| 1. | Ikejiri Kazuaki, Suzuki Takafumi, Muto Satsuki, et al. Effects of NRF2 polymorphisms on safety and efficacy of bardoxolone methyl: subanalysis of TSUBAKI study. Clinical and Experimental Nephrology. 2024; 28 (3): 225-234. doi:10.1007/s10157-023-02427-w | ||
| 2. | Tadaka Shu, Kawashima Junko, Hishinuma Eiji, et al. jMorp: Japanese Multi-Omics Reference Panel update report 2023. Nucleic Acids Research. 2024; 52 (D1): D622-D632. doi:10.1093/nar/gkad978 | ||
| 3. | Aoki Yu-ichi, Taguchi Keiko, Anzawa Hayato, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. The Journal of Biochemistry. 2024; : . doi:10.1093/jb/mvae008 | ||
| 4. | Hirose Wataru, Horiuchi Makoto, Li Donghan, et al. Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium. Cellular and Molecular Gastroenterology and Hepatology. 2023; 15 (1): 153-178. doi:10.1016/j.jcmgh.2022.09.004 | ||
| 5. | Shimizu Ritsuko, Hirano Ikuo, Hasegawa Atsushi, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Communications Biology. 2023; 6 (1): 875. doi:10.1038/s42003-023-05251-w | ||
| 6. | Tatara Yota, Yamazaki Hiromi, Katsuoka Fumiki, et al. Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment. Current Research in Translational Medicine. 2023; 71 (1): 103367. doi:10.1016/j.retram.2022.103367 | ||
| 7. | Saito-Hakoda Akiko, Kikuchi Atsuo, Takahashi Tadahisa, et al. Familial Paget’s disease of bone with ocular manifestations and a novel TNFRSF11A duplication variant (72dup27). Journal of Bone and Mineral Metabolism. 2023; 41 (2): 193-202. doi:10.1007/s00774-022-01392-w | ||
| 8. | Otsuki Akihito, Okamura Yasunobu, Ishida Noriko, et al. Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology. Communications Biology. 2022; 5 (1): 991. doi:10.1038/s42003-022-03953-1 | ||
| 9. | Katsuoka Fumiki, Otsuki Akihito, Hatanaka Nozomi, et al. Target Gene Diversity of the Nrf1-MafG Transcription Factor Revealed by a Tethered Heterodimer. Molecular and Cellular Biology. 2022; 42 (3): 1-18. doi:10.1128/mcb.00520-21 | ||
| 10. | Kuga Ayumi, Tsuchida Kouhei, Panda Harit, et al. The β -TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation In Vivo. Molecular and Cellular Biology. 2022; 42 (7): 1-22. doi:10.1128/mcb.00563-21 | ||
| 11. | Fuse Nobuo, Sakurai Miyuki, Motoike Ikuko N., et al. Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan. Ophthalmology Science. 2022; 2 (1): 100113. doi:10.1016/j.xops.2022.100113 | ||
| 12. | Okazaki Keito, Anzawa Hayato, Katsuoka Fumiki, et al. CEBPB is required for NRF2-mediated drug resistance in NRF2-activated non-small cell lung cancer cells. The Journal of Biochemistry. 2022; 171 (5): 567-578. doi:10.1093/jb/mvac013 | ||
| 13. | Tayama Hodaka, Karasawa Hideaki, Yamamura Akihiro, et al. The association between ERK inhibitor sensitivity and molecular characteristics in colorectal cancer. Biochemical and Biophysical Research Communications. 2021; 560 : 59-65. doi:10.1016/j.bbrc.2021.04.130 | ||
| 14. | Yamada Mitsuhiro, Motoike Ikuko N., Kojima Kaname, et al. Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator. Communications Biology. 2021; 4 (1): 1288. doi:10.1038/s42003-021-02813-8 | ||
| 15. | Uruno Akira, Saigusa Daisuke, Suzuki Takafumi, et al. Nrf2 plays a critical role in the metabolic response during and after spaceflight. Communications Biology. 2021; 4 (1): 1381. doi:10.1038/s42003-021-02904-6 | ||
| 16. | Ogishima Soichi, Nagaie Satoshi, Mizuno Satoshi, et al. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Human Genome Variation. 2021; 8 (1): 44. doi:10.1038/s41439-021-00175-5 | ||
| 17. | Shido Kosuke, Kojima Kaname, Shirota Matsuyuki, et al. GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals. Journal of Investigative Dermatology. 2021; 141 (11): 2749-2752. doi:10.1016/j.jid.2021.02.762 | ||
| 18. | Otsuki Akihito, Okamura Yasunobu, Aoki Yuichi, et al. Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis. Molecular and Cellular Biology. 2021; 41 (2): 1-18. doi:10.1128/MCB.00472-20 | ||
| 19. | Takayama Jun, Tadaka Shu, Yano Kenji, et al. Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. Nature Communications. 2021; 12 (1): 226. doi:10.1038/s41467-020-20146-8 | ||
| 20. | Tadaka Shu, Hishinuma Eiji, Komaki Shohei, et al. jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population. Nucleic Acids Research. 2021; 49 (D1): D536-D544. doi:10.1093/nar/gkaa1034 | ||
| 21. | Tokunaga Hideki, Iida Keita, Hozawa Atsushi, et al. Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2). PLOS ONE. 2021; 16 (1): e0236907. doi:10.1371/journal.pone.0236907 | ||
| 22. | Onoki Takahiro, Izumi Yoshihiro, Takahashi Masatomo, et al. Skeletal muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice. Redox Biology. 2021; 43 : 101966. doi:10.1016/j.redox.2021.101966 | ||
| 23. | Nagayoshi Y., Chujo T., Hirata S., et al. Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability. Science Advances. 2021; 7 (13): eabf3072. doi:10.1126/sciadv.abf3072 | ||
| 24. | Saigusa Daisuke, Motoike Ikuko N., Saito Sakae, et al. Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites. Cancer Science. 2020; 111 (2): 667-678. doi:10.1111/cas.14278 | ||
| 25. | Koshiba Seizo, Motoike Ikuko N., Saigusa Daisuke, et al. Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population. Communications Biology. 2020; 3 (1): 662. doi:10.1038/s42003-020-01383-5 | ||
| 26. | Suzuki Takafumi, Uruno Akira, Yumoto Akane, et al. Nrf2 contributes to the weight gain of mice during space travel. Communications Biology. 2020; 3 (1): 496. doi:10.1038/s42003-020-01227-2 | ||
| 27. | Ishida Noriko, Aoki Yuichi, Katsuoka Fumiki, et al. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. Free Radical Biology and Medicine. 2020; 161 : 71-83. doi:10.1016/j.freeradbiomed.2020.09.023 | ||
| 28. | Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169 | ||
| 29. | Shirota Matsuyuki, Saigusa Daisuke, Yamashita Riu, et al. Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy. Medical Mass Spectrometry. 2020; 4 (1): 36-49. doi:10.24508/mms.2020.06.001 | ||
| 30. | Okazaki Keito, Anzawa Hayato, Liu Zun, et al. Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. Nature Communications. 2020; 11 (1): 5911. doi:10.1038/s41467-020-19593-0 | ||
| 31. | Lin Yingsong, Nakatochi Masahiro, Hosono Yasuyuki, et al. Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Nature Communications. 2020; 11 (1): 3175. doi:10.1038/s41467-020-16711-w | ||
| 32. | Kojima Kaname, Tadaka Shu, Katsuoka Fumiki, et al. A genotype imputation method for de-identified haplotype reference information by using recurrent neural network. PLOS Computational Biology. 2020; 16 (10): e1008207. doi:10.1371/journal.pcbi.1008207 | ||
| 33. | Nishizawa Ayako, Kumada Kazuki, Tateno Keiko, et al. Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia. Scientific Reports. 2020; 10 (1): 20027. doi:10.1038/s41598-020-77081-3 | ||
| 34. | Keleku-Lukwete Nadine, Suzuki Mikiko, Panda Harit, et al. Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice. Blood Advances. 2019; 3 (8): 1285-1297. doi:10.1182/bloodadvances.2018017574 | ||
| 35. | Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): e025939. doi:10.1136/bmjopen-2018-025939 | ||
| 36. | Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7 | ||
| 37. | Tadaka Shu, Katsuoka Fumiki, Ueki Masao, et al. 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. Human Genome Variation. 2019; 6 (1): 28. doi:10.1038/s41439-019-0059-5 | ||
| 38. | Nagasaki Masao, Kuroki Yoko, Shibata Tomoko F., et al. Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. Human Genome Variation. 2019; 6 (1): 27. doi:10.1038/s41439-019-0057-7 | ||
| 39. | Fuse Nobuo, Sakurai-Yageta Mika, Katsuoka Fumiki, et al. Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project. JMA Journal. 2019; 2 (2): 113-122. doi:10.31662/jmaj.2019-0014 | ||
| 40. | Katsuoka Fumiki, Otsuki Akihito, Takahashi Mizue, et al. Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells. Molecular and Cellular Biology. 2019; 39 (20): . doi:10.1128/MCB.00273-19 | ||
| 41. | Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096 | ||
| 42. | Dodo Mina, Kitamura Hiroshi, Shima Hiroki, et al. Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A. The Journal of Biochemistry. 2019; 165 (4): 323-334. doi:10.1093/jb/mvy108 | ||
| 43. | Mimori Takahiro, Yasuda Jun, Kuroki Yoko, et al. Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing. The Pharmacogenomics Journal. 2019; 19 (2): 136-146. doi:10.1038/s41397-017-0010-4 | ||
| 44. | Minegishi Naoko, Nishijima Ichiko, Nobukuni Takahiro, et al. Biobank Establishment and Sample Management in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2019; 248 (1): 45-55. doi:10.1620/tjem.248.45 | ||
| 45. | Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0 | ||
| 46. | Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588 | ||
| 47. | Shibuya Yusuke, Tokunaga Hideki, Saito Sakae, et al. Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing. Genes, Chromosomes and Cancer. 2018; 57 (2): 51-60. doi:10.1002/gcc.22507 | ||
| 48. | Yamaguchi-Kabata Yumi, Yasuda Jun, Tanabe Osamu, et al. Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals. Journal of Human Genetics. 2018; 63 (2): 213-230. doi:10.1038/s10038-017-0347-1 | ||
| 49. | Sekine Hiroki, Okazaki Keito, Kato Koichiro, et al. O -GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1. Molecular and Cellular Biology. 2018; 38 (17): . doi:10.1128/MCB.00252-18 | ||
| 50. | Nishioka Masaki, Bundo Miki, Ueda Junko, et al. Identification of somatic mutations in postmortem human brains by whole genome sequencing and their implications for psychiatric disorders. Psychiatry and Clinical Neurosciences. 2018; 72 (4): 280-294. doi:10.1111/pcn.12632 | ||
| 51. | 山本 雅之, 勝岡 史城. 東北メディカル・メガバンク計画が実施するゲノムコホート研究. 医学のあゆみ. 2018; 266 ((5)): 370-376. | ||
| 52. | Katayama Saori, Suzuki Mikiko, Yamaoka Ayaka, et al. GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. Blood. 2017; 130 (7): 908-919. doi:10.1182/blood-2016-12-756767 | ||
| 53. | Pan Xiaoqing, Nariai Naoki, Fukuhara Noriko, et al. Monitoring of minimal residual disease in early T‐cell precursor acute lymphoblastic leukaemia by next‐generation sequencing. British Journal of Haematology. 2017; 176 (2): 318-321. doi:10.1111/bjh.13948 | ||
| 54. | Tsuchida Kouhei, Tsujita Tadayuki, Hayashi Makiko, et al. Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation. Free Radical Biology and Medicine. 2017; 103 : 236-247. doi:10.1016/j.freeradbiomed.2016.12.041 | ||
| 55. | Matsuura Kentaro, Sawai Hiromi, Ikeo Kazuho, et al. Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. Gastroenterology. 2017; 152 (6): 1383-1394. doi:10.1053/j.gastro.2017.01.041 | ||
| 56. | Hamanaka Teruhiko, Kimura Masae, Sakurai Tetsuro, et al. A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients. Investigative Opthalmology & Visual Science. 2017; 58 (5): 2818. doi:10.1167/iovs.16-20646 | ||
| 57. | Yu Lei, Takai Jun, Otsuki Akihito, et al. Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis. Molecular and Cellular Biology. 2017; 37 (8): MCB.00592-16. doi:10.1128/MCB.00592-16 | ||
| 58. | Hachiya Tsuyoshi, Furukawa Ryohei, Shiwa Yuh, et al. Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies. npj Genomic Medicine. 2017; 2 (1): 11. doi:10.1038/s41525-017-0016-5 | ||
| 59. | Otsuki Akihito, Suzuki Mikiko, Katsuoka Fumiki, et al. Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection. Free Radical Biology and Medicine. 2016; 91 : 45-57. doi:10.1016/j.freeradbiomed.2015.12.005 | ||
| 60. | Katsuoka Fumiki, Yamamoto Masayuki. Small Maf proteins (MafF, MafG, MafK): History, structure and function. Gene. 2016; 586 (2): 197-205. doi:10.1016/j.gene.2016.03.058 | ||
| 61. | Katsuoka Fumiki, Yamazaki Hiromi, Yamamoto Masayuki. Small Maf deficiency recapitulates the liver phenotypes of Nrf1- and Nrf2-deficient mice. Genes to Cells. 2016; 21 (12): 1309-1319. doi:10.1111/gtc.12445 | ||
| 62. | Uruno Akira, Yagishita Yoko, Katsuoka Fumiki, et al. Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism. Molecular and Cellular Biology. 2016; 36 (11): 1655-1672. doi:10.1128/MCB.01095-15 | ||
| 63. | Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463 | ||
| 64. | Tsujita Tadayuki, Baird Liam, Furusawa Yuki, et al. Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system. Genes to Cells. 2015; 20 (7): 563-577. doi:10.1111/gtc.12248 | ||
| 65. | Yamaguchi-Kabata Yumi, Nariai Naoki, Kawai Yosuke, et al. iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing. Human Genome Variation. 2015; 2 (1): 15050. doi:10.1038/hgv.2015.50 | ||
| 66. | Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature Communications. 2015; 6 (1): 8018. doi:10.1038/ncomms9018 | ||
| 67. | Nishikawa Keizo, Iwamoto Yoriko, Kobayashi Yasuhiro, et al. DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway. Nature Medicine. 2015; 21 (3): 281-287. doi:10.1038/nm.3774 | ||
| 68. | Katsuoka Fumiki, Yokozawa Junji, Tsuda Kaoru, et al. An efficient quantitation method of next-generation sequencing libraries by using MiSeq sequencer. Analytical Biochemistry. 2014; 466 (466C): 27-29. doi:10.1016/j.ab.2014.08.015 | ||
| 69. | Motoike Ikuko N, Matsumoto Mitsuyo, Danjoh Inaho, et al. Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population. BMC Genomics. 2014; 15 (1): 673. doi:10.1186/1471-2164-15-673 | ||
| 70. | Hirotsu Yosuke, Higashi Chika, Fukutomi Toshiaki, et al. Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice. Genes to Cells. 2014; 19 (8): 650-665. doi:10.1111/gtc.12165 | ||
| 71. | 布施 昇男、清水 愛、木村 雅恵、高野 良真、石 棟、宮澤 晃子、国松 志保、劉 孟林、渡邊 亮、安田 正幸、横山 悠、檜森 紀子、津田 聡、山本 耕太郎、中澤 徹、安田 純、勝岡 史城、小島 要、成相 直樹、松本 光代、元池 育子、長崎 正朗、木下 賢吾、五十嵐 和彦、山本 雅之、新堀 哲也、青木 洋子、松原 洋一、舟山 亮、長嶋 剛史、中山 啓子、眞島 行彦、舟山 智代、田中 光一、原田 高幸、阿部 春樹、福地 健郎、安田 典子、出田 秀尚、鄭 暁東、白石 敦、大橋 祐一、石田 誠夫、原 岳、金森 章. 緑内障のゲノム解析―次世代医療•個別化医療に向けて. 日本眼科学会雑誌. 2013; 118 ((3)): 216-240. | ||
| 72. | Hirotsu Yosuke, Katsuoka Fumiki, Funayama Ryo, et al. Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks. Nucleic Acids Research. 2012; 40 (20): 10228-10239. doi:10.1093/nar/gks827 |