Tohoku University Tohoku Medical Megabank Organization
2024.04.24

1.   Chen Geng, Ishikuro Mami, Ohseto Hisashi, et al. Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. Acta Obstetricia et Gynecologica Scandinavica. 2024; : . doi:10.1111/aogs.14820  
2.   Yonezawa Yudai, Takahashi Ippei, Ohseto Hisashi, et al. Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2024; 24 (1): 209. doi:10.1186/s12884-024-06376-4  
3.   Noji Yoshiaki, Hatanaka Rieko, Nakaya Naoki, et al. Association of physiological factors with grip and leg extension strength: tohoku medical megabank community-based cohort study. BMC Public Health. 2024; 24 (1): 714. doi:10.1186/s12889-024-18244-z  
4.   Akiyama Tomoyuki, Saigusa Daisuke, Inoue Takushi, et al. Exploration of urine metabolic biomarkers for new-onset, untreated pediatric epilepsy: A gas and liquid chromatography mass spectrometry-based metabolomics study. Brain and Development. 2024; 46 (4): 180-186. doi:10.1016/j.braindev.2023.12.004  
5.   Shiraishi Kouya, Takahashi Atsushi, Momozawa Yukihide, et al. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses. Cancer Communications. 2024; 44 (2): 287-293. doi:10.1002/cac2.12498  
6.   Ikejiri Kazuaki, Suzuki Takafumi, Muto Satsuki, et al. Effects of NRF2 polymorphisms on safety and efficacy of bardoxolone methyl: subanalysis of TSUBAKI study. Clinical and Experimental Nephrology. 2024; 28 (3): 225-234. doi:10.1007/s10157-023-02427-w  
7.   Ohseto Hisashi, Takahashi Ippei, Narita Akira, et al. Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory. Depression and Anxiety. 2024; 2024 : 1-13. doi:10.1155/2024/6622666  
8.   Shimizu Makiko, Makiguchi Miaki, Hishinuma Eiji, et al. Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources. Drug Metabolism and Pharmacokinetics. 2024; 55 : 100539. doi:10.1016/j.dmpk.2023.100539  
9.   Noda Aoi, Obara Taku, Matsuzaki Fumiko, et al. Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy. Drugs - Real World Outcomes. 2024; : . doi:10.1007/s40801-023-00411-0  
10.   Tokunaga Misaki, Kikuchi Daisuke, Noda Aoi, et al. Trends in Anti-Influenza Drug Prescription and Adverse Drug Reaction Reporting After the Lifting of Oseltamivir Prescribing Restrictions in Pediatric Outpatients: An Ecological Study Using the MDV Analyzer® And the Japanese Adverse Drug Event Report Datab. Drugs - Real World Outcomes. 2024; : . doi:10.1007/s40801-023-00414-x  
11.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal social isolation and behavioral problems in preschool children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Child & Adolescent Psychiatry. 2024; 33 (3): 761-769. doi:10.1007/s00787-023-02199-4  
12.   Noda Aoi, Obara Taku, Shirota Matsuyuki, et al. Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Pharmacology. 2024; : . doi:10.1007/s00228-024-03685-7  
13.   Tokutomi Tomoharu, Yoshida Akiko, Fukushima Akimune, et al. The Health History of First-Degree Relatives’ Dyslipidemia Can Affect Preferences and Intentions following the Return of Genomic Results for Monogenic Familial Hypercholesterolemia. Genes. 2024; 15 (3): 384. doi:10.3390/genes15030384  
14.   Kowalik Marta Anna, Taguchi Keiko, Serra Marina, et al. Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes. Hepatology. 2024; 79 (4): 829-843. doi:10.1097/HEP.0000000000000568  
15.   Akaishi Tetsuya, Tarasawa Kunio, Hamada Hirotaka, et al. Prenatal hypertension as the risk of eclampsia, HELLP syndrome, and critical obstetric hemorrhage. Hypertension Research. 2024; 47 (2): 455-466. doi:10.1038/s41440-023-01511-8  
16.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study. Hypertension Research. 2024; : . doi:10.1038/s41440-024-01582-1  
17.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. The association between blood pressure control in women during pregnancy and adverse perinatal outcomes: the TMM BirThree Cohort Study. Hypertension Research. 2024; : . doi:10.1038/s41440-023-01570-x  
18.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center. Hypertension Research. 2024; 47 (3): 586-597. doi:10.1038/s41440-023-01484-8  
19.   Satoh Michihiro, Muroya Tomoko, Murakami Takahisa, et al. The impact of clinical inertia on uncontrolled blood pressure in treated hypertension: real-world, longitudinal data from Japan. Hypertension Research. 2024; 47 (3): 598-607. doi:10.1038/s41440-023-01452-2  
20.   Yamada Mitsuhiro, Takase Masato, Nakaya Kumi, et al. FeNO distribution and its relevant factors in the general adult population and its 'healthy' subpopulation. Journal of Allergy and Clinical Immunology: Global. 2024; : 100253. doi:10.1016/j.jacig.2024.100253  
21.   Tsubota-Utsugi Megumi, Satoh Michihiro, Watanabe Jun, et al. Association between an Antioxidant-Rich Japanese Diet and Chronic Kidney Disease: The Ohasama Study. Journal of Atherosclerosis and Thrombosis. 2024; 31 (4): 64423. doi:10.5551/jat.64423  
22.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2024; : 64535. doi:10.5551/jat.64535  
23.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Combined Fat Mass and Fat-free Mass Indices and Lung Function Among Japanese Population: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2024; 34 (3): JE20220355. doi:10.2188/jea.JE20220355  
24.   Hozawa Atsushi, Nakaya Kumi, Nakaya Naoki, et al. Progress report of the Tohoku Medical Megabank Community-Based Cohort Study: Study profile of the repeated center-based survey during second period in Miyagi Prefecture. Journal of Epidemiology. 2024; : JE20230241. doi:10.2188/jea.JE20230241  
25.   Harada Sei, Iida Miho, Miyagawa Naoko, et al. Study Profile of the Tsuruoka Metabolomics Cohort Study (TMCS). Journal of Epidemiology. 2024; : JE20230192. doi:10.2188/jea.JE20230192  
26.   Yaoita Hisao, Kawai Eiichiro, Takayama Jun, et al. Genetic etiology of truncus arteriosus excluding 22q11.2 deletion syndrome and identification of c.1617del, a prevalent variant in TMEM260, in the Japanese population. Journal of Human Genetics. 2024; : . doi:10.1038/s10038-024-01223-y  
27.   Ishikuro Mami, Nishimura Tomoko, Iwata Hiroyoshi, et al. Association between infertility treatment and hypertensive disorders of pregnancy in the Japan Birth Cohort Consortium: a meta-analysis. Journal of Human Hypertension. 2024; 38 (2): 187-190. doi:10.1038/s41371-023-00890-2  
28.   Nakaya Kumi, Nakaya Naoki, Kogure Mana, et al. Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study. Journal of Neurogastroenterology and Motility. 2024; 30 (2): 208-219. doi:10.5056/jnm23090  
29.   Shimizu Hiroaki, Mori Naoko, Mugikura Shunji, et al. Application of Texture and Volume Model Analysis to Dedicated Axillary High-resolution 3D T2-weighted MR Imaging: A Novel Method for Diagnosing Lymph Node Metastasis in Patients with Clinically Node-negative Breast Cancer. Magnetic Resonance in Medical Sciences. 2024; 23 (2): mp.2022-0091. doi:10.2463/mrms.mp.2022-0091  
30.   Sato Mitsuharu, Hishinuma Eiji, Matsukawa Naomi, et al. Dietary habits and plasma lipid concentrations in a general Japanese population. Metabolomics. 2024; 20 (2): 34. doi:10.1007/s11306-024-02087-1  
31.   Itoh Taito, Omori Yuko, Seino Mitsuru, et al. Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms. Modern Pathology. 2024; 37 (1): 100358. doi:10.1016/j.modpat.2023.100358  
32.   Tadaka Shu, Kawashima Junko, Hishinuma Eiji, et al. jMorp: Japanese Multi-Omics Reference Panel update report 2023. Nucleic Acids Research. 2024; 52 (D1): D622-D632. doi:10.1093/nar/gkad978  
33.   Miki Atsuya, Fuse Nobuo, Fujimoto Satoko, et al. Prevalence, Associated Factors, and Inter-Eye Differences of Refractive Errors in a Population-Based Japanese Cohort: The Tohoku Medical Megabank Eye Study. Ophthalmic Epidemiology. 2024; 31 (1): 46-54. doi:10.1080/09286586.2023.2203226  
34.   Koyanagi Yuriko N., Nakatochi Masahiro, Namba Shinichi, et al. Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people. Science Advances. 2024; 10 (4): . doi:10.1126/sciadv.ade2780  
35.   Mizuno Satoshi, Wagata Maiko, Nagaie Satoshi, et al. Development of phenotyping algorithms for hypertensive disorders of pregnancy (HDP) and their application in more than 22,000 pregnant women. Scientific Reports. 2024; 14 (1): 6292. doi:10.1038/s41598-024-55914-9  
36.   Aoki Yu-ichi, Taguchi Keiko, Anzawa Hayato, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. The Journal of Biochemistry. 2024; : . doi:10.1093/jb/mvae008  
37.   Akaishi Tetsuya, Tadano Yasunori, Kimura Yoshitaka, et al. Evaluation of Statistical Approaches in Developing a Predictive Model of Severe COVID-19 during Early Phase of Pandemic with Limited Data Resources. The Tohoku Journal of Experimental Medicine. 2024; 262 (1): 2023.J090. doi:10.1620/tjem.2023.J090  
38.   小林 朋子. 小児科医と学校教諭の連携による,小児を対象とするゲノム医学普及啓発活動. 日本小児科学会雑誌. 2024; 128 (3): 453-460. https://www.jpeds.or.jp/journal/abstract/128-03.html  
39.   Ebata Akiko, Suzuki Takashi, Shoji-Harada Narumi, et al. Immunolocalization of Cytoplasmic ER in ER-negative Breast Carcinoma as a Potent Favorable Prognostic Predictor. ACTA HISTOCHEMICA ET CYTOCHEMICA. 2023; 56 (4): 23-00016. doi:10.1267/ahc.23-00016  
40.   Kobayashi Masayuki, Ishikuro Mami, Obara Taku, Kuriyama Shinichi. Weight‐for‐age z ‐scores of Japanese children using the World Health Organization Child Growth Standards. Acta Paediatrica. 2023; 112 (4): 776-778. doi:10.1111/apa.16662  
41.   Gearry Richard, Fukudo Shin, Barbara Giovanni, et al. Consumption of 2 Green Kiwifruits Daily Improves Constipation and Abdominal Comfort—Results of an International Multicenter Randomized Controlled Trial. American Journal of Gastroenterology. 2023; 118 (6): 1058-1068. doi:10.14309/ajg.0000000000002124  
42.   Nakayama Shingo, Satoh Michihiro, Metoki Hirohito, et al. Association Between Ambulatory Blood Pressure and Risk of Home Hypertension in a Normotensive Population: The Ohasama Study. American Journal of Hypertension. 2023; 36 (3): 151-158. doi:10.1093/ajh/hpac121  
43.   Hanyuda Akiko, Goto Atsushi, Nakatochi Masahiro, et al. Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population. American Journal of Ophthalmology. 2023; 245 : 193-201. doi:10.1016/j.ajo.2022.09.004  
44.   Machida Toshiya, Obara Taku, Ishikuro Mami, et al. Liver steatosis and fibrosis markers’ association with cardiovascular and renal damage in Japanese adults: the TMM BirThree cohort study. Annals of Hepatology. 2023; 28 (1): 100761. doi:10.1016/j.aohep.2022.100761  
45.   Uruno Akira, Yamamoto Masayuki. The KEAP1-NRF2 System and Neurodegenerative Diseases. Antioxidants & Redox Signaling. 2023; 38 (13-15): 974-988. doi:10.1089/ars.2023.0234  
46.   Sone Toshimasa, Nakaya Naoki, Sugawara Yumi, et al. Effect of social participation on the association between frailty and disability. Archives of Gerontology and Geriatrics. 2023; 110 : 104989. doi:10.1016/j.archger.2023.104989  
47.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal postnatal bonding disorder and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2023; 26 (2): 219-226. doi:10.1007/s00737-023-01298-0  
48.   Kumondai Masaki, Maekawa Masamitsu, Hishinuma Eiji, et al. Development of a Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analytical Method for Urinary Endogenous Substrates and Metabolites for Predicting Cytochrome P450 3A4 Activity. Biological and Pharmaceutical Bulletin. 2023; 46 (3): b22-00840. doi:10.1248/bpb.b22-00840  
49.   Kudo Hisaaki, Ishida Noriko, Nobukuni Takahiro, et al. Detection and Correction of Sample Misidentifications in a Biobank Using the MassARRAY System and Genomic Information. Biopreservation and Biobanking. 2023; : . doi:10.1089/bio.2022.0211  
50.   Hasegawa Ryoko, Saito-Nakaya Kumi, Gu Li, et al. Maternal separation and TNBS-induced gut inflammation synergistically alter the sexually differentiated stress response in rats. BioPsychoSocial Medicine. 2023; 17 (1): 7. doi:10.1186/s13030-022-00258-x  
51.   Ishikawa Tomofumi, Kawame Hiroshi, Mano Nariyasu, Obara Taku. Real‐world prevalence, time of diagnosis, and co‐occurrence patterns of birth defects in live‐born infants, 2014–2020: A health administrative database study in Japan. Birth Defects Research. 2023; 115 (18): 1723-1736. doi:10.1002/bdr2.2247  
52.   Nakai Taku, Iwamura Yuma, Kato Koichiro, et al. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice. Blood Advances. 2023; 7 (15): 3793-3805. doi:10.1182/bloodadvances.2023009798  
53.   Katayama Osamu, Lee Sangyoon, Bae Seongryu, et al. Differential effects of lifestyle activities on disability incidence based on neighborhood amenities. BMC Geriatrics. 2023; 23 (1): 483. doi:10.1186/s12877-023-04170-z  
54.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and infant birth weight: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Pregnancy and Childbirth. 2023; 23 (1): 268. doi:10.1186/s12884-023-05603-8  
55.   Maeda Yuto, Doi Satomi, Isumi Aya, et al. Association between poor parent-daughter relationships and the risk of hyperglycemia in pregnancy: a hospital-based prospective cohort study in Japan. BMC Pregnancy and Childbirth. 2023; 23 (1): 227. doi:10.1186/s12884-023-05535-3  
56.   Mizuno Satoshi, Nagaie Satoshi, Tamiya Gen, et al. Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy and Childbirth. 2023; 23 (1): 628. doi:10.1186/s12884-023-05919-5  
57.   Chiba Ippei, Takahashi Masayoshi, Lee Sangyoon, et al. Association between COVID-19 emergency declarations and physical activity among community-dwelling older adults enrolled in a physical activity measurement program: Evidence from a retrospective observational study using the regression discontinuity desig. BMC Public Health. 2023; 23 (1): 998. doi:10.1186/s12889-023-15932-0  
58.   Murakami Keiko, Aida Jun, Kuriyama Shinichi, Hashimoto Hideki. Associations of health literacy with dental care use and oral health status in Japan. BMC Public Health. 2023; 23 (1): 1074. doi:10.1186/s12889-023-15866-7  
59.   Matsuda Ayako, Asayama Kei, Obara Taku, et al. Behavioral changes of preventive activities of influenza among children in satellite cities of a metropolitan area of Tokyo, Japan, by the COVID-19 pandemic. BMC Public Health. 2023; 23 (1): 727. doi:10.1186/s12889-023-15606-x  
60.   Ishikawa Hirono, Ogawa Runa, Otsuki Aki, et al. Effect modification by geographic area on the association between health literacy and self-rated health: a nationwide cross-sectional study in Japan. BMC Public Health. 2023; 23 (1): 952. doi:10.1186/s12889-023-15897-0  
61.   Ohneda Kinuko, Hamanaka Yohei, Kawame Hiroshi, et al. Returning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants. Breast Cancer. 2023; 30 (1): 110-120. doi:10.1007/s12282-022-01404-7  
62.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling. Cancer & Metabolism. 2023; 11 (1): 16. doi:10.1186/s40170-023-00317-z  
63.   Tsuchiya Masami, Obara Taku, Kikuchi Masafumi, Mano Nariyasu. The prevalence of end-of-life chemotherapy and targeted therapy in Japan, assessed using a health claims database. Cancer Chemotherapy and Pharmacology. 2023; 91 (6): 501-506. doi:10.1007/s00280-023-04535-6  
64.   Yoshihara Kosuke, Baba Tsukasa, Tokunaga Hideki, et al. Homologous recombination inquiry through ovarian malignancy investigations: JGOG3025 Study. Cancer Science. 2023; 114 (6): 2515-2523. doi:10.1111/cas.15747  
65.   Shimizu Takanori, Iwama Noriyuki, Tokunaga Hideki, et al. Precautions during Direct Oral Anticoagulant Introduction in Gynecologic Malignancies: A Single-Center Retrospective Cohort Study. Cancers. 2023; 15 (4): 1132. doi:10.3390/cancers15041132  
66.   Hirose Wataru, Horiuchi Makoto, Li Donghan, et al. Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium. Cellular and Molecular Gastroenterology and Hepatology. 2023; 15 (1): 153-178. doi:10.1016/j.jcmgh.2022.09.004  
67.   Shinoda Genki, Nagaoka Yudai, Ueno Fumihiko, et al. Association between being Overweight in Young Childhood and during School Age and Puberty. Children. 2023; 10 (5): 909. doi:10.3390/children10050909  
68.   Shimizu Ritsuko, Hirano Ikuo, Hasegawa Atsushi, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Communications Biology. 2023; 6 (1): 875. doi:10.1038/s42003-023-05251-w  
69.   Orui Masatsugu, Saeki Suzuka, Kozakai Yuki, et al. The Impact of the COVID-19 Pandemic on Suicide Rate Trends in the Tsunami-Disaster-Affected Area Following the Great East Japan Earthquake. Crisis. 2023; 44 (2): 93-99. doi:10.1027/0227-5910/a000832  
70.   Oikawa Daiki, Fukui Kohei, Aoki Yuichi, et al. Enterocloster alcoholdehydrogenati sp. nov., a Novel Bacterial Species Isolated from the Feces of a Patient with Alcoholism. Current Microbiology. 2023; 80 (5): 187. doi:10.1007/s00284-023-03285-1  
71.   Hashimoto Chiaki, Shigeta Shogo, Shimada Muneaki, et al. Diagnostic Performance of Preoperative Imaging in Endometrial Cancer. Current Oncology. 2023; 30 (9): 8233-8244. doi:10.3390/curroncol30090597  
72.   Tatara Yota, Yamazaki Hiromi, Katsuoka Fumiki, et al. Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment. Current Research in Translational Medicine. 2023; 71 (1): 103367. doi:10.1016/j.retram.2022.103367  
73.   Yu Zhiqian, Sakai Mai, Fukushima Hotaka, et al. Microarray dataset of gene transcription in mouse microglia and peripheral monocytes in contextual fear conditioning. Data in Brief. 2023; 46 : 108862. doi:10.1016/j.dib.2022.108862  
74.   Takahashi So, Hatta Waku, Watanabe Kenta, et al. Prognostic Benefit of Additional Treatment After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma. Digestive Diseases and Sciences. 2023; 68 (5): 2050-2060. doi:10.1007/s10620-022-07746-8  
75.   Ogata Yohei, Hatta Waku, Koike Tomoyuki, et al. Blue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high‐risk patients: Multicenter randomized trial. Digestive Endoscopy. 2023; 35 (7): 835-844. doi:10.1111/den.14538  
76.   Ueno Fumihiko, Murakami Keiko, Nagai Masato, et al. Difficulties in Accessing Medication Records at the Time of a Large-Scale Disaster. Disaster Medicine and Public Health Preparedness. 2023; 17 : e370. doi:10.1017/dmp.2022.301  
77.   Hishinuma Eiji, Narita Yoko, Rico Evelyn Marie Gutiérrez, et al. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity. Drug Metabolism and Disposition. 2023; 51 (2): 165-173. doi:10.1124/dmd.122.001045  
78.   Sato Yu, Hishinuma Eiji, Yamazaki Shuki, et al. Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω -Hydroxylation. Drug Metabolism and Disposition. 2023; 51 (12): 1561-1568. doi:10.1124/dmd.123.001389  
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80.   Tsukagoshi Eri, Nakamura Ryosuke, Tanaka Yoichi, et al. Validation of a genotyping technique for a surrogate marker of HLA-B58:01 for allopurinol-induced Stevens–Johnson syndrome and toxic epidermal necrolysis in the Japanese population. Drug Metabolism and Pharmacokinetics. 2023; 49 : 100495. doi:10.1016/j.dmpk.2023.100495  
81.   Murakami Keiko, Kuriyama Shinichi, Hashimoto Hideki. Economic, cognitive, and social paths of education to health-related behaviors: evidence from a population-based study in Japan. Environmental Health and Preventive Medicine. 2023; 28 (1): 22-00178. doi:10.1265/ehpm.22-00178  
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83.   Usuzaki Takuma, Takahashi Kengo, Takagi Hidenobu, et al. Efficacy of exponentiation method with a convolutional neural network for classifying lung nodules on CT images by malignancy level. European Radiology. 2023; 33 (12): 9309-9319. doi:10.1007/s00330-023-09946-w  
84.   Inoue-Yanagimachi Maki, Himori Noriko, Uchida Keiko, et al. Changes in glial cells and neurotrophic factors due to rotenone-induced oxidative stress in Nrf2 knockout mice. Experimental Eye Research. 2023; 226 : 109314. doi:10.1016/j.exer.2022.109314  
85.   Zhang Anqi, Suzuki Takafumi, Adachi Saki, et al. Nrf2 activation improves experimental rheumatoid arthritis. Free Radical Biology and Medicine. 2023; 207 : 279-295. doi:10.1016/j.freeradbiomed.2023.07.016  
86.   Zhang Lin, Nishi Hafumi, Kinoshita Kengo. Single-cell RNA-seq public data reveal the gene regulatory network landscape of respiratory epithelial and peripheral immune cells in COVID-19 patients. Frontiers in Immunology. 2023; 14 : . doi:10.3389/fimmu.2023.1194614  
87.   Kodama Naoki, Okada Hikaru, Hachisu Masakazu, et al. A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice. Frontiers in Nutrition. 2023; 10 : . doi:10.3389/fnut.2023.1081263  
88.   Suzuki Satoko, Obara Taku, Ishikawa Tomofumi, et al. No association between major congenital malformations and exposure to Kampo medicines containing rhubarb rhizome: A Japanese database study. Frontiers in Pharmacology. 2023; 14 : . doi:10.3389/fphar.2023.1107494  
89.   Li Xue, Ono Chiaki, Warita Noriko, et al. Comprehensive evaluation of machine learning algorithms for predicting sleep–wake conditions and differentiating between the wake conditions before and after sleep during pregnancy based on heart rate variability. Frontiers in Psychiatry. 2023; 14 : . doi:10.3389/fpsyt.2023.1104222  
90.   Murakami Keiko, Kuriyama Shinichi, Hashimoto Hideki. General health literacy, COVID-19-related health literacy, and protective behaviors: evidence from a population-based study in Japan. Frontiers in Public Health. 2023; 11 : . doi:10.3389/fpubh.2023.1208815  
91.   Kobayashi Tomoko, Fujishima Fumiyoshi, Tokodai Kazuaki, et al. Detailed Courses and Pathological Findings of Colonic Perforation without Diverticula in Sisters with Musculocontractural Ehlers–Danlos Syndrome Caused by Pathogenic Variant in CHST14 (mcEDS-CHST14). Genes. 2023; 14 (5): 1079. doi:10.3390/genes14051079  
92.   Tokutomi Tomoharu, Yoshida Akiko, Fukushima Akimune, et al. Stakeholder Perception of the Implementation of Genetic Risk Testing for Twelve Multifactorial Diseases. Genes. 2023; 15 (1): 49. doi:10.3390/genes15010049  
93.   Watarai Gosuke, Suzuki Jun, Motoike Ikuko N, et al. Relationship between age‐related hearing loss and consumption of coffee and tea. Geriatrics & Gerontology International. 2023; 23 (6): 453-456. doi:10.1111/ggi.14589  
94.   Obara Taku, Ishikuro Mami, Ueno Fumihiko, et al. Antihypertensive drug use during pregnancy in Japan. Hypertension Research. 2023; 46 (2): 548-549. doi:10.1038/s41440-022-01101-0  
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