimoda Yoshiteru, Shibahara Ichiyo, Kanamori Masayuki, et al. Clinical Effect of Ventricular Entry During Resection of Isocitrate Dehydrogenase-Wildtype Glioblastoma: A Multi-Institutional Analysis. World Neurosurgery. 2025; 195 : 123643. doi:10.1016/j.wneu.2024.123643  
47.   Shimoda Yoshiteru, Kanamori Masayuki, Yamashita Shota, et al. Residual Pattern of the Hyperintense Area on T2-Weighted Magnetic Resonance Imaging After Initial Treatment Predicts the Pattern and Location of Recurrence in Patients with Newly Diagnosed Glioblastoma. World Neurosurgery. 2025; 193 : 517-532. doi:10.1016/j.wneu.2024.10.012  
48.   Chen Geng, Ishikuro Mami, Ohseto Hisashi, et al. Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Acta Obstetricia et Gynecologica Scandinavica. 2024; 103 (6): 1192-1200. doi:10.1111/aogs.14820  
49.   Ishikawa Tomofumi, Sakai Takamasa, Iwama Noriyuki, et al. Association between exposure to atypical antipsychotics during pregnancy and risk of miscarriage. Acta Psychiatrica Scandinavica. 2024; 150 (6): 562-572. doi:10.1111/acps.13755  
50.   Akaishi Tetsuya, Tarasawa Kunio, Fushimi Kiyohide, et al. Demographic profiles and risk factors for mortality in acute meningitis: A nationwide population‐based observational study. Acute Medicine & Surgery. 2024; 11 (1): . doi:10.1002/ams2.920  
51.   Mizuno Satoshi, Nagaie Satoshi, Sugawara Junichi, et al. Early prediction of hypertensive disorders of pregnancy toward preventive early intervention. AJOG Global Reports. 2024; 4 (4): 100383. doi:10.1016/j.xagr.2024.100383  
52.   Kawashima Aritomo, Kodama Kaori, Okubo Yukimune, et al. Long‐term clinical observation of patients with heterozygous KIF1A variants. American Journal of Medical Genetics Part A. 2024; 194 (10): . doi:10.1002/ajmg.a.63656  
53.   Takahashi Tsukasa, Tomita Hasumi, Hamada Hirotaka, et al. Transcatheter arterial embolization outperforms surgery in reducing blood transfusions for postpartum vulvovaginal hematoma. American Journal of Obstetrics and Gynecology. 2024; 231 (6): 653.e1-653.e8. doi:10.1016/j.ajog.2024.03.016  
54.   Mino Masaaki, Kakazu Eiji, Sano Akitoshi, et al. Comprehensive analysis of peripheral blood free amino acids in MASLD: the impact of glycine-serine-threonine metabolism. Amino Acids. 2024; 57 (1): 3. doi:10.1007/s00726-024-03433-2  
55.   Chu Ching-Tung, Uruno Akira, Katsuoka Fumiki, Yamamoto Masayuki. Role of NRF2 in Pathogenesis of Alzheimer’s Disease. Antioxidants. 2024; 13 (12): 1529. doi:10.3390/antiox13121529  
56.   Hayashi Hironori, Saijo Erika, Hirata Kazushige, et al. SHIN-2 exerts potent activity against VanA-type vancomycin-resistant Enterococcus faecium in vitro by stabilizing the active site loop of serine hydroxymethyltransferase. Archives of Biochemistry and Biophysics. 2024; 761 : 110160. doi:10.1016/j.abb.2024.110160  
57.   Yamazaki Shuki, Hishinuma Eiji, Suzuki Yuma, et al. Functional significance of CYP2B6 gene rare allelic variants identified in Japanese individuals. Biochemical Pharmacology. 2024; 229 : 116515. doi:10.1016/j.bcp.2024.116515  
58.   Kato Koichi, Nakayoshi Tomoki, Hioki Sho, et al. Structural Impact Assessment of Cytochrome P450 2A13 Polymorphisms Using Molecular Dynamics Simulations. Biological and Pharmaceutical Bulletin. 2024; 47 (3): b23-00908. doi:10.1248/bpb.b23-00908  
59.   Yoshida Yuki, Niimi Yushi, Fushihara Daichi, et al. 2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants. Bioorganic & Medicinal Chemistry. 2024; 110 : 117813. doi:10.1016/j.bmc.2024.117813  
60.   Omori Satoshi, Hanazono Yuya, Nishi Hafumi, Kinoshita Kengo. The role of the STAS domain in SLC26A9 for chloride ion transporter function. Biophysical Journal. 2024; 123 (12): 1751-1762. doi:10.1016/j.bpj.2024.05.018  
61.   Kudo Hisaaki, Ishida Noriko, Nobukuni Takahiro, et al. Detection and Correction of Sample Misidentifications in a Biobank Using the MassARRAY System and Genomic Information. Biopreservation and Biobanking. 2024; 22 (4): 373-382. doi:10.1089/bio.2022.0211  
62.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between leisure time, non-leisure time physical activity, and kidney function in Japanese adults: a cross-sectional study. BMC Nephrology. 2024; 25 (1): 354. doi:10.1186/s12882-024-03813-6  
63.   Wang Hongxin, Iwama Noriyuki, Yuwaki Keiichi, et al. Relationship between parity and the prevalence of chronic kidney disease in Japan considering hypertensive disorders of pregnancy and body mass index. BMC Nephrology. 2024; 25 (1): 166. doi:10.1186/s12882-024-03604-z  
64.   Yonezawa Yudai, Takahashi Ippei, Ohseto Hisashi, et al. Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2024; 24 (1): 209. doi:10.1186/s12884-024-06376-4  
65.   Noji Yoshiaki, Hatanaka Rieko, Nakaya Naoki, et al. Association of physiological factors with grip and leg extension strength: tohoku medical megabank community-based cohort study. BMC Public Health. 2024; 24 (1): 714. doi:10.1186/s12889-024-18244-z  
66.   Akiyama Tomoyuki, Saigusa Daisuke, Inoue Takushi, et al. Exploration of urine metabolic biomarkers for new-onset, untreated pediatric epilepsy: A gas and liquid chromatography mass spectrometry-based metabolomics study. Brain and Development. 2024; 46 (4): 180-186. doi:10.1016/j.braindev.2023.12.004  
67.   Shiraishi Kouya, Takahashi Atsushi, Momozawa Yukihide, et al. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses. Cancer Communications. 2024; 44 (2): 287-293. doi:10.1002/cac2.12498  
68.   Iwasaki Tomoyuki, Shirota Hidekazu, Sasaki Keiju, et al. Specific cancer types and prognosis in patients with variations in the KEAP1NRF2 system: A retrospective cohort study. Cancer Science. 2024; 115 (12): 4034-4044. doi:10.1111/cas.16355  
69.   Ito Shin, Ando Mika, Aoki Shuichi, et al. Usefulness of multigene liquid biopsy of bile for identifying driver genes of biliary duct cancers. Cancer Science. 2024; 115 (12): 4054-4063. doi:10.1111/cas.16365  
70.   Takahashi Jun, Suzuki Takafumi, Sato Miu, et al. Differential squamous cell fates elicited by NRF2 gain of function versus KEAP1 loss of function. Cell Reports. 2024; 43 (4): 114104. doi:10.1016/j.celrep.2024.114104  
71.   Inose-Maruyama Atsushi, Irokawa Hayato, Takeda Kouki, et al. Bag1 protein loss sensitizes mouse embryonic fibroblasts to glutathione depletion. Cell Stress and Chaperones. 2024; 29 (3): 497-509. doi:10.1016/j.cstres.2024.05.003  
72.   Matsuda Kenichi, Niikura Shinya, Ichihara Rintaro, et al. Synthesis and Cytotoxicity of Cyclic Octapeptide Surugamides with Varied N-Acyl Moieties. Chemical and Pharmaceutical Bulletin. 2024; 72 (9): c24-00533. doi:10.1248/cpb.c24-00533  
73.   Nakane Keita, Fujimura Chizu, Miyano Shogo, et al. Laccase-catalyzed tyrosine click reaction with 1-methyl-4-arylurazole: rapid labeling on protein surfaces. Chemical Communications. 2024; 60 (96): 14208-14211. doi:10.1039/D4CC03802A  
74.   Yamaki Keiko, Tamahara Toru, Washio Jumpei, et al. Intracanal microbiome profiles of two apical periodontitis cases in one patient: A comparison with saliva and plaque profiles. Clinical and Experimental Dental Research. 2024; 10 (2): . doi:10.1002/cre2.862  
75.   Ikejiri Kazuaki, Suzuki Takafumi, Muto Satsuki, et al. Effects of NRF2 polymorphisms on safety and efficacy of bardoxolone methyl: subanalysis of TSUBAKI study. Clinical and Experimental Nephrology. 2024; 28 (3): 225-234. doi:10.1007/s10157-023-02427-w  
76.   Abe Michiaki, Yamaguchi Takuhiro, Koshiba Seizo, et al. Oral alkalinizing supplementation suppressed intrarenal reactive oxidative stress in mild-stage chronic kidney disease: a randomized cohort study. Clinical and Experimental Nephrology. 2024; 28 (11): 1134-1154. doi:10.1007/s10157-024-02517-3  
77.   Takayama Jun, Makino Satoshi, Funayama Takamitsu, et al. A fine‐scale genetic map of the Japanese population. Clinical Genetics. 2024; 106 (3): 284-292. doi:10.1111/cge.14536  
78.   Hiromoto Kana, Yamada Takahiro, Tsuchiya Mio, et al. Difficulties in disclosing secondary findings by facilities performing comprehensive germline genetic testing for rare diseases in Japan. Congenital Anomalies. 2024; 64 (3): 116-124. doi:10.1111/cga.12562  
79.   Obara Taku. Directions for perinatal pharmacoepidemiology studies in Japan. Congenital Anomalies. 2024; 64 (1): 4-5. doi:10.1111/cga.12549  
80.   Akaishi Tetsuya, Nakaya Kumi, Nakaya Naoki, et al. Low Hemoglobin Level and Elevated Inflammatory Hematological Ratios Associated With Depression and Sleep Disturbance. Cureus. 2024; : . doi:10.7759/cureus.56621  
81.   Ohseto Hisashi, Takahashi Ippei, Narita Akira, et al. Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory. Depression and Anxiety. 2024; 2024 : 1-13. doi:10.1155/2024/6622666  
82.   Hashimoto Hideaki, Satoh Michihiro, Nakayama Shingo, et al. Comparison of renal prognosis between dipeptidyl peptidase‐4 inhibitor users and non‐users. Diabetes, Obesity and Metabolism. 2024; 26 (10): 4460-4467. doi:10.1111/dom.15800  
83.   Tanabe Hayato, Sato Masahiro, Miyake Akimitsu, et al. Machine learning-based reproducible prediction of type 2 diabetes subtypes. Diabetologia. 2024; 67 (11): 2446-2458. doi:10.1007/s00125-024-06248-8  
84.   Mori Yu, Ren Hainan, Mori Naoko, et al. Magnetic Resonance Imaging Texture Analysis Based on Intraosseous and Extraosseous Lesions to Predict Prognosis in Patients with Osteosarcoma. Diagnostics. 2024; 14 (22): 2562. doi:10.3390/diagnostics14222562  
85.   Ogata Yohei, Hatta Waku, Koike Tomoyuki, et al. Is blue light imaging without magnification satisfactory as screening for esophageal squamous cell carcinoma? Post‐hoc analysis of multicenter randomized controlled trial. Digestive Endoscopy. 2024; : . doi:10.1111/den.14788  
86.   Tanaka Ippei, Hatta Waku, Koike Tomoyuki, et al. Risk factors and pattern of metastatic recurrence after endoscopic resection with additional treatment for esophageal cancer. Diseases of the Esophagus. 2024; 37 (11): . doi:10.1093/dote/doae048  
87.   石黒 真美, 小原 拓, 黒田 真帆, et al. 東北メディカル・メガバンク計画三世代コホート調査:10年間の取り組みと周産期転帰のプロファイル. DOHaD研究. 2024; 12 (1): 11-17. doi:10.51067/dohad.12.1_11  
88.   Shimizu Makiko, Makiguchi Miaki, Hishinuma Eiji, et al. Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources. Drug Metabolism and Pharmacokinetics. 2024; 55 : 100539. doi:10.1016/j.dmpk.2023.100539  
89.   Noda Aoi, Obara Taku, Matsuzaki Fumiko, et al. Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy. Drugs - Real World Outcomes. 2024; 11 (2): 263-272. doi:10.1007/s40801-023-00411-0  
90.   Tokunaga Misaki, Kikuchi Daisuke, Noda Aoi, et al. Trends in Anti-Influenza Drug Prescription and Adverse Drug Reaction Reporting After the Lifting of Oseltamivir Prescribing Restrictions in Pediatric Outpatients: An Ecological Study Using the MDV Analyzer® And the Japanese Adverse Drug Event Report Datab. Drugs - Real World Outcomes. 2024; 11 (2): 177-184. doi:10.1007/s40801-023-00414-x  
91.   Izumi Seiya, Iwama Noriyuki, Hamada Hirotaka, et al. Associations of fasting plasma glucose and glycosylated hemoglobin levels at less than 24 weeks of gestation with hypertensive disorders of pregnancy: the BOSHI study. Endocrine Journal. 2024; 71 (10): EJ23-0568. doi:10.1507/endocrj.EJ23-0568  
92.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal social isolation and behavioral problems in preschool children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Child & Adolescent Psychiatry. 2024; 33 (3): 761-769. doi:10.1007/s00787-023-02199-4  
93.   Noda Aoi, Obara Taku, Shirota Matsuyuki, et al. Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Pharmacology. 2024; 80 (8): 1171-1180. doi:10.1007/s00228-024-03685-7  
94.   Mori Naoko, Mugikura Shunji. Ai-based algorithm for measurement of the thoracic aortic diameter in low-dose chest CT: Prospects from cross-sectional to longitudinal assessment. European Journal of Radiology. 2024; 179 : 111660. doi:10.1016/j.ejrad.2024.111660  
95.   Tawarayama Hiroshi, Uchida Keiko, Hasegawa Hirokazu, et al. Estrogen, via ESR2 receptor, prevents oxidative stress-induced Müller cell death and stimulates FGF2 production independently of NRF2, attenuating retinal degeneration. Experimental Eye Research. 2024; 248 : 110103. doi:10.1016/j.exer.2024.110103  
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