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  • 2019 major update of Japanese Multi Omics Reference Panel "jMorp":15,000 people metabolome data and 4.7K Japanese individual genome variation [Press Release]
  • 2019 major update of Japanese Multi Omics Reference Panel "jMorp":15,000 people metabolome data and 4.7K Japanese individual genome variation [Press Release]

    Research: 2019/09/13


    Tohoku Medical Megabank Organization (ToMMo) performed a major update of the database, Japanese Multi Omics Reference Panel "jMorp", on September 2nd, 2019. The database has several sections such as metabolome, genome variation, or genome sequence. This time, we updated metabolome section and genome variation section.

    Update Details
    Metabolome

    We released distributions of concentrations about 43 metabolites identified by NMR in 15,403 volunteers, distributions of peak intensities of 168 characterized metabolites by GC-MS in 2,270 volunteers. We also released the quantified metabolome data from 1,493 volunteers by Biocrates LC-MS analysis. Moreover, information of metabolome data obtained from volunteers in repeat assessment survey and difference of metabolome during pregnancy in baseline assessment survey is firstly released.

    Genome Variation

    We released 4.7KJPN, allele and genotype frequency panel from 4,773 Japanese individuals. 4.7KJPN is involved people from several regions in Japan where outside of Tohoku region, so it is more highly represent as Japanese genome variation.

     

    ・Number of SNV and INDEL in 4.7KJPN

      SNV INDEL
    Total New Total New
    Autosome 59,199,967 24,949,665 8,238,823 4,543,503
    X chromosome*
    (PAR1+PAR2)
    2,316,891 1,051,758 341,289 191,811
    X chromosome *
    (PAR1+PAR2+XTR)
    2,318,572 1,052,789 341,547 191,915
    Mitochondria 2,801 1,381    

    * Tadaka Shu, et al. 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. Human Genome Variation. 2019; 6 (1): 28. doi:10.1038/s41439-019-0059-5

     

    How to use jMorp

    Please refer to the link below.
    https://jmorp.megabank.tohoku.ac.jp/201808/help/tutorial/#genome

     

    Related Link

    New article about 3.5KJPNv2 was published (2019/07/04)

    New version of Japanese Multi Omics Reference Panel "jMorp": 10,719 people Metabolome data are now available online (2018/09/06)

    Expanded version of Japanese genome reference panel including INDEL allele is available online (2019/01/15)


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